product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
β-catenin (12F7) Antibody
catalog :
sc-59737
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
12F7
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; loading ...; fig 3f
Brito V, Patrocinio M, Sousa M, Barreto A, Frasnelli S, Lara V, et al. Mast cells contribute to alveolar bone loss in Spontaneously Hypertensive Rats with periodontal disease regulating cytokines production. PLoS ONE. 2021;16:e0247372 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 2d
Scotti L, Di Pietro M, Pascuali N, Irusta G, I de Zúñiga -, Gomez Peña M, et al. Sphingosine-1-phosphate restores endothelial barrier integrity in ovarian hyperstimulation syndrome. Mol Hum Reprod. 2016;22:852-866 pubmed
  • immunohistochemistry - paraffin section; mouse; fig 5h
Ro S, Xue X, Ramakrishnan S, Cho C, Namkoong S, Jang I, et al. Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis. elife. 2016;5:e12204 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
Chang L, Lei X, Qin Y, Zeng G, Zhang X, Jin H, et al. Expression and prognostic value of SFRP1 and β-catenin in patients with glioblastoma. Oncol Lett. 2016;11:69-74 pubmed
  • immunohistochemistry - paraffin section; rat; 1:50; fig 4
  • western blot; rat; 1:50; fig 2
Liu S, Zhou P, Zhang Y. Abnormal expression of key genes and proteins in the canonical Wnt/β-catenin pathway of articular cartilage in a rat model of exercise-induced osteoarthritis. Mol Med Rep. 2016;13:1999-2006 pubmed publisher
  • western blot; human; 1:500; fig 3c
Ma S, Yang L, Niu T, Cheng C, Zhong L, Zheng M, et al. SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML. Sci Rep. 2015;5:15646 pubmed publisher
Kim Y, Kim D, Zhang H, Bae C, Seong D, Kim Y, et al. DIX domain containing 1 (DIXDC1) modulates VEGFR2 level in vasculatures to regulate embryonic and postnatal retina angiogenesis. BMC Biol. 2022;20:41 pubmed publisher
Howden J, Michael M, Hight Warburton W, Parsons M. α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions. BMC Biol. 2021;19:130 pubmed publisher
Lambers C, Boehm P, Karabacak Y, Samaha E, Benazzo A, Jaksch P, et al. Combined Activation of Guanylate Cyclase and Cyclic AMP in Lung Fibroblasts as a Novel Therapeutic Concept for Lung Fibrosis. Biomed Res Int. 2019;2019:1345402 pubmed publisher
Zhao Z, Luo J, Li H, Wang S, Li X. SOX2-mediated inhibition of miR-223 contributes to STIM1 activation in phenylephrine-induced hypertrophic cardiomyocytes. Mol Cell Biochem. 2018;443:47-56 pubmed publisher
Chen C, Xue Y, Zhang D, Xu W, Xu H, Yao H, et al. Short hairpin RNA silencing of TGF-?RII and FZD-7 synergistically suppresses proliferation and metastasis of hepatocellular carcinoma cells. Oncol Lett. 2016;11:2039-2046 pubmed
Li W, Zhang L, Li H, Zheng S, Zhao L. WISP-1 contributes to fractionated irradiation-induced radioresistance in esophageal carcinoma cell lines and mice. PLoS ONE. 2014;9:e94751 pubmed publisher
Rauchfuss F, Lambeck S, Claus R, Ullmann J, Schulz T, Weber M, et al. Sustained liver regeneration after portal vein embolization --a human molecular pilot study. Dig Liver Dis. 2012;44:681-8 pubmed publisher
Lee S, Tsai C, Tsai L, Chou M, Chou M, Chang Y. ?-catenin expression in areca quid chewing-associated oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells. J Formos Med Assoc. 2012;111:194-200 pubmed publisher
Zhang F, Yang Q, Meng F, Shi H, Li H, Liang Y, et al. Astrocyte elevated gene-1 interacts with ?-catenin and increases migration and invasion of colorectal carcinoma. Mol Carcinog. 2013;52:603-10 pubmed publisher
Song L, Liu R, Zeng Z, Alper S, Cui H, Lu Y, et al. Gastrin inhibits a novel, pathological colon cancer signaling pathway involving EGR1, AE2, and P-ERK. J Mol Med (Berl). 2012;90:707-18 pubmed publisher
Li J, Li J, Chen B. Oct4 was a novel target of Wnt signaling pathway. Mol Cell Biochem. 2012;362:233-40 pubmed publisher
Kong Y, Bai P, Nan K, Sun H, Chen N, Qi X. Pleiotrophin is a potential colorectal cancer prognostic factor that promotes VEGF expression and induces angiogenesis in colorectal cancer. Int J Colorectal Dis. 2012;27:287-98 pubmed publisher
Tong J, Li W, Vidal C, Yeo L, Fatkin D, Duque G. Lamin A/C deficiency is associated with fat infiltration of muscle and bone. Mech Ageing Dev. 2011;132:552-9 pubmed publisher
Li B, Jia Z, Wang T, Wang W, Zhang C, Chen P, et al. Interaction of Wnt/?-catenin and notch signaling in the early stage of cardiac differentiation of P19CL6 cells. J Cell Biochem. 2012;113:629-39 pubmed publisher
Xiong M, Zhang H, Jin L, Ai J, Huang Z, Zhu G. Association of controlled ovarian hyperstimulation treatment with down-regulation of key regulators involved in embryonic implantation in mice. J Huazhong Univ Sci Technolog Med Sci. 2011;31:535 pubmed publisher
Saydam O, Shen Y, Wurdinger T, Senol O, Boke E, James M, et al. Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway. Mol Cell Biol. 2009;29:5923-40 pubmed publisher
Song J, Stefanik D, Damek Poprawa M, Alawi F, Akintoye S. Differentiation and regenerative capacities of human odontoma-derived mesenchymal cells. Differentiation. 2009;77:29-37 pubmed publisher
product information
Catalog Number :
sc-59737
Product Name :
β-catenin (12F7) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
12F7
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
beta-catenin
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA