product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
NOXA (114C307) Antibody
catalog :
sc-56169
quantity :
50 µg/0.5 ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
114C307
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4
Twardziok M, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, et al. Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma. PLoS ONE. 2016;11:e0159749 pubmed publisher
  • western blot; human; fig 3
O Neill K, Huang K, Zhang J, Chen Y, Luo X. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973-88 pubmed publisher
  • western blot; human; 1:500; tbl 1
Vega Naredo I, Cunha Oliveira T, Serafim T, Sardao V, Oliveira P. Analysis of pro-apoptotic protein trafficking to and from mitochondria. Methods Mol Biol. 2015;1241:163-80 pubmed publisher
Huang K, O Neill K, Li J, Zhou W, Han N, Pang X, et al. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis. Cell Res. 2019;29:942-952 pubmed publisher
Zhao J, Wozniak A, Adams A, Cox J, Vittal A, Voss J, et al. SIRT7 regulates hepatocellular carcinoma response to therapy by altering the p53-dependent cell death pathway. J Exp Clin Cancer Res. 2019;38:252 pubmed publisher
Soderquist R, Crawford L, Liu E, Lu M, Agarwal A, Anderson G, et al. Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity. Nat Commun. 2018;9:3513 pubmed publisher
Ishida C, Zhang Y, Bianchetti E, Shu C, Nguyen T, Kleiner G, et al. Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastoma. Clin Cancer Res. 2018;24:5392-5406 pubmed publisher
Sirtl S, Knoll G, Trinh D, Lang I, Siegmund D, Gross S, et al. Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors. Oncogene. 2018;37:4122-4136 pubmed publisher
Hanse E, Ruan C, Kachman M, Wang D, Lowman X, Kelekar A. Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer. Oncogene. 2017;36:3915-3924 pubmed publisher
Zhang Y, Shi C, Zhang H, Li G, Li S. MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma. Oncotarget. 2016;7:45263-45274 pubmed publisher
Bajpai R, Matulis S, Wei C, Nooka A, Von Hollen H, Lonial S, et al. Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax. Oncogene. 2016;35:3955-64 pubmed publisher
Yan J, Zhong N, Liu G, Chen K, Liu X, Su L, et al. Usp9x- and Noxa-mediated Mcl-1 downregulation contributes to pemetrexed-induced apoptosis in human non-small-cell lung cancer cells. Cell Death Dis. 2014;5:e1316 pubmed publisher
Ishii T, Seike T, Nakashima T, Jüliger S, Maharaj L, Soga S, et al. Anti-tumor activity against multiple myeloma by combination of KW-2478, an Hsp90 inhibitor, with bortezomib. Blood Cancer J. 2012;2:e68 pubmed publisher
product information
Catalog Number :
sc-56169
Product Name :
NOXA (114C307) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
114C307
Isotype :
IgG1
Size :
50 µg/0.5 ml
List Price :
316 USD
Immunogen :
NOXA
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA