| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 4e
| Li Y, Hu J, Cheng C, Xu F, Au R, Zhu L, et al. Baicalin Ameliorates DSS-Induced Colitis by Protecting Goblet Cells through Activating NLRP6 Inflammasomes. Evid Based Complement Alternat Med. 2022;2022:2818136 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 7e
| Cheng Q, Ding H, Fang J, Fang X, Liu H, Wang J, et al. Aquaporin 9 Represents a Novel Target of Chronic Liver Injury That May Antagonize Its Progression by Reducing Lipotoxicity. Oxid Med Cell Longev. 2021;2021:5653700 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 6c
| Albino A, Zambom F, Foresto Neto O, Oliveira K, Ávila V, Arias S, et al. Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis. Front Physiol. 2021;12:606392 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 2a
| Lee C, Chen W, Chen S, Lee T. Taurine Alleviates Sympathetic Innervation by Inhibiting NLRP3 Inflammasome in Postinfarcted Rats. J Cardiovasc Pharmacol. 2021;77:745-755 pubmed publisher |
- western blot; mouse; 1:200; loading ...; fig 2a
| Su Y, Wang Y, Liu M, Chen H. Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition. Mol Med Rep. 2021;24: pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 5f
| Hu J, Zhu Z, Ying H, Yao J, Ma H, Li L, et al. Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice. Front Pharmacol. 2020;11:605065 pubmed publisher |
- western blot; mouse; 1:3000; loading ...; fig 6c
| Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed publisher |
- western blot; human; loading ...; fig 3d
| Choi Y, Kim S, Choi Y, Nielsen T, Yan J, Lu A, et al. SERPINB1-mediated checkpoint of inflammatory caspase activation. Nat Immunol. 2019;20:276-287 pubmed publisher |
- immunohistochemistry; mouse; 1 ug/ml; loading ...; fig 3b
| Bian F, Xiao Y, Zaheer M, Volpe E, Pflugfelder S, Li D, et al. Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn. Int J Mol Sci. 2017;18: pubmed publisher |
- western blot; mouse; 1:200; fig 3
| Zhou L, Zheng Y, Li Z, Bao L, Dou Y, Tang Y, et al. Compound K Attenuates the Development of Atherosclerosis in ApoE(-/-) Mice via LXR? Activation. Int J Mol Sci. 2016;17: pubmed publisher |
- western blot; mouse; fig 2
| Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher |
- western blot; mouse; fig 6
| Yao X, Carlson D, Sun Y, Ma L, Wolf S, Minei J, et al. Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. PLoS ONE. 2015;10:e0139416 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig 8
- western blot; mouse; 1:1000; fig 2c
- western blot; human; 1:1000; fig 2c
| Shipkowski K, Taylor A, Thompson E, Glista Baker E, Sayers B, Messenger Z, et al. An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1. PLoS ONE. 2015;10:e0128888 pubmed publisher |
- western blot; mouse; fig 5b
| Song L, Huang Y, Zhao M, Wang Z, Wang S, Sun H, et al. A critical role for hemolysin in Vibrio fluvialis-induced IL-1β secretion mediated by the NLRP3 inflammasome in macrophages. Front Microbiol. 2015;6:510 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3a
| Callaway J, Smith S, McKinnon K, de Silva A, Crowe J, Ting J. Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J Biol Chem. 2015;290:17306-20 pubmed publisher |
| Wang H, Hong L, Huang J, Jiang Q, Tao R, Tan C, et al. P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy. Cell Res. 2015;25:674-90 pubmed publisher |
- western blot; mouse; fig 2
- western blot; human; fig 2
| Cheng Y, Song L, Huang Y, Xiong Y, Zhang X, Sun H, et al. Effect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1β production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation. Immunology. 2015;145:258-67 pubmed publisher |
- western blot; mouse; fig 5
| Zhou H, Qu Z, Mossine V, Nknolise D, Li J, Chen Z, et al. Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells. PLoS ONE. 2014;9:e113531 pubmed publisher |
- western blot; rat; 1:1000
| Dirks Naylor A, Kouzi S, Bero J, Tran N, Yang S, Mabolo R. Effects of acute doxorubicin treatment on hepatic proteome lysine acetylation status and the apoptotic environment. World J Biol Chem. 2014;5:377-86 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Sutinen E, Korolainen M, Häyrinen J, Alafuzoff I, Petratos S, Salminen A, et al. Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells. Front Cell Neurosci. 2014;8:214 pubmed publisher |
| Park E, Na H, Song Y, Shin S, Kim Y, Chung J. Activation of NLRP3 and AIM2 inflammasomes by Porphyromonas gingivalis infection. Infect Immun. 2014;82:112-23 pubmed publisher |
| Arimoto K, Miyauchi S, Troutman T, Zhang Y, Liu M, Stoner S, et al. Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis. Nat Commun. 2023;14:251 pubmed publisher |
| Dong A, Yang Y, Jiang S, Yao X, Qi D, Mao C, et al. Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson's disease. Acta Pharmacol Sin. 2022;: pubmed publisher |
| Molagoda I, Athapaththu A, Choi Y, Park C, Jin C, Kang C, et al. Fisetin Inhibits NLRP3 Inflammasome by Suppressing TLR4/MD2-Mediated Mitochondrial ROS Production. Antioxidants (Basel). 2021;10: pubmed publisher |
| Cordaro M, Fusco R, D Amico R, Siracusa R, Peritore A, Gugliandolo E, et al. Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein. Antioxidants (Basel). 2020;9: pubmed publisher |
| Shu W, Guo Z, Li L, Xiong Z, Wang Z, Yang Y, et al. Regulation of Molecular Chaperone GRP78 by Hepatitis B Virus: Control of Viral Replication and Cell Survival. Mol Cell Biol. 2020;40: pubmed publisher |
| Xu F, Shen G, Su Z, He Z, Yuan L. Glibenclamide ameliorates the disrupted blood-brain barrier in experimental intracerebral hemorrhage by inhibiting the activation of NLRP3 inflammasome. Brain Behav. 2019;9:e01254 pubmed publisher |
| Tyagi A, Nguyen C, Chong T, Michel C, Fritz K, Reisdorph N, et al. SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain. Sci Rep. 2018;8:17547 pubmed publisher |
| Cheng C, Wu H, Wang M, Wang L, Zou H, Li S, et al. Estrogen ameliorates allergic airway inflammation by regulating activation of NLRP3 in mice. Biosci Rep. 2019;39: pubmed publisher |
| Wang S, Lin Y, Yuan X, Li F, Guo L, Wu B. REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis. Nat Commun. 2018;9:4246 pubmed publisher |
| Zhang S, Dong Y, Wang P, Zhang X, Yan Y, Sun L, et al. Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance. EBioMedicine. 2018;31:202-216 pubmed publisher |
| Hegde B, Bodduluri S, Satpathy S, Alghsham R, Jala V, Uriarte S, et al. Inflammasome-Independent Leukotriene B4 Production Drives Crystalline Silica-Induced Sterile Inflammation. J Immunol. 2018;200:3556-3567 pubmed publisher |
| Coates B, Staricha K, Koch C, Cheng Y, Shumaker D, Budinger G, et al. Inflammatory Monocytes Drive Influenza A Virus-Mediated Lung Injury in Juvenile Mice. J Immunol. 2018;200:2391-2404 pubmed publisher |
| Peeters P, Eurlings I, Perkins T, Wouters E, Schins R, Borm P, et al. Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs. Part Fibre Toxicol. 2014;11:58 pubmed publisher |
| Dirks Naylor A, Tran N, Yang S, Mabolo R, Kouzi S. The effects of acute doxorubicin treatment on proteome lysine acetylation status and apical caspases in skeletal muscle of fasted animals. J Cachexia Sarcopenia Muscle. 2013;4:239-43 pubmed publisher |
| Chen K, Zhang J, Zhang W, Zhang J, Yang J, Li K, et al. ATP-P2X4 signaling mediates NLRP3 inflammasome activation: a novel pathway of diabetic nephropathy. Int J Biochem Cell Biol. 2013;45:932-43 pubmed publisher |
| Lee H, Kang J, Lee S, Jo E. Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria. Glia. 2013;61:441-52 pubmed publisher |
| Zhang X, Cheng Y, Xiong Y, Ye C, Zheng H, Sun H, et al. Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1? in human macrophages and EHEC-induced IL-1? required activation of NLRP3 inflammasome. PLoS ONE. 2012;7:e50288 pubmed publisher |
| Wang Z, Yan J, Zheng Q, Wang Z, Li J, Zhang X, et al. Effects of biodegradable Mg-6Zn alloy extracts on cell cycle of intestinal epithelial cells. J Biomater Appl. 2013;27:739-47 pubmed publisher |
