product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PARP-1 Antibody (F-2)
catalog :
sc-8007
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-2
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 146
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2e
Lu C, Wei Y, Wang X, Zhang Z, Yin J, Li W, et al. DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma. Mol Cancer. 2020;19:28 pubmed publisher
  • western blot; human; fig 3c
Ding L, Zhu Q, Zhou F, Tan H, Xu W, Pan C, et al. Identification of viral SIM-SUMO2-interaction inhibitors for treating primary effusion lymphoma. PLoS Pathog. 2019;15:e1008174 pubmed publisher
  • western blot; mouse; loading ...; fig s13h
Moya I, Castaldo S, Van den Mooter L, Soheily S, Sansores Garcia L, Jacobs J, et al. Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. Science. 2019;366:1029-1034 pubmed publisher
  • western blot; human; loading ...; fig 3a
Bentz G, Lowrey A, Horne D, Nguyen V, Satterfield A, Ross T, et al. Using glycyrrhizic acid to target sumoylation processes during Epstein-Barr virus latency. PLoS ONE. 2019;14:e0217578 pubmed publisher
  • western blot; mouse; loading ...; fig 1b
Park B, Chang S, Lee G, Kang B, Kim J, Park H. Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis. Cell Death Dis. 2019;10:16 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Tay L, Krishnan V, Sankar H, Chong Y, Chuang L, Tan T, et al. RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. Cell Rep. 2018;24:1747-1755 pubmed publisher
  • immunoprecipitation; mouse; 1:1000; loading ...; fig 1b
  • western blot; mouse; 1:1000; loading ...; fig 1b
Fu X, Zhang C, Meng H, Zhang K, Shi L, Cao C, et al. Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress. Cell Death Differ. 2018;25:1625-1637 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5n
Chong I, Aronson L, Bryant H, Gulati A, Campbell J, Elliott R, et al. Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer. Gut. 2018;67:1780-1792 pubmed publisher
  • western blot; human; loading ...; fig 3f
Shuang W, Hou L, Zhu Y, Li Q, Hu W. Mcl-1 stabilization confers resistance to taxol in human gastric cancer. Oncotarget. 2017;8:82981-82990 pubmed publisher
  • western blot; human; loading ...; fig 2e
Sykora P, Kanno S, Akbari M, Kulikowicz T, Baptiste B, Leandro G, et al. DNA Polymerase Beta Participates in Mitochondrial DNA Repair. Mol Cell Biol. 2017;37: pubmed publisher
  • western blot; human; loading ...; fig 1d
Zhao H, Zhang L, Zhang Y, Zhao L, Wan Q, Wang B, et al. Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells. Oncotarget. 2017;8:36383-36398 pubmed publisher
  • western blot; human; loading ...; fig 2c
Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, et al. RAD51 interconnects between DNA replication, DNA repair and immunity. Nucleic Acids Res. 2017;45:4590-4605 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s4a
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O Neil N, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nat Commun. 2017;8:14432 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6d
Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina J, et al. ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain. Sci Rep. 2017;7:41290 pubmed publisher
  • western blot; human; loading ...; fig 4c
Chhabra A, Mukherji B, Batra D. Activation induced cell death (AICD) of human melanoma antigen-specific TCR engineered CD8 T cells involves JNK, Bim and p53. Expert Opin Ther Targets. 2017;21:117-129 pubmed publisher
  • western blot; human; loading ...; fig 6e
Fang Y, Kong Y, Xi J, Zhu M, Zhu T, Jiang T, et al. Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity. Oncotarget. 2016;7:79327-79341 pubmed publisher
  • western blot; human; loading ...; fig 4h
Zhao X, Li L, Wang X, Fu R, Lv Y, Jin W, et al. Inhibition of Snail Family Transcriptional Repressor 2 (SNAI2) Enhances Multidrug Resistance of Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0164752 pubmed publisher
  • western blot; human; loading ...; fig 5b
Alexander Savino C, Hayden M, Richardson C, Zhao J, Poligone B. Doxycycline is an NF-κB inhibitor that induces apoptotic cell death in malignant T-cells. Oncotarget. 2016;7:75954-75967 pubmed publisher
  • western blot; mouse; loading ...; fig 5
Figueroa González G, García Castillo V, Coronel Hernández J, López Urrutia E, León Cabrera S, Arias Romero L, et al. Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer. J Cancer. 2016;7:1632-1644 pubmed
  • western blot; mouse; 1:500; loading ...; fig 4c
Jiao Z, Wu J, Liu C, Wen B, Zhao W, Du X. Nicotinic ?7 receptor inhibits the acylation stimulating protein?induced production of monocyte chemoattractant protein?1 and keratinocyte?derived chemokine in adipocytes by modulating the p38 kinase and nuclear factor??B signaling pathways. Mol Med Rep. 2016;14:2959-66 pubmed publisher
  • western blot; human; 1:500; fig 4
Fabbri R, Macciocca M, Vicenti R, Paradisi R, Klinger F, Pasquinelli G, et al. Doxorubicin and cisplatin induce apoptosis in ovarian stromal cells obtained from cryopreserved human ovarian tissue. Future Oncol. 2016;12:1699-711 pubmed publisher
  • western blot; human; 1:1000; fig 3
Du R, Liu Z, Hou X, Fu G, An N, Wang L. Trichostatin A potentiates genistein-induced apoptosis and reverses EMT in HEp2 cells. Mol Med Rep. 2016;13:5045-52 pubmed publisher
  • western blot; human; fig 2c
Garcia C, Videla Richardson G, Dimopoulos N, Fernandez Espinosa D, Miriuka S, Sevlever G, et al. Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. PLoS ONE. 2016;11:e0152607 pubmed publisher
  • western blot; human; fig 4
Hung M, Chen Y, Chu P, Shih C, Yu H, Tai W, et al. Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential. Oncogene. 2016;35:4891-902 pubmed publisher
  • western blot; human; 1:1000; fig s1
Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed publisher
  • western blot; human; fig 1c
Mir R, Bele A, Mirza S, Srivastava S, Olou A, Ammons S, et al. A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression. Mol Cell Biol. 2015;36:886-99 pubmed publisher
  • western blot; human; fig 1
Borriello A, Naviglio S, Bencivenga D, Caldarelli I, Tramontano A, Speranza M, et al. Histone Deacetylase Inhibitors Increase p27(Kip1) by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation. Oxid Med Cell Longev. 2016;2016:2481865 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig st1
Hwang J, Sung W, Tu H, Hsieh K, Yeh C, Chen C, et al. The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma. PLoS ONE. 2015;10:e0139435 pubmed publisher
  • western blot; human; fig 1c
Hilton B, Li Z, Musich P, Wang H, Cartwright B, SERRANO M, et al. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015;60:35-46 pubmed publisher
  • western blot; human; loading ...; fig 4
Weaver A, Cooper T, Rodriguez M, Trummell H, Bonner J, Rosenthal E, et al. DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma. Oncotarget. 2015;6:26995-7007 pubmed publisher
  • western blot; human; loading ...; fig st2
Tiffen J, Gunatilake D, Gallagher S, Gowrishankar K, Heinemann A, Cullinane C, et al. Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes. Oncotarget. 2015;6:27023-36 pubmed publisher
  • western blot; human; fig 6
Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed publisher
  • western blot; human; 1:2000; fig 6
Sarojini S, Pecora A, Milinovikj N, Barbiere J, Gupta S, Hussain Z, et al. A combination of high dose rate (10X FFF/2400 MU/min/10 MV X-rays) and total low dose (0.5 Gy) induces a higher rate of apoptosis in melanoma cells in vitro and superior preservation of normal melanocytes. Melanoma Res. 2015;25:376-89 pubmed publisher
  • western blot; human; fig 2
Heinemann A, Cullinane C, De Paoli Iseppi R, Wilmott J, Gunatilake D, Madore J, et al. Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling. Oncotarget. 2015;6:21507-21 pubmed
  • western blot; human
Zhang D, Zhu L, Li C, Mu J, Fu Y, Zhu Q, et al. Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction. Basic Res Cardiol. 2015;110:28 pubmed publisher
  • western blot; human
Newman E, Lu F, Bashllari D, Wang L, Opipari A, Castle V. Alternative NHEJ Pathway Components Are Therapeutic Targets in High-Risk Neuroblastoma. Mol Cancer Res. 2015;13:470-82 pubmed publisher
  • western blot; human; fig s3
Kumar S, Das S, Rachagani S, Kaur S, Joshi S, Johansson S, et al. NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer. Oncogene. 2015;34:4879-89 pubmed publisher
  • western blot; human; 1:500
Riggi N, Knoechel B, Gillespie S, Rheinbay E, Boulay G, Suvà M, et al. EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. Cancer Cell. 2014;26:668-681 pubmed publisher
  • western blot; human
Holland W, Chinn D, Lara P, Gandara D, Mack P. Effects of AKT inhibition on HGF-mediated erlotinib resistance in non-small cell lung cancer cell lines. J Cancer Res Clin Oncol. 2015;141:615-26 pubmed publisher
  • western blot; human
Wang Y, Kuramitsu Y, Tokuda K, Baron B, Kitagawa T, Akada J, et al. Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer. PLoS ONE. 2014;9:e109076 pubmed publisher
  • western blot; human; 1:1000
Benatti P, Dolfini D, Vigano A, Ravo M, Weisz A, Imbriano C. Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Nucleic Acids Res. 2011;39:5356-68 pubmed publisher
  • western blot; human
Stang S, Lopez Campistrous A, Song X, Dower N, Blumberg P, Wender P, et al. A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells. Exp Hematol. 2009;37:122-134 pubmed publisher
  • western blot; human
Drosopoulos K, Roberts M, Cermak L, Sasazuki T, Shirasawa S, Andera L, et al. Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. J Biol Chem. 2005;280:22856-67 pubmed
Kim J, Yang J, Kim E. SIRT1 and AROS suppress doxorubicin-induced apoptosis via inhibition of GSK3β activity in neuroblastoma cells. Anim Cells Syst (Seoul). 2020;24:53-59 pubmed publisher
Lee J, Lee H, Ryu K, Kim M, Ko D, Chung K, et al. KCP10043F Represses the Proliferation of Human Non-Small Cell Lung Cancer Cells by Caspase-Mediated Apoptosis via STAT3 Inactivation. J Clin Med. 2020;9: pubmed publisher
Videla Richardson G, Furmento V, Garcia C, Morris Hanon O, Sevlever G, Romorini L, et al. Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine. BMC Mol Cell Biol. 2019;20:40 pubmed publisher
Ricciardi L, Col J, Casolari P, Memoli D, Conti V, Vatrella A, et al. Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients. Int J Chron Obstruct Pulmon Dis. 2018;13:3173-3190 pubmed publisher
Ding L, Li J, Li W, Fang Z, Li N, Wu S, et al. p53- and ROS-mediated AIF pathway involved in TGEV-induced apoptosis. J Vet Med Sci. 2018;80:1775-1781 pubmed publisher
Zhang L, Li X, Chao Y, He R, Liu J, Yuan Y, et al. KLF4, a miR-32-5p targeted gene, promotes cisplatin-induced apoptosis by upregulating BIK expression in prostate cancer. Cell Commun Signal. 2018;16:53 pubmed publisher
Zhang D, Lin J, Chao Y, Zhang L, Jin L, Li N, et al. Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression. J Exp Clin Cancer Res. 2018;37:176 pubmed publisher
Ribas R, Pancholi S, Rani A, Schuster E, Guest S, Nikitorowicz Buniak J, et al. Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer. Breast Cancer Res. 2018;20:44 pubmed publisher
Zmuda F, Blair A, Liuzzi M, Malviya G, Chalmers A, Lewis D, et al. An 18F-Labeled Poly(ADP-ribose) Polymerase Positron Emission Tomography Imaging Agent. J Med Chem. 2018;61:4103-4114 pubmed publisher
Dilworth D, Gudavicius G, Xu X, Boyce A, O Sullivan C, Serpa J, et al. The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability. Nucleic Acids Res. 2018;46:2459-2478 pubmed publisher
Gong J, Huang M, Wang F, Ma X, Liu H, Tu Y, et al. RBM45 competes with HDAC1 for binding to FUS in response to DNA damage. Nucleic Acids Res. 2017;45:12862-12876 pubmed publisher
Liu C, Hua K, Li K, Kao H, Hong R, Ko J, et al. Histone Methyltransferase G9a Drives Chemotherapy Resistance by Regulating the Glutamate-Cysteine Ligase Catalytic Subunit in Head and Neck Squamous Cell Carcinoma. Mol Cancer Ther. 2017;16:1421-1434 pubmed publisher
García Castillo V, López Urrutia E, Villanueva Sánchez O, Avila Rodriguez M, Zentella Dehesa A, Cortés González C, et al. Targeting Metabolic Remodeling in Triple Negative Breast Cancer in a Murine Model. J Cancer. 2017;8:178-189 pubmed publisher
Massihnia D, Avan A, Funel N, Maftouh M, van Krieken A, Granchi C, et al. Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer. J Hematol Oncol. 2017;10:9 pubmed publisher
Cocchiarella F, Latella M, Basile V, Miselli F, Galla M, Imbriano C, et al. Transcriptionally regulated and nontoxic delivery of the hyperactive Sleeping Beauty Transposase. Mol Ther Methods Clin Dev. 2016;3:16038 pubmed publisher
Thinon E, Morales Sanfrutos J, Mann D, Tate E. N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells. ACS Chem Biol. 2016;11:2165-76 pubmed publisher
Yang X, Sun D, Dong C, Tian Y, Gao Z, Wang L. Pinin associates with prognosis of hepatocellular carcinoma through promoting cell proliferation and suppressing glucose deprivation-induced apoptosis. Oncotarget. 2016;7:39694-39704 pubmed publisher
Krönung S, Beyer U, Chiaramonte M, Dolfini D, Mantovani R, Dobbelstein M. LTR12 promoter activation in a broad range of human tumor cells by HDAC inhibition. Oncotarget. 2016;7:33484-97 pubmed publisher
Becker A, Zhang P, Allmann L, Meilinger D, Bertulat B, Eck D, et al. Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure. J Biol Chem. 2016;291:4873-81 pubmed publisher
Nizialek E, Sankunny M, Niazi F, Eng C. Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability. Nucleic Acids Res. 2016;44:3586-94 pubmed publisher
Liao M, Lai J, Kuo M, Lu R, Lin C, Cheng P, et al. An anti-EpCAM antibody EpAb2-6 for the treatment of colon cancer. Oncotarget. 2015;6:24947-68 pubmed publisher
Liu M, Park J, Wu X, Li Y, Tran Q, Mun K, et al. Shen-Kang protects 5/6 nephrectomized rats against renal injury by reducing oxidative stress through the MAPK signaling pathways. Int J Mol Med. 2015;36:975-84 pubmed publisher
Selmi T, Alecci C, dell Aquila M, Montorsi L, Martello A, Guizzetti F, et al. ZFP36 stabilizes RIP1 via degradation of XIAP and cIAP2 thereby promoting ripoptosome assembly. BMC Cancer. 2015;15:357 pubmed publisher
Jiao H, Xu Y, Li J, Wang W, Mei Z, Long X, et al. Prognostic significance of Cbx4 expression and its beneficial effect for transarterial chemoembolization in hepatocellular carcinoma. Cell Death Dis. 2015;6:e1689 pubmed publisher
Sato M, Rodríguez Barrueco R, Yu J, Do C, Silva J, Gautier J. MYC is a critical target of FBXW7. Oncotarget. 2015;6:3292-305 pubmed
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Hou J, Huang Y, He W, Yan Z, Fan L, Liu M, et al. Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells. Cell Death Dis. 2014;5:e1400 pubmed publisher
Yang H, Lawrence H, Kazi A, Gevariya H, Patel R, Luo Y, et al. Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation. Oncotarget. 2014;5:2947-61 pubmed
Feng Q, Zhang Z, Shea M, Creighton C, Coarfa C, Hilsenbeck S, et al. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Res. 2014;24:809-19 pubmed publisher
Kim H, Lee H, Oh Y, Choi S, Hong S, Kim H, et al. The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Nat Commun. 2014;5:3351 pubmed publisher
Hu W, Jin L, Jiang C, Long G, Scolyer R, Wu Q, et al. AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma. Cell Death Dis. 2013;4:e914 pubmed publisher
Belluti S, Basile V, Benatti P, Ferrari E, Marverti G, Imbriano C. Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-II? by bis-DemethoxyCurcumin in cancer cells. Cell Death Dis. 2013;4:e756 pubmed publisher
Shin S, Jing K, Jeong S, Kim N, Song K, Heo J, et al. The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53. Biomed Res Int. 2013;2013:568671 pubmed publisher
Hong Z, Jiang J, Ma J, Dai S, Xu T, Li H, et al. The role of hnRPUL1 involved in DNA damage response is related to PARP1. PLoS ONE. 2013;8:e60208 pubmed publisher
Jungkunz Stier I, Zekl M, Stühmer T, Einsele H, Seggewiss Bernhardt R. Modulation of natural killer cell effector functions through lenalidomide/dasatinib and their combined effects against multiple myeloma cells. Leuk Lymphoma. 2014;55:168-76 pubmed publisher
Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, et al. Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol. 2013;20:347-54 pubmed publisher
Sims J, Ganguly S, Bennett H, Friend J, Tepe J, Plattner R. Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-?B and HSP27/p38/AKT pathways and by inhibiting ABCB1. PLoS ONE. 2013;8:e55509 pubmed publisher
Hewish M, Martin S, Elliott R, Cunningham D, Lord C, Ashworth A. Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress. Br J Cancer. 2013;108:983-92 pubmed publisher
Basile V, Belluti S, Ferrari E, Gozzoli C, Ganassi S, Quaglino D, et al. bis-Dehydroxy-Curcumin triggers mitochondrial-associated cell death in human colon cancer cells through ER-stress induced autophagy. PLoS ONE. 2013;8:e53664 pubmed publisher
Crotty T, Nakano T, Stafforini D, Topham M. Diacylglycerol kinase ? modulates Akt phosphorylation through pleckstrin homology domain leucine-rich repeat protein phosphatase 2 (PHLPP2). J Biol Chem. 2013;288:1439-47 pubmed publisher
Li F, Tian X, Zhou Y, Zhu L, Wang B, Ding M, et al. Dysregulated expression of secretogranin III is involved in neurotoxin-induced dopaminergic neuron apoptosis. J Neurosci Res. 2012;90:2237-46 pubmed publisher
Lee Y, Yu Y, Gunawardena H, Xie L, Chen X. BCLAF1 is a radiation-induced H2AX-interacting partner involved in ?H2AX-mediated regulation of apoptosis and DNA repair. Cell Death Dis. 2012;3:e359 pubmed publisher
Sfikas A, Batsi C, Tselikou E, Vartholomatos G, Monokrousos N, Pappas P, et al. The canonical NF-?B pathway differentially protects normal and human tumor cells from ROS-induced DNA damage. Cell Signal. 2012;24:2007-23 pubmed publisher
Sen S, Kawahara B, Chaudhuri G. Maintenance of higher H?O? levels, and its mechanism of action to induce growth in breast cancer cells: important roles of bioactive catalase and PP2A. Free Radic Biol Med. 2012;53:1541-51 pubmed publisher
Huang X, Dong Y, Bey E, Kilgore J, Bair J, Li L, et al. An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis. Cancer Res. 2012;72:3038-47 pubmed publisher
Galia A, Calogero A, Condorelli R, Fraggetta F, La Corte A, Ridolfo F, et al. PARP-1 protein expression in glioblastoma multiforme. Eur J Histochem. 2012;56:e9 pubmed publisher
Tsai W, Wang P, Lin S, Wu I, Ko Y, Chen Y, et al. Ser-634 and Ser-636 of Kaposi's Sarcoma-Associated Herpesvirus RTA are Involved in Transactivation and are Potential Cdk9 Phosphorylation Sites. Front Microbiol. 2012;3:60 pubmed publisher
Ding L, Xu X, Huang Y, Li Z, Zhang K, Chen G, et al. Transmissible gastroenteritis virus infection induces apoptosis through FasL- and mitochondria-mediated pathways. Vet Microbiol. 2012;158:12-22 pubmed publisher
Zhu X, Fu A, Luo K. A high-throughput fluorescence resonance energy transfer (FRET)-based endothelial cell apoptosis assay and its application for screening vascular disrupting agents. Biochem Biophys Res Commun. 2012;418:641-6 pubmed publisher
Oh Y, Jeon Y, Hong G, Kim I, Woo H, Jung Y. Regulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cells. Cell Death Differ. 2012;19:1196-207 pubmed publisher
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Jing K, Song K, Shin S, Kim N, Jeong S, Oh H, et al. Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53. Autophagy. 2011;7:1348-58 pubmed publisher
Chinn D, Holland W, Yoon J, Zwerdling T, Mack P. Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines. Pediatr Blood Cancer. 2012;58:885-90 pubmed publisher
Liang D, Qin Y, Zhao W, Zhai X, Guo Z, Wang R, et al. S-allylmercaptocysteine effectively inhibits the proliferation of colorectal cancer cells under in vitro and in vivo conditions. Cancer Lett. 2011;310:69-76 pubmed publisher
Li Z, Zhang Z, Xie J, Li X, Tian J, Cai T, et al. Na/K-ATPase mimetic pNaKtide peptide inhibits the growth of human cancer cells. J Biol Chem. 2011;286:32394-403 pubmed publisher
Xie Z, Bi C, Cheong L, Liu S, Huang G, Zhou J, et al. Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells. PLoS ONE. 2011;6:e21583 pubmed publisher
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Glienke W, Hausmann E, Bergmann L. Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines. Tumour Biol. 2011;32:493-500 pubmed publisher
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product information
Product Name :
PARP-1 (F-2) Antibody
Gene Name :
PARP1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-8007
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
PARP-1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
764-1014 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA