Published Application/Species/Sample/Dilution | Reference |
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- immunohistochemistry knockout validation; human; 1:200; fig 5a
| Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis N, et al. Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biol. 2018;19:37 pubmed publisher
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- western blot knockout validation; mouse; loading ...; fig 3d
| Choiniere J, Wu J, Wang L. Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins. Mol Pharmacol. 2017;91:189-196 pubmed publisher
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- western blot knockout validation; mouse; loading ...; fig 3h
| Hauck L, Grothe D, Billia F. p21(CIP1/WAF1)-dependent inhibition of cardiac hypertrophy in response to Angiotensin II involves Akt/Myc and pRb signaling. Peptides. 2016;83:38-48 pubmed publisher
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- western blot knockout validation; mouse; 1:1000
| Ahronian L, Driscoll D, Klimstra D, Lewis B. The p53R172H mutant does not enhance hepatocellular carcinoma development and progression. PLoS ONE. 2015;10:e0123816 pubmed publisher
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- western blot; mouse; 1:3000; loading ...; fig 4a, 7g
- western blot; human; 1:3000; loading ...; fig 4d, 8k
| Xia R, Liu T, Li W, Xu X. RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA. Clin Transl Med. 2021;11:e383 pubmed publisher
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- immunohistochemistry; human; fig s3i
| Prekovic S, Schuurman K, Mayayo Peralta I, Manjón A, Buijs M, Yavuz S, et al. Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer. Nat Commun. 2021;12:4360 pubmed publisher
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- western blot; rat; 1:200; loading ...; fig 5f
| Zhang Y, Hu M, Yang F, Zhang Y, Ma S, Zhang D, et al. Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin resistance. J Mol Med (Berl). 2021;99:1427-1446 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 1b, 1e, 1h
| Sanchez Rivera F, Ryan J, Soto Feliciano Y, Clare Beytagh M, Xuan L, Feldser D, et al. Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
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- western blot; human; 1:400; fig 6f
| Plácido L, Romero Y, Maldonado M, Toscano Marquez F, Ramirez R, Calyeca J, et al. Loss of MT1-MMP in Alveolar Epithelial Cells Exacerbates Pulmonary Fibrosis. Int J Mol Sci. 2021;22: pubmed publisher
|
- mass cytometry; mouse; loading ...; fig s3
| Lagnado A, Leslie J, Ruchaud Sparagano M, Victorelli S, Hirsova P, Ogrodnik M, et al. Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner. EMBO J. 2021;40:e106048 pubmed publisher
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- western blot; mouse; 1:200; loading ...; fig 2h
| Dewhurst M, Ow J, Zafer G, Van Hul N, Wollmann H, Bisteau X, et al. Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020;16:e1009084 pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig 3e
| Zhang J, Huang J, Zhang Y, Zhang X, Zhao L, Li C, et al. Microtubule associated protein 9 inhibits liver tumorigenesis by suppressing ERCC3. EBioMedicine. 2020;53:102701 pubmed publisher
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- western blot; rat; 1:200; loading ...; fig 5b
| Lin Y, Huang X, Chang K, Liao K, Tsai N. Encapsulated n-Butylidenephthalide Efficiently Crosses the Blood-Brain Barrier and Suppresses Growth of Glioblastoma. Int J Nanomedicine. 2020;15:749-760 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3d
- western blot; mouse; 1:1000; loading ...; fig 3a, 3b, 3c, s6c
| Cassidy L, Young A, Young C, Soilleux E, Fielder E, Weigand B, et al. Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk. Nat Commun. 2020;11:307 pubmed publisher
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- immunohistochemistry - paraffin section; human; loading ...; fig 6d
| Aldaz P, Otaegi Ugartemendia M, Sáenz Antoñanzas A, Garcia Puga M, Moreno Valladares M, Flores J, et al. SOX9 promotes tumor progression through the axis BMI1-p21CIP. Sci Rep. 2020;10:357 pubmed publisher
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- western blot; mouse; loading ...; fig s3e
| Ko H, Hwang I, Jin E, Yun T, Ryu D, Kang J, et al. Roles of ErbB3-binding protein 1 (EBP1) in embryonic development and gene-silencing control. Proc Natl Acad Sci U S A. 2019;116:24852-24860 pubmed publisher
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- western blot; human; loading ...; fig 2d
| Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, et al. Inducing and exploiting vulnerabilities for the treatment of liver cancer. Nature. 2019;: pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig s2e
| Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed publisher
|
- western blot; mouse; 1:250; loading ...; fig 2h
| Diaz Osterman C, Ozmadenci D, Kleinschmidt E, Taylor K, Barrie A, Jiang S, et al. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. elife. 2019;8: pubmed publisher
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- western blot; mouse; 666 ng/ml; loading ...; fig 4c
| Choi J, Zhong X, McAlpine W, Liao T, Zhang D, Fang B, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science. 2019;364: pubmed publisher
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- immunocytochemistry; human; 1:100; loading ...; fig e5c, e5e
| Chan E, Shibue T, McFarland J, Gaeta B, Ghandi M, Dumont N, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568:551-556 pubmed publisher
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- western blot; human; loading ...; fig s6c
| Ao Y, Zhang J, Liu Z, Qian M, Li Y, Wu Z, et al. Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model. Sci Adv. 2019;5:eaav5078 pubmed publisher
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- western blot; human; 1:100; loading ...; fig s8a
| Pillay N, Tighe A, Nelson L, Littler S, Coulson Gilmer C, Bah N, et al. DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors. Cancer Cell. 2019;35:519-533.e8 pubmed publisher
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- western blot; human; loading ...; fig 7c
| Zhao Y, Ding L, Wang D, Ye Z, He Y, Ma L, et al. EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis. EMBO J. 2019;38: pubmed publisher
|
- western blot; mouse; loading ...; fig s7b
| Gronke K, Hernandez P, Zimmermann J, Klose C, Kofoed Branzk M, Guendel F, et al. Interleukin-22 protects intestinal stem cells against genotoxic stress. Nature. 2019;566:249-253 pubmed publisher
|
- western blot; human; loading ...; fig 4d
| Kim S, Jin H, Seo H, Lee H, Lee Y. Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation. Cell Death Differ. 2019;26:812-825 pubmed publisher
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- western blot; mouse; 1:200; loading ...; fig 4o
| Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed publisher
|
- immunoprecipitation; mouse; loading ...; fig 5b
| Hsu J, Hubbell Engler B, Adelmant G, Huang J, Joyce C, Vazquez F, et al. PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer. Cancer Res. 2017;77:4613-4625 pubmed publisher
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- western blot; human; loading ...; fig 5c
| He D, Ren B, Liu S, Tan L, Cieply K, Tseng G, et al. Oncogenic activity of amplified miniature chromosome maintenance 8 in human malignancies. Oncogene. 2017;36:3629-3639 pubmed publisher
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- western blot; human; loading ...; fig 3d
| Teveroni E, Pellegrino M, Sacconi S, Calandra P, Cascino I, Farioli Vecchioli S, et al. Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity. J Clin Invest. 2017;127:1531-1545 pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig 7a
| Li G, Ji T, Chen J, Fu Y, Hou L, Feng Y, et al. CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver. Cell Rep. 2017;18:1499-1511 pubmed publisher
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- western blot; mouse; loading ...; fig 4b
| Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5d
| Vendetti F, Leibowitz B, Barnes J, Schamus S, Kiesel B, Abberbock S, et al. Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation. Sci Rep. 2017;7:41892 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 5a
| Yu G, Dou Z, Jia Z. 5?bromo?3?(3?hydroxyprop?1?ynyl)?2H?pyran?2?one induces apoptosis in T24 human bladder cancer cells through mitochondria-dependent signaling pathways. Mol Med Rep. 2017;15:153-159 pubmed publisher
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- western blot; rat; 1:250; loading ...; fig 3a
| Suman S, Kumar S, N GOUEMO P, Datta K. Increased DNA double-strand break was associated with downregulation of repair and upregulation of apoptotic factors in rat hippocampus after alcohol exposure. Alcohol. 2016;54:45-50 pubmed publisher
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- western blot; human; 1:200; loading ...; fig 6c
| Mihailidou C, Panagiotou C, Kiaris H, Kassi E, Moutsatsou P. Crosstalk between C/EBP homologous protein (CHOP) and glucocorticoid receptor in lung cancer. Mol Cell Endocrinol. 2016;436:211-23 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 4a
| Lu H, Yang X, Tian X, Tang S, Li L, Zhao S, et al. The in vitro and vivo anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) and MG132 on the aggressive phenotypes of gastric cancer cells. Oncotarget. 2016;7:56508-56525 pubmed publisher
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- western blot; human; loading ...; fig 3b
| Lefort K, Ostano P, Mello Grand M, Calpini V, Scatolini M, Farsetti A, et al. Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer. Oncotarget. 2016;7:48011-48026 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1f
- western blot; human; loading ...; fig 1b
| Janjanam J, Rao G. Novel role of cortactin in G protein-coupled receptor agonist-induced nuclear export and degradation of p21Cip1. Sci Rep. 2016;6:28687 pubmed publisher
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- western blot; human; fig 1c
| Hendrayani S, Al Harbi B, Al Ansari M, Silva G, Aboussekhra A. The inflammatory/cancer-related IL-6/STAT3/NF-?B positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts. Oncotarget. 2016;7:41974-41985 pubmed publisher
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- western blot; human; loading ...; fig s4
| Avila A, Illing A, Becker F, Maerz L, Morita Y, Philipp M, et al. Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation. Nucleic Acids Res. 2016;44:6252-61 pubmed publisher
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- western blot; human; fig s1
| Zhuang L, Yang Y, Ma X, Han B, Wang Z, Zhao Q, et al. MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST. Cell Death Dis. 2016;7:e2203 pubmed publisher
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- immunohistochemistry - frozen section; mouse; fig 3
| Seidel P, Remus M, Delacher M, Grigaravicius P, Reuss D, Frappart L, et al. Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis. Oncotarget. 2016;7:23006-18 pubmed publisher
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- western blot; human; fig 5
| Cao C, Wang Z, Huang L, Bai L, Wang Y, Liang Y, et al. Down-regulation of tumor endothelial marker 8 suppresses cell proliferation mediated by ERK1/2 activity. Sci Rep. 2016;6:23419 pubmed publisher
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- western blot; mouse; 1:1000; fig 3a
| Lee H, Dai F, Zhuang L, Xiao Z, Kim J, Zhang Y, et al. BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21. Oncotarget. 2016;7:19134-46 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 8
| Weeks R, Ludgate J, LeMée G, Morison I. TESTIN Induces Rapid Death and Suppresses Proliferation in Childhood B Acute Lymphoblastic Leukaemia Cells. PLoS ONE. 2016;11:e0151341 pubmed publisher
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- western blot; human; loading ...; fig 5c
| Xie X, Lozano G, Siddik Z. Heterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53. Oncogene. 2016;35:4798-806 pubmed publisher
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- western blot; mouse; fig s2
| Le Trilling V, Megger D, Katschinski B, Landsberg C, Rückborn M, Tao S, et al. Broad and potent antiviral activity of the NAE inhibitor MLN4924. Sci Rep. 2016;6:19977 pubmed publisher
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- western blot; human; 1:500; loading ...; fig st3
| Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun. 2016;7:10399 pubmed publisher
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- western blot; human; 1:200; fig 3
| Qiu L, Wu J, Pan C, Tan X, Lin J, Liu R, et al. Downregulation of CDC27 inhibits the proliferation of colorectal cancer cells via the accumulation of p21Cip1/Waf1. Cell Death Dis. 2016;7:e2074 pubmed publisher
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- western blot; human; fig 5
| Cousin F, Jouan Lanhouet S, Théret N, Brenner C, Jouan E, Le Moigne Muller G, et al. The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer. Oncotarget. 2016;7:7161-78 pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig 7a
| Guo Z, Kong Q, Liu C, Zhang S, Zou L, Yan F, et al. DCAF1 controls T-cell function via p53-dependent and -independent mechanisms. Nat Commun. 2016;7:10307 pubmed publisher
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- western blot; mouse; 1:50; fig 1d
| Kondo H, Kim H, Wang L, Okada M, Paul C, Millard R, et al. Blockade of senescence-associated microRNA-195 in aged skeletal muscle cells facilitates reprogramming to produce induced pluripotent stem cells. Aging Cell. 2016;15:56-66 pubmed publisher
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| MartÃn Pardillos A, Sorribas V. Effects of donor age and proliferative aging on the phenotype stability of rat aortic smooth muscle cells. Physiol Rep. 2015;3: pubmed publisher
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- western blot; human; 1:500; fig 3
| Dewaele M, Tabaglio T, Willekens K, Bezzi M, Teo S, Low D, et al. Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth. J Clin Invest. 2016;126:68-84 pubmed publisher
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- western blot; mouse; fig 8
| Kraut B, Maier H, Kókai E, Fiedler K, Boettger T, Illing A, et al. Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality. PLoS ONE. 2015;10:e0141591 pubmed publisher
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- western blot; human; fig 6
| Lee N, Kwon J, Kim Y, Kim S, Park S, Xu W, et al. Vaccinia-related kinase 1 promotes hepatocellular carcinoma by controlling the levels of cell cycle regulators associated with G1/S transition. Oncotarget. 2015;6:30130-48 pubmed publisher
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- western blot; human; fig 2
| Zhang X, Wang X, Wu T, Li B, Liu T, Wang R, et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Sci Rep. 2015;5:12579 pubmed publisher
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| Succoio M, Comegna M, D Ambrosio C, Scaloni A, Cimino F, Faraonio R. Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence. J Proteomics. 2015;128:18-29 pubmed publisher
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| Galoian K, Qureshi A, D Ippolito G, Schiller P, Molinari M, Johnstone A, et al. Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1. Int J Oncol. 2015;47:465-72 pubmed publisher
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- western blot; mouse; 1:500; fig 1
| Rueda Rincon N, Bloch K, Derua R, Vyas R, Harms A, Hankemeier T, et al. p53 attenuates AKT signaling by modulating membrane phospholipid composition. Oncotarget. 2015;6:21240-54 pubmed
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- western blot; human; loading ...; fig 4a
| Kotipatruni R, Ren X, Thotala D, Jaboin J. NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells. Oncotarget. 2015;6:17594-604 pubmed
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- western blot; human; fig 1
| Chen P, Wu T, Cheng Y, Chen C, Lee H. NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation. Oncotarget. 2015;6:14274-89 pubmed
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- immunoprecipitation; human
- western blot; human
| Scialpi F, Mellis D, Ditzel M. EDD, a ubiquitin-protein ligase of the N-end rule pathway, associates with spindle assembly checkpoint components and regulates the mitotic response to nocodazole. J Biol Chem. 2015;290:12585-94 pubmed publisher
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- immunocytochemistry; human; fig 1
| Meena J, Cerutti A, Beichler C, Morita Y, Bruhn C, Kumar M, et al. Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion. EMBO J. 2015;34:1371-84 pubmed publisher
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- western blot; mouse; fig 6
| Kirschner K, Samarajiwa S, Cairns J, Menon S, Perez Mancera P, Tomimatsu K, et al. Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PLoS Genet. 2015;11:e1005053 pubmed publisher
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| Albers J, Danzer C, Rechsteiner M, Lehmann H, Brandt L, Hejhal T, et al. A versatile modular vector system for rapid combinatorial mammalian genetics. J Clin Invest. 2015;125:1603-19 pubmed publisher
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| Chen Y, Terajima M, Yang Y, Sun L, Ahn Y, Panková D, et al. Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. J Clin Invest. 2015;125:1147-62 pubmed publisher
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- western blot; human; fig s2
| Rao R, Dhele N, Cheemadan S, Ketkar A, Jayandharan G, Palakodeti D, et al. Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming. Sci Rep. 2015;5:8229 pubmed publisher
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- western blot; human; fig 4
| Iglesias Gato D, Chuan Y, Jiang N, Svensson C, Bao J, Paul I, et al. OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo. Mol Cancer. 2015;14:8 pubmed publisher
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- western blot; mouse; 1:300; fig 5
| Suzuki D, Sahu R, Leu N, Senoo M. The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells. Development. 2015;142:282-90 pubmed publisher
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- western blot; human; 1:500
| Wei Z, Guo H, Liu Z, Zhang X, Liu Q, Qian Y, et al. CUL4B impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop. Free Radic Biol Med. 2015;79:1-13 pubmed publisher
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- western blot; human; 1:1000
| Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed publisher
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- western blot; human; loading ...; fig 3c
| Peterson E, Menon V, Gatti L, Kipping R, Dewasinghe D, Perego P, et al. Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction. Mol Pharm. 2015;12:287-97 pubmed publisher
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- western blot; mouse; 1:1000
| Bongers K, Fox D, Kunkel S, Stebounova L, Murry D, Pufall M, et al. Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy. Am J Physiol Endocrinol Metab. 2015;308:E144-58 pubmed publisher
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| Chen J, Shin J, Zhao R, Phan L, Wang H, Xue Y, et al. CSN6 drives carcinogenesis by positively regulating Myc stability. Nat Commun. 2014;5:5384 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:50
- western blot; human; 1:500
| Liu X, Yang W, Zheng P. Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomas. Oncotarget. 2014;5:10870-85 pubmed
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- immunocytochemistry; mouse
- western blot; mouse
| Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
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- immunohistochemistry - paraffin section; mouse
| Wang T, Guo S, Liu Z, Wu L, Li M, Yang J, et al. CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling. Oncotarget. 2014;5:10293-306 pubmed
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- western blot; human; fig 1
| Patwardhan G, Hosain S, Liu D, Khiste S, Zhao Y, Bielawski J, et al. Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells. Biochim Biophys Acta. 2014;1841:1571-80 pubmed publisher
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- western blot; human; 0.2 ug/ml
| Jacob A, Singh R, Comiskey D, Rouhier M, Mohammad F, Bebee T, et al. Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways. PLoS ONE. 2014;9:e104444 pubmed publisher
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- western blot; human
- western blot; mouse
| Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed publisher
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- western blot; human; fig 6d
| Hamilton G, Abraham A, Morton J, Sampson O, Pefani D, Khoronenkova S, et al. AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Oncotarget. 2014;5:6142-67 pubmed
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| Tabor V, Bocci M, Alikhani N, Kuiper R, Larsson L. MYC synergizes with activated BRAFV600E in mouse lung tumor development by suppressing senescence. Cancer Res. 2014;74:4222-9 pubmed publisher
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- western blot; human; fig 6
| Otani K, Dong Y, Li X, Lu J, Zhang N, Xu L, et al. Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer. J Pathol. 2014;234:302-15 pubmed publisher
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- western blot; mouse; 1:1000
| Kaneko Y, Ota A, Nakashima A, Nagasaki H, Kodani Y, Mori K, et al. Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G? phase and protects them from UV light-induced apoptosis. J Neural Transm (Vienna). 2015;122:187-99 pubmed publisher
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- western blot; mouse; fig 1
| Ying Y, Kim J, Westphal S, Long K, Padanilam B. Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury. J Am Soc Nephrol. 2014;25:2707-16 pubmed publisher
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| Machado Neto J, Lazarini M, Favaro P, Franchi G, Nowill A, Saad S, et al. ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells. Exp Cell Res. 2014;324:137-45 pubmed publisher
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- western blot; human; 1:100; fig 3c
| Okada N, Lin C, Ribeiro M, Biton A, Lai G, He X, et al. A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression. Genes Dev. 2014;28:438-50 pubmed publisher
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- immunohistochemistry - paraffin section; mouse
| Aoshiba K, Tsuji T, Itoh M, Semba S, Yamaguchi K, Nakamura H, et al. A murine model of airway fibrosis induced by repeated naphthalene exposure. Exp Toxicol Pathol. 2014;66:169-77 pubmed publisher
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- western blot; mouse; fig 5
| Jackson D, Li H, Mitchell K, Joshi A, Elferink C. Ah receptor-mediated suppression of liver regeneration through NC-XRE-driven p21Cip1 expression. Mol Pharmacol. 2014;85:533-41 pubmed publisher
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- western blot; human; fig 6
| Bots M, Verbrugge I, Martin B, Salmon J, Ghisi M, Baker A, et al. Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood. 2014;123:1341-52 pubmed publisher
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- immunohistochemistry - paraffin section; mouse
| Aoshiba K, Tsuji T, Kameyama S, Itoh M, Semba S, Yamaguchi K, et al. Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury. Exp Toxicol Pathol. 2013;65:1053-62 pubmed publisher
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| Jelinek M, Balusikova K, Kopperová D, Němcová Fürstová V, Srámek J, Fidlerova J, et al. Caspase-2 is involved in cell death induction by taxanes in breast cancer cells. Cancer Cell Int. 2013;13:42 pubmed publisher
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| Kuchenreuther M, Weber J. The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation. Oncogene. 2014;33:300-7 pubmed publisher
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- western blot; mouse; 1:1000
| Kohn E, Yang Y, Du Z, Nagano Y, Van Schyndle C, Herrmann M, et al. Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression. Mol Cancer Res. 2012;10:1389-99 pubmed publisher
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- western blot; mouse; fig 4
| Diril M, Ratnacaram C, Padmakumar V, Du T, Wasser M, Coppola V, et al. Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration. Proc Natl Acad Sci U S A. 2012;109:3826-31 pubmed publisher
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- western blot; mouse; fig 1
| Pinho A, Rooman I, Real F. p53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells. Cell Cycle. 2011;10:1312-21 pubmed
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| Siatecka M, Lohmann F, Bao S, Bieker J. EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation. Mol Cell Biol. 2010;30:2811-22 pubmed publisher
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| Lucas D, Escudero B, Ligos J, Segovia J, Estrada J, Terrados G, et al. Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair. PLoS Genet. 2009;5:e1000389 pubmed publisher
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- immunohistochemistry; mouse
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