product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
MEK-1 (H-8) Antibody
catalog :
sc-6250
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-8
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; rat; fig 5
Li P, Sheu M, Ma W, Pan C, Sheu J, Wu C. Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells. Mar Drugs. 2015;13:3046-60 pubmed publisher
Yang Y, Wang S, Hung H, Chang C, Wu I, Huang Y, et al. Isolation and characterization of human gastric cell lines with stem cell phenotypes. J Gastroenterol Hepatol. 2007;22:1460-8 pubmed
Burgermeister E, Chuderland D, Hanoch T, Meyer M, Liscovitch M, Seger R. Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol Cell Biol. 2007;27:803-17 pubmed
Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwächter H, Zimmermann W, et al. The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain. Mol Cell Biol. 2011;31:3497-510 pubmed publisher
Robinson J, Pitcher J. G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade. Cell Signal. 2013;25:2831-9 pubmed publisher
Yang X, Li H, Deng A, Liu X. Plk1 phosphorylation of Topors is involved in its degradation. Mol Biol Rep. 2010;37:3023-8 pubmed publisher
Sugiura K, Naito K, Endo T, Tojo H. Study of germinal vesicle requirement for the normal kinetics of maturation/M-phase-promoting factor activity during porcine oocyte maturation. Biol Reprod. 2006;74:593-600 pubmed
Yang X, Li H, Liu X, Deng A, Liu X. Cdc2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication. J Biol Chem. 2009;284:28775-82 pubmed publisher
Majumdar A, Ghosh A, Datta S, Prudner B, Datta B. p67/MetAP2 suppresses K-RasV12-mediated transformation of NIH3T3 mouse fibroblasts in culture and in athymic mice. Biochemistry. 2010;49:10146-57 pubmed publisher
Chen G, Ghosh P, Longo D. Distinctive mechanism for sustained TGF-β signaling and growth inhibition: MEK1 activation-dependent stabilization of type II TGF-β receptors. Mol Cancer Res. 2011;9:78-89 pubmed publisher
Nelson D, Laman H. A Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteins. J Biol Chem. 2011;286:19804-15 pubmed publisher
product information
Product Name :
MEK-1 (H-8) Antibody
Gene Name :
MAP2K1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-6250
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
MEK-1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA