product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Endomucin (V.7C7) Antibody
catalog :
sc-65495
quantity :
200 µg/ml
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
V.7C7
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 53
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 3c
Zhang X, Wang Z, Xu Q, Chen Y, Liu W, Zhong T, et al. Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium. iScience. 2021;24:103097 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 7d
Shen J, Sun Y, Liu X, Zhu Y, Bao B, Gao T, et al. EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling. Stem Cell Res Ther. 2021;12:415 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 7d
Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed publisher
  • immunohistochemistry; mouse; 1:50; fig 2e
Sun Q, Zhen G, LI T, Guo Q, Li Y, Su W, et al. Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2s
Tai Nagara I, Hasumi Y, Kusumoto D, Hasumi H, Okabe K, Ando T, et al. Blood and lymphatic systems are segregated by the FLCN tumor suppressor. Nat Commun. 2020;11:6314 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6g
Mia M, Cibi D, Abdul Ghani S, Song W, Tee N, Ghosh S, et al. YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction. PLoS Biol. 2020;18:e3000941 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 1d, 1s2a
Manils J, Webb L, Howes A, Janzen J, Boeing S, Bowcock A, et al. CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5e
Zhong L, Yao L, Tower R, Wei Y, Miao Z, Park J, et al. Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 1d
  • immunohistochemistry; mouse; 1:50; loading ...; fig 5b
Yang M, Li C, Xiao Y, Guo Q, Huang Y, Su T, et al. Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation. Cell Prolif. 2020;53:e12784 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1h, 3s3b
Sivaraj K, Dharmalingam B, Mohanakrishnan V, Jeong H, Kato K, Schröder S, et al. YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig ex3b
Tikhonova A, Dolgalev I, Hu H, Sivaraj K, Hoxha E, Cuesta Dominguez A, et al. The bone marrow microenvironment at single-cell resolution. Nature. 2019;569:222-228 pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; fig 1b
Li L, Kang H, Zhang Q, D Agati V, Al Awqati Q, Lin F. FoxO3 activation in hypoxic tubules prevents chronic kidney disease. J Clin Invest. 2019;129:2374-2389 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s1e
Bartolomé A, Zhu C, Sussel L, Pajvani U. Notch signaling dynamically regulates adult β cell proliferation and maturity. J Clin Invest. 2019;129:268-280 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s1c
Rodríguez Baena F, Redondo García S, Peris Torres C, Martino Echarri E, Fernández Rodríguez R, Plaza Calonge M, et al. ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response. Sci Rep. 2018;8:13103 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig s2a
Chung M, Bujnis M, Barkauskas C, Kobayashi Y, Hogan B. Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. Development. 2018;145: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2b
An Y, Sun K, Joffin N, Zhang F, Deng Y, Donze O, et al. Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis. elife. 2017;6: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 1c
  • immunocytochemistry; mouse; 1:100; loading ...; fig s4b
Reynolds L, D Amico G, Lechertier T, Papachristodoulou A, Muñoz Félix J, De Arcangelis A, et al. Dual role of pericyte ?6?1-integrin in tumour blood vessels. J Cell Sci. 2017;130:1583-1595 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3e
Ubellacker J, Haider M, Decristo M, Allocca G, Brown N, Silver D, et al. Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells. Breast Cancer Res. 2017;19:23 pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; tbl 1
Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 5 ug/ml; fig 6c
Aldabbous L, Abdul Salam V, McKinnon T, Duluc L, Pepke Zaba J, Southwood M, et al. Neutrophil Extracellular Traps Promote Angiogenesis: Evidence From Vascular Pathology in Pulmonary Hypertension. Arterioscler Thromb Vasc Biol. 2016;36:2078-87 pubmed publisher
  • immunohistochemistry; mouse; fig 6
Martin Almedina S, Martínez Corral I, Holdhus R, Vicente A, Fotiou E, Lin S, et al. EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis. J Clin Invest. 2016;126:3080-8 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 4
Regan E, Sibley R, Cenik B, Silva A, Girard L, Minna J, et al. Identification of Gene Expression Differences between Lymphangiogenic and Non-Lymphangiogenic Non-Small Cell Lung Cancer Cell Lines. PLoS ONE. 2016;11:e0150963 pubmed publisher
  • immunohistochemistry; human; 1:1000; fig 1
Zahr A, Alcaide P, Yang J, Jones A, Gregory M, dela Paz N, et al. Endomucin prevents leukocyte-endothelial cell adhesion and has a critical role under resting and inflammatory conditions. Nat Commun. 2016;7:10363 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Norden P, Kim D, Barry D, CLEAVER O, Davis G. Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1. PLoS ONE. 2016;11:e0147758 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig s1a
Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Merk H, Zhang S, Lehr T, Müller C, Ulrich M, Bibb J, et al. Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis. Oncotarget. 2016;7:6088-104 pubmed publisher
  • immunohistochemistry; mouse; fig 4
Zhou Y, Williams J, Smallwood P, Nathans J. Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina. PLoS ONE. 2015;10:e0143650 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6
Haider M, Hunter K, Robinson S, Graham T, Corey E, Dear T, et al. Rapid modification of the bone microenvironment following short-term treatment with Cabozantinib in vivo. Bone. 2015;81:581-92 pubmed publisher
  • immunocytochemistry; mouse; 1:300
Gopinathan G, Milagre C, Pearce O, Reynolds L, Hodivala Dilke K, Leinster D, et al. Interleukin-6 Stimulates Defective Angiogenesis. Cancer Res. 2015;75:3098-107 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4g
Aspelund A, Antila S, Proulx S, Karlsen T, Karaman S, Detmar M, et al. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J Exp Med. 2015;212:991-9 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Liebl J, Zhang S, Moser M, Agalarov Y, Demir C, Hager B, et al. Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 2
Decock J, Hendrickx W, Thirkettle S, Gutiérrez Fernández A, Robinson S, Edwards D. Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice. Breast Cancer Res. 2015;17:38 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
Ye R, Holland W, Gordillo R, Wang M, Wang Q, Shao M, et al. Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration. elife. 2014;3: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1250
Luo Y, Kumar P, Chen C, Latham J, Wang L, Tudela C, et al. Estrogen-related receptor ? serves a role in blood pressure homeostasis during pregnancy. Mol Endocrinol. 2014;28:965-75 pubmed publisher
  • immunohistochemistry; mouse
Dellinger M, Meadows S, Wynne K, Cleaver O, Brekken R. Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS ONE. 2013;8:e74686 pubmed publisher
Fu R, Lv W, Xu Y, Gong M, Chen X, Jiang N, et al. Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosis. Nat Commun. 2020;11:460 pubmed publisher
Yoo H, Lee Y, Park C, Son D, Choi D, Park J, et al. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. Cell Death Dis. 2020;11:14 pubmed publisher
Travisano S, Oliveira V, Prados B, Grego Bessa J, Piñeiro Sabarís R, Bou V, et al. Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. elife. 2019;8: pubmed publisher
Sainz de Aja J, Menchero S, Rollán I, Barral A, Tiana M, Jawaid W, et al. The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1. EMBO J. 2019;38: pubmed publisher
Lee S, Abel E, Long F. Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018;9:4831 pubmed publisher
Fielding J, Hodson E, Cheng X, Ferguson D, Eckardt L, Adam J, et al. PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies. J Physiol. 2018;: pubmed publisher
Zelic M, Roderick J, O Donnell J, Lehman J, Lim S, Janardhan H, et al. RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome. J Clin Invest. 2018;128:2064-2075 pubmed publisher
Gao B, Lin X, Jing H, Fan J, Ji C, Jie Q, et al. Local delivery of tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal cells and creates an anti-inflammatory and angiogenic environment in aging mice. Aging Cell. 2018;17:e12741 pubmed publisher
Rhee S, Chung J, King D, D Amato G, Paik D, Duan A, et al. Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nat Commun. 2018;9:368 pubmed publisher
Li L, Zviti R, Ha C, Wang Z, Hill J, Lin F. Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction. J Biol Chem. 2017;292:13774-13783 pubmed publisher
Robinson S, Boult J, Vasudev N, Reynolds A. Monitoring the Vascular Response and Resistance to Sunitinib in Renal Cell Carcinoma In Vivo with Susceptibility Contrast MRI. Cancer Res. 2017;77:4127-4134 pubmed publisher
Park J, Kim M, Sun K, An Y, Gu X, Scherer P. VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4-Independent Metabolic Improvements. Diabetes. 2017;66:1479-1490 pubmed publisher
Langen U, Pitulescu M, Kim J, Enriquez Gasca R, Sivaraj K, Kusumbe A, et al. Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017;19:189-201 pubmed publisher
Ulvmar M, Martínez Corral I, Stanczuk L, Makinen T. Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins. Genesis. 2016;54:350-8 pubmed publisher
Baker M, Reynolds L, Robinson S, Lees D, Parsons M, Elia G, et al. Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth. PLoS ONE. 2013;8:e62516 pubmed publisher
Gil Henn H, Patsialou A, Wang Y, Warren M, Condeelis J, Koleske A. Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo. Oncogene. 2013;32:2622-30 pubmed publisher
Boimel P, Smirnova T, Zhou Z, Wyckoff J, Park H, Coniglio S, et al. Contribution of CXCL12 secretion to invasion of breast cancer cells. Breast Cancer Res. 2012;14:R23 pubmed
Rymo S, Gerhardt H, Wolfhagen Sand F, Lang R, Uv A, Betsholtz C. A two-way communication between microglial cells and angiogenic sprouts regulates angiogenesis in aortic ring cultures. PLoS ONE. 2011;6:e15846 pubmed publisher
product information
Product Name :
Endomucin (V.7C7) Antibody
Size :
200 µg/ml
Catalog Number :
sc-65495
Type :
Monoclonal
Host :
rat monoclonal
Antigen :
Endomucin
reactive species  :
mouse
Application :
WB, IP, IF, IHC(P), FCM
Epitope :
FL (m)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA