product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Skp2 p45 (A-2) Antibody
catalog :
sc-74477
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-2
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2e
Nagashima K, Fukushima H, Shimizu K, Yamada A, Hidaka M, Hasumi H, et al. Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression. Oncotarget. 2017;8:9947-9960 pubmed publisher
Vosper J, Masuccio A, Kullmann M, Ploner C, Geley S, Hengst L. Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation. Oncotarget. 2015;6:2889-902 pubmed
Tsai Y, Lai C, Lai C, Chang K, Wu K, Tseng S, et al. The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget. 2014;5:6425-36 pubmed
Cheng H, Meng J, Wang G, Meng Y, Li Y, Wei D, et al. Skp2 regulates subcellular localization of PPAR? by MEK signaling pathways in human breast cancer. Int J Mol Sci. 2013;14:16554-69 pubmed publisher
Kullmann M, Grubbauer C, Goetsch K, Jakel H, Podmirseg S, Trockenbacher A, et al. The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells. Cell Cycle. 2013;12:2625-35 pubmed publisher
Meng J, Ding Y, Shen A, Yan M, He F, Ji H, et al. Overexpression of PPAR? can down-regulate Skp2 expression in MDA-MB-231 breast tumor cells. Mol Cell Biochem. 2010;345:171-80 pubmed publisher
Li X, Cai L, Chen H, Zhang Q, Zhang S, Wang Y, et al. Inhibitor of growth 4 induces growth suppression and apoptosis in glioma U87MG. Pathobiology. 2009;76:181-92 pubmed publisher
product information
Catalog Number :
sc-74477
Product Name :
Skp2 p45 (A-2) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
A-2
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Skp2 p45
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA