product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Trk (B-3) Antibody
catalog :
sc-7268
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-3
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 1B
  • proximity ligation assay; rat; fig 5A
Canu N, Pagano I, La Rosa L, Pellegrino M, Ciotti M, Mercanti D, et al. Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents. Front Mol Neurosci. 2017;10:15 pubmed publisher
  • immunoprecipitation; mouse; fig 4
  • western blot; mouse; 1:1000; fig 4
Triaca V, Sposato V, Bolasco G, Ciotti M, Pelicci P, Bruni A, et al. NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease. Aging Cell. 2016;15:661-72 pubmed publisher
Crerar H, Scott Solomon E, Bodkin Clarke C, Andreassi C, Hazbon M, Logie E, et al. Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019;102:553-563.e8 pubmed publisher
Brito V, Puigdellivol M, Giralt A, Del Toro D, Alberch J, Gines S. Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies. Cell Death Dis. 2013;4:e595 pubmed publisher
Schonemann M, Muench M, Tee M, Miller W, Mellon S. Expression of P450c17 in the human fetal nervous system. Endocrinology. 2012;153:2494-505 pubmed publisher
Gines S, Paoletti P, Alberch J. Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression. J Biol Chem. 2010;285:21537-48 pubmed publisher
Wong A, Willingham M, Xiao J, Kilpatrick T, Murray S. Neurotrophin receptor homolog-2 regulates nerve growth factor signaling. J Neurochem. 2008;106:1964-76 pubmed publisher
Voss O, Milne S, Sharkey J, O Neill M, McCulloch J. Molecular mechanisms of neurite growth with AMPA receptor potentiation. Neuropharmacology. 2007;52:590-7 pubmed
Gines S, Bosch M, Marco S, Gavalda N, Diaz Hernandez M, Lucas J, et al. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain. Eur J Neurosci. 2006;23:649-58 pubmed
Teng H, Teng K, Lee R, Wright S, Tevar S, Almeida R, et al. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci. 2005;25:5455-63 pubmed
Rihl M, Kruithof E, Barthel C, De Keyser F, Veys E, Zeidler H, et al. Involvement of neurotrophins and their receptors in spondyloarthritis synovitis: relation to inflammation and response to treatment. Ann Rheum Dis. 2005;64:1542-9 pubmed
product information
Product Name :
Trk (B-3) Antibody
Gene Name :
NTRK1, NTRK2, NTRK3
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-7268
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Trk
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
C-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA