product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Ras GAP (B4F8) Antibody
catalog :
sc-63
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B4F8
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, other
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2a, s1e
Nataraj N, Noronha A, Lee J, Ghosh S, Mohan Raju H, Sekar A, et al. Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors. Cell Rep. 2022;38:110418 pubmed publisher
  • western blot; human; 1:250; fig 5
Roth Flach R, Guo C, Danai L, Yawe J, Gujja S, Edwards Y, et al. Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function. Mol Cell Biol. 2016;36:1740-9 pubmed publisher
  • western blot; human; 1:1000; fig 3
Jung Y, Decker A, Wang J, Lee E, Kana L, Yumoto K, et al. Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow. Oncotarget. 2016;7:25698-711 pubmed publisher
  • western blot; human; 1:100; fig 3
Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res. 2016;44:4745-62 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human; fig 7
  • western blot; mouse; fig 10
Edmonds M, Boyd K, Moyo T, Mitra R, Duszynski R, Arrate M, et al. MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer. J Clin Invest. 2016;126:349-64 pubmed publisher
  • western blot; human; 1:400; fig 8
Domínguez D, Feijoo P, Bernal A, Ercilla A, Agell N, Genescà A, et al. Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16INK4a deficiency and telomere-dependent genotoxic stress. Oncotarget. 2015;6:28238-56 pubmed publisher
Berger A, Chen M, Morotti A, Janas J, Niki M, Bronson R, et al. DOK2 inhibits EGFR-mutated lung adenocarcinoma. PLoS ONE. 2013;8:e79526 pubmed publisher
Llopis A, Salvador N, Ercilla A, Guaita Esteruelas S, Barrantes I, Gupta J, et al. The stress-activated protein kinases p38?/? and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest. Cell Cycle. 2012;11:3627-37 pubmed publisher
Mihrshahi R, Brown M. Downstream of tyrosine kinase 1 and 2 play opposing roles in CD200 receptor signaling. J Immunol. 2010;185:7216-22 pubmed publisher
Alvarez Moya B, López Alcalá C, Drosten M, Bachs O, Agell N. K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function. Oncogene. 2010;29:5911-22 pubmed publisher
Anand S, Majeti B, Acevedo L, Murphy E, Mukthavaram R, Scheppke L, et al. MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med. 2010;16:909-14 pubmed publisher
Mihrshahi R, Barclay A, Brown M. Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells. J Immunol. 2009;183:4879-86 pubmed publisher
Tsubouchi A, Sakakura J, Yagi R, Mazaki Y, Schaefer E, Yano H, et al. Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration. J Cell Biol. 2002;159:673-83 pubmed
Grimm J, Sachs M, Britsch S, Di Cesare S, Schwarz Romond T, Alitalo K, et al. Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation. J Cell Biol. 2001;154:345-54 pubmed
product information
Catalog Number :
sc-63
Product Name :
Ras GAP (B4F8) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
B4F8
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Ras GAP
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, FCM, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA