product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
caspase-3 (E-8) Antibody
catalog :
sc-7272
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E-8
reactivity :
gerbils, human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 119
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 5a
Chiang C, Hong Y. In situ delivery of biobutyrate by probiotic Escherichia coli for cancer therapy. Sci Rep. 2021;11:18172 pubmed publisher
  • western blot; human; loading ...; fig 4a
Lassiter R, Merchen T, Fang X, Wang Y. Protective Role of Kynurenine 3-Monooxygenase in Allograft Rejection and Tubular Injury in Kidney Transplantation. Front Immunol. 2021;12:671025 pubmed publisher
  • western blot; human; 1:1000; fig 5a
Chang N, Yeh C, Lin Y, Kuo K, Fong I, Kounis N, et al. Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways. Antioxidants (Basel). 2021;10: pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 3a
Molagoda I, Lee K, Choi Y, Kim G. Anthocyanins from Hibiscus syriacus L. Inhibit Oxidative Stress-Mediated Apoptosis by Activating the Nrf2/HO-1 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 4a
di Meco A, Pratico D. Early-life exposure to high-fat diet influences brain health in aging mice. Aging Cell. 2019;18:e13040 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 1s1a
Langer L, Ward J, Archer T. Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 11a
Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed publisher
  • western blot; human; loading ...; fig 3e
Hao M, Wang X, Jiao K. MicroRNA-17-5p mediates hypoxia-induced autophagy and inhibits apoptosis by targeting signal transducer and activator of transcription 3 in vascular smooth muscle cells. Exp Ther Med. 2017;13:935-941 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 4c
Wang H, Zuo Y, Ding M, Ke C, Yan R, Zhan H, et al. LASS2 inhibits growth and invasion of bladder cancer by regulating ATPase activity. Oncol Lett. 2017;13:661-668 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 4G
Wu Q, Yan H, Tao S, Wang X, Mou L, Chen P, et al. XIAP 3'-untranslated region as a ceRNA promotes FSCN1 function in inducing the progression of breast cancer by binding endogenous miR-29a-5p. Oncotarget. 2017;8:16784-16800 pubmed publisher
  • immunohistochemistry - frozen section; gerbils; 1:500; loading ...; fig 4
Choi I, Hwang L, Jin J, Ko I, Kim S, Shin M, et al. Dexmedetomidine alleviates cerebral ischemia-induced short-term memory impairment by inhibiting the expression of apoptosis-related molecules in the hippocampus of gerbils. Exp Ther Med. 2017;13:107-116 pubmed publisher
  • western blot; human; fig 4e
Riverso M, Montagnani V, Stecca B. KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth. Oncogene. 2017;36:3322-3333 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:75; loading ...; fig 6a
Cholewa B, Ndiaye M, Huang W, Liu X, Ahmad N. Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo. Cancer Lett. 2017;385:179-187 pubmed publisher
  • western blot; human; fig 5
Lee J, Jung H, Han Y, Yoon Y, Yun C, Sun H, et al. Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells. Mol Med Rep. 2016;14:3777-84 pubmed publisher
  • western blot; human; loading ...; fig 8a
Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7
Cheng W, Zhou R, Feng Y, Wang Y. Mainstream smoke and sidestream smoke affect the cardiac differentiation of mouse embryonic stem cells discriminately. Toxicology. 2016;357-358:1-10 pubmed publisher
  • western blot; human; 1:4000; loading ...; fig 3a
Zámbó V, Tóth M, Schlachter K, Szelényi P, Sarnyai F, Lotz G, et al. Cytosolic localization of NADH cytochrome b₅ oxidoreductase (Ncb5or). FEBS Lett. 2016;590:661-71 pubmed publisher
  • western blot; human; 1:1000; tbl 2
Wang G, Fu L, Chen F. Study of the mechanism underlying the inhibitory effects of transglutaminase II on apoptosis in the osteosarcoma MG-63 cell line under hypoxic conditions. Oncol Lett. 2015;10:3425-3428 pubmed
  • western blot; rat; 1:500; fig 4
Wang Z, Tang B, Tang F, Li Y, Zhang G, Zhong L, et al. Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D-Ala2, D-Leu5)-enkephalin through inhibition of the MKK7-JNK signaling pathway. Mol Med Rep. 2015;12:4079-4088 pubmed publisher
  • western blot; human; 1:500; fig  4
Zhang Q, Yu S, Huang X, Tan Y, Zhu C, Wang Y, et al. New insights into the function of Cullin 3 in trophoblast invasion and migration. Reproduction. 2015;150:139-49 pubmed publisher
  • western blot; rat
Shen X, Yang L, Yan S, Zheng H, Liang L, Cai X, et al. Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity. Mol Cell Endocrinol. 2015;412:1-11 pubmed publisher
  • western blot; human; fig f4
Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed
  • western blot; human; fig 3
Gomez Bougie P, Halliez M, Maïga S, Godon C, Kervoëlen C, Pellat Deceunynck C, et al. Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups. Cancer Biol Ther. 2015;16:60-5 pubmed publisher
  • western blot; human
George S, Vishwamitra D, Manshouri R, Shi P, Amin H. The ALK inhibitor ASP3026 eradicates NPM-ALK? T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget. 2014;5:5750-63 pubmed
  • western blot; human; 1:100
Chondrogiannis G, Kastamoulas M, Kanavaros P, Vartholomatos G, Bai M, Baltogiannis D, et al. Cytokine effects on cell viability and death of prostate carcinoma cells. Biomed Res Int. 2014;2014:536049 pubmed publisher
Badr El Din N, Shabana S, Abdulmajeed B, Ghoneum M. A novel kefir product (PFT) inhibits Ehrlich ascites carcinoma in mice via induction of apoptosis and immunomodulation. BMC Complement Med Ther. 2020;20:127 pubmed publisher
Jin B, An H. Baicalin alleviates benign prostate hyperplasia through androgen-dependent apoptosis. Aging (Albany NY). 2020;12:2142-2155 pubmed publisher
Cho H, Min H, Won Y, Ahn H, Cho Y, Seo K. Solid state fermentation process with Aspergillus kawachii enhances the cancer-suppressive potential of silkworm larva in hepatocellular carcinoma cells. BMC Complement Altern Med. 2019;19:241 pubmed publisher
Xie Y, Fan H, Lu W, Yang Q, Nurkesh A, Yeleussizov T, et al. Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer. Oncogene. 2019;38:2967-2983 pubmed publisher
Athavale D, Chouhan S, Pandey V, Mayengbam S, Singh S, Bhat M. Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9). Cancer Metab. 2018;6:16 pubmed publisher
Michel O, Kulbacka J, Saczko J, Mączyńska J, Błasiak P, Rossowska J, et al. Electroporation with Cisplatin against Metastatic Pancreatic Cancer: In Vitro Study on Human Primary Cell Culture. Biomed Res Int. 2018;2018:7364539 pubmed publisher
Luna A, Santos Filho J, Hesse H, Neto S, Chierice G, Maria D. Modulation of pro-apoptotic effects and mitochondrial potential on B16F10 cells by DODAC/PHO-S liposomes. BMC Res Notes. 2018;11:126 pubmed publisher
Ma J, Guo W, Chen X. Overexpressing microRNA-150 attenuates hypoxia-induced human cardiomyocyte cell apoptosis by targeting glucose-regulated protein-94. Mol Med Rep. 2018;17:4181-4186 pubmed publisher
Wang X, Liu W, Zhuang D, Hong S, Chen J. Sestrin2 and sestrin3 suppress NK-92 cell-mediated cytotoxic activity on ovarian cancer cells through AMPK and mTORC1 signaling. Oncotarget. 2017;8:90132-90143 pubmed publisher
Grey W, Ivey A, Milne T, Haferlach T, Grimwade D, Uhlmann F, et al. The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability. Biochim Biophys Acta Mol Cell Res. 2018;1865:105-116 pubmed publisher
Xu J, Jia X, Gu Y, Lewis D, Gu X, Wang Y. Vitamin D Reduces Oxidative Stress-Induced Procaspase-3/ROCK1 Activation and MP Release by Placental Trophoblasts. J Clin Endocrinol Metab. 2017;102:2100-2110 pubmed publisher
Song X, Ding Y, Liu G, Yang X, Zhao R, Zhang Y, et al. Cancer Cell-derived Exosomes Induce Mitogen-activated Protein Kinase-dependent Monocyte Survival by Transport of Functional Receptor Tyrosine Kinases. J Biol Chem. 2016;291:8453-64 pubmed publisher
Schaefer Klein J, Murphy S, Johnson S, Vasmatzis G, Kovtun I. Topoisomerase 2 Alpha Cooperates with Androgen Receptor to Contribute to Prostate Cancer Progression. PLoS ONE. 2015;10:e0142327 pubmed publisher
Holczer M, Márton M, Kurucz A, Bánhegyi G, Kapuy O. A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress. Biomed Res Int. 2015;2015:319589 pubmed publisher
Cho Y, Shin M, Ko I, Kim S, Kim C, Sung Y, et al. Ulinastatin inhibits cerebral ischemia-induced apoptosis in the hippocampus of gerbils. Mol Med Rep. 2015;12:1796-802 pubmed publisher
Kim S, Ko I, Shin M, Kim C, Ko Y, Cho H. Neuroprotective effects of bovine colostrum on intracerebral hemorrhage-induced apoptotic neuronal cell death in rats. Neural Regen Res. 2012;7:1715-21 pubmed publisher
Kapuy O, Vinod P, Bánhegyi G. mTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress - An experimental and modeling study. FEBS Open Bio. 2014;4:704-13 pubmed publisher
Maitra R, Seetharam R, Tesfa L, Augustine T, Klampfer L, Coffey M, et al. Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan. Oncotarget. 2014;5:2807-19 pubmed
Li W, Liu D, Chang W, Lu X, Wang Y, Zhu C, et al. Role of IGF2BP3 in trophoblast cell invasion and migration. Cell Death Dis. 2014;5:e1025 pubmed publisher
Sato K, Yama K, Murao Y, Tatsunami R, Tampo Y. Epalrestat increases intracellular glutathione levels in Schwann cells through transcription regulation. Redox Biol. 2013;2:15-21 pubmed publisher
Deng S, Wang M, Yan Z, Tian Z, Chen H, Yang X, et al. Autophagy in retinal ganglion cells in a rhesus monkey chronic hypertensive glaucoma model. PLoS ONE. 2013;8:e77100 pubmed publisher
Wang Y, Li C, Pan L, Gao Z. 7,8-Dihydroxycoumarin inhibits A549 human lung adenocarcinoma cell proliferation by inducing apoptosis via suppression of Akt/NF-?B signaling. Exp Ther Med. 2013;5:1770-1774 pubmed
Yan K, Lee L, Hsieh M, Yan M, Yao C, Chang P, et al. Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells. Oncol Rep. 2013;30:1497-505 pubmed publisher
Arnold K, Goeckeler Z, Wysolmerski R. Loss of focal adhesion kinase enhances endothelial barrier function and increases focal adhesions. Microcirculation. 2013;20:637-49 pubmed publisher
Lee J, Kim H, Yoon N, Lee W, Min Y, Ko B, et al. Tumor suppressor p53 plays a key role in induction of both tristetraprolin and let-7 in human cancer cells. Nucleic Acids Res. 2013;41:5614-25 pubmed publisher
Liang P, Li H, Zhou Z, Jin Y, Wang S, Peng X, et al. Overexpression of immunoglobulin G prompts cell proliferation and inhibits cell apoptosis in human urothelial carcinoma. Tumour Biol. 2013;34:1783-91 pubmed publisher
Gai L, Cai N, Wang L, Xu X, Kong X. Ursolic acid induces apoptosis via Akt/NF-?B signaling suppression in T24 human bladder cancer cells. Mol Med Rep. 2013;7:1673-7 pubmed publisher
Zhang M, Sun Y, Luo S. Ani-survivin DNAzymes inhibit cell proliferation and migration in breast cancer cell line MCF-7. Asian Pac J Cancer Prev. 2012;13:6233-7 pubmed
Zhang Q, Chen Q, Lu X, Zhou Z, Zhang H, Lin H, et al. CUL1 promotes trophoblast cell invasion at the maternal-fetal interface. Cell Death Dis. 2013;4:e502 pubmed publisher
Barbetti V, Gozzini A, Cheloni G, Marzi I, Fabiani E, Santini V, et al. Time- and residue-specific differences in histone acetylation induced by VPA and SAHA in AML1/ETO-positive leukemia cells. Epigenetics. 2013;8:210-9 pubmed publisher
Margheri F, Schiavone N, Papucci L, Magnelli L, Serrati S, Chillà A, et al. GDF5 regulates TGFß-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFß peptides. PLoS ONE. 2012;7:e50342 pubmed publisher
Semeláková M, Mikes J, Jendželovský R, Fedorocko P. The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells. J Photochem Photobiol B. 2012;117:115-25 pubmed publisher
Venkatesan N, Krishnakumar S, Deepa P, Deepa M, Khetan V, Reddy M. Molecular deregulation induced by silencing of the high mobility group protein A2 gene in retinoblastoma cells. Mol Vis. 2012;18:2420-37 pubmed
Tas U, Ekici F, Koc F, Sogut E, Ayan M, Kuloglu T, et al. Acute cardiotoxic effects of high dose toluene: an experimental study. Anadolu Kardiyol Derg. 2013;13:3-8 pubmed publisher
Bai M, Doukas M, Papoudou Bai A, Barbouti A, Stefanaki K, Galani V, et al. Immunohistological analysis of cell cycle and apoptosis regulators in thymus. Ann Anat. 2013;195:159-65 pubmed publisher
Pietschmann K, Bolck H, Buchwald M, Spielberg S, Polzer H, Spiekermann K, et al. Breakdown of the FLT3-ITD/STAT5 axis and synergistic apoptosis induction by the histone deacetylase inhibitor panobinostat and FLT3-specific inhibitors. Mol Cancer Ther. 2012;11:2373-83 pubmed publisher
Waheed A, Barker J, Barton S, Owen C, Ahmed S, Carew M. A novel steroidal saponin glycoside from Fagonia indica induces cell-selective apoptosis or necrosis in cancer cells. Eur J Pharm Sci. 2012;47:464-73 pubmed publisher
Sfikas A, Batsi C, Tselikou E, Vartholomatos G, Monokrousos N, Pappas P, et al. The canonical NF-?B pathway differentially protects normal and human tumor cells from ROS-induced DNA damage. Cell Signal. 2012;24:2007-23 pubmed publisher
Jendželovský R, Kovaľ J, Mikes J, Papčová Z, Plšíková J, Fedorocko P. Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells. Toxicol In Vitro. 2012;26:775-82 pubmed publisher
Ayan M, Tas U, Sogut E, Kuloglu T, Cayli S, Kocaman N, et al. The apoptotic effect of a high dose of toluene on liver tissue during the acute phase: an experimental study. Toxicol Ind Health. 2013;29:728-36 pubmed publisher
Tsapakidis K, Vlachostergios P, Voutsadakis I, Befani C, Patrikidou A, Hatzidaki E, et al. Bortezomib reverses the proliferative and antiapoptotic effect of neuropeptides on prostate cancer cells. Int J Urol. 2012;19:565-74 pubmed publisher
Kim S, Kima D, Jeong Y, Moon S, Kwon S, Park K. Indole-3-carbinol and ultraviolet B induce apoptosis of human melanoma cells via down-regulation of MITF. Pharmazie. 2011;66:982-7 pubmed
Ma Y, Zhang A, Shi Z, He C, Ding J, Wang X, et al. A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells. Toxicol In Vitro. 2012;26:414-20 pubmed publisher
Aldridge B, Gaudet S, Lauffenburger D, Sorger P. Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis. Mol Syst Biol. 2011;7:553 pubmed publisher
Pietschmann K, Buchwald M, Müller S, Knauer S, Kögl M, Heinzel T, et al. Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1. Int J Biochem Cell Biol. 2012;44:132-8 pubmed publisher
Bakshi K, Kosciuk M, Nagele R, Friedman E, Wang H. Prenatal cocaine exposure increases synaptic localization of a neuronal RasGEF, GRASP-1 via hyperphosphorylation of AMPAR anchoring protein, GRIP. PLoS ONE. 2011;6:e25019 pubmed publisher
Jiang Y, Huang Y, Cheng C, Lu W, Zhang Y, Liu X, et al. Combination of thiazolidinedione and hydralazine suppresses proliferation and induces apoptosis by PPAR? up-expression in MDA-MB-231 cells. Exp Mol Pathol. 2011;91:768-74 pubmed publisher
Formisano L, Guida N, Cocco S, Secondo A, Sirabella R, Ulianich L, et al. The repressor element 1-silencing transcription factor is a novel molecular target for the neurotoxic effect of the polychlorinated biphenyl mixture aroclor 1254 in neuroblastoma SH-SY5Y cells. J Pharmacol Exp Ther. 2011;338:997-1003 pubmed publisher
Oliver L, Hue E, Rossignol J, Bougras G, Hulin P, Naveilhan P, et al. Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation. PLoS ONE. 2011;6:e19820 pubmed publisher
Xia D, Shen K, Zhong W, Pan H. Administration of minocycline ameliorates damage in a renal ischemia/reperfusion injury model. Clin Invest Med. 2011;34:E55-63 pubmed
Jeong Y, Li H, Kim S, Park W, Yun H, Baek K, et al. Photo-activated 5-hydroxyindole-3-acetic acid induces apoptosis of prostate and bladder cancer cells. J Photochem Photobiol B. 2011;103:50-6 pubmed publisher
Jeong J, Jin C, Park C, Hong S, Kim G, Jeong Y, et al. Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells. Toxicol In Vitro. 2011;25:817-24 pubmed publisher
Li Z, Liu N, Zhang L, Gong K, Cai Y, Gao W, et al. Proteomic profiling reveals comprehensive insights into adrenergic receptor-mediated hypertrophy in neonatal rat cardiomyocytes. Proteomics Clin Appl. 2009;3:1407-21 pubmed publisher
Kim S, Ryu J, Li H, Park W, Yun H, Baek K, et al. UVB-activated indole-3-acetic acid induces apoptosis of PC-3 prostate cancer cells. Anticancer Res. 2010;30:4607-12 pubmed
Bier C, Knauer S, Klapthor A, Schweitzer A, Rekik A, Kramer O, et al. Cell-based analysis of structure-function activity of threonine aspartase 1. J Biol Chem. 2011;286:3007-17 pubmed publisher
Vondálová Blanárová O, Jelínková I, Szöor A, Skender B, Soucek K, Horváth V, et al. Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway. Carcinogenesis. 2011;32:42-51 pubmed publisher
Li D, Guo J, Huang J, Wang L, Deng R, Liu J, et al. Rhabdastrellic acid-A induced autophagy-associated cell death through blocking Akt pathway in human cancer cells. PLoS ONE. 2010;5:e12176 pubmed publisher
Choi H, Ko Y, Lee J, Kwon O, Kim S, Cheong C, et al. Neuroprotective effects of consuming bovine colostrum after focal brain ischemia/reperfusion injury in rat model. Nutr Res Pract. 2010;4:196-202 pubmed publisher
Baluchamy S, Ravichandran P, Periyakaruppan A, Ramesh V, Hall J, Zhang Y, et al. Induction of cell death through alteration of oxidants and antioxidants in lung epithelial cells exposed to high energy protons. J Biol Chem. 2010;285:24769-74 pubmed publisher
Buchwald M, Pietschmann K, Muller J, Bohmer F, Heinzel T, Krämer O. Ubiquitin conjugase UBCH8 targets active FMS-like tyrosine kinase 3 for proteasomal degradation. Leukemia. 2010;24:1412-21 pubmed publisher
Takahashi K, Tatsunami R, Oba T, Tampo Y. Buthionine sulfoximine promotes methylglyoxal-induced apoptotic cell death and oxidative stress in endothelial cells. Biol Pharm Bull. 2010;33:556-60 pubmed
Gieseg S, Amit Z, Yang Y, Shchepetkina A, Katouah H. Oxidant production, oxLDL uptake, and CD36 levels in human monocyte–derived macrophages are downregulated by the macrophage-generated antioxidant 7,8-dihydroneopterin. Antioxid Redox Signal. 2010;13:1525-34 pubmed publisher
Jeong Y, Oh M, Kim S, Li H, Yun H, Baek K, et al. Indole-3-acetic acid/horseradish peroxidase induces apoptosis in TCCSUP human urinary bladder carcinoma cells. Pharmazie. 2010;65:122-6 pubmed
Jendželovský R, Mikes J, Kovaľ J, Soucek K, Prochazkova J, Kello M, et al. Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells. Photochem Photobiol Sci. 2009;8:1716-23 pubmed publisher
Ou X, Stockmeier C, Meltzer H, Overholser J, Jurjus G, Dieter L, et al. A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. Biol Psychiatry. 2010;67:855-63 pubmed publisher
Yan K, Yao C, Chang H, Lai G, Cheng A, Chuang S. The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells. Mol Carcinog. 2010;49:235-46 pubmed publisher
Mikes J, Kovaľ J, Jendželovský R, Sacková V, Uhrinová I, Kello M, et al. The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells. Photochem Photobiol Sci. 2009;8:1558-67 pubmed publisher
Park K, Kim S, Kim D. Experimental photodynamic therapy for liver cancer cell-implanted nude mice by an indole-3-acetic acid and intense pulsed light combination. Biol Pharm Bull. 2009;32:1609-13 pubmed
Castro G, Maria D, Bouhallab S, Sgarbieri V. In vitro impact of a whey protein isolate (WPI) and collagen hydrolysates (CHs) on B16F10 melanoma cells proliferation. J Dermatol Sci. 2009;56:51-7 pubmed publisher
Jiang H, Shang X, Wu H, Huang G, Wang Y, Al Holou S, et al. Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells. Neurochem Res. 2010;35:152-61 pubmed publisher
Li C, Chen H, Ding F, Zhang Y, Luo A, Wang M, et al. A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway. Biochem J. 2009;422:363-72 pubmed publisher
Sun J, Li Z, Hu Z, Zeng Z, Yang D, Jiang W. Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells. Oncol Rep. 2009;22:193-8 pubmed
Rizzo A, Montorfano G, Negroni M, Corsetto P, Berselli P, Marciani P, et al. Simulated microgravity induce glutathione antioxidant pathway in Xenopus laevis embryos. Cell Biol Int. 2009;33:893-8 pubmed publisher
Bairey O, Vanichkin A, Shpilberg O. Arsenic-trioxide-induced apoptosis of chronic lymphocytic leukemia cells. Int J Lab Hematol. 2010;32:e77-85 pubmed publisher
Serrati S, Margheri F, Pucci M, Cantelmo A, Cammarota R, Dotor J, et al. TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis. Biochem Pharmacol. 2009;77:813-25 pubmed publisher
Kleban J, Mikes J, Horváth V, Sacková V, Hofmanova J, Kozubik A, et al. Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin. J Photochem Photobiol B. 2008;93:108-18 pubmed publisher
Lin X, He C, Xiao T, Jin X, Chen J, Wang Y, et al. Acitretin induces apoptosis through CD95 signalling pathway in human cutaneous squamous cell carcinoma cell line SCL-1. J Cell Mol Med. 2009;13:2888-98 pubmed publisher
Chung Y, Troy H, Kristeleit R, Aherne W, Jackson L, Atadja P, et al. Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts. Neoplasia. 2008;10:303-13 pubmed
Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F. Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer. BMC Cancer. 2008;8:74 pubmed publisher
Kramer O, Müller S, Buchwald M, Reichardt S, Heinzel T. Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. FASEB J. 2008;22:1369-79 pubmed
Sun J, Ying M, Li H, Shang X, He Y, Chen K, et al. Role of UCH-L1/ubiquitin in acute testicular ischemia-reperfusion injury. Biochem Biophys Res Commun. 2008;366:539-44 pubmed
Barbetti V, Gozzini A, Rovida E, Morandi A, Spinelli E, Fossati G, et al. Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells. Oncogene. 2008;27:1767-78 pubmed
Tian Z, Pan R, Chang Q, Si J, Xiao P, Wu E. Cimicifuga foetida extract inhibits proliferation of hepatocellular cells via induction of cell cycle arrest and apoptosis. J Ethnopharmacol. 2007;114:227-33 pubmed
Tian Z, Shen J, Moseman A, Yang Q, Yang J, Xiao P, et al. Dulxanthone A induces cell cycle arrest and apoptosis via up-regulation of p53 through mitochondrial pathway in HepG2 cells. Int J Cancer. 2008;122:31-8 pubmed
Lu Y, Zhang Z, Liu Q, Liu B, Song X, Wang M, et al. Immunological protection against HPV16 E7-expressing human esophageal cancer cell challenge by a novel HPV16-E6/E7 fusion protein based-vaccine in a Hu-PBL-SCID mouse model. Biol Pharm Bull. 2007;30:150-6 pubmed
Rovida E, Gozzini A, Barbetti V, Giuntoli S, Santini V, Dello Sbarba P. The c-Jun-N-terminal-Kinase inhibitor SP600125 enhances the butyrate derivative D1-induced apoptosis via caspase 8 activation in Kasumi 1 t(8;21) acute myeloid leukaemia cells. Br J Haematol. 2006;135:653-9 pubmed
Li B, Liu X, Fan J, Qi R, Bo L, Gu J, et al. A survivin-mediated oncolytic adenovirus induces non-apoptotic cell death in lung cancer cells and shows antitumoral potential in vivo. J Gene Med. 2006;8:1232-42 pubmed
Kim D, Jeon S, Jeong Y, Kim S, Kwon S, Park K. Hydrogen peroxide is a mediator of indole-3-acetic acid/horseradish peroxidase-induced apoptosis. FEBS Lett. 2006;580:1439-46 pubmed
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product information
Product Name :
caspase-3 (E-8) Antibody
Gene Name :
CASP3
Size :
200 µg/ml
Catalog Number :
sc-7272
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
caspase-3
reactive species  :
human
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA