product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Ubiquitin (P4D1) AC
catalog :
sc-8017 AC
quantity :
500 µg/ml, 25% ag
price :
416 USD
clonality :
monoclonal
host :
mouse
conjugate :
agarose
clone name :
P4D1
reactivity :
human, mouse, rat, bovine, fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, other
citations: 33
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:100; loading ...; fig 1a
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5a
Juenemann K, Jansen A, van Riel L, Merkx R, Mulder M, An H, et al. Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies. Sci Rep. 2018;8:1405 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2a
Chiang C, Pauli E, Biryukov J, Feister K, Meng M, White E, et al. The Human Papillomavirus E6 Oncoprotein Targets USP15 and TRIM25 To Suppress RIG-I-Mediated Innate Immune Signaling. J Virol. 2018;92: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Zhu T, Yong X, Xia D, Widagdo J, Anggono V. Ubiquitination Regulates the Proteasomal Degradation and Nuclear Translocation of the Fat Mass and Obesity-Associated (FTO) Protein. J Mol Biol. 2018;430:363-371 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 6d
Li M, Lau Z, Cheung P, Aguilar E, Schneider W, Bozzacco L, et al. TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP). PLoS Pathog. 2017;13:e1006145 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 4e
Cai H, Liu A. Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A. 2016;113:14751-14756 pubmed publisher
  • western blot; mouse; loading ...; fig 10a
Huang S, Zhou A, Nguyen D, Zhang H, Benz E. Protein 4.1R Influences Myogenin Protein Stability and Skeletal Muscle Differentiation. J Biol Chem. 2016;291:25591-25607 pubmed
  • immunocytochemistry; rat; 1:500; loading ...; fig 2b
Shlevkov E, Kramer T, Schapansky J, LaVoie M, Schwarz T. Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility. Proc Natl Acad Sci U S A. 2016;113:E6097-E6106 pubmed
  • western blot; mouse; loading ...; fig s4a
Xiao Y, Tang J, Guo H, Zhao Y, Tang R, Ouyang S, et al. Targeting CBLB as a potential therapeutic approach for disseminated candidiasis. Nat Med. 2016;22:906-14 pubmed publisher
  • western blot; mouse; loading ...; fig 6c
Rackov G, Hernandez Jimenez E, Shokri R, Carmona Rodríguez L, Manes S, Alvarez Mon M, et al. p21 mediates macrophage reprogramming through regulation of p50-p50 NF-?B and IFN-?. J Clin Invest. 2016;126:3089-103 pubmed publisher
  • western blot; mouse; fig 3b
Passalacqua K, Charbonneau M, Donato N, Showalter H, Sun D, Wen B, et al. Anti-infective Activity of 2-Cyano-3-Acrylamide Inhibitors with Improved Drug-Like Properties against Two Intracellular Pathogens. Antimicrob Agents Chemother. 2016;60:4183-96 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 5c
Frum R, Love I, Damle P, Mukhopadhyay N, Palit Deb S, Deb S, et al. Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination. Mol Cancer Res. 2016;14:423-36 pubmed publisher
  • western blot; human; 1:5000; fig 3d
Choi W, de Poot S, Lee J, Kim J, Han D, Kim Y, et al. Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. Nat Commun. 2016;7:10963 pubmed publisher
  • western blot; human; loading ...; fig 3a
Llambi F, Wang Y, Victor B, Yang M, Schneider D, Gingras S, et al. BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation. Cell. 2016;165:421-33 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; fruit fly ; 1:1000; fig 2b
Zhou Z, Xu C, Chen P, Liu C, Pang S, Yao X, et al. Stability of HIB-Cul3 E3 ligase adaptor HIB Is Regulated by Self-degradation and Availability of Its Substrates. Sci Rep. 2015;5:12709 pubmed publisher
  • western blot; bovine; 1:1000
Boutell C, Davido D. A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro. Methods. 2015;90:3-7 pubmed publisher
  • western blot; human
Huo L, Li C, Huang T, Lam Y, Xia W, Tu C, et al. Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. Am J Transl Res. 2014;6:649-63 pubmed
  • immunoprecipitation; human; loading ...; fig 2b
Shim H, Wei M, Brandhorst S, Longo V. Starvation promotes REV1 SUMOylation and p53-dependent sensitization of melanoma and breast cancer cells. Cancer Res. 2015;75:1056-67 pubmed publisher
  • western blot; human; fig 1
Aida K, Hayashi H, Inamura K, Mizuno T, Sugiyama Y. Differential roles of ubiquitination in the degradation mechanism of cell surface-resident bile salt export pump and multidrug resistance-associated protein 2. Mol Pharmacol. 2014;85:482-91 pubmed publisher
Sapir T, Levy T, Kozer N, Shin I, Zamor V, Haffner Krausz R, et al. Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases. Cereb Cortex. 2017;:1-14 pubmed publisher
Wobst H, Wesolowski S, Chadchankar J, Delsing L, Jacobsen S, Mukherjee J, et al. Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro. Front Mol Neurosci. 2017;10:46 pubmed publisher
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher
Chan Y, Gack M. A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity. Nat Immunol. 2016;17:523-30 pubmed publisher
Toruń A, Szymańska E, Castanon I, Wolińska Nizioł L, Bartosik A, Jastrzębski K, et al. Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS ONE. 2015;10:e0130818 pubmed publisher
Hendriks I, D Souza R, Chang J, Mann M, Vertegaal A. System-wide identification of wild-type SUMO-2 conjugation sites. Nat Commun. 2015;6:7289 pubmed publisher
Marsolier J, Perichon M, Debarry J, Villoutreix B, Chluba J, Lopez T, et al. Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation. Nature. 2015;520:378-82 pubmed publisher
Morimoto D, Walinda E, Fukada H, Sou Y, Kageyama S, Hoshino M, et al. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Nat Commun. 2015;6:6116 pubmed publisher
Jin J, Xiao Y, Hu H, Zou Q, Li Y, Gao Y, et al. Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages. Nat Commun. 2015;6:5930 pubmed publisher
Pagotto A, Caballero O, Volkmar N, Devalle S, Simpson A, Lu X, et al. Centrosomal localisation of the cancer/testis (CT) antigens NY-ESO-1 and MAGE-C1 is regulated by proteasome activity in tumour cells. PLoS ONE. 2013;8:e83212 pubmed publisher
Auner H, Moody A, Ward T, Kraus M, Milan E, May P, et al. Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells. PLoS ONE. 2013;8:e74415 pubmed publisher
Marsolier J, Pineau S, Medjkane S, Perichon M, Yin Q, Flemington E, et al. OncomiR addiction is generated by a miR-155 feedback loop in Theileria-transformed leukocytes. PLoS Pathog. 2013;9:e1003222 pubmed publisher
Dimova N, Hathaway N, Lee B, Kirkpatrick D, Berkowitz M, Gygi S, et al. APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1. Nat Cell Biol. 2012;14:168-76 pubmed publisher
Xu G, Paige J, Jaffrey S. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol. 2010;28:868-73 pubmed publisher
product information
Catalog Number :
sc-8017 AC
Product Name :
Ubiquitin (P4D1) AC
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
agarose
Clone Name :
P4D1
Isotype :
IgG1
Size :
500 µg/ml, 25% ag
List Price :
416 USD
Immunogen :
Ubiquitin
Specificity :
mouse, rat, human
Uses :
IP
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA