product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
NOS2 (C-11) Antibody
catalog :
sc-7271
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-11
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 72
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2b
Bando H, Lee Y, Sakaguchi N, Pradipta A, Sakamoto R, Tanaka S, et al. Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons. Front Cell Infect Microbiol. 2019;9:140 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s21
  • immunocytochemistry; mouse; 1:100; loading ...; fig 5b
  • western blot; mouse; 1:400; loading ...; fig s18a
Kang H, Yang B, Zhang K, Pan Q, Yuan W, Li G, et al. Immunoregulation of macrophages by dynamic ligand presentation via ligand-cation coordination. Nat Commun. 2019;10:1696 pubmed publisher
  • western blot; mouse; fig 4j
  • western blot; human; loading ...; fig 4j
Bando H, Lee Y, Sakaguchi N, Pradipta A, Ma J, Tanaka S, et al. Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response. MBio. 2018;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 3a
Neumann L, Mueller M, Moos V, Heller F, Meyer T, Loddenkemper C, et al. Mucosal Inducible NO Synthase-Producing IgA+ Plasma Cells in Helicobacter pylori-Infected Patients. J Immunol. 2016;197:1801-8 pubmed publisher
  • western blot; mouse; loading ...; fig 3
Wang R, Feng X, Zhu K, Zhao X, Suo H. Preventive activity of banana peel polyphenols on CCl4-induced experimental hepatic injury in Kunming mice. Exp Ther Med. 2016;11:1947-1954 pubmed
  • western blot; rat; 1:500; fig 5
Li Y, Liu J, Gao D, Wei J, Yuan H, Niu X, et al. Age-related changes in hypertensive brain damage in the hippocampi of spontaneously hypertensive rats. Mol Med Rep. 2016;13:2552-60 pubmed publisher
  • western blot; mouse; 1:100; fig 8
Sabogal Guáqueta A, Osorio E, Cardona Gómez G. Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice. Neuropharmacology. 2016;102:111-20 pubmed publisher
  • immunohistochemistry; mouse; 1:250
Forbes M, Thornhill B, Galarreta C, Chevalier R. A population of mitochondrion-rich cells in the pars recta of mouse kidney. Cell Tissue Res. 2016;363:791-803 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:100
Chugh D, Ali I, Bakochi A, Bahonjic E, Etholm L, Ekdahl C. Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2. PLoS ONE. 2015;10:e0132366 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 5
Sheean R, Weston R, Perera N, D Amico A, Nutt S, Turner B. Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice. J Neuroinflammation. 2015;12:40 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6
Jeon W, Shin I, Shin H, Lee M. Samsoeum water extract attenuates allergic airway inflammation via modulation of Th1/Th2 cytokines and decrease of iNOS expression in asthmatic mice. BMC Complement Altern Med. 2015;15:47 pubmed publisher
  • western blot; rat; 1:200
Wang J, Zhang Q, Zhao L, Li D, Fu Z, Liang L. Down-regulation of PPAR? in the spinal cord contributes to augmented peripheral inflammation and inflammatory hyperalgesia in diet-induced obese rats. Neuroscience. 2014;278:165-78 pubmed publisher
  • western blot; mouse; 1:1000
Chen H, Sohn J, Zhang L, Tian J, Chen S, Bjeldanes L. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in I?B?/MAPK/ERK signaling pathways. Eur J Pharmacol. 2014;724:168-74 pubmed publisher
  • immunohistochemistry; mouse
Martin L, Liu Z, Chen K, Price A, Pan Y, Swaby J, et al. Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. J Comp Neurol. 2007;500:20-46 pubmed
Popovic D, Kocic G, Katic V, Zarubica A, Velickovic L, Ničković V, et al. Anthocyanins Protect Hepatocytes against CCl4-Induced Acute Liver Injury in Rats by Inhibiting Pro-inflammatory mediators, Polyamine Catabolism, Lipocalin-2, and Excessive Proliferation of Kupffer Cells. Antioxidants (Basel). 2019;8: pubmed publisher
Liu M, Yin L, Li W, Hu J, Wang H, Ye B, et al. C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction. J Cell Physiol. 2019;234:18731-18747 pubmed publisher
Sugiyama Y, Hiraiwa Y, Hagiya Y, Nakajima M, Tanaka T, Ogura S. 5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages. BMC Immunol. 2018;19:41 pubmed publisher
Meng J, Zhou C, Hu B, Luo M, Yang Y, Wang Y, et al. Stevioside Prevents Wear Particle-Induced Osteolysis by Inhibiting Osteoclastogenesis and Inflammatory Response via the Suppression of TAK1 Activation. Front Pharmacol. 2018;9:1053 pubmed publisher
Cabral G, Wang Z, Sibley L, DaMatta R. Inhibition of Nitric Oxide Production in Activated Macrophages Caused by Toxoplasma gondii Infection Occurs by Distinct Mechanisms in Different Mouse Macrophage Cell Lines. Front Microbiol. 2018;9:1936 pubmed publisher
Higashi Y, Shimizu T, Yamamoto M, Tanaka K, Yawata T, Shimizu S, et al. Stimulation of brain nicotinic acetylcholine receptors activates adrenomedullary outflow via brain inducible NO synthase-mediated S-nitrosylation. Br J Pharmacol. 2018;175:3758-3772 pubmed publisher
Feng J, Wickenhagen A, Turnbull M, Rezelj V, Kreher F, Tilston Lunel N, et al. Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20. J Virol. 2018;92: pubmed publisher
Neal M, Boyle A, Budge K, Safadi F, Richardson J. The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor. J Neuroinflammation. 2018;15:73 pubmed publisher
Lee H, Lim S, Lee H, Yoo H, Kim H. Yuk-Mi-Jihwang-Tang, a Traditional Korean Multiple Herbal Formulae, Improves Hippocampal Memory on Scopolamine Injection-Induced Amnesia Model of C57BL/6 Mice. Evid Based Complement Alternat Med. 2018;2018:2821040 pubmed publisher
Isidro R, Lopez A, Cruz M, Gonzalez Torres M, Chompré G, Isidro A, et al. The Probiotic VSL#3 Modulates Colonic Macrophages, Inflammation, and Microflora in Acute Trinitrobenzene Sulfonic Acid Colitis. J Histochem Cytochem. 2017;65:445-461 pubmed publisher
Li Y, Zhang Y, Wang L, Wang P, Xue Y, Li X, et al. Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia. Autophagy. 2017;13:1145-1160 pubmed publisher
Choudhury M, Saha N. Induction of Inducible Nitric Oxide Synthase by Lipopolysaccharide and the Influences of Cell Volume Changes, Stress Hormones and Oxidative Stress on Nitric Oxide Efflux from the Perfused Liver of Air-Breathing Catfish, Heteropneustes fossilis. PLoS ONE. 2016;11:e0150469 pubmed publisher
Kurkó J, Vida A, Ocskó T, Tryniszewska B, Rauch T, Glant T, et al. Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow. PLoS ONE. 2014;9:e111815 pubmed publisher
Liu Y, Tipoe G, Fung M. Melatonin attenuates intermittent hypoxia-induced lipid peroxidation and local inflammation in rat adrenal medulla. Int J Mol Sci. 2014;15:18437-52 pubmed publisher
Cheng S, LeBlanc K, Li L. Triptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's disease. PLoS ONE. 2014;9:e108845 pubmed publisher
Winston J, Chen J, Shi X, Sarna S. Inflammation induced by mast cell deficiency rather than the loss of interstitial cells of Cajal causes smooth muscle dysfunction in W/W(v) mice. Front Physiol. 2014;5:22 pubmed publisher
Gülçubuk A, Haktanir D, Cakiris A, Ustek D, Guzel O, Erturk M, et al. Effects of curcumin on proinflammatory cytokines and tissue injury in the early and late phases of experimental acute pancreatitis. Pancreatology. 2013;13:347-54 pubmed publisher
Jiang T, Gao L, Shi J, Lu J, Wang Y, Zhang Y. Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats. Pharmacol Res. 2013;67:84-93 pubmed publisher
Rosique M, Rosique R, Tirapelli L, Joviliano E, Dalio M, Bassetto S, et al. Effects of elevated perfusion pressure and pulsatile flow on human saphenous veins isolated from diabetic and non-diabetic patients. Diab Vasc Dis Res. 2013;10:246-55 pubmed publisher
Tsay T, Yang M, Chen P, Lin C, Hsu C, Chen L. TNF-alpha decreases infection-induced lung injury in burn through negative regulation of TLR4/iNOS. J Surg Res. 2013;179:106-14 pubmed publisher
De Vocht N, Lin D, Praet J, Hoornaert C, Reekmans K, Le Blon D, et al. Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain. Immunobiology. 2013;218:696-705 pubmed publisher
Choudhury M, Saha N. Expression of inducible nitric oxide synthase and nitric oxide production in the mud-dwelled air-breathing singhi catfish, Heteropneustes fossilis under condition of water shortage. Nitric Oxide. 2012;27:219-27 pubmed publisher
Choudhury M, Saha N. Influence of environmental ammonia on the production of nitric oxide and expression of inducible nitric oxide synthase in the freshwater air-breathing catfish (Heteropneustes fossilis). Aquat Toxicol. 2012;116-117:43-53 pubmed publisher
Charpentier C, Marion Letellier R, Savoye G, Nicol L, Mulder P, Aziz M, et al. Magnetic resonance colonography in rats with TNBS-induced colitis: a feasibility and validation study. Inflamm Bowel Dis. 2012;18:1940-9 pubmed publisher
Yin H, Shi Z, Yu Y, Hu J, Wang R, Luan Z, et al. Protection against osteoporosis by statins is linked to a reduction of oxidative stress and restoration of nitric oxide formation in aged and ovariectomized rats. Eur J Pharmacol. 2012;674:200-6 pubmed publisher
De Benedictis L, Potenza M, Gagliardi S, Zigrino A, Montagnani M, De Salvia M. Rosiglitazone reverses increased duodenal inhibitory response in spontaneously hypertensive rats. Neurogastroenterol Motil. 2012;24:e56-66 pubmed publisher
Yoshino Y, Yamamoto S, Kohsaka S, Oshiro S, Nakajima K. Superoxide anion contributes to the induction of tumor necrosis factor alpha (TNF?) through activation of the MKK3/6-p38 MAPK cascade in rat microglia. Brain Res. 2011;1422:1-12 pubmed publisher
Omri S, Behar Cohen F, de Kozak Y, Sennlaub F, Verissimo L, Jonet L, et al. Microglia/macrophages migrate through retinal epithelium barrier by a transcellular route in diabetic retinopathy: role of PKC? in the Goto Kakizaki rat model. Am J Pathol. 2011;179:942-53 pubmed publisher
Suman S, Seth R, Chandna S. A calcium-insensitive attenuated nitrosative stress response contributes significantly in the radioresistance of Sf9 insect cells. Int J Biochem Cell Biol. 2011;43:1340-53 pubmed publisher
Ratovitski E. ?Np63?/IRF6 interplay activates NOS2 transcription and induces autophagy upon tobacco exposure. Arch Biochem Biophys. 2011;506:208-15 pubmed publisher
PFISTER S, Somberg L, Lowry T, Gao Y, Medhora M, Jacobs E. Mechanisms underlying increased reactivity of pulmonary arteries contralateral to a localized high-flow anastomosis. J Thorac Cardiovasc Surg. 2011;141:425-31 pubmed publisher
Bhaskaran N, Shukla S, Srivastava J, Gupta S. Chamomile: an anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity. Int J Mol Med. 2010;26:935-40 pubmed
Tonelli R, Torrecilhas A, Jacysyn J, Juliano M, Colli W, Alves M. In vivo infection by Trypanosoma cruzi: the conserved FLY domain of the gp85/trans-sialidase family potentiates host infection. Parasitology. 2011;138:481-92 pubmed publisher
Capellini V, Baldo C, Celotto A, Batalhão M, Carnio E, Rodrigues A, et al. Oxidative stress is not associated with vascular dysfunction in a model of alloxan-induced diabetic rats. Arq Bras Endocrinol Metabol. 2010;54:530-9 pubmed
LaLone C, Huang N, Rizshsky L, Yum M, Singh N, Hauck C, et al. Enrichment of Echinacea angustifolia with Bauer alkylamide 11 and Bauer ketone 23 increased anti-inflammatory potential through interference with cox-2 enzyme activity. J Agric Food Chem. 2010;58:8573-84 pubmed publisher
Kim J, Kim O, Kim C, Kim N, Kim J. Cytotoxic role of methylglyoxal in rat retinal pericytes: Involvement of a nuclear factor-kappaB and inducible nitric oxide synthase pathway. Chem Biol Interact. 2010;188:86-93 pubmed publisher
Miranda L, Capellini V, Reis G, Celotto A, Carlotti C, Evora P. Effects of partial liver ischemia followed by global liver reperfusion on the remote tissue expression of nitric oxide synthase: lungs and kidneys. Transplant Proc. 2010;42:1557-62 pubmed publisher
Zheng B, Zheng T, Wang L, Chen X, Shi C, Zhao S. Aminoguanidine inhibition of iNOS activity ameliorates cerebral vasospasm after subarachnoid hemorrhage in rabbits via restoration of dysfunctional endothelial cells. J Neurol Sci. 2010;295:97-103 pubmed publisher
Tanaka S, Tsutsui M, Kishida T, Souma S, Kuroda J, Yoshida T. Salbutamol inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal macrophages. J Toxicol Sci. 2010;35:327-34 pubmed
Broderick T, Wang Y, Gutkowska J, Wang D, Jankowski M. Downregulation of oxytocin receptors in right ventricle of rats with monocrotaline-induced pulmonary hypertension. Acta Physiol (Oxf). 2010;200:147-58 pubmed publisher
Viaro F, Capellini V, Celotto A, Carlotti C, Rodrigues A, Reis G, et al. Immunohistochemical evaluation of three nitric oxide synthase isoforms in human saphenous vein exposed to different degrees of distension pressures. Cardiovasc Pathol. 2010;19:e211-20 pubmed publisher
Ryu B, Qian Z, Kim S. Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-kappaB activation, and induces human osteoblastic and chondrocytic differentiation. Chem Biol Interact. 2010;184:413-22 pubmed publisher
Huang N, Hauck C, Yum M, Rizshsky L, Widrlechner M, McCoy J, et al. Rosmarinic acid in Prunella vulgaris ethanol extract inhibits lipopolysaccharide-induced prostaglandin E2 and nitric oxide in RAW 264.7 mouse macrophages. J Agric Food Chem. 2009;57:10579-89 pubmed publisher
Chen K, Northington F, Martin L. Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice. Brain Struct Funct. 2010;214:219-34 pubmed publisher
Demarco V, Habibi J, Whaley Connell A, Schneider R, Sowers J, Andresen B, et al. Rosuvastatin ameliorates the development of pulmonary arterial hypertension in the transgenic (mRen2)27 rat. Am J Physiol Heart Circ Physiol. 2009;297:H1128-39 pubmed publisher
Dhar S, Liang H, Wong Riley M. Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c oxidase genes in neurons. Biochim Biophys Acta. 2009;1793:1604-13 pubmed publisher
Elahi M, Worner M, Khan J, Matata B. Inspired nitric oxide and modulation of oxidative stress during cardiac surgery. Curr Drug Saf. 2009;4:188-98 pubmed
La Rocca G, Di Stefano A, Eleuteri E, Anzalone R, Magno F, Corrao S, et al. Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure. Basic Res Cardiol. 2009;104:307-20 pubmed publisher
Grasa L, Arruebo M, Plaza M, Murillo M. A downregulation of nNOS is associated to dysmotility evoked by lipopolysaccharide in rabbit duodenum. J Physiol Pharmacol. 2008;59:511-24 pubmed
Magrone T, Tafaro A, Jirillo F, Panaro M, Cuzzuol P, Cuzzuol A, et al. Red wine consumption and prevention of atherosclerosis: an in vitro model using human peripheral blood mononuclear cells. Curr Pharm Des. 2007;13:3718-25 pubmed
Engebretsen B, Irwin D, Valdez M, O Donovan M, Tucker A, van Patot M. Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats. High Alt Med Biol. 2007;8:312-21 pubmed
Aguilera P, Chánez Cárdenas M, Floriano Sánchez E, Barrera D, Santamaria A, Sánchez González D, et al. Time-related changes in constitutive and inducible nitric oxide synthases in the rat striatum in a model of Huntington's disease. Neurotoxicology. 2007;28:1200-7 pubmed
Zelcer N, Khanlou N, Clare R, Jiang Q, Reed Geaghan E, Landreth G, et al. Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proc Natl Acad Sci U S A. 2007;104:10601-6 pubmed
Medeiros R, Prediger R, Passos G, Pandolfo P, Duarte F, Franco J, et al. Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein. J Neurosci. 2007;27:5394-404 pubmed
Moraes J, Amaral M, Picardi P, Calegari V, Romanatto T, Bermúdez Echeverry M, et al. Inducible-NOS but not neuronal-NOS participate in the acute effect of TNF-alpha on hypothalamic insulin-dependent inhibition of food intake. FEBS Lett. 2006;580:4625-31 pubmed
Montes S, Perez Severiano F, Vergara P, Segovia J, Rios C, Muriel P. Nitric oxide production in striatum and pallidum of cirrhotic rats. Neurochem Res. 2006;31:11-20 pubmed
Lazzarini R, Maiorka P, Liu J, Papadopoulos V, Palermo Neto J. Diazepam effects on carrageenan-induced inflammatory paw edema in rats: role of nitric oxide. Life Sci. 2006;78:3027-34 pubmed
Feng C, Wang L, Jiao L, Liu B, Zheng S, Xie X. Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features. BMC Cancer. 2002;2:8 pubmed
product information
Product Name :
NOS2 (C-11) Antibody
Gene Name :
NOS2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7271
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
NOS2
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
C-terminal (m)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA