product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
NFkappaB p52 (C-5) Antibody
catalog :
sc-7386
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-5
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, other
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig e6a
Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed publisher
  • western blot; mouse; loading ...; fig 4d
Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, et al. Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus. Nat Commun. 2018;9:1136 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human
Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed publisher
Yang H, Kim J, Kim S, Choe C, Jang Y. Pro-IL-16 is associated with MHC class II-mediated negative regulation of mouse resting B cell activation through MAP kinases, NF-?B and Skp2-dependent p27kip regulation. Scand J Immunol. 2013;77:177-86 pubmed publisher
Yu M, Chen Y, He Y, Podd A, Fu G, Wright J, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-?B activation and survival of anergic B cells. J Immunol. 2012;189:5185-93 pubmed publisher
Sheng L, Zhou Y, Chen Z, Ren D, Cho K, Jiang L, et al. NF-?B–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action. Nat Med. 2012;18:943-9 pubmed publisher
Dimitrakopoulos F, Antonacopoulou A, Kottorou A, Vlotinou H, Panagopoulos N, Dougenis D, et al. NSCLC and the alternative pathway of NF-?B: uncovering an unknown relation. Virchows Arch. 2012;460:515-23 pubmed publisher
Takeiri M, Horie K, Takahashi D, Watanabe M, Horie R, Simizu S, et al. Involvement of DNA binding domain in the cellular stability and importin affinity of NF-?B component RelB. Org Biomol Chem. 2012;10:3053-9 pubmed publisher
Schluter A, Espinosa L, Fourcade S, Galino J, Lopez E, Ilieva E, et al. Functional genomic analysis unravels a metabolic-inflammatory interplay in adrenoleukodystrophy. Hum Mol Genet. 2012;21:1062-77 pubmed publisher
Yang C, Atkinson S, Vilella F, Lloret M, Armstrong L, Mann D, et al. Opposing putative roles for canonical and noncanonical NF?B signaling on the survival, proliferation, and differentiation potential of human embryonic stem cells. Stem Cells. 2010;28:1970-80 pubmed publisher
Xie Z, Chng W, Tay K, Liu S, Zhou J, Chen C. Therapeutic potential of antisense oligodeoxynucleotides in downregulating p53 oncogenic mutations in cancers. Biotechnol Lett. 2011;33:221-8 pubmed publisher
Rajanbabu V, Pan C, Lee S, Lin W, Lin C, Li C, et al. Tilapia hepcidin 2-3 peptide modulates lipopolysaccharide-induced cytokines and inhibits tumor necrosis factor-alpha through cyclooxygenase-2 and phosphodiesterase 4D. J Biol Chem. 2010;285:30577-86 pubmed publisher
O Neil B, Funkhouser W, Calvo B, Meyers M, Kim H, Goldberg R, et al. Nuclear factor ?-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy. Int J Radiat Oncol Biol Phys. 2011;80:705-11 pubmed publisher
Saitoh Y, Martínez Bruyn V, Uota S, Hasegawa A, Yamamoto N, Imoto I, et al. Overexpression of NF-?B inducing kinase underlies constitutive NF-?B activation in lung cancer cells. Lung Cancer. 2010;70:263-70 pubmed publisher
Yang H, Kim J, Lee K, Jang Y. Rac/ROS-related protein kinase C and phosphatidylinositol-3-kinase signaling are involved in a negative regulating cascade in B cell activation by antibody-mediated cross-linking of MHC class II molecules. Mol Immunol. 2010;47:706-12 pubmed publisher
Honma K, Tsuzuki S, Nakagawa M, Tagawa H, Nakamura S, Morishima Y, et al. TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood. 2009;114:2467-75 pubmed publisher
Castro I, Wright J, Damdinsuren B, Hoek K, Carlesso G, Shinners N, et al. B cell receptor-mediated sustained c-Rel activation facilitates late transitional B cell survival through control of B cell activating factor receptor and NF-kappaB2. J Immunol. 2009;182:7729-37 pubmed publisher
Olsnes A, Ersvaer E, Ryningen A, Paulsen K, Hampson P, Lord J, et al. The protein kinase C agonist PEP005 increases NF-kappaB expression, induces differentiation and increases constitutive chemokine release by primary acute myeloid leukaemia cells. Br J Haematol. 2009;145:761-74 pubmed publisher
Souvannavong V, Saidji N, Chaby R. Lipopolysaccharide from Salmonella enterica activates NF-kappaB through both classical and alternative pathways in primary B Lymphocytes. Infect Immun. 2007;75:4998-5003 pubmed
Merling R, Chen C, Hong S, Zhang L, Liu M, Kuo Y, et al. HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex. Retrovirology. 2007;4:35 pubmed
Moore F, Buonocore S, Aksoy E, Ouled Haddou N, Goriely S, Lazarova E, et al. An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha. J Immunol. 2007;178:1301-11 pubmed
Fernández Majada V, Aguilera C, Villanueva A, Vilardell F, Robert Moreno A, Aytes A, et al. Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer. Proc Natl Acad Sci U S A. 2007;104:276-81 pubmed
Yang H, Kim J, Chung G, Lee J, Jang Y. Cross-linking of MHC class II molecules interferes with phorbol 12,13-dibutyrate-induced differentiation of resting B cells by inhibiting Rac-associated ROS-dependent ERK/p38 MAP kinase pathways leading to NF-kappaB activation. Mol Immunol. 2007;44:1577-86 pubmed
Liu H, Zang C, Fenner M, Liu D, Possinger K, Koeffler H, et al. Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18. Blood. 2006;107:3683-92 pubmed
Scian M, Stagliano K, Anderson M, Hassan S, Bowman M, Miles M, et al. Tumor-derived p53 mutants induce NF-kappaB2 gene expression. Mol Cell Biol. 2005;25:10097-110 pubmed
product information
Product Name :
NFkappaB p52 (C-5) Antibody
Gene Name :
NFKB2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7386
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
NFkappaB p52
reactive species  :
m, r, h
Application :
WB, IP, IF, FCM
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA