product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ERalpha (F-10) Antibody
catalog :
sc-8002
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-10
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation, immunohistochemistry knockout validation
citations: 126
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:250; loading ...; fig 5a
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 5a
Zhang Z, Park J, Ahn I, Diamante G, Sivakumar N, Arneson D, et al. Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice. elife. 2021;10: pubmed publisher
  • western blot knockout validation; human; fig 1
Kavlashvili T, Jia Y, Dai D, Meng X, Thiel K, Leslie K, et al. Inverse Relationship between Progesterone Receptor and Myc in Endometrial Cancer. PLoS ONE. 2016;11:e0148912 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1f
Nittoli V, Colella M, Porciello A, Reale C, Roberto L, Russo F, et al. Multi Species Analyses Reveal Testicular T3 Metabolism and Signalling as a Target of Environmental Pesticides. Cells. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; loading ...
Servetto A, Kollipara R, Formisano L, Lin C, Lee K, Sudhan D, et al. Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer. Clin Cancer Res. 2021;27:4379-4396 pubmed publisher
  • western blot; human; loading ...; fig 3b
Vardaki I, Ceder S, Rutishauser D, Baltatzis G, Foukakis T, Panaretakis T. Periostin is identified as a putative metastatic marker in breast cancer-derived exosomes. Oncotarget. 2016;7:74966-74978 pubmed publisher
  • western blot; human; fig 2
Dhamad A, Zhou Z, Zhou J, Du Y. Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction. PLoS ONE. 2016;11:e0160312 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig 1
Calaf G, Abarca Quinones J. Ras protein expression as a marker for breast cancer. Oncol Lett. 2016;11:3637-3642 pubmed
  • western blot; human; fig 1
Simigdala N, Gao Q, Pancholi S, Roberg Larsen H, Zvelebil M, Ribas R, et al. Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer. Breast Cancer Res. 2016;18:58 pubmed publisher
  • western blot; human; 1:750; fig 1
Thakkar A, Wang B, Picon Ruiz M, Buchwald P, Ince T. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer. Breast Cancer Res Treat. 2016;157:77-90 pubmed publisher
  • western blot; human; 1:200; fig 2
Wunsch E, Klak M, Wasik U, Milkiewicz M, Blatkiewicz M, Urasinska E, et al. Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR. J Immunol Res. 2015;2015:571353 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 3c
Xue X, Yang Y, Zhang A, Fong K, Kim J, Song B, et al. LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer. Oncogene. 2016;35:2746-55 pubmed publisher
  • western blot; human; fig 3
Ma S, Yin N, Qi X, Pfister S, Zhang M, Ma R, et al. Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER). Oncotarget. 2015;6:13320-33 pubmed
  • western blot; human; loading ...; fig 1a
Falkenberg N, Anastasov N, Schaub A, Radulovic V, Schmitt M, Magdolen V, et al. Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221. Oncotarget. 2015;6:8103-14 pubmed
  • western blot; human; 1:1000; fig 4
Carnesecchi J, Malbouyres M, de Mets R, Balland M, Beauchef G, Vié K, et al. Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30. PLoS ONE. 2015;10:e0120672 pubmed publisher
  • western blot; human; loading ...; fig s2b
Albanito L, Lappano R, Madeo A, Chimento A, Prossnitz E, Cappello A, et al. Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts. Environ Health Perspect. 2015;123:493-9 pubmed publisher
  • western blot; mouse; fig 6
Van Bragt M, Hu X, Xie Y, Li Z. RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells. elife. 2014;3:e03881 pubmed publisher
  • western blot; human; 1:200
Oguz Erdogan A, Ozdemirler N, Oyken M, Alper M, Erson Bensan A. ARID3B expression in primary breast cancers and breast cancer-derived cell lines. Cell Oncol (Dordr). 2014;37:289-96 pubmed publisher
  • western blot; human
Samaan S, Tranchevent L, Dardenne E, Polay Espinoza M, Zonta E, Germann S, et al. The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways. Nucleic Acids Res. 2014;42:2197-207 pubmed publisher
  • western blot; human
Rao A, Ziegler Y, McLeod I, Yates J, Nardulli A. Effects of Cu/Zn superoxide dismutase on estrogen responsiveness and oxidative stress in human breast cancer cells. Mol Endocrinol. 2008;22:1113-24 pubmed publisher
  • western blot; human
Baquedano M, Saraco N, Berensztein E, Pepe C, Bianchini M, Levy E, et al. Identification and developmental changes of aromatase and estrogen receptor expression in prepubertal and pubertal human adrenal tissues. J Clin Endocrinol Metab. 2007;92:2215-22 pubmed
  • western blot; human; 1:400; fig 6
Jones L, Li M, Halama E, Ma Y, Lubet R, Grubbs C, et al. Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer. Oncogene. 2005;24:3554-62 pubmed
Karakas B, Aka Y, Giray A, Temel S, Acikbas U, Basaga H, et al. Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells. Cell Death Discov. 2021;7:189 pubmed publisher
Chen J, Yang Y, Russu W, Chan W. The Aryl Hydrocarbon Receptor Undergoes Chaperone-Mediated Autophagy in Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2021;22: pubmed publisher
Zhang Z, Reis F, He Y, Park J, DiVittorio J, Sivakumar N, et al. Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice. Nat Commun. 2020;11:6378 pubmed publisher
Kim Y, Lee G, Han J, Song K, Choi J, Choi Y, et al. UBE2C Overexpression Aggravates Patient Outcome by Promoting Estrogen-Dependent/Independent Cell Proliferation in Early Hormone Receptor-Positive and HER2-Negative Breast Cancer. Front Oncol. 2019;9:1574 pubmed publisher
Bernascone I, González T, Barea M, Carabaña C, Hachimi M, Bosch Fortea M, et al. Sfrp3 modulates stromal-epithelial crosstalk during mammary gland development by regulating Wnt levels. Nat Commun. 2019;10:2481 pubmed publisher
Holding A, Giorgi F, Donnelly A, Cullen A, Nagarajan S, Selth L, et al. VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer. Genome Biol. 2019;20:91 pubmed publisher
Lee E, Wongvipat J, Choi D, Wang P, Lee Y, Zheng D, et al. GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance. elife. 2019;8: pubmed publisher
Xu B, Li Q, Chen N, Zhu C, Meng Q, Ayyanathan K, et al. The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ERα and enhances ERα target gene expression in breast cancer cells. Nucleic Acids Res. 2019;47:2322-2335 pubmed publisher
Simigdala N, Pancholi S, Ribas R, Folkerd E, Liccardi G, Nikitorowicz Buniak J, et al. Abiraterone shows alternate activity in models of endocrine resistant and sensitive disease. Br J Cancer. 2018;119:313-322 pubmed publisher
Chen Z, Ai L, Mboge M, Tu C, McKenna R, Brown K, et al. Differential expression and function of CAIX and CAXII in breast cancer: A comparison between tumorgraft models and cells. PLoS ONE. 2018;13:e0199476 pubmed publisher
Ribas R, Pancholi S, Rani A, Schuster E, Guest S, Nikitorowicz Buniak J, et al. Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer. Breast Cancer Res. 2018;20:44 pubmed publisher
Bak M, FURMANSKI P, Shan N, Lee H, Bao C, Lin Y, et al. Tocopherols inhibit estrogen-induced cancer stemness and OCT4 signaling in breast cancer. Carcinogenesis. 2018;: pubmed publisher
Kovac B, Makela T, Vallenius T. Increased α-actinin-1 destabilizes E-cadherin-based adhesions and associates with poor prognosis in basal-like breast cancer. PLoS ONE. 2018;13:e0196986 pubmed publisher
Pierozan P, Jernerén F, Karlsson O. Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells. Arch Toxicol. 2018;92:1729-1739 pubmed publisher
Chamberlin T, D Amato J, Arendt L. Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity. Breast Cancer Res. 2017;19:128 pubmed publisher
Pierozan P, Karlsson O. PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells. Arch Toxicol. 2018;92:705-716 pubmed publisher
Zhao Y, Laws M, Guillen V, Ziegler Y, Min J, Sharma A, et al. Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors. Cancer Res. 2017;77:5602-5613 pubmed publisher
Smith S, Mellor P, Ward A, Kendall S, McDonald M, Vizeacoumar F, et al. Molecular characterization of breast cancer cell lines through multiple omic approaches. Breast Cancer Res. 2017;19:65 pubmed publisher
Charmsaz S, Hughes E, Bane F, Tibbitts P, McIlroy M, Byrne C, et al. S100? as a serum marker in endocrine resistant breast cancer. BMC Med. 2017;15:79 pubmed publisher
Ban Z, Maurischat P, Benz V, Brix S, Sonnenburg A, Schuler G, et al. High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with aP2-Cre-mediated Deletion of Estrogen Receptor Alpha. Sci Rep. 2017;7:43269 pubmed publisher
Yu L, Liang Y, Cao X, Wang X, Gao H, Lin S, et al. Identification of MYST3 as a novel epigenetic activator of ERα frequently amplified in breast cancer. Oncogene. 2017;36:2910-2918 pubmed publisher
Mao X, Qiao Z, Fan C, Guo A, Yu X, Jin F. Expression pattern and methylation of estrogen receptor ? in breast intraductal proliferative lesions. Oncol Rep. 2016;36:1868-74 pubmed publisher
Sabol M, Trnski D, Uzarević Z, Ozretic P, Musani V, Rafaj M, et al. Combination of cyclopamine and tamoxifen promotes survival and migration of mcf-7 breast cancer cells--interaction of hedgehog-gli and estrogen receptor signaling pathways. PLoS ONE. 2014;9:e114510 pubmed publisher
Falkenberg N, Anastasov N, Rappl K, Braselmann H, Auer G, Walch A, et al. MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion. Br J Cancer. 2013;109:2714-23 pubmed publisher
Guo W, Shiina I, Wang Y, Umeda E, Watanabe C, Uetake S, et al. Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway. Biochem Pharmacol. 2013;86:1272-84 pubmed publisher
López Romero R, Garrido Guerrero E, Rangel López A, Manuel Apolinar L, Pina Sanchez P, Lazos Ochoa M, et al. The cervical malignant cells display a down regulation of ER-? but retain the ER-? expression. Int J Clin Exp Pathol. 2013;6:1594-602 pubmed
Caligiuri I, Toffoli G, Giordano A, Rizzolio F. pRb controls estrogen receptor alpha protein stability and activity. Oncotarget. 2013;4:875-83 pubmed
Johansson H, Sanchez B, Mundt F, Forshed J, Kovács A, Panizza E, et al. Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer. Nat Commun. 2013;4:2175 pubmed publisher
Shishido S, Faulkner E, Beck A, Nguyen T. The effect of antineoplastic drugs in a male spontaneous mammary tumor model. PLoS ONE. 2014;8:e64866 pubmed publisher
Wang L, Qiu X, Hao Q, Li D. Anti-inflammatory effects of a Chinese herbal medicine in atherosclerosis via estrogen receptor ? mediating nitric oxide production and NF-?B suppression in endothelial cells. Cell Death Dis. 2013;4:e551 pubmed publisher
Lucchetti C, Caligiuri I, Toffoli G, Giordano A, Rizzolio F. The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor ? in breast cancer. PLoS ONE. 2013;8:e55355 pubmed publisher
Zonta E, Bittencourt D, Samaan S, Germann S, Dutertre M, Auboeuf D. The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export. Nucleic Acids Res. 2013;41:554-64 pubmed publisher
Akman B, Can T, Erson Bensan A. Estrogen-induced upregulation and 3'-UTR shortening of CDC6. Nucleic Acids Res. 2012;40:10679-88 pubmed publisher
Lake M, Nguyen Q, Ali S, Aboagye E. Development of a novel molecular sensor for imaging estrogen receptor-coactivator protein-protein interactions. PLoS ONE. 2012;7:e44160 pubmed publisher
Guido C, Panza S, Santoro M, Avena P, Panno M, Perrotta I, et al. Estrogen receptor beta (ER?) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene. Cell Cycle. 2012;11:2911-21 pubmed publisher
O Hara J, Varešlija D, McBryan J, Bane F, Tibbitts P, Byrne C, et al. AIB1:ER? transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells. Clin Cancer Res. 2012;18:3305-15 pubmed publisher
Periyasamy Thandavan S, Takhar S, Singer A, Dohn M, Jackson W, Welborn A, et al. Insulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER+ breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein Bim. Breast Cancer Res. 2012;14:R52 pubmed
Burger R, Reith P, Kijanka G, Akujobi V, Abgrall P, Ducree J. Array-based capture, distribution, counting and multiplexed assaying of beads on a centrifugal microfluidic platform. Lab Chip. 2012;12:1289-95 pubmed publisher
González Arenas A, Hansberg Pastor V, Hernández Hernández O, González García T, Henderson Villalpando J, Lemus Hernández D, et al. Estradiol increases cell growth in human astrocytoma cell lines through ER? activation and its interaction with SRC-1 and SRC-3 coactivators. Biochim Biophys Acta. 2012;1823:379-86 pubmed publisher
Jung J, Park S, Lee S, Seo M, Trosko J, Kang K. Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT4 expression. PLoS ONE. 2011;6:e28068 pubmed publisher
McBryan J, Theissen S, Byrne C, Hughes E, Cocchiglia S, Sande S, et al. Metastatic progression with resistance to aromatase inhibitors is driven by the steroid receptor coactivator SRC-1. Cancer Res. 2012;72:548-59 pubmed publisher
Svotelis A, Bianco S, Madore J, Huppé G, Nordell Markovits A, Mes Masson A, et al. H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ER? ligand dependency. EMBO J. 2011;30:3947-61 pubmed publisher
Ranjit S, Khair L, Linehan E, Ucher A, Chakrabarti M, Schrader C, et al. AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected]. J Immunol. 2011;187:2464-75 pubmed publisher
Faratian D, Zweemer A, Nagumo Y, Sims A, Muir M, Dodds M, et al. Trastuzumab and pertuzumab produce changes in morphology and estrogen receptor signaling in ovarian cancer xenografts revealing new treatment strategies. Clin Cancer Res. 2011;17:4451-61 pubmed publisher
Vo T, Jung E, Choi K, Yu F, Jeung E. Estrogen receptor ? is involved in the induction of Calbindin-D(9k) and progesterone receptor by parabens in GH3 cells: a biomarker gene for screening xenoestrogens. Steroids. 2011;76:675-81 pubmed publisher
Aubé M, Larochelle C, Ayotte P. Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines. Environ Res. 2011;111:337-47 pubmed publisher
Wang A, Ji L, Shang W, Li M, Chen L, White R, et al. Expression of GPR30, ER? and ER? in endometrium during window of implantation in patients with polycystic ovary syndrome: a pilot study. Gynecol Endocrinol. 2011;27:251-5 pubmed publisher
Hernández Hernández O, Rodríguez Dorantes M, González Arenas A, Camacho Arroyo I. Progesterone and estradiol effects on SRC-1 and SRC-3 expression in human astrocytoma cell lines. Endocrine. 2010;37:194-200 pubmed publisher
Mumcuoglu M, Bagislar S, Yuzugullu H, Alotaibi H, Senturk S, Telkoparan P, et al. The ability to generate senescent progeny as a mechanism underlying breast cancer cell heterogeneity. PLoS ONE. 2010;5:e11288 pubmed publisher
Wu X, Bogoni A, Yilmaz O, Nuccio S, Wang J, Willner A. Eightfold 40-320 Gbit/s phase-coherent multiplexing and 320-40 Gbit/s demultiplexing using highly nonlinear fibers. Opt Lett. 2010;35:1896-8 pubmed publisher
Barone M, Scavo M, Papagni S, Piscitelli D, Guido R, Di Lena M, et al. ER? expression in normal, adenomatous and carcinomatous tissues of patients with familial adenomatous polyposis. Scand J Gastroenterol. 2010;45:1320-8 pubmed publisher
Zheng Y, John S, Pesavento J, Schultz Norton J, Schiltz R, Baek S, et al. Histone H1 phosphorylation is associated with transcription by RNA polymerases I and II. J Cell Biol. 2010;189:407-15 pubmed publisher
Di Leva G, Gasparini P, Piovan C, Ngankeu A, Garofalo M, Taccioli C, et al. MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer. J Natl Cancer Inst. 2010;102:706-21 pubmed publisher
Li X, Mertens Talcott S, Zhang S, Kim K, Ball J, Safe S. MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells. Endocrinology. 2010;151:2462-73 pubmed publisher
Sobrino A, Oviedo P, Novella S, Laguna Fernandez A, Bueno C, García Pérez M, et al. Estradiol selectively stimulates endothelial prostacyclin production through estrogen receptor-{alpha}. J Mol Endocrinol. 2010;44:237-46 pubmed publisher
Kameda C, Nakamura M, Tanaka H, Yamasaki A, Kubo M, Tanaka M, et al. Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer. Br J Cancer. 2010;102:738-47 pubmed publisher
Colin C, Salamone S, Grillier Vuissoz I, Boisbrun M, Kuntz S, Lecomte J, et al. New troglitazone derivatives devoid of PPAR? agonist activity display an increased antiproliferative effect in both hormone-dependent and hormone-independent breast cancer cell lines. Breast Cancer Res Treat. 2010;124:101-10 pubmed publisher
Sobrino A, Mata M, Laguna Fernandez A, Novella S, Oviedo P, García Pérez M, et al. Estradiol stimulates vasodilatory and metabolic pathways in cultured human endothelial cells. PLoS ONE. 2009;4:e8242 pubmed publisher
Bonéy Montoya J, Ziegler Y, Curtis C, Montoya J, Nardulli A. Long-range transcriptional control of progesterone receptor gene expression. Mol Endocrinol. 2010;24:346-58 pubmed publisher
Sharma I, Dhawan V, Mahajan N, Saha S, Dhaliwal L. In vitro effects of atorvastatin on lipopolysaccharide-induced gene expression in endometriotic stromal cells. Fertil Steril. 2010;94:1639-46.e1 pubmed publisher
Ren Y, Wu L, Frost A, Grizzle W, Cao X, Wan M. Dual effects of TGF-beta on ERalpha-mediated estrogenic transcriptional activity in breast cancer. Mol Cancer. 2009;8:111 pubmed publisher
Seow H, Yip W, Loh H, Ithnin H, Por P, Rohaizak M. Immunohistochemical detection of phospho-Akt, phospho-BAD, HER2 and oestrogen receptors alpha and beta in Malaysian breast cancer patients. Pathol Oncol Res. 2010;16:239-48 pubmed publisher
Penatti C, Porter D, Henderson L. Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms. J Neurosci. 2009;29:12484-96 pubmed publisher
Schultz Norton J, Ziegler Y, Likhite V, Nardulli A. Isolation of proteins associated with the DNA-bound estrogen receptor alpha. Methods Mol Biol. 2009;590:209-21 pubmed publisher
Vo T, Jeung E. An evaluation of estrogenic activity of parabens using uterine calbindin-d9k gene in an immature rat model. Toxicol Sci. 2009;112:68-77 pubmed publisher
Rao A, Ziegler Y, McLeod I, Yates J, Nardulli A. Thioredoxin and thioredoxin reductase influence estrogen receptor alpha-mediated gene expression in human breast cancer cells. J Mol Endocrinol. 2009;43:251-61 pubmed publisher
Massinen S, Tammimies K, Tapia Paez I, Matsson H, Hokkanen M, Söderberg O, et al. Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia. Hum Mol Genet. 2009;18:2802-12 pubmed publisher
Kita K, Jin Y, Sun Z, Chen S, Sumiya Y, Hongo T, et al. Increase in the levels of chaperone proteins by exposure to beta-estradiol, bisphenol A and 4-methoxyphenol in human cells transfected with estrogen receptor alpha cDNA. Toxicol In Vitro. 2009;23:728-35 pubmed publisher
Rokavec M, Schroth W, Amaral S, Fritz P, Antoniadou L, Glavac D, et al. A polymorphism in the TC21 promoter associates with an unfavorable tamoxifen treatment outcome in breast cancer. Cancer Res. 2008;68:9799-808 pubmed publisher
Schultz Norton J, Ziegler Y, Likhite V, Yates J, Nardulli A. Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor alpha. BMC Mol Biol. 2008;9:97 pubmed publisher
Han Y, Feng H, Sandlow J, Haines C. Comparing expression of progesterone and estrogen receptors in testicular tissue from men with obstructive and nonobstructive azoospermia. J Androl. 2009;30:127-33 pubmed publisher
Nagayama K, Sasaki S, Matsushita A, Ohba K, Iwaki H, Matsunaga H, et al. Inhibition of GATA2-dependent transactivation of the TSHbeta gene by ligand-bound estrogen receptor alpha. J Endocrinol. 2008;199:113-25 pubmed publisher
Creekmore A, Walt K, Schultz Norton J, Ziegler Y, McLeod I, Yates J, et al. The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expression. Mol Cell Endocrinol. 2008;291:79-86 pubmed publisher
Keimling M, Kaur J, Bagadi S, Kreienberg R, Wiesmuller L, Ralhan R. A sensitive test for the detection of specific DSB repair defects in primary cells from breast cancer specimens. Int J Cancer. 2008;123:730-6 pubmed publisher
Dillon M, Stafford A, Kelly G, Redmond A, McIlroy M, Crotty T, et al. Cyclooxygenase-2 predicts adverse effects of tamoxifen: a possible mechanism of role for nuclear HER2 in breast cancer patients. Endocr Relat Cancer. 2008;15:745-53 pubmed publisher
Mao C, Patterson N, Cherian M, Aninye I, Zhang C, Montoya J, et al. A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells. J Biol Chem. 2008;283:12819-30 pubmed publisher
Lecomte J, Flament S, Salamone S, Boisbrun M, Mazerbourg S, Chapleur Y, et al. Disruption of ERalpha signalling pathway by PPARgamma agonists: evidences of PPARgamma-independent events in two hormone-dependent breast cancer cell lines. Breast Cancer Res Treat. 2008;112:437-51 pubmed publisher
Ushmorov A, Hogarty M, Liu X, Knauss H, Debatin K, Beltinger C. N-myc augments death and attenuates protective effects of Bcl-2 in trophically stressed neuroblastoma cells. Oncogene. 2008;27:3424-34 pubmed publisher
Henning K, Heering J, Schwanbeck R, Schroeder T, Helmbold H, Schafer H, et al. Notch1 activation reduces proliferation in the multipotent hematopoietic progenitor cell line FDCP-mix through a p53-dependent pathway but Notch1 effects on myeloid and erythroid differentiation are independent of p53. Cell Death Differ. 2008;15:398-407 pubmed
Curtis C, Likhite V, McLeod I, Yates J, Nardulli A. Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor alpha alters estrogen-responsive gene expression. Cancer Res. 2007;67:10600-7 pubmed
Cho M, Lee M, Nam K, Chung W, Park C, Lee J, et al. Expression and role of estrogen receptor alpha and beta in medullary thyroid carcinoma: different roles in cancer growth and apoptosis. J Endocrinol. 2007;195:255-63 pubmed
El Marzouk S, Schultz Norton J, Likhite V, McLeod I, Yates J, Nardulli A. Rho GDP dissociation inhibitor alpha interacts with estrogen receptor alpha and influences estrogen responsiveness. J Mol Endocrinol. 2007;39:249-59 pubmed
Lee G, Choi K, Han H, Jeung E. The classical and a non-classical pathways associated with NF-kappaB are involved in estrogen-mediated regulation of calbindin-D9k gene in rat pituitary cells. Mol Cell Endocrinol. 2007;277:42-50 pubmed
Naughton C, MacLeod K, Kuske B, Clarke R, Cameron D, Langdon S. Progressive loss of estrogen receptor alpha cofactor recruitment in endocrine resistance. Mol Endocrinol. 2007;21:2615-26 pubmed
Schultz Norton J, Gabisi V, Ziegler Y, McLeod I, Yates J, Nardulli A. Interaction of estrogen receptor alpha with proliferating cell nuclear antigen. Nucleic Acids Res. 2007;35:5028-38 pubmed
Schultz Norton J, Walt K, Ziegler Y, McLeod I, Yates J, Raetzman L, et al. The deoxyribonucleic acid repair protein flap endonuclease-1 modulates estrogen-responsive gene expression. Mol Endocrinol. 2007;21:1569-80 pubmed
Oviedo P, Hermenegildo C, Tarín J, Cano A. Raloxifene increases proliferation of human endothelial cells in association with increased gene expression of cyclins A and B1. Fertil Steril. 2007;88:326-32 pubmed
Creekmore A, Ziegler Y, Bonéy J, Nardulli A. Estrogen receptor alpha regulates expression of the breast cancer 1 associated ring domain 1 (BARD1) gene through intronic DNA sequence. Mol Cell Endocrinol. 2007;267:106-15 pubmed
Hanifi Moghaddam P, Sijmons B, Ott M, van Ijcken W, Nowzari D, Kuhne E, et al. The hormone replacement therapy drug tibolone acts very similar to medroxyprogesterone acetate in an estrogen-and progesterone-responsive endometrial cancer cell line. J Mol Endocrinol. 2006;37:405-13 pubmed
Mc Ilroy M, Fleming F, Buggy Y, Hill A, Young L. Tamoxifen-induced ER-alpha-SRC-3 interaction in HER2 positive human breast cancer; a possible mechanism for ER isoform specific recurrence. Endocr Relat Cancer. 2006;13:1135-45 pubmed
Kuske B, Naughton C, Moore K, MacLeod K, Miller W, Clarke R, et al. Endocrine therapy resistance can be associated with high estrogen receptor alpha (ERalpha) expression and reduced ERalpha phosphorylation in breast cancer models. Endocr Relat Cancer. 2006;13:1121-33 pubmed
Zhou D, Ye J, Li Y, Lui K, Chen S. The molecular basis of the interaction between the proline-rich SH3-binding motif of PNRC and estrogen receptor alpha. Nucleic Acids Res. 2006;34:5974-86 pubmed
Berensztein E, Baquedano M, Gonzalez C, Saraco N, Rodriguez J, Ponzio R, et al. Expression of aromatase, estrogen receptor alpha and beta, androgen receptor, and cytochrome P-450scc in the human early prepubertal testis. Pediatr Res. 2006;60:740-4 pubmed
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product information
Product Name :
ERalpha (F-10) Antibody
Gene Name :
ESR1
Size :
200 µg/ml
Catalog Number :
sc-8002
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
ERalpha
reactive species  :
human
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
C-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA