This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PrP (6D11) Antibody
catalog :
sc-58581
quantity :
50 µg/0.5 ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6D11
reactivity :
hamsters, African green monkey, human, mouse, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, other
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; bovine; loading ...; fig 1
  • western blot; African green monkey; loading ...; fig 1
  • western blot; human; loading ...; fig 1
Piccardo P, Cervenak J, Goldmann W, Stewart P, Pomeroy K, Gregori L, et al. Experimental Bovine Spongiform Encephalopathy in Squirrel Monkeys: The Same Complex Proteinopathy Appearing after Very Different Incubation Times. Pathogens. 2022;11: pubmed publisher
  • western blot; mouse; fig 1a
Silverman J, Christy D, Shyu C, Moon K, Fernando S, Gidden Z, et al. CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1. J Biol Chem. 2019;294:3744-3759 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
  • western blot; mouse; fig 3
Xiao K, Zhang B, Zhang X, Wang J, Chen C, Chen L, et al. Re-infection of the prion from the scrapie‑infected cell line SMB-S15 in three strains of mice, CD1, C57BL/6 and Balb/c. Int J Mol Med. 2016;37:716-26 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Reis R, Hennessy E, Murray C, Griffin Ã, Cunningham C. At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei. Neuropathol Appl Neurobiol. 2015;41:780-97 pubmed publisher
  • other; mouse; 1:50; loading ...; fig 2a
Woo J, Zhao X, Khan H, Penn C, Wang X, Joly Amado A, et al. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ. 2015;22:921-34 pubmed publisher
  • immunocytochemistry; hamsters; 1:100
  • western blot; hamsters
Wang J, Zhang J, Shi Q, Zhang B, Chen C, Chen L, et al. Scrapie infection in experimental rodents and SMB-S15 cells decreased the brain endogenous levels and activities of Sirt1. J Mol Neurosci. 2015;55:1022-30 pubmed publisher
Nazmi A, Field R, Griffin E, Haugh O, Hennessy E, Cox D, et al. Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression. Glia. 2019;67:1254-1276 pubmed publisher
Botto L, Cunati D, Coco S, Sesana S, Bulbarelli A, Biasini E, et al. Role of lipid rafts and GM1 in the segregation and processing of prion protein. PLoS ONE. 2014;9:e98344 pubmed publisher
Wei X, Roettger Y, Tan B, He Y, Dodel R, Hampel H, et al. Human anti-prion antibodies block prion peptide fibril formation and neurotoxicity. J Biol Chem. 2012;287:12858-66 pubmed publisher
product information
Product Name :
PrP (6D11) Antibody
Gene Name :
PRNP
Size :
50 µg/0.5 ml
Catalog Number :
sc-58581
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
PrP
reactive species  :
m, h, bovine
Application :
WB, IF, IHC(P)
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA