This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PML (H-238)
catalog :
sc-5621
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; loading ...; fig 3c
Han M, Napier C, Frölich S, Teber E, Wong T, Noble J, et al. Synthetic lethality of cytolytic HSV-1 in cancer cells with ATRX and PML deficiency. J Cell Sci. 2019;132: pubmed publisher
  • western blot; human; loading ...; fig 5c
Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 4b
Forlani G, Tosi G, Turrini F, Poli G, Vicenzi E, Accolla R. Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1. Front Immunol. 2017;8:564 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b
Jo S, Lee Y, Kim S, Lee H, Chung H. PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells. Biochim Biophys Acta. 2016;1863:1499-509 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 1
Buczek M, Miles A, Green W, Johnson C, Boocock D, Pockley A, et al. Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer. Oncogene. 2016;35:3465-75 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 1d
Clynes D, Jelinska C, Xella B, Ayyub H, Scott C, Mitson M, et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun. 2015;6:7538 pubmed publisher
Takasugi T, Gu P, Liang F, Staco I, Chang S. Pot1b -/- tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation. Nucleic Acids Res. 2023;51:9227-9247 pubmed publisher
Ravasio R, Ceccacci E, Nicosia L, Hosseini A, Rossi P, Barozzi I, et al. Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation. Sci Adv. 2020;6:eaax2746 pubmed publisher
Li C, McManus F, Plutoni C, Pascariu C, Nelson T, Alberici Delsin L, et al. Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility. Nat Commun. 2020;11:834 pubmed publisher
Datta N, Islam S, Chatterjee U, Chatterjee S, Panda C, Ghosh M. Promyelocytic Leukemia (PML) gene regulation: implication towards curbing oncogenesis. Cell Death Dis. 2019;10:656 pubmed publisher
Manfredi L, Ang J, Peker N, Dagda R, McFarlane C. G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells. Am J Physiol Cell Physiol. 2019;317:C674-C686 pubmed publisher
Hou W, Cruz Cosme R, Wen F, Ahn J, Reeves I, Luo M, et al. Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0. J Virol. 2018;92: pubmed publisher
Cohen C, Corpet A, Roubille S, Maroui M, Poccardi N, Rousseau A, et al. Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone Axis. PLoS Pathog. 2018;14:e1007313 pubmed publisher
Rai T, Glass M, Cole J, Rather M, Marsden M, Neilson M, et al. Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity. Nucleic Acids Res. 2017;45:11673-11683 pubmed publisher
Ahmed A, Wan X, Mitxitorena I, Lindsay A, Paolo Pandolfi P, McCaffrey M, et al. Regulation of NF-κB by PML and PML-RARα. Sci Rep. 2017;7:44539 pubmed publisher
Coluzzi E, Buonsante R, Leone S, Asmar A, Miller K, Cimini D, et al. Transient ALT activation protects human primary cells from chromosome instability induced by low chronic oxidative stress. Sci Rep. 2017;7:43309 pubmed publisher
Noguera N, Piredda M, Taulli R, Catalano G, Angelini G, Gaur G, et al. PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity. Oncotarget. 2016;7:66386-66397 pubmed publisher
CONSTANZO J, Deng M, Rindhe S, Tang K, Zhang C, Scaglioni P. Pias1 is essential for erythroid and vascular development in the mouse embryo. Dev Biol. 2016;415:98-110 pubmed publisher
Grindheim A, Hollås H, Raddum A, Saraste J, Vedeler A. Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2. J Cell Sci. 2016;129:314-28 pubmed publisher
Brown J, Leach J, Reittie J, Atzberger A, Lee Prudhoe J, Wood W, et al. Coregulated human globin genes are frequently in spatial proximity when active. J Cell Biol. 2006;172:177-87 pubmed
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA