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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
vinculin (7F9) Antibody
catalog :
sc-73614
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7F9
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation
citations: 60
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 6c
Hendley A, Rao A, Leonhardt L, Ashe S, Smith J, Giacometti S, et al. Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. elife. 2021;10: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4h
Citron F, Segatto I, Musco L, Pellarin I, Rampioni Vinciguerra G, Franchin G, et al. miR-9 modulates and predicts the response to radiotherapy and EGFR inhibition in HNSCC. EMBO Mol Med. 2021;13:e12872 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a
Wepler M, Preuss J, Merz T, Hartmann C, Wachter U, McCook O, et al. Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction. Front Immunol. 2019;10:3152 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2e, 5b
Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed publisher
  • western blot; human; loading ...; fig 3b
Zhou N, Gutierrez Uzquiza A, Zheng X, Chang R, Vogl D, Garfall A, et al. RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019;: pubmed publisher
  • western blot; human; fig 6a
Schnack L, Sohrabi Y, Lagache S, Kahles F, Bruemmer D, Waltenberger J, et al. Mechanisms of Trained Innate Immunity in oxLDL Primed Human Coronary Smooth Muscle Cells. Front Immunol. 2019;10:13 pubmed publisher
  • western blot; human; 1:1000; fig s3
Fotouhi O, Kjellin H, Larsson C, Hashemi J, Barriuso J, Juhlin C, et al. Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors. J Clin Endocrinol Metab. 2016;101:3616-3627 pubmed
  • immunocytochemistry; human; 1:300; loading ...; fig 3a
Du P, Suhaeri M, Subbiah R, Van S, Park J, Kim S, et al. Elasticity Modulation of Fibroblast-Derived Matrix for Endothelial Cell Vascular Morphogenesis and Mesenchymal Stem Cell Differentiation. Tissue Eng Part A. 2016;22:415-26 pubmed publisher
  • western blot; human; fig s2
Cataldo A, Cheung D, Balsari A, Tagliabue E, Coppola V, Iorio M, et al. miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. Oncotarget. 2016;7:786-97 pubmed publisher
  • western blot; mouse; 1:5000; fig 5
Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, et al. A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis. Nat Commun. 2015;6:8501 pubmed publisher
  • immunocytochemistry; mouse
Suhaeri M, Subbiah R, Van S, Du P, Kim I, Lee K, et al. Cardiomyoblast (h9c2) differentiation on tunable extracellular matrix microenvironment. Tissue Eng Part A. 2015;21:1940-51 pubmed publisher
  • western blot; mouse
Li T, Lu H, Shen C, Lahiri S, Wason M, Mukherjee D, et al. Identification of epithelial stromal interaction 1 as a novel effector downstream of Krüppel-like factor 8 in breast cancer invasion and metastasis. Oncogene. 2014;33:4746-55 pubmed publisher
Papalazarou V, Newman A, Huerta Uribe A, Legrave N, Falcone M, Zhang T, et al. Phenotypic profiling of solute carriers characterizes serine transport in cancer. Nat Metab. 2023;5:2148-2168 pubmed publisher
Pinto L, Pailas A, Bondarchenko M, Sharma A, Neumann K, Rizzo A, et al. DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks. Nucleic Acids Res. 2023;: pubmed publisher
Shatat M, Gauthier B, Yoon S, Yuan E, Yang P, Narla G, et al. Mistletoe lectin inhibits growth of Myc-amplified small-cell lung cancer. Cancer Med. 2022;: pubmed publisher
Yang L, Fye M, Yang B, Tang Z, Zhang Y, Haigh S, et al. Genome-wide CRISPR screen identified a role for commander complex mediated ITGB1 recycling in basal insulin secretion. Mol Metab. 2022;63:101541 pubmed publisher
Tsai J, Cejas P, Wang D, Patel S, Wu D, Arounleut P, et al. FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits. Cancer Res. 2022;: pubmed publisher
Cai W, Nguyen M, Wilski N, Purwin T, Vernon M, Tiago M, et al. A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma. Cancer Res. 2022;: pubmed publisher
Boudreault S, Durand M, Martineau C, Perreault J, Lemay G, Bisaillon M. Reovirus μ2 protein modulates host cell alternative splicing by reducing protein levels of U5 snRNP core components. Nucleic Acids Res. 2022;50:5263-5281 pubmed publisher
Alborzinia H, Flórez A, Kreth S, Brückner L, Yildiz U, Gartlgruber M, et al. MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis. Nat Cancer. 2022;3:471-485 pubmed publisher
Nelde A, Fl xf6 totto L, J xfc rgens L, Szymik L, Hubert E, Bauer J, et al. Upstream open reading frames regulate translation of cancer-associated transcripts and encode HLA-presented immunogenic tumor antigens. Cell Mol Life Sci. 2022;79:171 pubmed publisher
Umansky C, Morellato A, Rieckher M, Scheidegger M, Martinefski M, Fernández G, et al. Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity. Nat Commun. 2022;13:745 pubmed publisher
Zhou J, Dabiri Y, Gama Brambila R, Ghafoory S, Altinbay M, Mehrabi A, et al. pVHL-mediated SMAD3 degradation suppresses TGF-β signaling. J Cell Biol. 2022;221: pubmed publisher
Shimizu K, Gi M, Suzuki S, North B, Watahiki A, Fukumoto S, et al. Interplay between protein acetylation and ubiquitination controls MCL1 protein stability. Cell Rep. 2021;37:109988 pubmed publisher
Hollenbach M, Sonnenberg S, Sommerer I, Lorenz J, Hoffmeister A. Glyoxalase-I Is Upregulated in Acute Cerulein-Induced Pancreatitis: A New Mechanism in Pancreatic Inflammation?. Antioxidants (Basel). 2021;10: pubmed publisher
Solé A, Grossetete S, Heintzé M, Babin L, Zaidi S, Revy P, et al. Unraveling Ewing sarcoma tumorigenesis originating from patient-derived Mesenchymal Stem Cells. Cancer Res. 2021;: pubmed publisher
Kim H, Yim J, Yoo H, Lee S, Oh S, Jung S, et al. EVI1 activates tumor-promoting transcriptional enhancers in pancreatic cancer. NAR Cancer. 2021;3:zcab023 pubmed publisher
Jaiswal A, Truong H, Tran T, Lin T, Casero D, Alberti M, et al. Focused CRISPR-Cas9 genetic screening reveals USO1 as a vulnerability in B-cell acute lymphoblastic leukemia. Sci Rep. 2021;11:13158 pubmed publisher
Zatreanu D, Robinson H, Alkhatib O, Boursier M, Finch H, Geo L, et al. Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nat Commun. 2021;12:3636 pubmed publisher
Timblin G, Tharp K, Ford B, Winchester J, Wang J, Zhu S, et al. Mitohormesis reprogrammes macrophage metabolism to enforce tolerance. Nat Metab. 2021;3:618-635 pubmed publisher
Wei Q, Singh O, Ekinci C, Gill J, Li M, Mamatjan Y, et al. TNFα secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy. Acta Neuropathol Commun. 2021;9:67 pubmed publisher
Brea R, Valdecantos P, Rada P, Alen R, García Monzón C, Bosca L, et al. Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress. Aging (Albany NY). 2021;13:7800-7827 pubmed publisher
Yang W, Lin C, Wu J, Chao P, Chen K, Chen P, et al. The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2. Mol Cancer Res. 2021;19:1005-1014 pubmed publisher
Tajan M, Hennequart M, Cheung E, Zani F, Hock A, Legrave N, et al. Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy. Nat Commun. 2021;12:366 pubmed publisher
Chansel Da Cruz M, Hohl M, Ceppi I, Kermasson L, Maggiorella L, Modesti M, et al. A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans. Cell Rep. 2020;33:108559 pubmed publisher
Holzerland J, F xe9 n xe9 ant L, Banadyga L, H xf6 lper J, Knittler M, Groseth A. BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis. PLoS Pathog. 2020;16:e1008948 pubmed publisher
Boix C, Lopez Font I, Cuchillo Ibanez I, Saez Valero J. Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease. Alzheimers Res Ther. 2020;12:96 pubmed publisher
Cheng X, Haeberle S, Luca Shytaj I, Gama Brambila R, Theobald J, Ghafoory S, et al. NHC-gold compounds mediate immune suppression through induction of AHR-TGFβ1 signalling in vitro and in scurfy mice. Commun Biol. 2020;3:10 pubmed publisher
Cai W, Su L, Liao L, Liu Z, Langbein L, Dulaimi E, et al. PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth. Nat Commun. 2019;10:5800 pubmed publisher
Glazier R, Brockman J, Bartle E, Mattheyses A, Destaing O, Salaita K. DNA mechanotechnology reveals that integrin receptors apply pN forces in podosomes on fluid substrates. Nat Commun. 2019;10:4507 pubmed publisher
Chakravorty S, Yan B, Wang C, Wang L, Quaid J, Lin C, et al. Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host-Virus Interactions. Cancer Res. 2019;79:6010-6023 pubmed publisher
Dabiri Y, Abu El Maaty M, Chan H, Wölker J, Ott I, Wolfl S, et al. p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells. Front Oncol. 2019;9:438 pubmed publisher
Esnault C, Rahmé R, Rice K, Berthier C, Gaillard C, Quentin S, et al. FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias. Blood. 2019;: pubmed publisher
Khan I, Spencer Smith R, O Bryan J. Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo. Oncogene. 2019;38:2984-2993 pubmed publisher
Willis I, Moir R, Hernandez N. Metabolic programming a lean phenotype by deregulation of RNA polymerase III. Proc Natl Acad Sci U S A. 2018;115:12182-12187 pubmed publisher
Chellini L, Caprara V, Spadaro F, Sestito R, Bagnato A, Rosanò L. Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer. Matrix Biol. 2018;: pubmed publisher
Liao L, Liu Z, Langbein L, Cai W, Cho E, Na J, et al. Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer. elife. 2018;7: pubmed publisher
Avolio R, Järvelin A, Mohammed S, Agliarulo I, Condelli V, Zoppoli P, et al. Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Res. 2018;46:12067-12086 pubmed publisher
Tsai M, Chiang M, Tsai D, Yang C, Hou H, Li Y, et al. Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics. Sci Rep. 2018;8:11497 pubmed publisher
Clements K, Thakar T, Nicolae C, Liang X, Wang H, Moldovan G. Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells. Nucleic Acids Res. 2018;46:8898-8907 pubmed publisher
Kwon E, Todorova K, Wang J, Horos R, Lee K, Neel V, et al. The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nat Commun. 2018;9:1734 pubmed publisher
Proietti S, Catizone A, Masiello M, Dinicola S, Fabrizi G, Minini M, et al. Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin through inhibition of ERK phosphorylation. J Pineal Res. 2018;64:e12467 pubmed publisher
Gallagher S, Gunatilake D, Beaumont K, Sharp D, Tiffen J, Heinemann A, et al. HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. Int J Cancer. 2018;142:1926-1937 pubmed publisher
Matsubara T, Kokabu S, Nakatomi C, Kinbara M, Maeda T, Yoshizawa M, et al. The Actin-Binding Protein PPP1r18 Regulates Maturation, Actin Organization, and Bone Resorption Activity of Osteoclasts. Mol Cell Biol. 2018;38: pubmed publisher
Deivendran S, Marzook H, Santhoshkumar T, Kumar R, Pillai M. Metastasis-associated protein 1 is an upstream regulator of DNMT3a and stimulator of insulin-growth factor binding protein-3 in breast cancer. Sci Rep. 2017;7:44225 pubmed publisher
Hoppe Seyler K, Bossler F, Lohrey C, Bulkescher J, Rösl F, Jansen L, et al. Induction of dormancy in hypoxic human papillomavirus-positive cancer cells. Proc Natl Acad Sci U S A. 2017;114:E990-E998 pubmed publisher
Zhang T, Niu X, Liao L, Cho E, Yang H. The contributions of HIF-target genes to tumor growth in RCC. PLoS ONE. 2013;8:e80544 pubmed publisher
Di Luca A, Elia G, Mullen A, Hamill R. Monitoring post mortem changes in porcine muscle through 2-D DIGE proteome analysis of Longissimus muscle exudate. Proteome Sci. 2013;11:9 pubmed publisher
Zhou L, Yang H. The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR. PLoS ONE. 2011;6:e23936 pubmed publisher
Niu X, Zhang T, Liao L, Zhou L, Lindner D, Zhou M, et al. The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C. Oncogene. 2012;31:776-86 pubmed publisher
product information
Catalog Number :
sc-73614
Product Name :
vinculin (7F9) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
7F9
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
vinculin
Specificity :
human, mouse, rat, avian
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA