product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
CBP (C-1) Antibody
catalog :
sc-7300
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-1
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 34
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; mouse; loading ...; fig 7b
  • western blot; mouse; 1:2000; loading ...; fig 7b
Walia M, Taylor S, Ho P, Martin T, Walkley C. Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53. Cell Death Dis. 2018;9:844 pubmed publisher
  • western blot; mouse; loading ...; fig s4c
Hervás Corpión I, Guiretti D, Alcaraz Iborra M, Olivares R, Campos Caro A, Barco A, et al. Early alteration of epigenetic-related transcription in Huntington's disease mouse models. Sci Rep. 2018;8:9925 pubmed publisher
  • chromatin immunoprecipitation; human; fig 2h
Wu Y, Zhang Z, Cenciarini M, Proietti C, Amasino M, Hong T, et al. Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis. Cancer Res. 2018;78:671-684 pubmed publisher
  • immunoprecipitation; human; fig s1
  • western blot; human; 1:200; fig s1
Crider A, Thakkar R, Ahmed A, Pillai A. Dysregulation of estrogen receptor beta (ERβ), aromatase (CYP19A1), and ER co-activators in the middle frontal gyrus of autism spectrum disorder subjects. Mol Autism. 2014;5:46 pubmed publisher
  • western blot; human
Ogiwara H, Kohno T. CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS ONE. 2012;7:e52810 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:300
Zhu X, Huang C, Li Q, Guo Q, Wang Y, He X, et al. Temporal distribution of p300/CBP immunoreactivity in the adult rat spinal dorsal horn following chronic constriction injury (CCI). Cell Mol Neurobiol. 2013;33:197-204 pubmed publisher
  • chromatin immunoprecipitation; rat
Bousiges O, Vasconcelos A, Neidl R, Cosquer B, Herbeaux K, Panteleeva I, et al. Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus. Neuropsychopharmacology. 2010;35:2521-37 pubmed publisher
Akande O, Damle P, Pop M, Sherman N, Szomju B, Litovchick L, et al. DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination. Cell Rep. 2019;26:3323-3335.e4 pubmed publisher
Kosmidis S, Polyzos A, Harvey L, Youssef M, Denny C, Dranovsky A, et al. RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. Cell Rep. 2018;25:959-973.e6 pubmed publisher
Zou Y, Uddin M, Padmanabhan S, Zhu Y, Bu P, Vancura A, et al. The proto-oncogene Bcl3 induces immune checkpoint PD-L1 expression, mediating proliferation of ovarian cancer cells. J Biol Chem. 2018;293:15483-15496 pubmed publisher
Vincek A, Patel J, Jaganathan A, Green A, Pierre Louis V, Arora V, et al. Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3. Molecules. 2018;23: pubmed publisher
Haery L, Lugo Picó J, Henry R, Andrews A, Gilmore T. Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth. Mol Cancer. 2014;13:29 pubmed publisher
Han M, Du Y, Song C, Yoo D. Degradation of CREB-binding protein and modulation of type I interferon induction by the zinc finger motif of the porcine reproductive and respiratory syndrome virus nsp1? subunit. Virus Res. 2013;172:54-65 pubmed publisher
Hyndman B, Thompson P, Bayly R, Côté G, LeBrun D. E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300. Biochim Biophys Acta. 2012;1819:446-53 pubmed publisher
Chiurchiù V, Maccarrone M, Orlacchio A. Compositions and methods for treatment of Parkinson's disease: a patent evaluation of WO2011/102847A1. Expert Opin Ther Pat. 2012;22:181-4 pubmed publisher
He H, Yu F, Sun C, Luo Y. CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes. PLoS ONE. 2011;6:e22088 pubmed publisher
Xue H, Qiao Y, Ni P, Wang J, Chen C, Huang G. A CRE that binds CREB and contributes to PKA-dependent regulation of the proximal promoter of human RAB25 gene. Int J Biochem Cell Biol. 2011;43:348-57 pubmed publisher
Shipp L, Lee J, Yu C, Pufall M, Zhang P, Scott D, et al. Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids. PLoS ONE. 2010;5:e13754 pubmed publisher
Manna P, Soh J, Stocco D. The involvement of specific PKC isoenzymes in phorbol ester-mediated regulation of steroidogenic acute regulatory protein expression and steroid synthesis in mouse Leydig cells. Endocrinology. 2011;152:313-25 pubmed publisher
Bates C, Pomerantz W, Mapp A. Transcriptional tools: Small molecules for modulating CBP KIX-dependent transcriptional activators. Biopolymers. 2011;95:17-23 pubmed publisher
Wang J, Liu X, Wu H, Ni P, Gu Z, Qiao Y, et al. CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Res. 2010;38:5366-83 pubmed publisher
Yang J, Jiang H, Chen S, Chen J, Xu S, Li W, et al. CBP knockdown inhibits angiotensin II-induced vascular smooth muscle cells proliferation through downregulating NF-kB transcriptional activity. Mol Cell Biochem. 2010;340:55-62 pubmed publisher
Sui L, Ren W, Li B. Administration of thyroid hormone increases reelin and brain-derived neurotrophic factor expression in rat hippocampus in vivo. Brain Res. 2010;1313:9-24 pubmed publisher
Garbati M, Alço G, Gilmore T. Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8. Cancer Lett. 2010;291:237-45 pubmed publisher
Zhang M, Poplawski M, Yen K, Cheng H, Bloss E, Zhu X, et al. Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling. PLoS Biol. 2009;7:e1000245 pubmed publisher
Manna P, Huhtaniemi I, Stocco D. Mechanisms of protein kinase C signaling in the modulation of 3',5'-cyclic adenosine monophosphate-mediated steroidogenesis in mouse gonadal cells. Endocrinology. 2009;150:3308-17 pubmed publisher
Manna P, Stocco D. Crosstalk of CREB and Fos/Jun on a single cis-element: transcriptional repression of the steroidogenic acute regulatory protein gene. J Mol Endocrinol. 2007;39:261-77 pubmed
Yin H, Glass J, Blanchard K. MOZ-TIF2 repression of nuclear receptor-mediated transcription requires multiple domains in MOZ and in the CID domain of TIF2. Mol Cancer. 2007;6:51 pubmed
Roy S, Tenniswood M. Site-specific acetylation of p53 directs selective transcription complex assembly. J Biol Chem. 2007;282:4765-71 pubmed
Cowger J, Torchia J. Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR). Biochemistry. 2006;45:13150-62 pubmed
Kajiyama Y, Tian J, Locker J. Characterization of distant enhancers and promoters in the albumin-alpha-fetoprotein locus during active and silenced expression. J Biol Chem. 2006;281:30122-31 pubmed
Velarde M, Iruthayanathan M, Eason R, Zhang D, Simmen F, Simmen R. Progesterone receptor transactivation of the secretory leukocyte protease inhibitor gene in Ishikawa endometrial epithelial cells involves recruitment of Krüppel-like factor 9/basic transcription element binding protein-1. Endocrinology. 2006;147:1969-78 pubmed
Megiorni F, Indovina P, Mora B, Mazzilli M. Minor expression of fascin-1 gene (FSCN1) in NTera2 cells depleted of CREB-binding protein. Neurosci Lett. 2005;381:169-74 pubmed
Ruas J, Poellinger L, Pereira T. Role of CBP in regulating HIF-1-mediated activation of transcription. J Cell Sci. 2005;118:301-11 pubmed
product information
Product Name :
CBP (C-1) Antibody
Gene Name :
CREBBP
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7300
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
CBP
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
C-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA