product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GADD 153 (B-3) Antibody
catalog :
sc-7351
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-3
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 112
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5a
Mogilenko D, Haas J, L homme L, Fleury S, Quemener S, Levavasseur M, et al. Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019;177:1201-1216.e19 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Homma T, Kurahashi T, Lee J, Nabeshima A, Yamada S, Fujii J. Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure. Oxid Med Cell Longev. 2018;2018:2812904 pubmed publisher
  • western blot; mouse; fig 1n
Ersoy B, Maner Smith K, Li Y, Alpertunga I, Cohen D. Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress. J Clin Invest. 2018;128:141-156 pubmed publisher
  • western blot; mouse; 1:500; fig 7a
Pereira R, Tadinada S, Zasadny F, Oliveira K, Pires K, Olvera A, et al. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017;36:2126-2145 pubmed publisher
  • western blot; mouse; fig 1a
Samuel S, Ghosh S, Majeed Y, Arunachalam G, Emara M, Ding H, et al. Metformin represses glucose starvation induced autophagic response in microvascular endothelial cells and promotes cell death. Biochem Pharmacol. 2017;132:118-132 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Xiao F, Zhang J, Zhang C, An W. Hepatic stimulator substance inhibits calcium overflow through the mitochondria-associated membrane compartment during nonalcoholic steatohepatitis. Lab Invest. 2017;97:289-301 pubmed publisher
  • western blot; mouse; 1:400; loading ...; fig 1a
Silva R, Sattlegger E, Castilho B. Perturbations in actin dynamics reconfigure protein complexes that modulate GCN2 activity and promote an eIF2 response. J Cell Sci. 2016;129:4521-4533 pubmed
  • western blot; mouse; 1:1000; fig 5
Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield P, et al. Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia. 2016;59:1513-1523 pubmed publisher
  • western blot; mouse; fig 3c
Fusakio M, Willy J, Wang Y, Mirek E, Al Baghdadi R, Adams C, et al. Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver. Mol Biol Cell. 2016;27:1536-51 pubmed publisher
  • western blot; human; 1:200; fig 5
Hackler L, Ozsvári B, Gyuris M, Sipos P, Fábián G, Molnar E, et al. The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo. PLoS ONE. 2016;11:e0149832 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s1c
Oñate M, Catenaccio A, Martínez G, Armentano D, Parsons G, Kerr B, et al. Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury. Sci Rep. 2016;6:21709 pubmed publisher
  • western blot; human; loading ...; fig 7b
Lu S, Natarajan S, Mott J, Kharbanda K, Harrison Findik D. Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. PLoS ONE. 2016;11:e0147474 pubmed publisher
  • western blot; human
Kim H, Lim J, Kim J, Kim Y, Park S, Sohn J. Panaxydol, a component of Panax ginseng, induces apoptosis in cancer cells through EGFR activation and ER stress and inhibits tumor growth in mouse models. Int J Cancer. 2016;138:1432-41 pubmed publisher
  • western blot; human; loading ...; fig 1c
Palam L, Gore J, Craven K, Wilson J, Korc M. Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma. Cell Death Dis. 2015;6:e1913 pubmed publisher
  • western blot; mouse
Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher
  • western blot; human
Willy J, Young S, Stevens J, Masuoka H, Wek R. CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. Mol Biol Cell. 2015;26:2190-204 pubmed publisher
  • western blot; human; fig 2
Sheng X, Arnoldussen Y, Storm M, Tesikova M, Nenseth H, Zhao S, et al. Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Mol Med. 2015;7:788-801 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 1e
Zhang R, Wang R, Chen Q, Chang H. Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells. Mol Med Rep. 2015;12:1727-32 pubmed publisher
  • western blot; human; loading ...; fig 1c
  • western blot; rat; loading ...; fig 7b
Pilar Valdecantos M, Prieto Hontoria P, Pardo V, Módol T, Santamaría B, Weber M, et al. Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. Free Radic Biol Med. 2015;84:263-278 pubmed publisher
  • western blot; human; 1:250
Xie W, Pariollaud M, Wixted W, Chitnis N, Fornwald J, Truong M, et al. Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation. PLoS ONE. 2015;10:e0119738 pubmed publisher
  • western blot; human
Wang S, Chen X, Hu J, Jiang J, Li Y, Chan Salis K, et al. ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells. Mol Cancer Ther. 2015;14:877-88 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Omi T, Tanimukai H, Kanayama D, Sakagami Y, Tagami S, Okochi M, et al. Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor. Cell Death Dis. 2014;5:e1332 pubmed publisher
  • western blot; human; 1:1000; fig 3
Abuali G, Chaisaklert W, Stelloo E, Pazarentzos E, Hwang M, Qize D, et al. The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis. Oncogene. 2015;34:1718-28 pubmed publisher
  • western blot; mouse
Gonzalez Rodriguez A, Mayoral R, Agra N, Valdecantos M, Pardo V, Miquilena Colina M, et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis. 2014;5:e1179 pubmed publisher
  • immunocytochemistry; rat; 1:100; fig 4
Maier P, Zemoura K, Acu a M, Y venes G, Zeilhofer H, Benke D. Ischemia-like oxygen and glucose deprivation mediates down-regulation of cell surface ?-aminobutyric acidB receptors via the endoplasmic reticulum (ER) stress-induced transcription factor CCAAT/enhancer-binding protein (C/EBP)-homologous protein (CH. J Biol Chem. 2014;289:12896-907 pubmed publisher
  • immunohistochemistry; rat; 1:50
  • western blot; rat; 1:500
Carloni S, Albertini M, Galluzzi L, Buonocore G, Proietti F, Balduini W. Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: role of protein synthesis and autophagic pathways. Exp Neurol. 2014;255:103-12 pubmed publisher
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 6
Colin Cassin C, Yao X, Cerella C, Chbicheb S, Kuntz S, Mazerbourg S, et al. PPAR?-inactive ?2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells. Mol Carcinog. 2015;54:393-404 pubmed publisher
  • western blot; mouse; fig 1
Dickhout J, Carlisle R, Jerome D, Mohammed Ali Z, Jiang H, Yang G, et al. Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism. J Biol Chem. 2012;287:7603-14 pubmed publisher
Fink E, Moparthy S, Bagati A, Bianchi Smiraglia A, Lipchick B, Wolff D, et al. XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response. Cell Rep. 2018;25:212-223.e4 pubmed publisher
Han H, Chou C, Li R, Liu J, Zhang L, Zhu W, et al. Chalcomoracin is a potent anticancer agent acting through triggering Oxidative stress via a mitophagy- and paraptosis-dependent mechanism. Sci Rep. 2018;8:9566 pubmed publisher
Yanda M, Liu Q, Cebotaru L. A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector. J Biol Chem. 2018;293:11513-11526 pubmed publisher
Kim K, Kim S, Han D, Jo Y, Lee Y, Lee M. Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. Sci Rep. 2018;8:6789 pubmed publisher
Zakirova Z, Fanutza T, Bonet J, Readhead B, Zhang W, Yi Z, et al. Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions. PLoS Genet. 2018;14:e1007169 pubmed publisher
Jeong W, Bae H, Lim W, Bazer F, Lee H, Song G. The functional effects and mechanisms by which fibroblast growth factor 2 (FGF2) controls bovine mammary epithelial cells: Implications for the development and functionality of the bovine mammary gland. J Anim Sci. 2017;95:5365-5377 pubmed publisher
Jeong W, Bae H, Lim W, Bazer F, Song G. Adiponectin: A prosurvival and proproliferation signal that increases bovine mammary epithelial cell numbers and protects them from endoplasmic reticulum stress responses. J Anim Sci. 2017;95:5278-5289 pubmed publisher
Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed publisher
Sieber J, Wieder N, Ostrosky Frid M, Dvela Levitt M, Aygün O, Udeshi N, et al. Lysine trimethylation regulates 78-kDa glucose-regulated protein proteostasis during endoplasmic reticulum stress. J Biol Chem. 2017;292:18878-18885 pubmed publisher
Gates L, Shi J, Rohira A, Feng Q, Zhu B, Bedford M, et al. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017;292:14456-14472 pubmed publisher
Willy J, Young S, Mosley A, Gawrieh S, Stevens J, Masuoka H, et al. Function of inhibitor of Bruton's tyrosine kinase isoform ? (IBTK?) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response. J Biol Chem. 2017;292:14050-14065 pubmed publisher
Shen J, Ha D, Zhu G, Rangel D, Kobielak A, Gill P, et al. GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice. Proc Natl Acad Sci U S A. 2017;114:E4020-E4029 pubmed publisher
Qi Y, Ruan J, Wang M, Dai Y, Zhou Q, Gui S, et al. Effects of hyperbaric oxygen treatment on gastric cancer cell line SGC7901. Biomed Rep. 2017;6:475-479 pubmed publisher
Márton M, Kurucz A, Lizák B, Margittai E, Banhegyi G, Kapuy O. A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress-The Role of PERK Pathway. Int J Mol Sci. 2017;18: pubmed publisher
Rana T, Shinde V, Starr C, Kruglov A, Boitet E, Kotla P, et al. An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina. Cell Death Dis. 2014;5:e1578 pubmed publisher
Blumenthal G, Gills J, Ballas M, Bernstein W, Komiya T, Dechowdhury R, et al. A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors. Oncotarget. 2014;5:8161-72 pubmed
Lai D, Liu S, Karlsson A, Lee W, Wang K, Chen Y, et al. The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination. Oncotarget. 2014;5:7788-804 pubmed
Yang L, Wu L, Wang D, Li Y, Dou H, Tso M, et al. Role of endoplasmic reticulum stress in the loss of retinal ganglion cells in diabetic retinopathy. Neural Regen Res. 2013;8:3148-58 pubmed publisher
Baird T, Palam L, Fusakio M, Willy J, Davis C, McClintick J, et al. Selective mRNA translation during eIF2 phosphorylation induces expression of IBTK?. Mol Biol Cell. 2014;25:1686-97 pubmed publisher
Dezwaan McCabe D, Riordan J, Arensdorf A, Icardi M, Dupuy A, Rutkowski D. The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis. PLoS Genet. 2013;9:e1003937 pubmed publisher
Akazawa Y, Isomoto H, Matsushima K, Kanda T, Minami H, Yamaghchi N, et al. Endoplasmic reticulum stress contributes to Helicobacter pylori VacA-induced apoptosis. PLoS ONE. 2013;8:e82322 pubmed publisher
Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, et al. ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS ONE. 2013;8:e81170 pubmed publisher
Yang P, Lin Y, Shun C, Lin S, Wei T, Chuang S, et al. Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stress. Sci Rep. 2013;3:3219 pubmed publisher
Qu W, Xiao J, Zhang H, Chen Q, Wang Z, Shi H, et al. B19, a novel monocarbonyl analogue of curcumin, induces human ovarian cancer cell apoptosis via activation of endoplasmic reticulum stress and the autophagy signaling pathway. Int J Biol Sci. 2013;9:766-77 pubmed publisher
Weng C, Chiou S, Wang L, Kou M, Wang Y, Wu M. Arsenic trioxide induces unfolded protein response in vascular endothelial cells. Arch Toxicol. 2014;88:213-26 pubmed publisher
Teske B, Fusakio M, Zhou D, Shan J, McClintick J, Kilberg M, et al. CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis. Mol Biol Cell. 2013;24:2477-90 pubmed publisher
Ehren J, Maher P. Concurrent regulation of the transcription factors Nrf2 and ATF4 mediates the enhancement of glutathione levels by the flavonoid fisetin. Biochem Pharmacol. 2013;85:1816-26 pubmed publisher
Babcock J, Nguyen H, He Y, Hendricks J, Wek R, Quilliam L. Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response. J Biol Chem. 2013;288:15687-98 pubmed publisher
Fang L, Zhou Y, Cao H, Wen P, Jiang L, He W, et al. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS ONE. 2013;8:e60546 pubmed publisher
Nunez C, Rodrigues V, Gomes F, Moura R, Victorio S, Bombassaro B, et al. Defective regulation of adipose tissue autophagy in obesity. Int J Obes (Lond). 2013;37:1473-80 pubmed publisher
Chhunchha B, Fatma N, Kubo E, Rai P, Singh S, Singh D. Curcumin abates hypoxia-induced oxidative stress based-ER stress-mediated cell death in mouse hippocampal cells (HT22) by controlling Prdx6 and NF-?B regulation. Am J Physiol Cell Physiol. 2013;304:C636-55 pubmed publisher
Numata Y, Morimura T, Nakamura S, Hirano E, Kure S, Goto Y, et al. Depletion of molecular chaperones from the endoplasmic reticulum and fragmentation of the Golgi apparatus associated with pathogenesis in Pelizaeus-Merzbacher disease. J Biol Chem. 2013;288:7451-66 pubmed publisher
Chikka M, McCabe D, Tyra H, Rutkowski D. C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver. J Biol Chem. 2013;288:4405-15 pubmed publisher
White M, Johnson G, Zhang W, Hobrath J, Piazza G, Grimaldi M. Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: relevant similarities to and important differences from celecoxib. J Neurosci Res. 2013;91:393-406 pubmed publisher
Rojek A, Füchtbauer E, Füchtbauer A, Jelen S, Malmendal A, Fenton R, et al. Liver-specific Aquaporin 11 knockout mice show rapid vacuolization of the rough endoplasmic reticulum in periportal hepatocytes after amino acid feeding. Am J Physiol Gastrointest Liver Physiol. 2013;304:G501-15 pubmed publisher
Bartolomé A, Guillen C, Benito M. Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death. Autophagy. 2012;8:1757-68 pubmed publisher
Maclean K, Greiner L, Evans J, Sood S, Lhotak S, Markham N, et al. Cystathionine protects against endoplasmic reticulum stress-induced lipid accumulation, tissue injury, and apoptotic cell death. J Biol Chem. 2012;287:31994-2005 pubmed publisher
Katika M, Hendriksen P, de Ruijter N, Van Loveren H, Peijnenburg A. Immunocytological and biochemical analysis of the mode of action of bis (tri-n-butyltin) tri-oxide (TBTO) in Jurkat cells. Toxicol Lett. 2012;212:126-36 pubmed publisher
Lhotak S, Sood S, Brimble E, Carlisle R, Colgan S, Mazzetti A, et al. ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death. Am J Physiol Renal Physiol. 2012;303:F266-78 pubmed publisher
Dey S, Savant S, Teske B, Hatzoglou M, Calkhoven C, Wek R. Transcriptional repression of ATF4 gene by CCAAT/enhancer-binding protein ? (C/EBP?) differentially regulates integrated stress response. J Biol Chem. 2012;287:21936-49 pubmed publisher
Sheng R, Liu X, Zhang L, Gao B, Han R, Wu Y, et al. Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning. Autophagy. 2012;8:310-25 pubmed publisher
Urban P, Bilecová Rabajdová M, Marekova M, Vesela J. Progression of apoptic signaling from mesenteric ischemia-reperfusion injury to lungs: correlation in the level of ER chaperones expression. Mol Cell Biochem. 2012;362:133-40 pubmed publisher
Beriault D, Sharma S, Shi Y, Khan M, Werstuck G. Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE-/- mice. Atherosclerosis. 2011;219:134-40 pubmed publisher
Fatma N, Singh P, Chhunchha B, Kubo E, Shinohara T, Bhargavan B, et al. Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis. Am J Physiol Cell Physiol. 2011;301:C954-67 pubmed publisher
Theriault J, Palmer H, Pittman D. Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells. Biochem Biophys Res Commun. 2011;409:500-5 pubmed publisher
Garbow J, Doherty J, Schugar R, Travers S, Weber M, Wentz A, et al. Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet. Am J Physiol Gastrointest Liver Physiol. 2011;300:G956-67 pubmed publisher
Palam L, Baird T, Wek R. Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation. J Biol Chem. 2011;286:10939-49 pubmed publisher
Green C, Olson L. Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic ?-cells by stearoyl-CoA desaturase and Elovl6. Am J Physiol Endocrinol Metab. 2011;300:E640-9 pubmed publisher
Thorp E. Methods and models for monitoring UPR-associated macrophage death during advanced atherosclerosis. Methods Enzymol. 2011;489:277-96 pubmed publisher
Penas C, Verdu E, Asensio Pinilla E, Guzmán Lenis M, Herrando Grabulosa M, Navarro X, et al. Valproate reduces CHOP levels and preserves oligodendrocytes and axons after spinal cord injury. Neuroscience. 2011;178:33-44 pubmed publisher
Karaky R, Gobbo E, Opolon P, Delbe J, Courty J, Griscelli F, et al. HARP?111-136 enhances radiation-induced apoptosis of U87MG glioblastoma by induction of the proapoptotic protein CHOP. Int J Oncol. 2011;38:179-88 pubmed
Krajewska M, Xu L, Xu W, Krajewski S, Kress C, Cui J, et al. Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Res. 2011;1370:227-37 pubmed publisher
Dey S, Baird T, Zhou D, Palam L, Spandau D, Wek R. Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response. J Biol Chem. 2010;285:33165-74 pubmed publisher
Zhou L, Liu M, Zhang J, Chen H, Dong L, Liu F. DsbA-L alleviates endoplasmic reticulum stress-induced adiponectin downregulation. Diabetes. 2010;59:2809-16 pubmed publisher
Fan R, Li X, Gu X, Chan J, Xu G. Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis. Diabetes Obes Metab. 2010;12:815-24 pubmed publisher
Yahiro K, Morinaga N, Moss J, Noda M. Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling. Microb Pathog. 2010;49:153-63 pubmed publisher
Gable K, Gupta S, Han G, Niranjanakumari S, Harmon J, Dunn T. A disease-causing mutation in the active site of serine palmitoyltransferase causes catalytic promiscuity. J Biol Chem. 2010;285:22846-52 pubmed publisher
Chiribau C, Gaccioli F, Huang C, Yuan C, Hatzoglou M. Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis. Mol Cell Biol. 2010;30:3722-31 pubmed publisher
Kyriakakis E, Philippova M, Joshi M, Pfaff D, Bochkov V, Afonyushkin T, et al. T-cadherin attenuates the PERK branch of the unfolded protein response and protects vascular endothelial cells from endoplasmic reticulum stress-induced apoptosis. Cell Signal. 2010;22:1308-16 pubmed publisher
Cazanave S, Elmi N, Akazawa Y, Bronk S, Mott J, Gores G. CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis. Am J Physiol Gastrointest Liver Physiol. 2010;299:G236-43 pubmed publisher
Ogata T, Oishi Y, Higuchi M, Muraoka I. Fasting-related autophagic response in slow- and fast-twitch skeletal muscle. Biochem Biophys Res Commun. 2010;394:136-40 pubmed publisher
Zhao C, Zhang Y, Jiang S, Jiang L, Dai L. Both endoplasmic reticulum and mitochondria are involved in disc cell apoptosis and intervertebral disc degeneration in rats. Age (Dordr). 2010;32:161-77 pubmed publisher
Lloyd D, Wheeler M, Gekakis N. A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice. Diabetes. 2010;59:460-70 pubmed publisher
Fradejas N, Pastor M, Burgos M, Beyaert R, Tranque P, Calvo S. Caspase-11 mediates ischemia-induced astrocyte death: involvement of endoplasmic reticulum stress and C/EBP homologous protein. J Neurosci Res. 2010;88:1094-105 pubmed publisher
Vinay D, Kim C, Choi B, Kwon B. Origins and functional basis of regulatory CD11c+CD8+ T cells. Eur J Immunol. 2009;39:1552-63 pubmed publisher
Ogata T, Machida S, Oishi Y, Higuchi M, Muraoka I. Differential cell death regulation between adult-unloaded and aged rat soleus muscle. Mech Ageing Dev. 2009;130:328-36 pubmed publisher
Di Nardo A, Kramvis I, Cho N, Sadowski A, Meikle L, Kwiatkowski D, et al. Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner. J Neurosci. 2009;29:5926-37 pubmed publisher
Kim I, Shu C, Xu W, Shiau C, Grant D, Vasile S, et al. Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. J Biol Chem. 2009;284:1593-603 pubmed publisher
Su N, Kilberg M. C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene. J Biol Chem. 2008;283:35106-17 pubmed publisher
Haataja L, Gurlo T, Huang C, Butler P. Many commercially available antibodies for detection of CHOP expression as a marker of endoplasmic reticulum stress fail specificity evaluation. Cell Biochem Biophys. 2008;51:105-7 pubmed publisher
Li Y, Bevilacqua E, Chiribau C, Majumder M, Wang C, Croniger C, et al. Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the . J Biol Chem. 2008;283:22443-56 pubmed publisher
Nakanishi M, Tomaru Y, Miura H, Hayashizaki Y, Suzuki M. Identification of transcriptional regulatory cascades in retinoic acid-induced growth arrest of HepG2 cells. Nucleic Acids Res. 2008;36:3443-54 pubmed publisher
Yamaguchi Y, Larkin D, Lara Lemus R, Ramos Castaneda J, Liu M, Arvan P. Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK. J Biol Chem. 2008;283:17020-9 pubmed publisher
Zhou D, Palam L, Jiang L, Narasimhan J, Staschke K, Wek R. Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions. J Biol Chem. 2008;283:7064-73 pubmed publisher
Forlino A, Tani C, Rossi A, Lupi A, Campari E, Gualeni B, et al. Differential expression of both extracellular and intracellular proteins is involved in the lethal or nonlethal phenotypic variation of BrtlIV, a murine model for osteogenesis imperfecta. Proteomics. 2007;7:1877-91 pubmed
Fujita Y, Ito M, Nozawa Y, Yoneda M, Oshida Y, Tanaka M. CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations. Mitochondrion. 2007;7:80-8 pubmed
Wheeler D, Floege J, Lameire N. NDT contributes to a collection of 100 seminal papers published by Oxford University Press. Nephrol Dial Transplant. 2006;21:2047-8 pubmed
Thuerauf D, Marcinko M, Gude N, Rubio M, Sussman M, Glembotski C. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circ Res. 2006;99:275-82 pubmed
Oikawa K, Ishida T, Imamura T, Yoshida K, Takanashi M, Hattori H, et al. Generation of the novel monoclonal antibody against TLS/EWS-CHOP chimeric oncoproteins that is applicable to one of the most sensitive assays for myxoid and round cell liposarcomas. Am J Surg Pathol. 2006;30:351-6 pubmed
Anand S, Chakrabarti E, Kawamura H, Taylor C, Maytin E. Ultraviolet light (UVB and UVA) induces the damage-responsive transcription factor CHOP/gadd153 in murine and human epidermis: evidence for a mechanism specific to intact skin. J Invest Dermatol. 2005;125:323-33 pubmed
Li F, Hayashi T, Jin G, Deguchi K, Nagotani S, Nagano I, et al. The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers. Brain Res. 2005;1048:59-68 pubmed
Kubota K, Lee D, Tsuchiya M, Young C, Everett E, Martinez Mier E, et al. Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation. J Biol Chem. 2005;280:23194-202 pubmed
Hayashi T, Saito A, Okuno S, Ferrand Drake M, Dodd R, Chan P. Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons. J Cereb Blood Flow Metab. 2005;25:41-53 pubmed
Reimertz C, Kogel D, Rami A, Chittenden T, Prehn J. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol. 2003;162:587-97 pubmed
product information
Product Name :
GADD 153 (B-3) Antibody
Gene Name :
DDIT3
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7351
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
GADD 153
reactive species  :
m, r, h
Application :
WB, IP, IF, ELISA
Epitope :
FL (m)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA