product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PLC gamma1 (E-12) Antibody
catalog :
sc-7290
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E-12
reactivity :
human, mouse, rat, rabbit
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 28
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1b
Kostas M, Haugsten E, Zhen Y, Sørensen V, Szybowska P, Fiorito E, et al. Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors. Mol Cell Proteomics. 2018;17:850-870 pubmed publisher
  • western blot; mouse; loading ...; fig 12a
Wang H, Lee K, Pei Z, Khan A, Bakshi K, Burns L. PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis. Neurobiol Aging. 2017;55:99-114 pubmed publisher
  • western blot; mouse; loading ...; fig 5c
Zhou X, Packialakshmi B, Xiao Y, Nurmukhambetova S, Lees J. Progression of experimental autoimmune encephalomyelitis is associated with up-regulation of major sodium transporters in the mouse kidney cortex under a normal salt diet. Cell Immunol. 2017;317:18-25 pubmed publisher
  • western blot; mouse; loading ...; fig 4a
Ting W, Huang C, Jiang C, Lin Y, Chung L, Shen C, et al. Treatment with 17?-Estradiol Reduced Body Weight and the Risk of Cardiovascular Disease in a High-Fat Diet-Induced Animal Model of Obesity. Int J Mol Sci. 2017;18: pubmed publisher
  • western blot; human; 1:200; loading ...; fig s5
Zhong W, Yi Q, Xu B, Li S, Wang T, Liu F, et al. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. Nat Commun. 2016;7:12702 pubmed publisher
  • western blot; rat; loading ...; fig 1f
Stucky A, Bakshi K, Friedman E, Wang H. Prenatal Cocaine Exposure Upregulates BDNF-TrkB Signaling. PLoS ONE. 2016;11:e0160585 pubmed publisher
  • immunoprecipitation; rabbit; fig s2
  • western blot; rabbit; fig s2
Shi J, Miralles F, Birnbaumer L, Large W, Albert A. Store depletion induces Gαq-mediated PLCβ1 activity to stimulate TRPC1 channels in vascular smooth muscle cells. FASEB J. 2016;30:702-15 pubmed publisher
  • western blot; human; 1:500
Chun Y, Oh H, Park M, Kim T, Chung S. Increasing Membrane Cholesterol Level Increases the Amyloidogenic Peptide by Enhancing the Expression of Phospholipase C. J Neurodegener Dis. 2013;2013:407903 pubmed publisher
  • western blot; rabbit; loading ...; fig 1a
Skelton L, Boron W. Effect of acute acid-base disturbances on the phosphorylation of phospholipase C-γ1 and Erk1/2 in the renal proximal tubule. Physiol Rep. 2015;3: pubmed publisher
  • immunoprecipitation; human; fig 4
Bilal M, Zhang E, Dinkel B, Hardy D, Yankee T, Houtman J. GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells. Cell Signal. 2015;27:841-50 pubmed publisher
Lattanzio R, Iezzi M, Sala G, Tinari N, Falasca M, Alberti S, et al. PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes. BMC Cancer. 2019;19:747 pubmed publisher
Xia Z, Gu M, Jia X, Wang X, Wu C, Guo J, et al. Integrated DNA methylation and gene expression analysis identifies SLAMF7 as a key regulator of atherosclerosis. Aging (Albany NY). 2018;10:1324-1337 pubmed publisher
Guittard G, Dios Esponera A, Palmer D, Akpan I, Barr V, Manna A, et al. The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells. Sci Rep. 2018;8:5336 pubmed publisher
Sung K, Ferrari L, Yang W, Chung C, Zhao X, Gu Y, et al. Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception. J Neurosci. 2018;38:3394-3413 pubmed publisher
Hinterseher I, Schworer C, Lillvis J, Stahl E, Erdman R, Gatalica Z, et al. Immunohistochemical analysis of the natural killer cell cytotoxicity pathway in human abdominal aortic aneurysms. Int J Mol Sci. 2015;16:11196-212 pubmed publisher
Chan W, Sideris A, Sutachan J, Montoya G J, Blanck T, Recio Pinto E. Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neural stem/progenitors by ERK1/2, Akt, and PLC?. Front Mol Neurosci. 2013;6:23 pubmed publisher
Chun Y, Oh H, Park M, Cho H, Chung S. Cholesterol regulates HERG K+ channel activation by increasing phospholipase C β1 expression. Channels (Austin). 2013;7:275-87 pubmed
Lattanzio R, Marchisio M, La Sorda R, Tinari N, Falasca M, Alberti S, et al. Overexpression of activated phospholipase C?1 is a risk factor for distant metastases in T1-T2, N0 breast cancer patients undergoing adjuvant chemotherapy. Int J Cancer. 2013;132:1022-31 pubmed publisher
Lahariya C, Mishra A, Nandan D, Gautam P, Gupta S. Additional cash incentive within a conditional cash transfer scheme: a 'controlled before and during' design evaluation study from India. Indian J Public Health. 2011;55:115-20 pubmed publisher
Wang H, Crupi D, Liu J, Stucky A, Cruciata G, Di Rocco A, et al. Repetitive transcranial magnetic stimulation enhances BDNF-TrkB signaling in both brain and lymphocyte. J Neurosci. 2011;31:11044-54 pubmed publisher
Wang H, Stucky A, Liu J, Shen C, Trocme Thibierge C, Morain P. Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain. J Neurosci. 2009;29:10961-73 pubmed publisher
Schmidt U, Abramova A, Boucheron N, Eckelhart E, Schebesta A, Bilic I, et al. The protein tyrosine kinase Tec regulates mast cell function. Eur J Immunol. 2009;39:3228-38 pubmed publisher
Cha J, Maddileti S, Mitin N, Harden T, Der C. Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform. J Biol Chem. 2009;284:6227-40 pubmed publisher
Borgmann Winter K, Rawson N, Wang H, Wang H, MacDonald M, Ozdener M, et al. Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics. Neuroscience. 2009;158:642-53 pubmed publisher
Cai S, Brandt C. Induction of interleukin-6 in human retinal epithelial cells by an attenuated Herpes simplex virus vector requires viral replication and NFkappaB activation. Exp Eye Res. 2008;86:178-88 pubmed
Ignatiuk A, Quickfall J, Hawrysh A, Chamberlain M, Anderson D. The smaller isoforms of ankyrin 3 bind to the p85 subunit of phosphatidylinositol 3'-kinase and enhance platelet-derived growth factor receptor down-regulation. J Biol Chem. 2006;281:5956-64 pubmed
Wilson B, Pfeiffer J, Surviladze Z, Gaudet E, Oliver J. High resolution mapping of mast cell membranes reveals primary and secondary domains of Fc(epsilon)RI and LAT. J Cell Biol. 2001;154:645-58 pubmed
Nakamura I, Lipfert L, Rodan G, Le T Duong -. Convergence of alpha(v)beta(3) integrin- and macrophage colony stimulating factor-mediated signals on phospholipase Cgamma in prefusion osteoclasts. J Cell Biol. 2001;152:361-73 pubmed
product information
Product Name :
PLC gamma1 (E-12) Antibody
Gene Name :
PLCG1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7290
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
PLC gamma1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
C-terminal (bovine)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA