This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Jagged1 (C-20)
catalog :
sc-6011
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; fig 1a
Rahman M, Hazan A, Selway J, Herath D, Harwood C, Pirzado M, et al. A Novel Mechanism for Activation of GLI1 by Nuclear SMO That Escapes Anti-SMO Inhibitors. Cancer Res. 2018;78:2577-2588 pubmed publisher
  • western blot; human; loading ...; fig 7b
Wang Z, Kim M, Martinez Ferrando I, Koleske A, Pandey A, Cole P. Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase. Biochemistry. 2018;57:1390-1398 pubmed publisher
  • western blot; human; fig 1a
Zunke F, Moise A, Belur N, Gelyana E, Stojkovska I, Dzaferbegovic H, et al. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron. 2018;97:92-107.e10 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 4o
Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
  • immunoprecipitation; human; fig s2a
  • western blot; human; fig s2a
Antfolk D, Sjöqvist M, Cheng F, Isoniemi K, Duran C, Rivero Muller A, et al. Selective regulation of Notch ligands during angiogenesis is mediated by vimentin. Proc Natl Acad Sci U S A. 2017;114:E4574-E4581 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5c
Zhu X, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, et al. A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017;292:9409-9419 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 2c
  • western blot; mouse; 1:500; loading ...; fig 2d
Su Q, Zhang B, Zhang L, Dang T, Rowley D, Ittmann M, et al. Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer. Oncogene. 2017;36:618-627 pubmed publisher
  • immunocytochemistry; human; 2 ug/ml; fig 1d
  • western blot; human; 1:2000; fig 1b
Gomi K, Staudt M, Salit J, Kaner R, Heldrich J, Rogalski A, et al. JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium. Stem Cell Rev. 2016;12:454-63 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 8
Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; mouse; loading ...; fig 8
Rothaug M, Stroobants S, Schweizer M, Peters J, Zunke F, Allerding M, et al. LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease. Acta Neuropathol Commun. 2015;3:6 pubmed publisher
  • western blot; mouse; fig 2
Yang Y, Ahn Y, Gibbons D, Zang Y, Lin W, Thilaganathan N, et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest. 2011;121:1373-85 pubmed publisher
Azimi M, Brown N. Jagged1 protein processing in the developing mammalian lens. Biol Open. 2019;8: pubmed publisher
Samarajeewa A, Lenz D, Xie L, Chiang H, Kirchner R, Mulvaney J, et al. Transcriptional response to Wnt activation regulates the regenerative capacity of the mammalian cochlea. Development. 2018;145: pubmed publisher
López Arribillaga E, Rodilla V, Colomer C, Vert A, Shelton A, Cheng J, et al. Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells. Nat Commun. 2018;9:2992 pubmed publisher
Azimi M, Le T, Brown N. Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens. Differentiation. 2018;102:40-52 pubmed publisher
Nonneman A, Criem N, Lewandowski S, Nuyts R, Thal D, Pfrieger F, et al. Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis. Neurobiol Dis. 2018;119:26-40 pubmed publisher
Huang Y, Hill J, Yatteau A, Wong L, Jiang T, Petrovic J, et al. Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation. J Neurosci. 2018;38:5429-5440 pubmed publisher
Cabrera R, Mao S, Surve C, Condeelis J, Segall J. A novel neuregulin - jagged1 paracrine loop in breast cancer transendothelial migration. Breast Cancer Res. 2018;20:24 pubmed publisher
Prasasya R, Mayo K. Notch Signaling Regulates Differentiation and Steroidogenesis in Female Mouse Ovarian Granulosa Cells. Endocrinology. 2018;159:184-198 pubmed publisher
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA