product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
c-Rel (B-6) Antibody
catalog :
sc-6955
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:100; fig 9
Lindholm P, Sivapurapu N, Jovanovic B, Kajdacsy-Balla A. Monocyte-Induced Prostate Cancer Cell Invasion is Mediated by Chemokine ligand 2 and Nuclear Factor-κB Activity. J Clin Cell Immunol. 2015;6: pubmed
  • western blot; human
Dutta J, Fan G, Gelinas C. CAPERalpha is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-kappaB oncoprotein v-Rel. J Virol. 2008;82:10792-802 pubmed publisher
Yang H, Kim J, Lee K, Jang Y. Rac/ROS-related protein kinase C and phosphatidylinositol-3-kinase signaling are involved in a negative regulating cascade in B cell activation by antibody-mediated cross-linking of MHC class II molecules. Mol Immunol. 2010;47:706-12 pubmed publisher
Lessard L, Saad F, Le Page C, Diallo J, Péant B, Delvoye N, et al. NF-kappaB2 processing and p52 nuclear accumulation after androgenic stimulation of LNCaP prostate cancer cells. Cell Signal. 2007;19:1093-100 pubmed
Dahlman J, Guttridge D. Detection of NF-κB activity in skeletal muscle cells by electrophoretic mobility shift analysis. Methods Mol Biol. 2012;798:505-16 pubmed publisher
Bellarosa D, Binaschi M, Maggi C, Goso C. Sabarubicin- (MEN 10755) and paclitaxel show different kinetics in nuclear factor-kappaB (NF-kB) activation: effect of parthenolide on their cytotoxicity. Anticancer Res. 2005;25:2119-28 pubmed
Dieckhoff K, Graf P, Beinhauer B, Schwaerzler C, Carballido J, Neumann C, et al. Deficient translocation of c-Rel is associated with impaired Th1 cytokine production in T cells from atopic dermatitis patients. Exp Dermatol. 2005;14:17-25 pubmed
Coupienne I, Piette J, Bontems S. How to monitor NF-kappaB activation after photodynamic therapy. Methods Mol Biol. 2010;635:79-95 pubmed publisher
Mihalcik S, Huddleston P, Wu X, Jelinek D. The structure of the TNFRSF13C promoter enables differential expression of BAFF-R during B cell ontogeny and terminal differentiation. J Immunol. 2010;185:1045-54 pubmed publisher
Noonan E, Giardina C, Hightower L. Hsp70B' and Hsp72 form a complex in stressed human colon cells and each contributes to cytoprotection. Exp Cell Res. 2008;314:2468-76 pubmed publisher
Souvannavong V, Saidji N, Chaby R. Lipopolysaccharide from Salmonella enterica activates NF-kappaB through both classical and alternative pathways in primary B Lymphocytes. Infect Immun. 2007;75:4998-5003 pubmed
Cardoso F, Durbecq V, Laes J, Badran B, Lagneaux L, Bex F, et al. Bortezomib (PS-341, Velcade) increases the efficacy of trastuzumab (Herceptin) in HER-2-positive breast cancer cells in a synergistic manner. Mol Cancer Ther. 2006;5:3042-51 pubmed
Sermeus A, Cosse J, Crespin M, Mainfroid V, de Longueville F, Ninane N, et al. Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity. Mol Cancer. 2008;7:27 pubmed publisher
Gregory D, Godbout M, Contreras I, Forget G, Olivier M. A novel form of NF-kappaB is induced by Leishmania infection: involvement in macrophage gene expression. Eur J Immunol. 2008;38:1071-81 pubmed publisher
Mukhopadhyay N, Ferdinand A, Mukhopadhyay L, Cinar B, Lutchman M, Richie J, et al. Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor. Exp Cell Res. 2006;312:3782-95 pubmed
Yang H, Kim J, Kim S, Choe C, Jang Y. Pro-IL-16 is associated with MHC class II-mediated negative regulation of mouse resting B cell activation through MAP kinases, NF-κB and Skp2-dependent p27kip regulation. Scand J Immunol. 2013;77:177-86 pubmed publisher
Salvatore C, Camarda G, Maggi C, Goso C, Manzini S, Binaschi M. NF-kappaB activation contributes to anthracycline resistance pathway in human ovarian carcinoma cell line A2780. Int J Oncol. 2005;27:799-806 pubmed
Nakanishi H, Groskopf J, Fritsche H, Bhadkamkar V, Blase A, Kumar S, et al. PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates for active surveillance. J Urol. 2008;179:1804-9; discussion 1809-10 pubmed publisher
Burstein E, Hoberg J, Wilkinson A, Rumble J, Csomos R, Komarck C, et al. COMMD proteins, a novel family of structural and functional homologs of MURR1. J Biol Chem. 2005;280:22222-32 pubmed
Zdanov S, Bernard D, Debacq-Chainiaux F, Martien S, Gosselin K, Vercamer C, et al. Normal or stress-induced fibroblast senescence involves COX-2 activity. Exp Cell Res. 2007;313:3046-56 pubmed
Zhao X, Zhang Y, Strong R, Zhang J, Grotta J, Aronowski J. Distinct patterns of intracerebral hemorrhage-induced alterations in NF-kappaB subunit, iNOS, and COX-2 expression. J Neurochem. 2007;101:652-63 pubmed
Moore F, Buonocore S, Aksoy E, Ouled-Haddou N, Goriely S, Lazarova E, et al. An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha. J Immunol. 2007;178:1301-11 pubmed
Deruy E, Nassour J, Martin N, Vercamer C, Malaquin N, Bertout J, et al. Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion. Cell Death Dis. 2014;5:e1577 pubmed publisher
Takeiri M, Horie K, Takahashi D, Watanabe M, Horie R, Simizu S, et al. Involvement of DNA binding domain in the cellular stability and importin affinity of NF-κB component RelB. Org Biomol Chem. 2012;10:3053-9 pubmed publisher
Yang H, Kim J, Chung G, Lee J, Jang Y. Cross-linking of MHC class II molecules interferes with phorbol 12,13-dibutyrate-induced differentiation of resting B cells by inhibiting Rac-associated ROS-dependent ERK/p38 MAP kinase pathways leading to NF-kappaB activation. Mol Immunol. 2007;44:1577-86 pubmed
product information
Product Name :
c-Rel (B-6) Antibody
Gene Name :
REL
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-6955
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
c-Rel
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
1-300 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA