product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
NFkappaB p65 (F-6) Antibody
catalog :
sc-8008
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-6
reactivity :
African green monkey, human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
citations: 426
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig s7
  • immunocytochemistry; human; fig s6
  • western blot; human; fig 3
Duran C, Lee D, Jung J, Ravi S, Pogue C, Toussaint L, et al. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway. Oncogenesis. 2016;5:e231 pubmed publisher
  • western blot knockout validation; mouse; fig 2
Gao Z, Zhang J, Henagan T, Lee J, Ye X, Wang H, et al. P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. Am J Physiol Endocrinol Metab. 2015;308:E496-505 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 6c
  • western blot; human; 1:1000; loading ...; fig 6a
Pandey S, Shteinfer Kuzmine A, Chalifa Caspi V, Shoshan Barmatz V. Non-apoptotic activity of the mitochondrial protein SMAC/Diablo in lung cancer: Novel target to disrupt survival, inflammation, and immunosuppression. Front Oncol. 2022;12:992260 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 5a
Liu Y, Xu Y, Yao Y, Cao Y, Chen G, Cai Y, et al. I-κB kinase-ε deficiency improves doxorubicin-induced dilated cardiomyopathy by inhibiting the NF-κB pathway. Front Physiol. 2022;13:934899 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7
Ramos H, Bogdanov P, Huerta J, De xe0 s Just A, Hern xe1 ndez C, Sim xf3 R. Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy. Antioxidants (Basel). 2022;11: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 8e
Tan H, Yong Y, Xue Y, Liu H, Furihata T, Shankar E, et al. cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model. iScience. 2022;25:104404 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 1k
  • western blot; human; 1:500; loading ...; fig s2b
Formigari G, D xe1 tilo M, Vareda B, Bonfante I, Cavaglieri C, Lopes de Faria J, et al. Renal protection induced by physical exercise may be mediated by the irisin/AMPK axis in diabetic nephropathy. Sci Rep. 2022;12:9062 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 2e
Wu X, Xia T, Shin W, Yu K, Jung W, Herrmann A, et al. Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8. MBio. 2022;13:e0040222 pubmed publisher
  • western blot; rat; 1:2000; loading ...; fig 3a
Ma N, Li G, Fu X. Protective role of activating transcription factor 3 against neuronal damage in rats with cerebral ischemia. Brain Behav. 2022;12:e2522 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7b
Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 3c
  • western blot; rat; 1:1000; loading ...; fig 2a
Yadav A, Huang T, Chen S, Ramasamy T, Hsueh Y, Lin S, et al. Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NFκB to promote axonal regeneration and remyelination. J Neuroinflammation. 2021;18:238 pubmed publisher
  • western blot; human; loading ...; fig 4b
Zheng J, Yao L, Zhou Y, Gu X, Wang C, Bao K, et al. A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis. Cell Death Dis. 2021;12:871 pubmed publisher
  • western blot; human; loading ...; fig 5a
Lassiter R, Merchen T, Fang X, Wang Y. Protective Role of Kynurenine 3-Monooxygenase in Allograft Rejection and Tubular Injury in Kidney Transplantation. Front Immunol. 2021;12:671025 pubmed publisher
  • western blot; human; loading ...; fig 5c
Huang S, Luo W, Wu G, Shen Q, Zhuang Z, Yang D, et al. Inhibition of CDK9 attenuates atherosclerosis by inhibiting inflammation and phenotypic switching of vascular smooth muscle cells. Aging (Albany NY). 2021;13:14892-14909 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2d
Choi E, Jeong J, Jang H, Ahn Y, Kim K, An H, et al. Skeletal Lipocalin-2 Is Associated with Iron-Related Oxidative Stress in ob/ob Mice with Sarcopenia. Antioxidants (Basel). 2021;10: pubmed publisher
  • chromatin immunoprecipitation; human; loading ...
Yi S, Jang Y, Kim H, Lee K, Lee H, Kim Y, et al. The KDM4B-CCAR1-MED1 axis is a critical regulator of osteoclast differentiation and bone homeostasis. Bone Res. 2021;9:27 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 8b
Cao Y, Li L, Liu Y, Chen G, Tao Z, Wang R, et al. I-κB Kinase-ε Deficiency Attenuates the Development of Angiotensin II-Induced Myocardial Hypertrophy in Mice. Oxid Med Cell Longev. 2021;2021:6429197 pubmed publisher
  • western blot; mouse; fig 7b
Tao S, Yang Y, Li J, Wang H, Ma Y. Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPARα Signals. Oxid Med Cell Longev. 2021;2021:6610124 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 4b
  • western blot; mouse; 1:400; loading ...; fig 4a
Fan J, Duan L, Wu N, Xu X, Xin J, Jiang S, et al. Baicalin Ameliorates Pancreatic Fibrosis by Inhibiting the Activation of Pancreatic Stellate Cells in Mice with Chronic Pancreatitis. Front Pharmacol. 2020;11:607133 pubmed publisher
  • western blot; human; loading ...
Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3a
Schürmann M, Greiner J, Volland Thurn V, Oppel F, Kaltschmidt C, Sudhoff H, et al. Stem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS. Cells. 2020;9: pubmed publisher
  • western blot; African green monkey; loading ...; fig 5h
  • immunocytochemistry; human; loading ...; fig 5g
  • western blot; human; loading ...; fig 4c
Lee C, Aizawa K, Jiang J, Kung S, Jain R. JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli. Sci Adv. 2019;5:eaav0318 pubmed publisher
  • western blot; human; loading ...; fig 4a
Zoi I, Karamouzis M, Xingi E, Sarantis P, Thomaidou D, Lembessis P, et al. Combining RANK/RANKL and ERBB-2 targeting as a novel strategy in ERBB-2-positive breast carcinomas. Breast Cancer Res. 2019;21:132 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 2f
Managò A, Audrito V, Mazzola F, Sorci L, Gaudino F, Gizzi K, et al. Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation. Nat Commun. 2019;10:4116 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4g
Gal H, Lysenko M, Stroganov S, Vadai E, Youssef S, Tzadikevitch Geffen K, et al. Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019;38:e100849 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 4b
El Kott A, Shati A, Al Kahtani M, Alqahtani S. Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway. Anal Cell Pathol (Amst). 2019;2019:9627810 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4f
Bando H, Pradipta A, Iwanaga S, Okamoto T, Okuzaki D, Tanaka S, et al. CXCR4 regulates Plasmodium development in mouse and human hepatocytes. J Exp Med. 2019;: pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 9
Almeer R, AlBasher G, Alarifi S, Alkahtani S, Ali D, Abdel Moneim A. Royal jelly attenuates cadmium-induced nephrotoxicity in male mice. Sci Rep. 2019;9:5825 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s5b
Herb M, Gluschko A, Wiegmann K, Farid A, Wolf A, Utermöhlen O, et al. Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO. Sci Signal. 2019;12: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7f
Keklikoglou I, Cianciaruso C, Güç E, Squadrito M, Spring L, Tazzyman S, et al. Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol. 2019;21:190-202 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 7b
Cao Y, Xu Y, Auchoybur M, Chen W, He S, Qin W, et al. Regulatory role of IKKɑ in myocardial ischemia/reperfusion injury by the determination of M1 versus M2 polarization of macrophages. J Mol Cell Cardiol. 2018;123:1-12 pubmed publisher
  • western blot; mouse; loading ...; fig 5c
Maturu P, Wei Liang Y, Androutsopoulos V, Jiang W, Wang L, Tsatsakis A, et al. Quercetin attenuates the hyperoxic lung injury in neonatal mice: Implications for Bronchopulmonary dysplasia (BPD). Food Chem Toxicol. 2018;114:23-33 pubmed publisher
  • western blot; human; 1:500; loading ...; fig s3g
Han B, Zhou B, Qu Y, Gao B, Xu Y, Chung S, et al. FOXC1-induced non-canonical WNT5A-MMP7 signaling regulates invasiveness in triple-negative breast cancer. Oncogene. 2018;37:1399-1408 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 5d
Jiang Z, Wang W, Guo C. Tetrahydroxy stilbene glucoside ameliorates H2O2-induced human brain microvascular endothelial cell dysfunction in vitro by inhibiting oxidative stress and inflammatory responses. Mol Med Rep. 2017;16:5219-5224 pubmed publisher
  • immunocytochemistry; human; 1:150; loading ...; fig 2b
  • western blot; human; 1:250; loading ...; fig 2a
Martinez Moreno J, Herencia C, de Oca A, Díaz Tocados J, Vergara N, Gómez Luna M, et al. High phosphate induces a pro-inflammatory response by vascular smooth muscle cells and modulation by vitamin D derivatives. Clin Sci (Lond). 2017;131:1449-1463 pubmed publisher
  • western blot; mouse; 1:500; fig 4C
Li F, Zhang N, Li Z, Deng L, Zhang J, Zhou Y. Toll-like receptor 2 agonist exacerbates renal injury in diabetic mice. Exp Ther Med. 2017;13:495-502 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4b
Vodret S, Bortolussi G, Jašprová J, Vitek L, Muro A. Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model. J Neuroinflammation. 2017;14:64 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5a
Nagashima H, Shinoda M, Honda K, Kamio N, Watanabe M, Suzuki T, et al. CXCR4 signaling in macrophages contributes to periodontal mechanical hypersensitivity in Porphyromonas gingivalis-induced periodontitis in mice. Mol Pain. 2017;13:1744806916689269 pubmed publisher
  • western blot; human; loading ...; fig 2b
Roberts C, Shahin S, Loeza J, Dellinger T, Williams J, Glackin C. Disruption of TWIST1-RELA binding by mutation and competitive inhibition to validate the TWIST1 WR domain as a therapeutic target. BMC Cancer. 2017;17:184 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 3f
  • western blot; human; 1:1000; loading ...; fig 3d
Tian Y, Wu X, Guo S, Ma L, Huang W, Zhao X. Minocycline attenuates sevoflurane-induced cell injury via activation of Nrf2. Int J Mol Med. 2017;39:869-878 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a
Daks A, Petukhov A, Fedorova O, Shuvalov O, Merkulov V, Vasileva E, et al. E3 ubiquitin ligase Pirh2 enhances tumorigenic properties of human non-small cell lung carcinoma cells. Genes Cancer. 2016;7:383-393 pubmed publisher
  • immunocytochemistry; rat; 1:500; loading ...; fig 5c
König H, Schwamborn R, Andresen S, Kinsella S, Watters O, Fenner B, et al. NF-κB regulates neuronal ankyrin-G via a negative feedback loop. Sci Rep. 2017;7:42006 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 5b
  • immunocytochemistry; mouse; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 5f
Lee E, Lee T, Kim J, Park A, Ra E, Kang S, et al. CNBP acts as a key transcriptional regulator of sustained expression of interleukin-6. Nucleic Acids Res. 2017;45:3280-3296 pubmed publisher
  • western blot; mouse; 1:1000; fig 8a
Jiang S, Ping L, Sun F, Wang X, Sun Z. Protective effect of taraxasterol against rheumatoid arthritis by the modulation of inflammatory responses in mice. Exp Ther Med. 2016;12:4035-4040 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 6b
Meng Z, Zhao T, Zhou K, Zhong Q, Wang Y, Xiong X, et al. A20 Ameliorates Intracerebral Hemorrhage-Induced Inflammatory Injury by Regulating TRAF6 Polyubiquitination. J Immunol. 2017;198:820-831 pubmed publisher
  • western blot; human; fig 3a, b
Sasaki C, Toman J, Vageli D. The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells. PLoS ONE. 2016;11:e0168269 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Zhang H, Wang W, Ren L, Zhao X, Wang Z, Zhuang D, et al. The mTORC2/Akt/NFκB Pathway-Mediated Activation of TRPC6 Participates in Adriamycin-Induced Podocyte Apoptosis. Cell Physiol Biochem. 2016;40:1079-1093 pubmed
  • western blot; mouse; loading ...; fig 2c
Dolunay A, Senol S, Temiz Resitoglu M, Guden D, Sari A, Sahan Firat S, et al. Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-?B, Caspase-1/11, ASC, NOX, and NOS Isoforms. Inflammation. 2017;40:366-386 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7b
Pieterse E, Jeremic I, Czegley C, Weidner D, Biermann M, Veissi S, et al. Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals. Sci Rep. 2016;6:38229 pubmed publisher
  • western blot; mouse; loading ...; fig 7a
Wan X, Wen J, Koo S, Liang L, Garg N. SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease. PLoS Pathog. 2016;12:e1005954 pubmed publisher
  • immunocytochemistry; human; fig s2
Scholefield J, Henriques R, Savulescu A, Fontan E, Boucharlat A, Laplantine E, et al. Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti. Nat Commun. 2016;7:12629 pubmed publisher
  • EMSA; mouse; loading ...; fig 5a
Rackov G, Hernandez Jimenez E, Shokri R, Carmona Rodríguez L, Manes S, Alvarez Mon M, et al. p21 mediates macrophage reprogramming through regulation of p50-p50 NF-?B and IFN-?. J Clin Invest. 2016;126:3089-103 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 3
Moon Y, Kim M, Kim S, Kim T. Apoptotic action of botulinum toxin on masseter muscle in rats: early and late changes in the expression of molecular markers. Springerplus. 2016;5:991 pubmed publisher
  • western blot; human; loading ...; fig 2b
Kwon H, Choi G, Ryu S, Kwon S, Kim S, Booth C, et al. Stepwise phosphorylation of p65 promotes NF-?B activation and NK cell responses during target cell recognition. Nat Commun. 2016;7:11686 pubmed publisher
  • western blot; human; fig s2
Diamant G, Bahat A, Dikstein R. The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes. Nat Commun. 2016;7:11547 pubmed publisher
  • western blot; human; 1:2000; fig 5A
Chen Z, Mei Y, Lei H, Tian R, Ni N, Han F, et al. LYTAK1, a TAK1 inhibitor, suppresses proliferation and epithelial?mesenchymal transition in retinal pigment epithelium cells. Mol Med Rep. 2016;14:145-50 pubmed publisher
  • EMSA; mouse; loading ...; fig 4a
Puthia M, Ambite I, Cafaro C, Butler D, Huang Y, Lutay N, et al. IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections. Sci Transl Med. 2016;8:336ra59 pubmed publisher
  • western blot; human; fig 5
Afsar T, Trembley J, Salomon C, Razak S, Khan M, Ahmed K. Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways. Sci Rep. 2016;6:23077 pubmed publisher
  • western blot; rat; 1:200; fig 2
Rubattu S, Di Castro S, Schulz H, Geurts A, Cotugno M, Bianchi F, et al. Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. J Am Heart Assoc. 2016;5: pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 8
Yeh P, Huang H, Yang C, Yang W, Yang C. Astaxanthin Inhibits Expression of Retinal Oxidative Stress and Inflammatory Mediators in Streptozotocin-Induced Diabetic Rats. PLoS ONE. 2016;11:e0146438 pubmed publisher
  • western blot; human; fig 2
Han M, Lee D, Woo S, Seo B, Min K, Kim S, et al. Galangin sensitizes TRAIL-induced apoptosis through down-regulation of anti-apoptotic proteins in renal carcinoma Caki cells. Sci Rep. 2016;6:18642 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100; fig 3
Yuan D, Chi X, Jin Y, Li X, Ge M, Gao W, et al. Intestinal injury following liver transplantation was mediated by TLR4/NF-κB activation-induced cell apoptosis. Mol Med Rep. 2016;13:1525-32 pubmed publisher
  • immunocytochemistry; human; 1:150; loading ...; fig 4a
Martinez Moreno J, Herencia C, Montes de Oca A, Muñoz Castañeda J, Rodríguez Ortiz M, Díaz Tocados J, et al. Vitamin D modulates tissue factor and protease-activated receptor 2 expression in vascular smooth muscle cells. FASEB J. 2016;30:1367-76 pubmed publisher
  • western blot; mouse; fig 5
Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015;5:18588 pubmed publisher
  • western blot; human; fig 7
Yen Y, Hsiao J, Jiang S, Chang J, Wang S, Shen Y, et al. Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1. Oncotarget. 2015;6:41837-55 pubmed publisher
  • western blot; rat; 1:500; fig 2
Gu Y, Zhang Y, Bi Y, Liu J, Tan B, Gong M, et al. Mesenchymal stem cells suppress neuronal apoptosis and decrease IL-10 release via the TLR2/NFκB pathway in rats with hypoxic-ischemic brain damage. Mol Brain. 2015;8:65 pubmed publisher
  • western blot; mouse; loading ...; fig 2c
Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, et al. BAX inhibitor-1 is a Ca(2+) channel critically important for immune cell function and survival. Cell Death Differ. 2016;23:358-68 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; tbl 2
Seemann S, Lupp A. Administration of a CXCL12 Analog in Endotoxemia Is Associated with Anti-Inflammatory, Anti-Oxidative and Cytoprotective Effects In Vivo. PLoS ONE. 2015;10:e0138389 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Yang S, He H, Ma Q, Zhang Y, Zhu Y, Wan X, et al. Experimental study of the protective effects of SYVN1 against diabetic retinopathy. Sci Rep. 2015;5:14036 pubmed publisher
  • western blot; human; loading ...; fig 5b
Rother S, Bartels M, Schweda A, Resch K, Pallua N, Nourbakhsh M. NF-κB-repressing factor phosphorylation regulates transcription elongation via its interactions with 5'→3' exoribonuclease 2 and negative elongation factor. FASEB J. 2016;30:174-85 pubmed publisher
  • western blot; human; fig 4a
Wang J, Hua W, Huang S, Fan K, Takeshima L, Mao Y, et al. RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb. Oncotarget. 2015;6:30165-77 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:125; loading ...; fig 4a
Leclerc B, Charlebois R, Chouinard G, Allard B, Pommey S, Saad F, et al. CD73 Expression Is an Independent Prognostic Factor in Prostate Cancer. Clin Cancer Res. 2016;22:158-66 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Labouba I, Le Page C, Communal L, Kristessen T, You X, Péant B, et al. Potential Cross-Talk between Alternative and Classical NF-κB Pathways in Prostate Cancer Tissues as Measured by a Multi-Staining Immunofluorescence Co-Localization Assay. PLoS ONE. 2015;10:e0131024 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 5
Giopanou I, Lilis I, Papaleonidopoulos V, Marazioti A, Spella M, Vreka M, et al. Comprehensive Evaluation of Nuclear Factor-κΒ Expression Patterns in Non-Small Cell Lung Cancer. PLoS ONE. 2015;10:e0132527 pubmed publisher
  • western blot; human; 1:1000; fig 5
Panmanee J, Nopparat C, Chavanich N, Shukla M, Mukda S, Song W, et al. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells. J Pineal Res. 2015;59:308-20 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig s2
  • western blot; human; fig 4
Chen P, Wu T, Cheng Y, Chen C, Lee H. NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation. Oncotarget. 2015;6:14274-89 pubmed
  • western blot; human; fig 4
Fei F, Joo E, Tarighat S, Schiffer I, Paz H, Fabbri M, et al. B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3. Oncotarget. 2015;6:11378-94 pubmed
  • immunocytochemistry; human; 1:400
Fallahi Sichani M, Moerke N, Niepel M, Zhang T, Gray N, Sorger P. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Mol Syst Biol. 2015;11:797 pubmed publisher
  • western blot; human; fig 2
Girard B, Regan Anderson T, Welch S, Nicely J, Seewaldt V, OSTRANDER J. Cytoplasmic PELP1 and ERRgamma protect human mammary epithelial cells from Tam-induced cell death. PLoS ONE. 2015;10:e0121206 pubmed publisher
  • immunohistochemistry; rat; 1:100; loading ...; fig 2g
  • western blot; rat; 1:500; loading ...; fig 5a
Wang L, Liu X, Chen H, Chen Z, Weng X, Qiu T, et al. Picroside II protects rat kidney against ischemia/reperfusion-induced oxidative stress and inflammation by the TLR4/NF-κB pathway. Exp Ther Med. 2015;9:1253-1258 pubmed
  • western blot; rat; 1:200
Jin S, Liu Y, Deng S, Liao L, Lin T, Ning Q, et al. Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cyt. Int J Mol Med. 2015;35:1199-212 pubmed publisher
  • western blot; mouse; fig 3b
Choi H, Choi H, Park M, Lee J, Jeong S, Lee S, et al. The inhibitory effects of Geranium thunbergii on interferon-γ- and LPS-induced inflammatory responses are mediated by Nrf2 activation. Int J Mol Med. 2015;35:1237-45 pubmed publisher
  • immunocytochemistry; human; 1:1000
Bawadekar M, de Andrea M, Lo Cigno I, Baldanzi G, Caneparo V, Graziani A, et al. The Extracellular IFI16 Protein Propagates Inflammation in Endothelial Cells Via p38 MAPK and NF-κB p65 Activation. J Interferon Cytokine Res. 2015;35:441-53 pubmed publisher
  • immunocytochemistry; rat; 1:100
Wang Y, Nie M, Lu Y, Wang R, Li J, Yang B, et al. Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro. Int J Mol Med. 2015;35:1067-73 pubmed publisher
  • immunocytochemistry; human; fig 6
Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, et al. The cerebral cavernous malformation 3 gene is necessary for senescence induction. Aging Cell. 2015;14:274-83 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a
Singh V, Wooten A, Jackson J, Maggirwar S, Kiebala M. Investigating the role of ankyrin-rich membrane spanning protein in human immunodeficiency virus type-1 Tat-induced microglia activation. J Neurovirol. 2015;21:186-98 pubmed publisher
  • chromatin immunoprecipitation; human
  • western blot; human; 1:2000
Miyata M, Lee J, Susuki Miyata S, Wang W, Xu H, Kai H, et al. Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M. Nat Commun. 2015;6:6062 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200
Maurya S, Mishra J, Abbas S, Bandyopadhyay S. Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators. Mol Neurobiol. 2016;53:968-82 pubmed publisher
  • western blot; human
Li L, He M, Zhou L, Miao X, Wu F, Huang S, et al. A solute carrier family 22 member 3 variant rs3088442 G→A associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory response. J Biol Chem. 2015;290:5328-40 pubmed publisher
  • western blot; mouse; fig 6
Kim K, Kim N, Kim S, Kim I, Kim K, Lee G. Cyclo(Phe-Pro) produced by the human pathogen Vibrio vulnificus inhibits host innate immune responses through the NF-κB pathway. Infect Immun. 2015;83:1150-61 pubmed publisher
  • immunohistochemistry; mouse; fig 7
Cicchini M, Chakrabarti R, Kongara S, Price S, Nahar R, Lozy F, et al. Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. Autophagy. 2014;10:2036-52 pubmed publisher
  • western blot; rat; 1:100
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product information
Product Name :
NFkappaB p65 (F-6) Antibody
Gene Name :
RELA
Size :
200 µg/ml
Catalog Number :
sc-8008
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
NFkappaB p65
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
1-286 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA