This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
IGF-IRbeta (C-20)
catalog :
sc-713
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; fig 1
  • western blot; mouse; fig 1
Li L, Byrd M, Doh K, Dixon P, Lee H, Tiwari S, et al. Absence of renal enlargement in fructose-fed proximal-tubule-select insulin receptor (IR), insulin-like-growth factor receptor (IGF1R) double knockout mice. Physiol Rep. 2016;4: pubmed
  • western blot; human; 1:1000; loading ...; fig 5a
Boo H, Min H, Jang H, Yun H, Smith J, Jin Q, et al. The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun. 2016;7:12961 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Bassi D, Zhang J, Renner C, Klein Szanto A. Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth. Mol Carcinog. 2017;56:1182-1188 pubmed publisher
Wang M, LAW M, Davis B, Yaaghubi E, Ghilardi A, Ferreira R, et al. Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway. Cell Death Discov. 2019;5:153 pubmed publisher
Zhou T, Zhu T, Rivera J, Omri S, Tahiri H, Lahaie I, et al. The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity. Am J Pathol. 2019;189:2340-2356 pubmed publisher
Delcroix V, Mauduit O, Tessier N, Montillaud A, Lesluyes T, Ducret T, et al. The Role of the Anti-Aging Protein Klotho in IGF-1 Signaling and Reticular Calcium Leak: Impact on the Chemosensitivity of Dedifferentiated Liposarcomas. Cancers (Basel). 2018;10: pubmed publisher
Ratcliffe L, Vázquez Villaseñor I, Jennings L, Heath P, Mortiboys H, Schwartzentruber A, et al. Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons. Neuroscience. 2018;390:46-59 pubmed publisher
Gubbiotti M, Seifert E, Rodeck U, Hoek J, Iozzo R. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. J Biol Chem. 2018;293:16940-16950 pubmed publisher
Rizzolio S, Cagnoni G, Battistini C, Bonelli S, Isella C, Van Ginderachter J, et al. Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies. J Clin Invest. 2018;128:3976-3990 pubmed publisher
Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, et al. IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling. elife. 2018;7: pubmed publisher
Lyons A, Coleman M, Riis S, Favre C, O Flanagan C, Zhdanov A, et al. Insulin-like growth factor 1 signaling is essential for mitochondrial biogenesis and mitophagy in cancer cells. J Biol Chem. 2017;292:16983-16998 pubmed publisher
Rodríguez Barrueco R, Nekritz E, Bertucci F, Yu J, Sanchez Garcia F, Zeleke T, et al. miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy. Genes Dev. 2017;31:553-566 pubmed publisher
Muranen T, Iwanicki M, Curry N, Hwang J, DuBois C, Coloff J, et al. Starved epithelial cells uptake extracellular matrix for survival. Nat Commun. 2017;8:13989 pubmed publisher
Sayeed A, Lu H, Liu Q, Deming D, Duffy A, McCue P, et al. ?1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation. Oncotarget. 2016;7:52618-52630 pubmed publisher
Periyasamy Thandavan S, Takhar S, Singer A, Dohn M, Jackson W, Welborn A, et al. Insulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER+ breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein Bim. Breast Cancer Res. 2012;14:R52 pubmed
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA