product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GADD 45alpha (C-4) Antibody
catalog :
sc-6850
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-4
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:100; loading ...; fig 2d
Loureiro J, Raimundo L, Calheiros J, Carvalho C, Barcherini V, Lima N, et al. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers (Basel). 2021;13: pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4
  • western blot; human; 1:200; fig 4
Wu T, Li Y, Liu B, Zhang S, Wu L, Zhu X, et al. Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway. PLoS ONE. 2016;11:e0149361 pubmed publisher
  • western blot; human
Xiu P, Xu Z, Liu F, Li Z, Li T, Zou F, et al. Downregulating sCLU enhances the sensitivity of hepatocellular carcinoma cells to gemcitabine by activating the intrinsic apoptosis pathway. Dig Dis Sci. 2014;59:1798-809 pubmed publisher
  • western blot; human
Lau R, Niu M, Pratt M. cIAP2 represses IKK?/?-mediated activation of MDM2 to prevent p53 degradation. Cell Cycle. 2012;11:4009-19 pubmed publisher
  • western blot; human
Dolezalova D, Mraz M, Bárta T, Plevova K, Vinarsky V, Holubcová Z, et al. MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells. Stem Cells. 2012;30:1362-72 pubmed publisher
Takwi A, Li Y, Becker Buscaglia L, Zhang J, Choudhury S, Park A, et al. A statin-regulated microRNA represses human c-Myc expression and function. EMBO Mol Med. 2012;4:896-909 pubmed publisher
Salerno D, Tront J, Hoffman B, Liebermann D. Gadd45a and Gadd45b modulate innate immune functions of granulocytes and macrophages by differential regulation of p38 and JNK signaling. J Cell Physiol. 2012;227:3613-20 pubmed publisher
Xu K, Zhou Y, Qiu W, Liu X, Xia M, Liu L, et al. Activating transcription factor 3 (ATF3) promotes sublytic C5b-9-induced glomerular mesangial cells apoptosis through up-regulation of Gadd45? and KLF6 gene expression. Immunobiology. 2011;216:871-81 pubmed publisher
Perisic T, Zimmermann N, Kirmeier T, Asmus M, Tuorto F, Uhr M, et al. Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes. Neuropsychopharmacology. 2010;35:792-805 pubmed publisher
Gionet N, Jansson D, Mader S, Pratt M. NF-kappaB and estrogen receptor alpha interactions: Differential function in estrogen receptor-negative and -positive hormone-independent breast cancer cells. J Cell Biochem. 2009;107:448-59 pubmed publisher
Machida S, Booth F. Changes in signalling molecule levels in 10-day hindlimb immobilized rat muscles. Acta Physiol Scand. 2005;183:171-9 pubmed
product information
Product Name :
GADD 45alpha (C-4) Antibody
Gene Name :
GADD45A
Size :
200 µg/ml
Catalog Number :
sc-6850
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
GADD 45alpha
reactive species  :
m, r, h
Application :
WB, IP, IF, FCM, ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA