product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Smad1/2/3 (H-2) Antibody
catalog :
sc-7960
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-2
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...
Chan D, Hui W, Wang J, Yung M, Hui L, Qin Y, et al. DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling. Oncogene. 2017;36:1404-1416 pubmed publisher
Narayana Y, Gadgil C, Mote R, Rajan R, Subramanyam D. Clathrin-Mediated Endocytosis Regulates a Balance between Opposing Signals to Maintain the Pluripotent State of Embryonic Stem Cells. Stem Cell Reports. 2019;12:152-164 pubmed publisher
Zöller T, Schneider A, Kleimeyer C, Masuda T, Potru P, Pfeifer D, et al. Silencing of TGFβ signalling in microglia results in impaired homeostasis. Nat Commun. 2018;9:4011 pubmed publisher
Li N, Zhang M, Drummen G, Zhao Y, Tan Y, Luo S, et al. Sika Deer Antler Collagen Type I-Accelerated Osteogenesis in Bone Marrow Mesenchymal Stem Cells via the Smad Pathway. Evid Based Complement Alternat Med. 2016;2016:2109204 pubmed publisher
Wang D, Dai C, Li Y, Liu Y. Canonical Wnt/?-catenin signaling mediates transforming growth factor-?1-driven podocyte injury and proteinuria. Kidney Int. 2011;80:1159-1169 pubmed publisher
Zi Z, Feng Z, Chapnick D, Dahl M, Deng D, Klipp E, et al. Quantitative analysis of transient and sustained transforming growth factor-? signaling dynamics. Mol Syst Biol. 2011;7:492 pubmed publisher
Erbuyun K, Tok D, Vatansever S, Ok G, Turkoz E, Aydede H, et al. Levosimendan up-regulates transforming growth factor-beta and smad signaling in the aorta in the early stage of sepsis. Ulus Travma Acil Cerrahi Derg. 2010;16:293-9 pubmed
Kang Y, Li Y, Dai C, Kiss L, Wu C, Liu Y. Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria. Kidney Int. 2010;78:363-73 pubmed publisher
Luciakova K, Kollarovic G, Barath P, Nelson B. Growth-dependent repression of human adenine nucleotide translocator-2 (ANT2) transcription: evidence for the participation of Smad and Sp family proteins in the NF1-dependent repressor complex. Biochem J. 2008;412:123-30 pubmed publisher
Gohla G, Krieglstein K, Spittau B. Tieg3/Klf11 induces apoptosis in OLI-neu cells and enhances the TGF-beta signaling pathway by transcriptional repression of Smad7. J Cell Biochem. 2008;104:850-61 pubmed publisher
Pannu J, Nakerakanti S, Smith E, Ten Dijke P, Trojanowska M. Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways. J Biol Chem. 2007;282:10405-13 pubmed
Rees J, Onwuegbusi B, Save V, Alderson D, Fitzgerald R. In vivo and in vitro evidence for transforming growth factor-beta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma. Cancer Res. 2006;66:9583-90 pubmed
Seay U, Sedding D, Krick S, Hecker M, Seeger W, Eickelberg O. Transforming growth factor-beta-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent. J Pharmacol Exp Ther. 2005;315:1005-12 pubmed
Duenker N, Valenciano A, Franke A, Hernandez Sanchez C, Dressel R, Behrendt M, et al. Balance of pro-apoptotic transforming growth factor-beta and anti-apoptotic insulin effects in the control of cell death in the postnatal mouse retina. Eur J Neurosci. 2005;22:28-38 pubmed
product information
Product Name :
Smad1/2/3 (H-2) Antibody
Gene Name :
SMAD1, SMAD2, SMAD3
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7960
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Smad1/2/3
reactive species  :
m, r, h, mink
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
1-465 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA