product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
cleaved PARP-1 (194C1439) Antibody
catalog :
sc-56196
quantity :
50 µg/0.5 ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
194C1439
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:2000; loading ...; fig 5f
Ma N, Li G, Fu X. Protective role of activating transcription factor 3 against neuronal damage in rats with cerebral ischemia. Brain Behav. 2022;12:e2522 pubmed publisher
  • western blot; human; loading ...; fig 10
Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; fig 5f
Cao B, Luo L, Feng L, Ma S, Chen T, Ren Y, et al. A network-based predictive gene-expression signature for adjuvant chemotherapy benefit in stage II colorectal cancer. BMC Cancer. 2017;17:844 pubmed publisher
  • western blot; human; fig 5
Lee J, Jung H, Han Y, Yoon Y, Yun C, Sun H, et al. Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells. Mol Med Rep. 2016;14:3777-84 pubmed publisher
  • western blot; human; fig 3
Jiang P, Wang P, Sun X, Yuan Z, Zhan R, Ma X, et al. Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy. Onco Targets Ther. 2016;9:3501-9 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Jeong J, Noh M, Choi J, Lee H, Kim S. Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons. Exp Ther Med. 2016;11:1201-1210 pubmed
  • western blot; human; 1:500; fig 4
Montes M, Coiras M, Becerra S, Moreno Castro C, Mateos E, Majuelos J, et al. Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing. PLoS ONE. 2015;10:e0139812 pubmed publisher
  • western blot; human; 1:200; fig 6
Hao W, Yuan X, Yu L, Gao C, Sun X, Wang D, et al. Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways. Sci Rep. 2015;5:10336 pubmed publisher
  • western blot; human; 1:200; fig 1c
Popp M, Maquat L. Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics. Nat Commun. 2015;6:6632 pubmed publisher
Shin D, Jo J, Choi M, Kim K, Bae Y, Kim S. Oncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer. Exp Mol Med. 2023;55:2220-2237 pubmed publisher
Chuang C, Wang M, Yeh J, Chen T, Tsou S, Lee Y, et al. The Protective Effects of α-Mangostin Attenuate Sodium Iodate-Induced Cytotoxicity and Oxidative Injury via Mediating SIRT-3 Inactivation via the PI3K/AKT/PGC-1α Pathway. Antioxidants (Basel). 2021;10: pubmed publisher
al Yacoub N, Colak D, Mahmoud S, Hammonds M, Muhammed K, Al Harazi O, et al. Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis. Commun Biol. 2021;4:884 pubmed publisher
Hsu J, Lin H, Chyau C, Wang Z, Chen J. Aqueous Extract of Pepino Leaves Ameliorates Palmitic Acid-Induced Hepatocellular Lipotoxicity via Inhibition of Endoplasmic Reticulum Stress and Apoptosis. Antioxidants (Basel). 2021;10: pubmed publisher
Liu R, Tan J, Shen X, Jiang K, Wang C, Zhu G, et al. Therapeutic targeting of FOS in mutant TERT cancers through removing TERT suppression of apoptosis via regulating survivin and TRAIL-R2. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Al Khayal K, Vaali Mohammed M, Elwatidy M, Bin Traiki T, Al Obeed O, Azam M, et al. A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway. BMC Cancer. 2020;20:685 pubmed publisher
Tu Z, Tan X, Li S, Cui J, Tu S, Jiang L. The therapeutic effect of controlled reoxygenation on chronic hypoxia-associated brain injury. Biol Open. 2019;8: pubmed publisher
Liu L, Yang J, Ji W, Wang C. Curcumin Inhibits Proliferation of Epstein-Barr Virus-Associated Human Nasopharyngeal Carcinoma Cells by Inhibiting EBV Nuclear Antigen 1 Expression. Biomed Res Int. 2019;2019:8592921 pubmed publisher
Musumeci G, Castrogiovanni P, Loreto C, Castorina S, Pichler K, Weinberg A. Post-traumatic caspase-3 expression in the adjacent areas of growth plate injury site: a morphological study. Int J Mol Sci. 2013;14:15767-84 pubmed publisher
Sen S, Kawahara B, Chaudhuri G. Maintenance of higher H?O? levels, and its mechanism of action to induce growth in breast cancer cells: important roles of bioactive catalase and PP2A. Free Radic Biol Med. 2012;53:1541-51 pubmed publisher
Chen Y, Guo H, Du Z, Liu X, Che Y, Ye X. Ecology-based screen identifies new metabolites from a Cordyceps-colonizing fungus as cancer cell proliferation inhibitors and apoptosis inducers. Cell Prolif. 2009;42:838-47 pubmed publisher
product information
Catalog Number :
sc-56196
Product Name :
cleaved PARP-1 (194C1439) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Antigen Modification :
cleaved
Clone Name :
194C1439
Isotype :
IgG2b
Size :
50 µg/0.5 ml
List Price :
316 USD
Immunogen :
PARP-1
Specificity :
mouse, rat, human
Uses :
WB, IP
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA