Xu X, Sun Y, Cen X, Shan B, Zhao Q, Xie T, et al. Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model. Protein Cell. 2021;: pubmed publisher

Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, et al. Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression. J Exp Clin Cancer Res. 2021;40:214 pubmed publisher

Silva Pinheiro P, Pardo Hernández C, Reyes A, Tilokani L, Mishra A, Cerutti R, et al. DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion. Nucleic Acids Res. 2021;49:5230-5248 pubmed publisher

Dahou H, Minati M, Jacquemin P, Assi M. Genetic Inactivation of Peroxiredoxin-I Impairs the Growth of Human Pancreatic Cancer Cells. Antioxidants (Basel). 2021;10: pubmed publisher

Rushworth L, Harle V, Repiščák P, Clark W, Shaw R, Hall H, et al. In vivo CRISPR/Cas9 knockout screen: TCEAL1 silencing enhances docetaxel efficacy in prostate cancer. Life Sci Alliance. 2020;3: pubmed publisher

Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed publisher

Somerville T, Biffi G, Da ler Plenker J, Hur S, He X, Vance K, et al. Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. elife. 2020;9: pubmed publisher

Onn L, Portillo M, Ilic S, Cleitman G, Stein D, Kaluski S, et al. SIRT6 is a DNA double-strand break sensor. elife. 2020;9: pubmed publisher

Nowialis P, Lopušná K, Opavska J, Haney S, Abraham A, Sheng P, et al. Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions. Nat Commun. 2019;10:4374 pubmed publisher

Rhee H, Shaib A, Rehbach K, Lee C, Seif P, Thomas C, et al. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 2019;27:2212-2228.e7 pubmed publisher

Kim J, He X, Liu J, Duan Z, Kim T, Gerard J, et al. Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression. J Biol Chem. 2019;294:8760-8772 pubmed publisher

Rademaker G, Hennequière V, Brohée L, Nokin M, Lovinfosse P, Durieux F, et al. Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene. 2018;37:4398-4412 pubmed publisher

Liu L, An D, Xu J, Shao B, Li X, Shi J. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front Mol Neurosci. 2018;11:76 pubmed publisher

Le Duff M, Gouju J, Jonchère B, Guillon J, Toutain B, Boissard A, et al. Regulation of senescence escape by the cdk4-EZH2-AP2M1 pathway in response to chemotherapy. Cell Death Dis. 2018;9:199 pubmed publisher

Wan Y, Wang L, Zhu C, Zheng Q, Wang G, Tong J, et al. Aptamer-Conjugated Extracellular Nanovesicles for Targeted Drug Delivery. Cancer Res. 2018;78:798-808 pubmed publisher

Pannérec A, Migliavacca E, de Castro A, Michaud J, Karaz S, Goulet L, et al. Vitamin B12 deficiency and impaired expression of amnionless during aging. J Cachexia Sarcopenia Muscle. 2018;9:41-52 pubmed publisher

Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed publisher

Groves J, Zachara N. Characterization of tools to detect and enrich human and mouse O-GlcNAcase. Glycobiology. 2017;: pubmed publisher

Sarper M, Allen M, Gomm J, Haywood L, Decock J, Thirkettle S, et al. Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res. 2017;19:33 pubmed publisher

Hardonnière K, Fernier M, Gallais I, Mograbi B, Podechard N, Le Ferrec E, et al. Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype. Sci Rep. 2017;7:195 pubmed publisher

Reynolds L, D Amico G, Lechertier T, Papachristodoulou A, Muñoz Félix J, De Arcangelis A, et al. Dual role of pericyte ?6?1-integrin in tumour blood vessels. J Cell Sci. 2017;130:1583-1595 pubmed publisher

Lee J, Hsu C, Michael M, Nanda A, Liu L, McMillan J, et al. Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23. Am J Hum Genet. 2017;100:364-370 pubmed publisher

Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher

Blomme A, Fahmy K, Peulen O, Costanza B, Fontaine M, Struman I, et al. Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes. Oncotarget. 2016;7:83669-83683 pubmed publisher

Swartz K, Wood S, Murthy T, Ramirez O, Qin G, Pillai M, et al. E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. Mol Cell Biol. 2017;37: pubmed publisher

Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed publisher

Frentzas S, Simoneau E, Bridgeman V, Vermeulen P, Foo S, Kostaras E, et al. Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. Nat Med. 2016;22:1294-1302 pubmed publisher

Jin Q, Ren Y, Wang M, Suraneni P, Li D, Crispino J, et al. Novel function of FAXDC2 in megakaryopoiesis. Blood Cancer J. 2016;6:e478 pubmed publisher

Schiera G, Di Liegro C, Puleo V, Colletta O, Fricano A, Cancemi P, et al. Extracellular vesicles shed by melanoma cells contain a modified form of H1.0 linker histone and H1.0 mRNA-binding proteins. Int J Oncol. 2016;49:1807-1814 pubmed publisher

Sayyed K, Vee M, Abdel Razzak Z, Jouan E, Stieger B, Denizot C, et al. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology. 2016;363-364:58-71 pubmed publisher

Yang W, Ng F, Chan K, Pu X, Poston R, Ren M, et al. Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction. PLoS Genet. 2016;12:e1006127 pubmed publisher

Roychowdhury S, McCullough R, Sanz Garcia C, Saikia P, Alkhouri N, Matloob A, et al. Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury. Hepatology. 2016;64:1518-1533 pubmed publisher

Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed publisher

Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed publisher

Rider M, Hurwitz S, Meckes D. ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles. Sci Rep. 2016;6:23978 pubmed publisher

Derangère V, Fumet J, Boidot R, Bengrine L, Limagne E, Chevriaux A, et al. Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?. Oncotarget. 2016;7:9309-21 pubmed publisher

Zhao B, Tan T, Mei Y, Yang J, Yu Y, Verma A, et al. H2AX deficiency is associated with erythroid dysplasia and compromised haematopoietic stem cell function. Sci Rep. 2016;6:19589 pubmed publisher

Cousin F, Jouan Lanhouet S, Théret N, Brenner C, Jouan E, Le Moigne Muller G, et al. The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer. Oncotarget. 2016;7:7161-78 pubmed publisher

Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher

Wen Q, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider R, et al. Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition. Nat Med. 2015;21:1473-80 pubmed publisher

Vétillard A, Jonchère B, Moreau M, Toutain B, Henry C, Fontanel S, et al. Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis. Oncotarget. 2015;6:43342-62 pubmed publisher

Maris P, Blomme A, Palacios A, Costanza B, Bellahcène A, Bianchi E, et al. Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer. PLoS Med. 2015;12:e1001871 pubmed publisher

Georgiannakis A, Burgoyne T, Lueck K, Futter C, Greenwood J, Moss S. Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9. J Immunol. 2015;195:3382-9 pubmed publisher

Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K. Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes. PLoS ONE. 2015;10:e0136952 pubmed publisher

Conigliaro A, Costa V, Lo Dico A, Saieva L, Buccheri S, Dieli F, et al. CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA. Mol Cancer. 2015;14:155 pubmed publisher

Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, et al. COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer. Mol Cancer. 2015;14:109 pubmed publisher

Alexandrova E, Yallowitz A, Li D, Xu S, Schulz R, Proia D, et al. Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment. Nature. 2015;523:352-6 pubmed publisher

Saini P, Li Y, Dobbelstein M. Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. Oncotarget. 2015;6:13072-87 pubmed

Decock J, Hendrickx W, Thirkettle S, Gutiérrez Fernández A, Robinson S, Edwards D. Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice. Breast Cancer Res. 2015;17:38 pubmed publisher

Grabner B, Schramek D, Mueller K, Moll H, Svinka J, Hoffmann T, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285 pubmed publisher

Kramer D, Schön M, Bayerlová M, Bleckmann A, Schön M, Zörnig M, et al. A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity. Cell Death Dis. 2015;6:e1634 pubmed publisher

Morlé A, Garrido C, Micheau O. Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion. Cell Death Dis. 2015;6:e1633 pubmed publisher

Bele A, Mirza S, Zhang Y, Ahmad Mir R, Lin S, Kim J, et al. The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells. Cell Cycle. 2015;14:990-1000 pubmed publisher

Pajaud J, Ribault C, Ben Mosbah I, Rauch C, Henderson C, Bellaud P, et al. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration. Cell Death Dis. 2015;6:e1598 pubmed publisher

Jonchère B, Vétillard A, Toutain B, Lam D, Bernard A, Henry C, et al. Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1. Oncotarget. 2015;6:409-26 pubmed

Barnes M, McMullen M, Roychowdhury S, Madhun N, Niese K, Olman M, et al. Macrophage migration inhibitory factor is required for recruitment of scar-associated macrophages during liver fibrosis. J Leukoc Biol. 2015;97:161-9 pubmed publisher

Nagarajan S, Hossan T, Alawi M, Najafova Z, Indenbirken D, Bedi U, et al. Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription. Cell Rep. 2014;8:460-9 pubmed publisher

Fukumoto Y, Morii M, Miura T, Kubota S, Ishibashi K, Honda T, et al. Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint. J Biol Chem. 2014;289:12313-29 pubmed publisher

Guegan J, Ezan F, Gailhouste L, Langouet S, Baffet G. MEK1/2 overactivation can promote growth arrest by mediating ERK1/2-dependent phosphorylation of p70S6K. J Cell Physiol. 2014;229:903-15 pubmed publisher

Bedi U, Scheel A, Hennion M, Begus Nahrmann Y, Ruschoff J, Johnsen S. SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms. Oncogene. 2015;34:465-73 pubmed publisher

Liu L, Wen Q, Gong R, Gilles L, Stankiewicz M, Guo M, et al. PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN. Cell Death Dis. 2014;5:e988 pubmed publisher

Xavier C, Melikova M, Chuman Y, Uren A, Baljinnyam B, Rubin J. Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/?-catenin signaling. Cell Signal. 2014;26:94-101 pubmed publisher

Batsukh T, Schulz Y, Wolf S, Rabe T, Oellerich T, Urlaub H, et al. Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex. PLoS ONE. 2012;7:e52640 pubmed publisher

Baljinnyam B, Klauzinska M, Saffo S, Callahan R, Rubin J. Recombinant R-spondin2 and Wnt3a up- and down-regulate novel target genes in C57MG mouse mammary epithelial cells. PLoS ONE. 2012;7:e29455 pubmed publisher

Chen Y, Schnetz M, Irarrazabal C, Shen R, Williams C, Burg M, et al. Proteomic identification of proteins associated with the osmoregulatory transcription factor TonEBP/OREBP: functional effects of Hsp90 and PARP-1. Am J Physiol Renal Physiol. 2007;292:F981-92 pubmed

Dinić M, Herholz M, Kačarević U, Radojević D, Novovic K, Đokić J, et al. Host-commensal interaction promotes health and lifespan in Caenorhabditis elegans through the activation of HLH-30/TFEB-mediated autophagy. Aging (Albany NY). 2021;13:8040-8054 pubmed publisher

Lees D, Reynolds L, Pedrosa A, Roy Luzarraga M, Hodivala Dilke K. Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression. Angiogenesis. 2021;24:471-482 pubmed publisher

Chen J, Yang Y, Russu W, Chan W. The Aryl Hydrocarbon Receptor Undergoes Chaperone-Mediated Autophagy in Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2021;22: pubmed publisher

Saini H, Sharma H, Mukherjee S, Chowdhury S, Chowdhury R. Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells. Cancer Cell Int. 2021;21:52 pubmed publisher

Huh D, Passarelli M, Gao J, Dusmatova S, Goin C, Fish L, et al. A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression. EMBO J. 2021;40:e106696 pubmed publisher

Abokyi S, Shan S, To C, Chan H, Tse D. Autophagy Upregulation by the TFEB Inducer Trehalose Protects against Oxidative Damage and Cell Death Associated with NRF2 Inhibition in Human RPE Cells. Oxid Med Cell Longev. 2020;2020:5296341 pubmed publisher

Anania S, Peiffer R, Rademaker G, Hego A, Thiry M, Deldicque L, et al. Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics' Machinery in Pancreas Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher

Kouloulia S, Hallin E, Simbriger K, Amorim I, Lach G, Amvrosiadis T, et al. Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Rep. 2019;29:3620-3635.e7 pubmed publisher

Ni Y, Schmidt K, Werner B, Koenig J, Guldner I, Schnepp P, et al. Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer. Nat Commun. 2019;10:2860 pubmed publisher

de Araujo E, Erdogan F, Neubauer H, Meneksedag Erol D, Manaswiyoungkul P, Eram M, et al. Structural and functional consequences of the STAT5BN642H driver mutation. Nat Commun. 2019;10:2517 pubmed publisher

Fang C, Kuo H, Hsu S, Yih L. HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes. Cell Div. 2019;14:4 pubmed publisher

Guillon J, Petit C, Moreau M, Toutain B, Henry C, Roche H, et al. Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment. Cell Death Dis. 2019;10:199 pubmed publisher

Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher

Kari V, Raul S, Henck J, Kitz J, Kramer F, Kosinsky R, et al. The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness. Clin Epigenetics. 2019;11:4 pubmed publisher

Ni Y, Zhou N, Xue W, Rong L, Yung W, Lin R, et al. A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating. Cell Discov. 2018;4:65 pubmed publisher

Somerville T, Xu Y, Miyabayashi K, Tiriac H, Cleary C, Maia Silva D, et al. TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Cell Rep. 2018;25:1741-1755.e7 pubmed publisher

Niu X, Su L, Qi S, Gao Z, Zhang Q, Zhang S. GRP75 modulates oncogenic Dbl-driven endocytosis derailed via the CHIP-mediated ubiquitin degradation pathway. Cell Death Dis. 2018;9:971 pubmed publisher

Lopez Charcas O, Espinosa A, Alfaro A, Herrera Carrillo Z, Ramírez Cordero B, Cortes Reynosa P, et al. The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity. Sci Rep. 2018;8:12995 pubmed publisher

Doğan S, Cerutti R, Benincá C, Brea Calvo G, Jacobs H, Zeviani M, et al. Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy. Cell Metab. 2018;28:764-775.e5 pubmed publisher

Roy S, Bag A, Dutta S, Polavaram N, Islam R, Schellenburg S, et al. Macrophage-Derived Neuropilin-2 Exhibits Novel Tumor-Promoting Functions. Cancer Res. 2018;78:5600-5617 pubmed publisher

Schulz Heddergott R, Stark N, Edmunds S, Li J, Conradi L, Bohnenberger H, et al. Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion. Cancer Cell. 2018;34:298-314.e7 pubmed publisher

Kremer A, Zonneveld M, Kremer A, van der Meijden E, Falkenburg J, Wauben M, et al. Natural T-cell ligands that are created by genetic variants can be transferred between cells by extracellular vesicles. Eur J Immunol. 2018;48:1621-1631 pubmed publisher

Archbold H, Jackson K, Arora A, Weskamp K, Tank E, Li X, et al. TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia. Sci Rep. 2018;8:4606 pubmed publisher

Oldach L, Gorshkov K, Mills W, Zhang J, Meffert M. A biosensor for MAPK-dependent Lin28 signaling. Mol Biol Cell. 2018;29:1157-1167 pubmed publisher

Baranes Bachar K, Levy Barda A, Oehler J, Reid D, Soria Bretones I, Voss T, et al. The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair. Mol Cell. 2018;69:866-878.e7 pubmed publisher

Paiva N, Pascoal L, Negreiros L, Portovedo M, Coope A, Ayrizono M, et al. Ileal pouch of ulcerative colitis and familial adenomatous polyposis patients exhibit modulation of autophagy markers. Sci Rep. 2018;8:2619 pubmed publisher

Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, et al. ERAD-dependent control of the Wnt secretory factor Evi. EMBO J. 2018;37: pubmed publisher

Iseka F, Goetz B, Mushtaq I, An W, Cypher L, Bielecki T, et al. Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function. J Immunol. 2018;200:483-499 pubmed publisher

Zhao B, Mei Y, Cao L, Zhang J, Sumagin R, Yang J, et al. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms. J Clin Invest. 2018;128:125-140 pubmed publisher

Zhao J, Tian Z, Kadomatsu T, Xie P, Miyata K, Sugizaki T, et al. Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice. J Biol Chem. 2018;293:1596-1609 pubmed publisher

Richter K, Revelo N, Seitz K, Helm M, Sarkar D, Saleeb R, et al. Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO J. 2018;37:139-159 pubmed publisher

Hong Y, Zhao T, Li X, Li S. Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes. J Neurosci. 2017;37:9550-9563 pubmed publisher

Kwun H, Wendzicki J, Shuda Y, Moore P, Chang Y. Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting. Oncogene. 2017;36:6784-6792 pubmed publisher

Srivastava S, Mohibi S, Mirza S, Band H, Band V. Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway. Cell Cycle. 2017;16:1515-1525 pubmed publisher

Edlinger L, Berger Becvar A, Menzl I, Hoermann G, Greiner G, Grundschober E, et al. Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1. Br J Haematol. 2017;179:229-241 pubmed publisher

Harden M, Munger K. Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles. Virology. 2017;508:63-69 pubmed publisher

Bowman C, Rodriguez S, Selen Alpergin E, Acoba M, Zhao L, Hartung T, et al. The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency. Cell Chem Biol. 2017;24:673-684.e4 pubmed publisher

Carter E, Gopsill J, Gomm J, Jones J, Grose R. A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer. Breast Cancer Res. 2017;19:50 pubmed publisher

Amen A, Ruiz Garzon C, Shi J, Subramanian M, Pham D, Meffert M. A Rapid Induction Mechanism for Lin28a in Trophic Responses. Mol Cell. 2017;65:490-503.e7 pubmed publisher

Chiavarina B, Nokin M, Bellier J, Durieux F, Blétard N, Sherer F, et al. Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer. Int J Mol Sci. 2017;18: pubmed publisher

Horiguchi H, Endo M, Kawane K, Kadomatsu T, Terada K, Morinaga J, et al. ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis. EMBO J. 2017;36:409-424 pubmed publisher

Roychoudhury S, Nath S, Song H, Hegde M, Bellot L, Mantha A, et al. Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity. Mol Cell Biol. 2017;37: pubmed publisher

Tian Z, Miyata K, Kadomatsu T, Horiguchi H, Fukushima H, Tohyama S, et al. ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism. Nat Commun. 2016;7:13016 pubmed publisher

Hardonnière K, Saunier E, Lemarié A, Fernier M, Gallais I, Héliès Toussaint C, et al. The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival. Sci Rep. 2016;6:30776 pubmed publisher

Zhang R, Witkowska K, Afonso Guerra Assunção J, Ren M, Ng F, Mauro C, et al. A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity. Hum Mol Genet. 2016;25:4117-4126 pubmed publisher

Mohibi S, Srivastava S, Bele A, Mirza S, Band H, Band V. Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Mol Cell Biol. 2016;36:2487-502 pubmed publisher

Nivarthi H, Gordziel C, Themanns M, Kramer N, Eberl M, Rabe B, et al. The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth. Oncotarget. 2016;7:51096-51106 pubmed publisher

Bhakat K, Sengupta S, Adeniyi V, Roychoudhury S, Nath S, Bellot L, et al. Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation. Oncotarget. 2016;7:22590-604 pubmed publisher

Legendre C, Avril S, Guillet C, Garcion E. Low oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells. BMC Cancer. 2016;16:51 pubmed publisher

Stokum J, Mehta R, Ivanova S, Yu E, Gerzanich V, Simard J. Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling. Acta Neuropathol Commun. 2015;3:61 pubmed publisher

Yen Y, Gassen N, Zellner A, Rein T, Landgraf R, Wotjak C, et al. Glycogen synthase kinase-3β inhibition in the medial prefrontal cortex mediates paradoxical amphetamine action in a mouse model of ADHD. Front Behav Neurosci. 2015;9:67 pubmed publisher

Iorio V, Festa M, Rosati A, Hahne M, Tiberti C, Capunzo M, et al. BAG3 regulates formation of the SNARE complex and insulin secretion. Cell Death Dis. 2015;6:e1684 pubmed publisher

Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung C, et al. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014;454-455:118-27 pubmed publisher

Mauer J, Chaurasia B, Goldau J, Vogt M, Ruud J, Nguyen K, et al. Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nat Immunol. 2014;15:423-30 pubmed publisher

Kales S, Nau M, Merchant A, Lipkowitz S. Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A. PLoS ONE. 2014;9:e87116 pubmed publisher

Robbez Masson L, Bodor C, Jones J, Hurst H, Fitzgibbon J, Hart I, et al. Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing. PLoS ONE. 2013;8:e78839 pubmed publisher

Al Dossary A, Strehler E, Martin DeLeon P. Expression and secretion of plasma membrane Ca2+-ATPase 4a (PMCA4a) during murine estrus: association with oviductal exosomes and uptake in sperm. PLoS ONE. 2013;8:e80181 pubmed publisher

Mukhopadhyay C, Zhao X, Maroni D, Band V, Naramura M. Distinct effects of EGFR ligands on human mammary epithelial cell differentiation. PLoS ONE. 2013;8:e75907 pubmed publisher

Putz E, Gotthardt D, Hoermann G, Csiszar A, Wirth S, Berger A, et al. CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance. Cell Rep. 2013;4:437-44 pubmed publisher

Smith M, Scaglione K, Assimon V, Patury S, Thompson A, Dickey C, et al. The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex. Biochemistry. 2013;52:5354-64 pubmed publisher

Hillian A, McMullen M, Sebastian B, Roychowdhury S, Rowchowdhury S, Kashyap S, et al. Mice lacking C1q are protected from high fat diet-induced hepatic insulin resistance and impaired glucose homeostasis. J Biol Chem. 2013;288:22565-75 pubmed publisher

Cheng Y, Wan X, McElfresh T, Chen X, Gresham K, Rosenbaum D, et al. Impaired contractile function due to decreased cardiac myosin binding protein C content in the sarcomere. Am J Physiol Heart Circ Physiol. 2013;305:H52-65 pubmed publisher

Matak P, Zumerle S, Mastrogiannaki M, El Balkhi S, Delga S, Mathieu J, et al. Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2? and altered expression of iron absorption genes in mice. PLoS ONE. 2013;8:e59538 pubmed publisher

Mukhopadhyay P, Lakshmanan I, Ponnusamy M, Chakraborty S, Jain M, Pai P, et al. MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells. PLoS ONE. 2013;8:e54455 pubmed publisher

Greer Y, Fields A, Brown A, Rubin J. Atypical protein kinase C? is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2. J Biol Chem. 2013;288:9438-46 pubmed publisher

Malinge S, Thiollier C, Chlon T, Dore L, Diebold L, Bluteau O, et al. Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling. Blood. 2013;121:2440-51 pubmed publisher

So J, Smolarek A, Salerno D, Maehr H, Uskokovic M, Liu F, et al. Targeting CD44-STAT3 signaling by Gemini vitamin D analog leads to inhibition of invasion in basal-like breast cancer. PLoS ONE. 2013;8:e54020 pubmed publisher

Ellis J, Wolfgang M. A genetically encoded metabolite sensor for malonyl-CoA. Chem Biol. 2012;19:1333-9 pubmed publisher

Guegan J, Ezan F, Theret N, Langouet S, Baffet G. MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells. Carcinogenesis. 2013;34:38-47 pubmed publisher

Legendre C, Reen F, Mooij M, McGlacken G, Adams C, O Gara F. Pseudomonas aeruginosa Alkyl quinolones repress hypoxia-inducible factor 1 (HIF-1) signaling through HIF-1? degradation. Infect Immun. 2012;80:3985-92 pubmed publisher

Zimmermann N, Zschocke J, Perisic T, Yu S, Holsboer F, Rein T. Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels. Biochem J. 2012;448:93-102 pubmed publisher

Li X, Kang Y, Zhang X, Zhu B, Fang W. Identification of a heat shock cognate protein 70 gene in Chinese soft-shell turtle (Pelodiscus sinensis) and its expression profiles under thermal stress. J Zhejiang Univ Sci B. 2012;13:465-77 pubmed publisher

Doyard M, Fatih N, Monnier A, Island M, Aubry M, Leroyer P, et al. Iron excess limits HHIPL-2 gene expression and decreases osteoblastic activity in human MG-63 cells. Osteoporos Int. 2012;23:2435-45 pubmed publisher

Xu F, Flowers S, Moran E. Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression. J Biol Chem. 2012;287:5033-41 pubmed publisher

Levy Barda A, Lerenthal Y, Davis A, Chung Y, Essers J, Shao Z, et al. Involvement of the nuclear proteasome activator PA28? in the cellular response to DNA double-strand breaks. Cell Cycle. 2011;10:4300-10 pubmed publisher

Windhorst S, Minge D, Bähring R, Hüser S, Schob C, Blechner C, et al. Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients. Cell Signal. 2012;24:750-7 pubmed publisher

Josse R, Dumont J, Fautrel A, Robin M, Guillouzo A. Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds. Toxicol Appl Pharmacol. 2012;258:176-87 pubmed publisher

Kari V, Shchebet A, Neumann H, Johnsen S. The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair. Cell Cycle. 2011;10:3495-504 pubmed publisher

Aravindan R, Fomin V, Naik U, Modelski M, Naik M, Galileo D, et al. CASK interacts with PMCA4b and JAM-A on the mouse sperm flagellum to regulate Ca2+ homeostasis and motility. J Cell Physiol. 2012;227:3138-50 pubmed publisher

Westmark P, Westmark C, Jeevananthan A, Malter J. Preparation of synaptoneurosomes from mouse cortex using a discontinuous percoll-sucrose density gradient. J Vis Exp. 2011;: pubmed publisher

Shi H, Hood K, Hayes M, Stubbs R. Proteomic analysis of advanced colorectal cancer by laser capture microdissection and two-dimensional difference gel electrophoresis. J Proteomics. 2011;75:339-51 pubmed publisher

Rageul J, Frémin C, Ezan F, Baffet G, Langouet S. The knock-down of ERCC1 but not of XPF causes multinucleation. DNA Repair (Amst). 2011;10:978-90 pubmed publisher

Chinn D, Holland W, Yoon J, Zwerdling T, Mack P. Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines. Pediatr Blood Cancer. 2012;58:885-90 pubmed publisher

Cheng Y, Li W, McElfresh T, Chen X, Berthiaume J, Castel L, et al. Changes in myofilament proteins, but not Ca²? regulation, are associated with a high-fat diet-induced improvement in contractile function in heart failure. Am J Physiol Heart Circ Physiol. 2011;301:H1438-46 pubmed publisher

Mueller K, Kornfeld J, Friedbichler K, Blaas L, Egger G, Esterbauer H, et al. Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. Hepatology. 2011;54:1398-409 pubmed publisher

Flowers S, Beck G, Moran E. Tissue-specific gene targeting by the multiprotein mammalian DREAM complex. J Biol Chem. 2011;286:27867-71 pubmed publisher

Rogue A, Lambert C, Josse R, Antherieu S, Spire C, Claude N, et al. Comparative gene expression profiles induced by PPAR? and PPAR?/? agonists in human hepatocytes. PLoS ONE. 2011;6:e18816 pubmed publisher

Zhang A, Zhou X, Wang X, Zhou H. Characterization of two heat shock proteins (Hsp70/Hsc70) from grass carp (Ctenopharyngodon idella): evidence for their differential gene expression, protein synthesis and secretion in LPS-challenged peripheral blood lymphocytes. Comp Biochem Physiol B Biochem Mol Biol. 2011;159:109-14 pubmed publisher

Kornfeld J, Meder S, Wohlberg M, Friedrich R, Rau T, Riethdorf L, et al. Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression. Br J Cancer. 2011;104:138-45 pubmed publisher

Dumont J, Josse R, Lambert C, Antherieu S, Laurent V, Loyer P, et al. Preferential induction of the AhR gene battery in HepaRG cells after a single or repeated exposure to heterocyclic aromatic amines. Toxicol Appl Pharmacol. 2010;249:91-100 pubmed publisher

Zachara N, Molina H, Wong K, Pandey A, Hart G. The dynamic stress-induced "O-GlcNAc-ome" highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways. Amino Acids. 2011;40:793-808 pubmed publisher

Hayden A, Johnson P, Packham G, Crabb S. S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition. Breast Cancer Res Treat. 2011;127:109-19 pubmed publisher

Duval H, Mbatchi S, Grandadam S, Legendre C, Loyer P, Ribault C, et al. Reperfusion stress induced during intermittent selective clamping accelerates rat liver regeneration through JNK pathway. J Hepatol. 2010;52:560-9 pubmed publisher

Blaas L, Kornfeld J, Schramek D, Musteanu M, Zollner G, Gumhold J, et al. Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis. Hepatology. 2010;51:1319-26 pubmed publisher

Camberlein E, Abgueguen E, Fatih N, Canonne Hergaux F, Leroyer P, Turlin B, et al. Hepcidin induction limits mobilisation of splenic iron in a mouse model of secondary iron overload. Biochim Biophys Acta. 2010;1802:339-46 pubmed publisher

Garnier D, Loyer P, Ribault C, Guguen Guillouzo C, Corlu A. Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration. Hepatology. 2009;50:1946-56 pubmed publisher

Patterson S, Li J, Kang J, Wickrema A, Williams D, Reithmeier R. Loss of specific chaperones involved in membrane glycoprotein biosynthesis during the maturation of human erythroid progenitor cells. J Biol Chem. 2009;284:14547-57 pubmed publisher

Flowers S, Nagl N, Beck G, Moran E. Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation. J Biol Chem. 2009;284:10067-75 pubmed publisher

Sinsimer K, Gratacós F, Knapinska A, Lu J, Krause C, Wierzbowski A, et al. Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay. Mol Cell Biol. 2008;28:5223-37 pubmed publisher

Bessard A, Frémin C, Ezan F, Fautrel A, Gailhouste L, Baffet G. RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo. Oncogene. 2008;27:5315-25 pubmed publisher

Jensen M, Schoepfer J, Radimerski T, Massey A, Guy C, Brueggen J, et al. NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. Breast Cancer Res. 2008;10:R33 pubmed publisher

Balasubramanian S, Ramos J, Luo W, Sirisawad M, Verner E, Buggy J. A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas. Leukemia. 2008;22:1026-34 pubmed publisher

McCrann D, Yezefski T, Nguyen H, Papadantonakis N, Liu H, Wen Q, et al. Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice. Blood. 2008;111:4092-5 pubmed publisher

Endo Y, Beauchamp E, Woods D, Taylor W, Toretsky J, Uren A, et al. Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism. Mol Cell Biol. 2008;28:2368-79 pubmed publisher

Jorgensen N, Andresen J, Pitt J, Swenson M, Zoghbi H, Orr H. Hsp70/Hsc70 regulates the effect phosphorylation has on stabilizing ataxin-1. J Neurochem. 2007;102:2040-2048 pubmed publisher

Yamaguchi T, Arai H, Katayama N, Ishikawa T, Kikumoto K, Atomi Y. Age-related increase of insoluble, phosphorylated small heat shock proteins in human skeletal muscle. J Gerontol A Biol Sci Med Sci. 2007;62:481-9 pubmed

Calabrese V, Mancuso C, Ravagna A, Perluigi M, Cini C, De Marco C, et al. In vivo induction of heat shock proteins in the substantia nigra following L-DOPA administration is associated with increased activity of mitochondrial complex I and nitrosative stress in rats: regulation by glutathione redox state. J Neurochem. 2007;101:709-17 pubmed

Gorria M, Huc L, Sergent O, Rebillard A, Gaboriau F, Dimanche Boitrel M, et al. Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport. Biochem Pharmacol. 2006;72:1343-53 pubmed

Mohan J, Gandhi A, Bhavya B, Rashmi R, Karunagaran D, Indu R, et al. Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol. J Biol Chem. 2006;281:17599-611 pubmed

Alexandrov P, Cui J, Zhao Y, Lukiw W. 24S-hydroxycholesterol induces inflammatory gene expression in primary human neural cells. Neuroreport. 2005;16:909-13 pubmed

Endo Y, Wolf V, Muraiso K, Kamijo K, Soon L, Uren A, et al. Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2. J Biol Chem. 2005;280:777-86 pubmed