product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HSP 90 (4F10) Antibody
catalog :
sc-69703
quantity :
50 µg/0.5 ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4F10
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 32
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 4c
Xie Y, Fan H, Lu W, Yang Q, Nurkesh A, Yeleussizov T, et al. Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer. Oncogene. 2019;38:2967-2983 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3i
Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
  • western blot; human; loading ...; fig 3e
Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, et al. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Res. 2017;45:3738-3751 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s6a
Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed publisher
  • western blot; human; loading ...; fig 2a
Fritsch J, Fickers R, Klawitter J, Särchen V, Zingler P, Adam D, et al. TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death. Oncotarget. 2016;7:75774-75789 pubmed publisher
  • western blot; human; loading ...; fig 3c
Trousil S, Kaliszczak M, Schug Z, Nguyen Q, Tomasi G, Favicchio R, et al. The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth. Oncotarget. 2016;7:37103-37120 pubmed publisher
  • western blot; human; loading ...; fig 1a
Mariani S, Minieri V, De Dominici M, Iacobucci I, Peterson L, Calabretta B. CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia. Leukemia. 2016;30:1682-90 pubmed publisher
  • western blot; human; fig 6
Beaumatin F, El Dhaybi M, Lasserre J, Salin B, Moyer M, Verdier M, et al. N52 monodeamidated Bcl‑xL shows impaired oncogenic properties in vivo and in vitro. Oncotarget. 2016;7:17129-43 pubmed publisher
  • western blot; human; 1:2000; fig 1
Habiger C, Jäger G, Walter M, Iftner T, Stubenrauch F. Interferon Kappa Inhibits Human Papillomavirus 31 Transcription by Inducing Sp100 Proteins. J Virol. 2016;90:694-704 pubmed publisher
  • western blot; human
Kuo P, Huang C, Lee C, Chang H, Hsieh S, Chung Y, et al. BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability. Br J Cancer. 2015;112:391-402 pubmed publisher
  • immunocytochemistry; human; 1:50
  • western blot; human
Munday D, Wu W, Smith N, Fix J, Noton S, Galloux M, et al. Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis. J Virol. 2015;89:917-30 pubmed publisher
  • western blot; human; fig s3d
Hamilton G, Abraham A, Morton J, Sampson O, Pefani D, Khoronenkova S, et al. AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Oncotarget. 2014;5:6142-67 pubmed
  • western blot; human
Hamouda M, Belhacene N, Puissant A, Colosetti P, Robert G, Jacquel A, et al. The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells. Oncotarget. 2014;5:6252-66 pubmed
  • immunocytochemistry; human; 1:200
Liu Y, Jiang Y, Wang B, Hao J, Shang L, Zhang T, et al. A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens. Cancer Cytopathol. 2014;122:833-41 pubmed publisher
  • western blot; human
Lee J, Kim W, Gygi S, Ye Y. Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation. J Biol Chem. 2014;289:3510-7 pubmed publisher
Yigitliler A, Renner J, Simon C, Schneider M, Stubenrauch F, Iftner T. BRD4S interacts with viral E2 protein to limit human papillomavirus late transcription. J Virol. 2021;: pubmed publisher
Rawson J, Duchon A, Nikolaitchik O, Pathak V, HU W. Development of a Cell-Based Luciferase Complementation Assay for Identification of SARS-CoV-2 3CLpro Inhibitors. Viruses. 2021;13: pubmed publisher
Kabir S, Cidado J, Andersen C, Dick C, Lin P, Mitros T, et al. The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells. elife. 2019;8: pubmed publisher
Schneider M, Yigitliler A, Stubenrauch F, Iftner T. Cottontail Rabbit Papillomavirus E1 and E2 Proteins Mutually Influence Their Subcellular Localizations. J Virol. 2018;92: pubmed publisher
Luciano A, Zhou W, Santana J, Kyriakides C, Velazquez H, Sessa W. CLOCK phosphorylation by AKT regulates its nuclear accumulation and circadian gene expression in peripheral tissues. J Biol Chem. 2018;293:9126-9136 pubmed publisher
Kaisari S, Sitry Shevah D, Miniowitz Shemtov S, Teichner A, Hershko A. Role of CCT chaperonin in the disassembly of mitotic checkpoint complexes. Proc Natl Acad Sci U S A. 2017;114:956-961 pubmed publisher
Thinon E, Morales Sanfrutos J, Mann D, Tate E. N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells. ACS Chem Biol. 2016;11:2165-76 pubmed publisher
Dreer M, Fertey J, van de Poel S, Straub E, Madlung J, Macek B, et al. Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication. PLoS Pathog. 2016;12:e1005556 pubmed publisher
Caligiuri I, Toffoli G, Giordano A, Rizzolio F. pRb controls estrogen receptor alpha protein stability and activity. Oncotarget. 2013;4:875-83 pubmed
Gao B, Wang Y, Xu W, Li S, Li Q, Xiong S. Inhibition of histone deacetylase activity suppresses IFN-? induction of tripartite motif 22 via CHIP-mediated proteasomal degradation of IRF-1. J Immunol. 2013;191:464-71 pubmed publisher
Zhou Z, Xie X, Zhou S, Li C. Mechanism of reversal of high glucose-induced endothelial nitric oxide synthase uncoupling by tanshinone IIA in human endothelial cell line EA.hy926. Eur J Pharmacol. 2012;697:97-105 pubmed publisher
Reebye V, Querol Cano L, Lavery D, Brooke G, Powell S, Chotai D, et al. Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancer. Mol Endocrinol. 2012;26:1694-706 pubmed
Hamelin C, Cornut E, Poirier F, Pons S, Beaulieu C, Charrier J, et al. Identification and verification of heat shock protein 60 as a potential serum marker for colorectal cancer. FEBS J. 2011;278:4845-59 pubmed publisher
Reiser J, Hurst J, Voges M, Krauss P, Münch P, Iftner T, et al. High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression. J Virol. 2011;85:11372-80 pubmed publisher
Fertey J, Hurst J, Straub E, Schenker A, Iftner T, Stubenrauch F. Growth inhibition of HeLa cells is a conserved feature of high-risk human papillomavirus E8^E2C proteins and can also be achieved by an artificial repressor protein. J Virol. 2011;85:2918-26 pubmed publisher
Bae Y, Alani A, Rockich N, Lai T, Kwon G. Mixed pH-sensitive polymeric micelles for combination drug delivery. Pharm Res. 2010;27:2421-32 pubmed publisher
Huang M, Wei J, Peng W, Liang J, Zhao C, Qian Y, et al. The association of CaM and Hsp70 regulates S-phase arrest and apoptosis in a spatially and temporally dependent manner in human cells. Cell Stress Chaperones. 2009;14:343-53 pubmed publisher
product information
Catalog Number :
sc-69703
Product Name :
HSP 90 (4F10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
4F10
Isotype :
IgG2b
Size :
50 µg/0.5 ml
List Price :
316 USD
Immunogen :
HSP 90
Specificity :
human
Uses :
WB, IP, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA