product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PTEN (A2B1) AC
catalog :
sc-7974 AC
quantity :
500 µg/ml, 25% ag
price :
416 USD
clonality :
monoclonal
host :
mouse
conjugate :
agarose
clone name :
A2b1
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 7
Song C, Liu B, Shi Y, Liu N, Yan Y, Zhang J, et al. MicroRNA-130a alleviates human coronary artery endothelial cell injury and inflammatory responses by targeting PTEN via activating PI3K/Akt/eNOS signaling pathway. Oncotarget. 2016;7:71922-71936 pubmed publisher
  • western blot; human; 1:1000; fig s7
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  • western blot; human; fig 4D
Georgescu M, Gagea M, Cote G. NHERF1/EBP50 Suppresses Wnt-?-Catenin Pathway-Driven Intestinal Neoplasia. Neoplasia. 2016;18:512-23 pubmed publisher
  • western blot; human; fig 5b
Kemper K, Krijgsman O, Kong X, Cornelissen Steijger P, Shahrabi A, Weeber F, et al. BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts. Cell Rep. 2016;16:263-277 pubmed publisher
  • western blot; human; fig 2a
Hendrayani S, Al Harbi B, Al Ansari M, Silva G, Aboussekhra A. The inflammatory/cancer-related IL-6/STAT3/NF-?B positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts. Oncotarget. 2016;7:41974-41985 pubmed publisher
  • western blot; mouse; fig 2
Balbas M, Burgess M, Murali R, Wongvipat J, Skaggs B, Mundel P, et al. MAGI-2 scaffold protein is critical for kidney barrier function. Proc Natl Acad Sci U S A. 2014;111:14876-81 pubmed publisher
Chen Z, Jiang H, Xu W, Li X, Dempsey D, Zhang X, et al. A Tunable Brake for HECT Ubiquitin Ligases. Mol Cell. 2017;66:345-357.e6 pubmed publisher
Grande V, Manassero G, Vercelli A. Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy. PLoS ONE. 2014;9:e114554 pubmed publisher
Pérez Sieira S, Martinez G, Porteiro B, Lopez M, Vidal A, Nogueiras R, et al. Female Nur77-deficient mice show increased susceptibility to diet-induced obesity. PLoS ONE. 2013;8:e53836 pubmed publisher
Singh G, Odriozola L, Guan H, Kennedy C, Chan A. Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line. BMC Cancer. 2011;11:490 pubmed publisher
Molina J, Agarwal N, Morales F, Hayashi Y, Aldape K, Cote G, et al. PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma. Oncogene. 2012;31:1264-74 pubmed publisher
Dong S, Corre B, Foulon E, Dufour E, Veillette A, Acuto O, et al. T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. J Exp Med. 2006;203:2509-18 pubmed
product information
Catalog Number :
sc-7974 AC
Product Name :
PTEN (A2B1) AC
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
agarose
Clone Name :
A2B1
Isotype :
IgG1
Size :
500 µg/ml, 25% ag
List Price :
416 USD
Immunogen :
PTEN
Specificity :
mouse, rat, human
Uses :
IP
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA