product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
TRAF3 (G-6) Antibody
catalog :
sc-6933
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G-6
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, western blot knockout validation, immunocytochemistry knockout validation
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; mouse; loading ...; fig 2d
  • western blot knockout validation; mouse; 1:750; loading ...; fig 2a
Fomicheva M, Macara I. Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig s9c
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, et al. Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation. Nat Commun. 2019;10:1801 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 6d
  • western blot; mouse; loading ...; fig 5a
Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 6b
  • western blot; human; loading ...; fig 6a
Ma C, Lin W, Liu Z, Tang W, Gautam R, Li H, et al. NDR1 protein kinase promotes IL-17- and TNF-α-mediated inflammation by competitively binding TRAF3. EMBO Rep. 2017;18:586-602 pubmed publisher
  • western blot; human; loading ...; fig 5c
Cai B, Wu J, Yu X, Su X, Wang R. FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions. MBio. 2017;8: pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Huai W, Song H, Yu Z, Wang W, Han L, Sakamoto T, et al. Mint3 potentiates TLR3/4- and RIG-I-induced IFN-? expression and antiviral immune responses. Proc Natl Acad Sci U S A. 2016;113:11925-11930 pubmed
Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed publisher
Shinzawa M, Konno H, Qin J, Akiyama N, Miyauchi M, Ohashi H, et al. Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression. Sci Rep. 2015;5:10758 pubmed publisher
Shih V, Davis Turak J, Macal M, Huang J, Ponomarenko J, Kearns J, et al. Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-?B pathways. Nat Immunol. 2012;13:1162-70 pubmed publisher
Farhana L, Dawson M, Murshed F, Fontana J. Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-?B noncanonical and canonical pathway activation. Cell Death Differ. 2011;18:164-73 pubmed publisher
Nakhaei P, Mesplede T, Solis M, Sun Q, Zhao T, Yang L, et al. The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation. PLoS Pathog. 2009;5:e1000650 pubmed publisher
product information
Product Name :
TRAF3 (G-6) Antibody
Gene Name :
TRAF3
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-6933
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
TRAF3
reactive species  :
m, r, h
Application :
WB, IP, IF, FCM
Epitope :
322-444 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA