Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; 1:1000; fig 7
| Morris C, Stanton M, Manthey K, Oh K, Wagner K. A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death. PLoS ONE. 2012;7:e34308 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 1c
| Xie F, Zhou X, Su P, Li H, Tu Y, Du J, et al. Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling. Nat Commun. 2022;13:4461 pubmed publisher
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- western blot; mouse; 1:200; loading ...; fig 1a
| Cheng Z, Naga Srikanth Garikipati V, Truongcao M, CIMINI M, Huang G, Wang C, et al. Serum-Derived Small Extracellular Vesicles From Diabetic Mice Impair Angiogenic Property of Microvascular Endothelial Cells: Role of EZH2. J Am Heart Assoc. 2021;10:e019755 pubmed publisher
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- immunocytochemistry; mouse; 1:100; loading ...; fig 7d
| Little J, McNeely K, Michel N, Bott C, Lettieri K, Hecht M, et al. Loss of Coiled-Coil Protein Cep55 Impairs Neural Stem Cell Abscission and Results in p53-Dependent Apoptosis in Developing Cortex. J Neurosci. 2021;41:3344-3365 pubmed publisher
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- western blot; human; loading ...; fig 1a
| Cordonnier M, Nardin C, Chanteloup G, Derangère V, Algros M, Arnould L, et al. Tracking the evolution of circulating exosomal-PD-L1 to monitor melanoma patients. J Extracell Vesicles. 2020;9:1710899 pubmed publisher
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- western blot; human; loading ...; fig 1b
| Wan Z, Zhao L, Lu F, Gao X, Dong Y, Zhao Y, et al. Mononuclear phagocyte system blockade improves therapeutic exosome delivery to the myocardium. Theranostics. 2020;10:218-230 pubmed publisher
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- western blot; human; 1:100; loading ...; fig 2e
| Geeurickx E, Tulkens J, Dhondt B, Van Deun J, Lippens L, Vergauwen G, et al. The generation and use of recombinant extracellular vesicles as biological reference material. Nat Commun. 2019;10:3288 pubmed publisher
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- western blot; human; 1:200; loading ...; fig 2f, 5c
| Javidi Sharifi N, Martinez J, English I, Joshi S, Scopim Ribeiro R, Viola S, et al. FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells. elife. 2019;8: pubmed publisher
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- western blot; human; loading ...; fig s8
| Skowyra M, Schlesinger P, Naismith T, Hanson P. Triggered recruitment of ESCRT machinery promotes endolysosomal repair. Science. 2018;360: pubmed publisher
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- western blot; mouse; loading ...; fig 2i
| Wan Y, Wang L, Zhu C, Zheng Q, Wang G, Tong J, et al. Aptamer-Conjugated Extracellular Nanovesicles for Targeted Drug Delivery. Cancer Res. 2018;78:798-808 pubmed publisher
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- western blot; human; 1:200; loading ...; fig 1g
| Mrowczynski O, Madhankumar A, Slagle Webb B, Lee S, Zacharia B, Connor J. HFE genotype affects exosome phenotype in cancer. Biochim Biophys Acta Gen Subj. 2017;1861:1921-1928 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig s2a
| Bednash J, Weathington N, Londino J, Rojas M, Gulick D, Fort R, et al. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017;8:15203 pubmed publisher
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- western blot; human; fig 7e
| VALLABHAJOSYULA P, Korutla L, Habertheuer A, Yu M, Rostami S, Yuan C, et al. Tissue-specific exosome biomarkers for noninvasively monitoring immunologic rejection of transplanted tissue. J Clin Invest. 2017;127:1375-1391 pubmed publisher
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- western blot; human; 1:200; fig 2i
| Chiang C, Flint M, Lin J, Spiropoulou C. Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells. PLoS ONE. 2016;11:e0164768 pubmed publisher
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- western blot; human; loading ...; fig 1e
| Puhka M, Nordberg M, Valkonen S, Rannikko A, Kallioniemi O, Siljander P, et al. KeepEX, a simple dilution protocol for improving extracellular vesicle yields from urine. Eur J Pharm Sci. 2017;98:30-39 pubmed publisher
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- immunoprecipitation; human; loading ...; fig 5a
- immunocytochemistry; human; loading ...; fig 3a
- western blot; human; loading ...; fig 1a
| Kumar B, Dutta D, Iqbal J, Ansari M, Roy A, Chikoti L, et al. ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus. PLoS Pathog. 2016;12:e1005960 pubmed publisher
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- western blot; mouse; loading ...; fig 1b
| Dinkins M, Enasko J, Hernandez C, Wang G, Kong J, Helwa I, et al. Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse. J Neurosci. 2016;36:8653-67 pubmed publisher
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- immunoprecipitation; mouse; loading ...; fig 6d
- western blot; mouse; loading ...; fig 5a
- western blot; human; loading ...; fig 2c
| Diaz Hidalgo L, Altuntas S, Rossin F, D Eletto M, Marsella C, Farrace M, et al. Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions. Biochim Biophys Acta. 2016;1863:2084-92 pubmed publisher
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- western blot; human; fig 1
| Rider M, Hurwitz S, Meckes D. ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles. Sci Rep. 2016;6:23978 pubmed publisher
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- western blot; human; fig 1
| Conigliaro A, Costa V, Lo Dico A, Saieva L, Buccheri S, Dieli F, et al. CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA. Mol Cancer. 2015;14:155 pubmed publisher
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- western blot; human; 1:1000; fig 1
| Li H, Han L, Yang Z, Huang W, Zhang X, Gu Y, et al. Differential Proteomic Analysis of Syncytiotrophoblast Extracellular Vesicles from Early-Onset Severe Preeclampsia, using 8-Plex iTRAQ Labeling Coupled with 2D Nano LC-MS/MS. Cell Physiol Biochem. 2015;36:1116-30 pubmed publisher
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- western blot; human; fig s3
| Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, et al. Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. J Mol Cell Biol. 2015;7:143-53 pubmed publisher
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- western blot; human; 1:1000
| Van Deun J, Mestdagh P, Sormunen R, Cocquyt V, Vermaelen K, Vandesompele J, et al. The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling. J Extracell Vesicles. 2014;3: pubmed publisher
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- western blot; human; fig 1
| Cypryk W, Ohman T, Eskelinen E, Matikainen S, Nyman T. Quantitative proteomics of extracellular vesicles released from human monocyte-derived macrophages upon ?-glucan stimulation. J Proteome Res. 2014;13:2468-77 pubmed publisher
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- immunocytochemistry; African green monkey; loading ...; fig s1a
| Van Engelenburg S, Shtengel G, Sengupta P, Waki K, Jarnik M, Ablan S, et al. Distribution of ESCRT machinery at HIV assembly sites reveals virus scaffolding of ESCRT subunits. Science. 2014;343:653-6 pubmed publisher
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| Wu C, Li Z, Feng G, Wang L, Xie J, Jin Y, et al. Tumor suppressing role of serum-derived exosomal microRNA-15a in osteosarcoma cells through the GATA binding protein 2/murine double minute 2 axis and the p53 signaling pathway. Bioengineered. 2021;12:8378-8395 pubmed publisher
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| Coudert L, Osseni A, Gangloff Y, Schaeffer L, Leblanc P. The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways. BMC Biol. 2021;19:153 pubmed publisher
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| Martínez Greene J, Hernández Ortega K, Quiroz Baez R, Resendis Antonio O, Pichardo Casas I, Sinclair D, et al. Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. J Extracell Vesicles. 2021;10:e12087 pubmed publisher
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| Hettich B, Ben Yehuda Greenwald M, Werner S, Leroux J. Exosomes for Wound Healing: Purification Optimization and Identification of Bioactive Components. Adv Sci (Weinh). 2020;7:2002596 pubmed publisher
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| Lauritzen I, Bécot A, Bourgeois A, Pardossi Piquard R, Biferi M, Barkats M, et al. Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models. Transl Neurodegener. 2019;8:35 pubmed publisher
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| Karasmanis E, Hwang D, Nakos K, Bowen J, Angelis D, Spiliotis E. A Septin Double Ring Controls the Spatiotemporal Organization of the ESCRT Machinery in Cytokinetic Abscission. Curr Biol. 2019;: pubmed publisher
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| Fulzele S, Mendhe B, Khayrullin A, Johnson M, Kaiser H, Liu Y, et al. Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells. Aging (Albany NY). 2019;11:1791-1803 pubmed publisher
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| Nehls J, Businger R, Hoffmann M, Brinkmann C, Fehrenbacher B, Schaller M, et al. Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner. Cell Rep. 2019;26:1841-1853.e6 pubmed publisher
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| Kim J, Afshari A, Sengupta R, Sebastiano V, Gupta A, Kim Y, et al. Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. elife. 2018;7: pubmed publisher
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| Myles I, Anderson E, Earland N, Zarember K, Sastalla I, Williams K, et al. TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome. J Clin Invest. 2018;128:3595-3604 pubmed publisher
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| Abdulrahman B, Abdelaziz D, Schatzl H. Autophagy regulates exosomal release of prions in neuronal cells. J Biol Chem. 2018;293:8956-8968 pubmed publisher
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| Zhang Y, Kim M, Jia B, Yan J, Zuniga Hertz J, Han C, et al. Hypothalamic stem cells control ageing speed partly through exosomal miRNAs. Nature. 2017;548:52-57 pubmed publisher
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| Mehta A, Cordero J, Dobersch S, Romero Olmedo A, Savai R, Bodner J, et al. Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate. EMBO Mol Med. 2016;8:1380-1389 pubmed publisher
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| Song X, Ding Y, Liu G, Yang X, Zhao R, Zhang Y, et al. Cancer Cell-derived Exosomes Induce Mitogen-activated Protein Kinase-dependent Monocyte Survival by Transport of Functional Receptor Tyrosine Kinases. J Biol Chem. 2016;291:8453-64 pubmed publisher
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| Lesnik J, ANTES T, Kim J, Griner E, Pedro L. Registered report: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. elife. 2016;5:e07383 pubmed publisher
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| Scheffer L, Sreetama S, Sharma N, Medikayala S, Brown K, Defour A, et al. Mechanism of Ca²âº-triggered ESCRT assembly and regulation of cell membrane repair. Nat Commun. 2014;5:5646 pubmed publisher
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| Faresse N, Debonneville A, Staub O. USP2-45 represses aldosterone mediated responses by decreasing mineralocorticoid receptor availability. Cell Physiol Biochem. 2013;31:462-72 pubmed publisher
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| Huang S, Wu C, Chang Y, Kwon Chung K, Brown R, Jong A. Cryptococcus neoformans-derived microvesicles enhance the pathogenesis of fungal brain infection. PLoS ONE. 2012;7:e48570 pubmed publisher
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| Lee H, Koo B, Kim Y, Jeon O, Kim D. Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes. FASEB J. 2012;26:3084-95 pubmed publisher
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| Ruiss R, Jochum S, Mocikat R, Hammerschmidt W, Zeidler R. EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells--a new option for the treatment of B-CLL. PLoS ONE. 2011;6:e25294 pubmed publisher
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| Huang S, Wu C, Jiang S, Bahner I, Lossinsky A, Jong A. HIV-1 gp41 ectodomain enhances Cryptococcus neoformans binding to human brain microvascular endothelial cells via gp41 core-induced membrane activities. Biochem J. 2011;438:457-66 pubmed publisher
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| Lenassi M, Cagney G, Liao M, Vaupotic T, Bartholomeeusen K, Cheng Y, et al. HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Traffic. 2010;11:110-22 pubmed publisher
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| Jong A, Wu C, Shackleford G, Kwon Chung K, Chang Y, Chen H, et al. Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells. Cell Microbiol. 2008;10:1313-26 pubmed publisher
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| Ellenberg P, Linero F, Scolaro L. Superinfection exclusion in BHK-21 cells persistently infected with Junín virus. J Gen Virol. 2007;88:2730-9 pubmed
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| Hanyaloglu A, McCullagh E, von Zastrow M. Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling. EMBO J. 2005;24:2265-83 pubmed
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