product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Cdk7 (C-4) Antibody
catalog :
sc-7344
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-4
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 4b
Cayrol F, Praditsuktavorn P, Fernando T, Kwiatkowski N, Marullo R, Calvo Vidal M, et al. THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors. Nat Commun. 2017;8:14290 pubmed publisher
  • western blot; human; loading ...; fig 3a
Lacombe B, Morel M, Margottin Goguet F, Ramirez B. Specific Inhibition of HIV Infection by the Action of Spironolactone in T Cells. J Virol. 2016;90:10972-10980 pubmed publisher
  • immunoprecipitation; human
  • western blot; human
Kelso T, Baumgart K, Eickhoff J, Albert T, Antrecht C, Lemcke S, et al. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells. Mol Cell Biol. 2014;34:3675-88 pubmed publisher
Sharifnia T, Wawer M, Chen T, Huang Q, Weir B, Sizemore A, et al. Small-molecule targeting of brachyury transcription factor addiction in chordoma. Nat Med. 2019;25:292-300 pubmed publisher
Sela D, Chen L, Martin Brown S, Washburn M, Florens L, Conaway J, et al. Endoplasmic reticulum stress-responsive transcription factor ATF6? directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes. J Biol Chem. 2012;287:23035-45 pubmed publisher
Ganuza M, Saiz Ladera C, Canamero M, Gomez G, Schneider R, Blasco M, et al. Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion. EMBO J. 2012;31:2498-510 pubmed publisher
Helenius K, Yang Y, Alasaari J, Makela T. Mat1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipocyte differentiation. Mol Cell Biol. 2009;29:315-23 pubmed publisher
Prince T, Sun L, Matts R. Cdk2: a genuine protein kinase client of Hsp90 and Cdc37. Biochemistry. 2005;44:15287-95 pubmed
product information
Product Name :
Cdk7 (C-4) Antibody
Gene Name :
CDK7
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7344
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Cdk7
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA