product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Chk1 (DCS-310) Antibody
catalog :
sc-56291
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DCS-310
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:100; fig 6
Parameswaran B, Chiang H, Lu Y, Coates J, Deng C, Baer R, et al. Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection. Cell Cycle. 2015;14:437-48 pubmed publisher
  • western blot; human; 1:1000
Schmidt L, Wiedner M, Velimezi G, Prochazkova J, Owusu M, Bauer S, et al. ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress. DNA Repair (Amst). 2014;24:122-130 pubmed publisher
  • western blot; human
Belanger F, Rajotte V, Drobetsky E. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. PLoS ONE. 2014;9:e85294 pubmed publisher
Mayca Pozo F, Tang J, Bonk K, Keri R, Yao X, Zhang Y. Regulatory cross-talk determines the cellular levels of 53BP1 protein, a critical factor in DNA repair. J Biol Chem. 2017;292:5992-6003 pubmed publisher
Jørgensen S, Eskildsen M, Fugger K, Hansen L, Larsen M, Kousholt A, et al. SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation. J Cell Biol. 2011;192:43-54 pubmed publisher
Shimada M, Haruta M, Niida H, Sawamoto K, Nakanishi M. Protein phosphatase 1? is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage. EMBO Rep. 2010;11:883-9 pubmed publisher
product information
Catalog Number :
sc-56291
Product Name :
Chk1 (DCS-310) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
DCS-310
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Chk1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA