product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
IRF-7 (G-8) Antibody
catalog :
sc-74472
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G-8
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3c
Maarifi G, Smith N, Maillet S, Moncorgé O, Chamontin C, Edouard J, et al. TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells. Sci Adv. 2019;5:eaax3511 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 8b
Bao M, Wang Y, Liu Y, Shi P, Lu H, Sha W, et al. NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells. J Exp Med. 2016;213:2383-2398 pubmed
Shigesaka M, Ito T, Inaba M, Imai K, Yamanaka H, Azuma Y, et al. Mycophenolic acid, the active form of mycophenolate mofetil, interferes with IRF7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells. Arthritis Res Ther. 2020;22:264 pubmed publisher
Sweeney S. Targeting interferon regulatory factors to inhibit activation of the type I IFN response: implications for treatment of autoimmune disorders. Cell Immunol. 2011;271:342-9 pubmed publisher
Sweeney S. Hematopoietic stem cell transplant for systemic lupus erythematosus: Interferon regulatory factor 7 activation correlates with the IFN signature and recurrent disease. Lupus. 2011;20:975-80 pubmed publisher
Sweeney S, Kimbler T, Firestein G. Synoviocyte innate immune responses: II. Pivotal role of IFN regulatory factor 3. J Immunol. 2010;184:7162-8 pubmed publisher
product information
Catalog Number :
sc-74472
Product Name :
IRF-7 (G-8) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
G-8
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
IRF-7
Specificity :
human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA