Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; 1:1000; loading ...; fig 4a
| Russell J, Lu W, Okabe H, Abrams M, Oertel M, Poddar M, et al. Hepatocyte-Specific β-Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes. Hepatology. 2019;69:742-759 pubmed publisher
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- western blot knockout validation; human; loading ...; fig 1d
| Dietsch F, Donzeau M, Cordonnier A, Weiss E, Chatton B, Vigneron M. A fast method for analyzing essential protein mutants in human cells. Biotechniques. 2017;62:80-82 pubmed publisher
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- immunohistochemistry - paraffin section; dogs; 1:500; loading ...; fig 3a
| Hern xe1 ndez Jard xf3 n N, Rojas Casta xf1 eda J, Landero Huerta D, Reyes Cruz E, Reynoso Robles R, Ju xe1 rez Mosqueda M, et al. Cryptorchidism: The dog as a study model. Front Vet Sci. 2022;9:935307 pubmed publisher
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- western blot; human; loading ...; fig 4a
| Jiang L, Li D, Wang C, Liao J, Liu J, Wei Q, et al. Decreased Expression of Karyopherin-α 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells. Pathol Oncol Res. 2022;28:1610518 pubmed publisher
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- western blot; human; loading ...; fig 4a
| Mandic R, Marquardt A, Terhorst P, Ali U, Nowak Rossmann A, Cai C, et al. The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC. BMC Cancer. 2022;22:785 pubmed publisher
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- immunohistochemistry; zebrafish ; loading ...; fig 4g
| Coolen M, Altin N, Rajamani K, Pereira E, Siquier Pernet K, Puig Lombardi E, et al. Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cell differentiation. Am J Hum Genet. 2022;109:909-927 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:100; fig 1b
| Hatterschide J, Castagnino P, Kim H, Sperry S, Montone K, Basu D, et al. YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia. elife. 2022;11: pubmed publisher
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- western blot; mouse; loading ...; fig 6b
| Sun H, Ni H, McCracken J, Akakpo J, Fulte S, McKeen T, et al. Liver-specific deletion of mechanistic target of rapamycin does not protect against acetaminophen-induced liver injury in mice. Liver Res. 2021;5:79-87 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6b
| Tulotta C, Lefley D, Moore C, Amariutei A, Spicer Hadlington A, Quayle L, et al. IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer. NPJ Breast Cancer. 2021;7:95 pubmed publisher
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- immunocytochemistry; human; 1:1000; fig s7c
| Hatzopoulos G, Kükenshöner T, Banterle N, Favez T, Flückiger I, Hamel V, et al. Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun. 2021;12:3805 pubmed publisher
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- immunocytochemistry; human; 1:50; loading ...; fig 2g
| Prokakis E, Dyas A, Grün R, Fritzsche S, Bedi U, Kazerouni Z, et al. USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response. Oncogene. 2021;40:4004-4018 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3f
| Wang S, Li S, Li Y, Jiang Q, Li X, Wang Y, et al. Non-muscle myosin heavy chain 9 maintains intestinal homeostasis by preventing epithelium necroptosis and colitis adenoma formation. Stem Cell Reports. 2021;16:1290-1301 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 1b
- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s4c
- western blot; mouse; 1:500; loading ...; fig 3j
| Ryu Y, Lee D, Shim J, Park J, Kim Y, Choi S, et al. KY19382, a novel activator of Wnt/β-catenin signalling, promotes hair regrowth and hair follicle neogenesis. Br J Pharmacol. 2021;178:2533-2546 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1e
| Choi J, Sebastian C, Ferrer C, Lewis C, Sade Feldman M, LaSalle T, et al. A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma. Nat Metab. 2021;3:182-195 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig s3-4d
| Watts L, Natsume T, Saito Y, Garzón J, Dong Q, Boteva L, et al. The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress. elife. 2020;9: pubmed publisher
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- western blot; mouse; loading ...; fig 8
| Centrone M, Gena P, Ranieri M, Di Mise A, D Agostino M, Mastrodonato M, et al. In Vitro and In Vivo Nutraceutical Characterization of Two Chickpea Accessions: Differential Effects on Hepatic Lipid Over-Accumulation. Antioxidants (Basel). 2020;9: pubmed publisher
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- immunohistochemistry; mouse; loading ...
| Sanz Gómez N, de Pedro I, Ortigosa B, Santamaria D, Malumbres M, de Carcer G, et al. Squamous differentiation requires G2/mitosis slippage to avoid apoptosis. Cell Death Differ. 2020;27:2451-2467 pubmed publisher
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- western blot; human; loading ...; fig 1s1a
| Wutz G, Ladurner R, St Hilaire B, Stocsits R, Nagasaka K, Pignard B, et al. ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL. elife. 2020;9: pubmed publisher
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- western blot; human; loading ...; fig 6a
| Lai S, Lin H, Liu Y, Yang L, Lu D. Monocarboxylate Transporter 4 Regulates Glioblastoma Motility and Monocyte Binding Ability. Cancers (Basel). 2020;12: pubmed publisher
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- immunohistochemistry - paraffin section; rat; 1:800; loading ...; fig 9c
| Zhang Y, Mao X, Chen W, Guo X, Yu L, Jiang F, et al. A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation. Mol Ther Nucleic Acids. 2020;19:890-904 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig s8
| Famulari E, Navarro Tableros V, Herrera Sanchez M, Bortolussi G, Gai M, Conti L, et al. Human liver stem cells express UGT1A1 and improve phenotype of immunocompromised Crigler Najjar syndrome type I mice. Sci Rep. 2020;10:887 pubmed publisher
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- immunohistochemistry; mouse; 1:100; loading ...; fig 3d, 3e
| Li C, Chen W, Wang J, Xia M, Jia Z, Guo C, et al. Nicotinamide riboside rescues angiotensin II-induced cerebral small vessel disease in mice. CNS Neurosci Ther. 2020;26:438-447 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3d
| Francis R, Guo H, Streutker C, Ahmed M, Yung T, Dirks P, et al. Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. Sci Adv. 2019;5:eaax8898 pubmed publisher
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- western blot; human; loading ...; fig 2h
| Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, et al. CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle. Nature. 2019;: pubmed publisher
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- western blot; human; loading ...; fig 5e
| Xu M, Qin J, Wang L, Lee H, Kao C, Liu D, et al. Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019;5:eaax6366 pubmed publisher
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- western blot; human; loading ...; fig 7a
| Wessel S, Mohni K, Luzwick J, Dungrawala H, Cortez D. Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators. Cell Rep. 2019;28:3497-3509.e4 pubmed publisher
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- immunohistochemistry - paraffin section; Atlantic killifish; 1:100; loading ...; fig 4
| Szymkowicz D, Sims K, Schwendinger K, Tatnall C, Powell R, Bruce T, et al. Exposure to arsenic during embryogenesis impairs olfactory sensory neuron differentiation and function into adulthood. Toxicology. 2019;420:73-84 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 5a
| Han Y, Feng H, Sun J, Liang X, Wang Z, Xing W, et al. Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation. J Clin Invest. 2019;130: pubmed publisher
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- immunohistochemistry - paraffin section; human; loading ...; fig 1a
- western blot; human; 1:3000; loading ...; fig 1c
| Jeong W, Park J, Kim W, Ro E, Jeon S, Lee S, et al. WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation. Nat Commun. 2019;10:295 pubmed publisher
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- western blot; human; loading ...; fig 7i
| Xia J, Chiu L, Nehring R, Bravo Núñez M, Mei Q, Perez M, et al. Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Cell. 2019;176:127-143.e24 pubmed publisher
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- western blot; human; loading ...; fig 3d
| Moquin D, Genois M, Zhang J, Ouyang J, Yadav T, Buisson R, et al. Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination. Genes Dev. 2019;33:75-89 pubmed publisher
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- western blot; human; loading ...; fig 2b
| Mohni K, Wessel S, Zhao R, Wojciechowski A, Luzwick J, Layden H, et al. HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA. Cell. 2019;176:144-153.e13 pubmed publisher
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- immunocytochemistry; human; 1:500; loading ...; fig s1d
| Saldivar J, Hamperl S, Bocek M, Chung M, Bass T, Cisneros Soberanis F, et al. An intrinsic S/G2 checkpoint enforced by ATR. Science. 2018;361:806-810 pubmed publisher
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- western blot; mouse; loading ...; fig 1b
| Bornelöv S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, et al. The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression. Mol Cell. 2018;71:56-72.e4 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 4f
| Li M, Xu X, Chang C, Zheng L, Shen B, Liu Y. SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts. Nat Commun. 2018;9:2706 pubmed publisher
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- western blot; mouse; loading ...; fig s14e, s15f
- western blot; human; loading ...; fig 4f
| Ruess D, Heynen G, Ciecielski K, Ai J, Berninger A, Kabacaoglu D, et al. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018;24:954-960 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 4b
| Lei T, Zhang P, Zhang X, Xiao X, Zhang J, Qiu T, et al. Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation. Nat Commun. 2018;9:1876 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig 3a
- western blot; mouse; loading ...; fig 3b
| Park J, Kim I, Choi J, Lim H, Shin J, Kim Y, et al. AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development. Mol Cancer Res. 2018;16:1287-1298 pubmed publisher
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- western blot; mouse; loading ...; fig e10h
| Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed publisher
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- proximity ligation assay; mouse; fig 7d
| Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton S. Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell. 2018;172:439-453.e14 pubmed publisher
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- western blot; human; 1:2000; loading ...; fig 1d
| Somyajit K, Gupta R, Sedlackova H, Neelsen K, Ochs F, Rask M, et al. Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science. 2017;358:797-802 pubmed publisher
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- western blot; human; fig s3a
| Ong D, Hu B, Ho Y, Sauvé C, Bristow C, Wang Q, et al. PAF promotes stemness and radioresistance of glioma stem cells. Proc Natl Acad Sci U S A. 2017;114:E9086-E9095 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:5000; loading ...; fig 5f
- immunohistochemistry; mouse; 1:5000; loading ...; fig 5f
| Otto T, Candido S, Pilarz M, Sicinska E, Bronson R, Bowden M, et al. Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017;114:10660-10665 pubmed publisher
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- western blot; human; loading ...; fig 5
| Oblinger J, Burns S, Huang J, Pan L, Ren Y, Shen R, et al. Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation. Exp Neurol. 2018;299:299-307 pubmed publisher
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- western blot; human; loading ...; fig 1
| Bj Rås K, Sousa M, Sharma A, Fonseca D, S Gaard C, Bj Rås M, et al. Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication. Nucleic Acids Res. 2017;45:8291-8301 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig 3b
| Young C, Eckert R, Adhikary G, Crumrine D, Elias P, Blumenberg M, et al. Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like Phenotype. J Invest Dermatol. 2017;137:1868-1877 pubmed publisher
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- immunohistochemistry - paraffin section; human; fig 6c
| Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed publisher
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- immunohistochemistry; mouse; 1:500; loading ...; fig 5c
| Yuan X, Sun X, Shi X, Jiang C, Yu D, Zhang W, et al. USP39 regulates the growth of SMMC-7721 cells via FoxM1. Exp Ther Med. 2017;13:1506-1513 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:150; loading ...; fig 6a
| Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed publisher
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- western blot; human; loading ...; fig s10f
| Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed publisher
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- western blot; mouse; loading ...; fig 4c
| Martín Ibáñez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion Poll L, et al. Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017;144:1566-1577 pubmed publisher
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- western blot; human; loading ...; fig 4g
| Li K, Mo C, Gong D, Chen Y, Huang Z, Li Y, et al. DDX17 nucleocytoplasmic shuttling promotes acquired gefitinib resistance in non-small cell lung cancer cells via activation of β-catenin. Cancer Lett. 2017;400:194-202 pubmed publisher
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- immunohistochemistry - paraffin section; rat; loading ...; fig 4a
| Ibrahim M, Elwan W. Role of topical dehydroepiandrosterone in ameliorating isotretinoin-induced Meibomian gland dysfunction in adult male albino rat. Ann Anat. 2017;211:78-87 pubmed publisher
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- western blot; human; 1:2000; loading ...; fig 1d
| Maskey R, Flatten K, Sieben C, Peterson K, Baker D, Nam H, et al. Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis. Nucleic Acids Res. 2017;45:4564-4576 pubmed publisher
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- western blot; human; loading ...; fig 1c
| Liu Z, Yanagisawa K, Griesing S, Iwai M, Kano K, Hotta N, et al. TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas. Oncogene. 2017;36:3740-3748 pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig 6F
| Tu Y, Liu H, Zhu X, Shen H, Ma X, Wang F, et al. Ataxin-3 promotes genome integrity by stabilizing Chk1. Nucleic Acids Res. 2017;45:4532-4549 pubmed publisher
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- western blot; mouse; loading ...; fig 1e
| Ren W, Yin J, Xiao H, Chen S, Liu G, Tan B, et al. Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli Infection. Front Immunol. 2016;7:685 pubmed publisher
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- western blot; rat; loading ...; fig 1a
| Shi N, Li C, Cui X, Tomarev S, Chen S. Olfactomedin 2 Regulates Smooth Muscle Phenotypic Modulation and Vascular Remodeling Through Mediating Runt-Related Transcription Factor 2 Binding to Serum Response Factor. Arterioscler Thromb Vasc Biol. 2017;37:446-454 pubmed publisher
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- western blot; human; 1:3000; loading ...; fig s1a
| Mórocz M, Zsigmond E, Toth R, Enyedi M, Pintér L, Haracska L. DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA. Nucleic Acids Res. 2017;45:3172-3188 pubmed publisher
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- dot blot; human; 1:5000; loading ...; fig 2a
| Li C, Miao Y, Lingeman R, Hickey R, Malkas L. Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis. PLoS ONE. 2016;11:e0169259 pubmed publisher
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- western blot; human; loading ...; fig 3a
| Jo U, Cai W, Wang J, Kwon Y, D Andrea A, Kim H. PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress. PLoS Genet. 2016;12:e1006465 pubmed publisher
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- immunocytochemistry; human; 1:500; loading ...; fig 4a
- western blot; human; 1:4000; loading ...; fig 1b
| Despras E, Sittewelle M, Pouvelle C, Delrieu N, Cordonnier A, Kannouche P. Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. Nat Commun. 2016;7:13326 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 4a
| Wu R, Wang Z, Zhang H, Gan H, Zhang Z. H3K9me3 demethylase Kdm4d facilitates the formation of pre-initiative complex and regulates DNA replication. Nucleic Acids Res. 2017;45:169-180 pubmed publisher
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- western blot; human; fig 2b
| Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
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- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3
| Gao Y, Li J, Qiao N, Meng Q, Zhang M, Wang X, et al. Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway. Oncotarget. 2016;7:63374-63387 pubmed publisher
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- western blot; human; loading ...; fig 6a
| Urban V, Dobrovolna J, Huhn D, Fryzelkova J, Bartek J, Janscak P. RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells. J Cell Biol. 2016;214:401-15 pubmed publisher
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- western blot; human; fig 8
| Engel N, Ali I, Adamus A, Frank M, Dad A, Ali S, et al. Antitumor evaluation of two selected Pakistani plant extracts on human bone and breast cancer cell lines. BMC Complement Altern Med. 2016;16:244 pubmed publisher
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- western blot; human; loading ...; fig 5c
| Chen C, Tsao N, Huang L, Yen Y, Liu X, Lehman C, et al. The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells. Cell Rep. 2016;16:1287-1299 pubmed publisher
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- western blot; human; 1:200; fig 3
| Yang C, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, et al. Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. Nat Commun. 2016;7:12135 pubmed publisher
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- western blot; human; 1:500; fig 3
| Gao Y, Mutter Rottmayer E, Greenwalt A, Goldfarb D, Yan F, Yang Y, et al. A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis. Nat Commun. 2016;7:12105 pubmed publisher
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- western blot; human; 1:1000; fig 1
| Guan C, Zhang J, Zhang J, Shi H, Ni R. Enhanced expression of early mitotic inhibitor-1 predicts a poor prognosis in esophageal squamous cell carcinoma patients. Oncol Lett. 2016;12:114-120 pubmed
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- immunohistochemistry; mouse; 1:100; fig 1
| Barrionuevo F, Hurtado A, Kim G, Real F, Bakkali M, Kopp J, et al. Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. elife. 2016;5: pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1d
| Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed publisher
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- western blot; human; 1:200; loading ...; fig 2a
| Wisnovsky S, Jean S, Kelley S. Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes. Nat Chem Biol. 2016;12:567-73 pubmed publisher
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- western blot; human; loading ...; fig 1a
| Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher
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- western blot; chicken; fig s6
| Romanello M, Schiavone D, Frey A, Sale J. Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA. EMBO J. 2016;35:1452-64 pubmed publisher
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- western blot; pigs ; fig 6
| Ren W, Yin J, Chen S, Duan J, Liu G, Li T, et al. Proteome analysis for the global proteins in the jejunum tissues of enterotoxigenic Escherichia coli -infected piglets. Sci Rep. 2016;6:25640 pubmed publisher
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- western blot; mouse; fig s1
| Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed publisher
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- immunohistochemistry - free floating section; rat; 1:250; loading ...; fig 2a
| Mohr M, Garcia F, Doncarlos L, Sisk C. Neurons and Glial Cells Are Added to the Female Rat Anteroventral Periventricular Nucleus During Puberty. Endocrinology. 2016;157:2393-402 pubmed publisher
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- immunohistochemistry; Japanese rice fish; 1:500; fig 3
| Lust K, Sinn R, Pérez Saturnino A, Centanin L, Wittbrodt J. De novo neurogenesis by targeted expression of atoh7 to Müller glia cells. Development. 2016;143:1874-83 pubmed publisher
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- western blot; human; loading ...; fig 1b
| Macritchie N, Volpert G, Al Washih M, Watson D, Futerman A, Kennedy S, et al. Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodelling in a hypoxic model of pulmonary arterial hypertension. Cell Signal. 2016;28:946-55 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5e
| Yin Y, Ren X, Smith C, Guo Q, Malabunga M, Guernah I, et al. Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody. Dis Model Mech. 2016;9:563-71 pubmed publisher
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- immunohistochemistry - frozen section; mouse; fig 3
| Seidel P, Remus M, Delacher M, Grigaravicius P, Reuss D, Frappart L, et al. Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis. Oncotarget. 2016;7:23006-18 pubmed publisher
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- western blot; mouse; 1:1000; fig 4
| Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Przedborski S, Mochizuki H, et al. Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 2016;7:10943 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5g
- western blot; mouse; 1:100; loading ...; fig 5d
| Zhao H, Wang H, Bauzon F, Lu Z, Fu H, Cui J, et al. Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis. J Biol Chem. 2016;291:10201-9 pubmed publisher
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- western blot; human; fig 1a
| Kemp M, Sancar A. ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress. J Biol Chem. 2016;291:9330-42 pubmed publisher
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- western blot; human; fig 6
| Wu G, Zeng G. METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells. BMC Cancer. 2016;16:136 pubmed publisher
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- immunocytochemistry; human; 1:1000; fig 5b
| Walter D, Hoffmann S, Komseli E, Rappsilber J, Gorgoulis V, Sørensen C. SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication. Nat Commun. 2016;7:10530 pubmed publisher
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- immunohistochemistry; human; 1:200; fig 4
| Stefanovic M, Tutusaus A, Martinez Nieto G, Bárcena C, de Gregorio E, Moutinho C, et al. Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma. Oncotarget. 2016;7:8253-67 pubmed publisher
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- western blot; human; 1:1000; fig 1
| Wang Z, Huang M, Ma X, Li H, Tang T, Guo C. REV1 promotes PCNA monoubiquitylation through interacting with ubiquitylated RAD18. J Cell Sci. 2016;129:1223-33 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 7c
| Park K, Yun H, Quang T, Oh H, Lee D, Auh Q, et al. 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway. Oncotarget. 2016;7:6960-71 pubmed publisher
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- immunocytochemistry; human; 1:100; fig 1
- western blot; human; fig 2
| Benatti P, Belluti S, Miotto B, Neusiedler J, Dolfini D, Drac M, et al. Direct non transcriptional role of NF-Y in DNA replication. Biochim Biophys Acta. 2016;1863:673-85 pubmed publisher
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- immunocytochemistry; human; fig 1
- western blot; human; fig 1
| Hoffmann S, Smedegaard S, Nakamura K, Mortuza G, Räschle M, Ibañez de Opakua A, et al. TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J Cell Biol. 2016;212:63-75 pubmed publisher
|
- immunohistochemistry; rat; fig 2
| Bishayee A, Mandal A, Bhattacharyya P, Bhatia D. Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis. Nutr Cancer. 2016;68:120-30 pubmed publisher
|
- immunohistochemistry; mouse; fig 5
| Egan C, Sodhi C, Good M, Lin J, Jia H, Yamaguchi Y, et al. Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis. J Clin Invest. 2016;126:495-508 pubmed
|
- proximity ligation assay; human; 1:500; fig 3
- immunocytochemistry; human; 1:400; fig 3
| Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed publisher
|
- immunohistochemistry; tiger salamander; 1:400; fig 2
| Rodrigo Albors A, Tazaki A, Rost F, Nowoshilow S, Chara O, Tanaka E. Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration. elife. 2015;4:e10230 pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig 2e
| Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed publisher
|
- immunohistochemistry; mouse; 1:1000; fig 3
| Wang Z, Kim J, Teng Y, Ding H, Zhang J, Hai T, et al. Loss of ATF3 promotes hormone-induced prostate carcinogenesis and the emergence of CK5(+)CK8(+) epithelial cells. Oncogene. 2016;35:3555-64 pubmed publisher
|
- immunohistochemistry - paraffin section; mouse; fig s1
| Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher
|
- western blot; human; fig 7
| Graindorge D, Martineau S, Machon C, Arnoux P, Guitton J, Francesconi S, et al. Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLoS ONE. 2015;10:e0140645 pubmed publisher
|
- immunohistochemistry; human; fig 3
| Chou C, Chen S, Shun C, Tsao P, Yang Y, Yang J. Divergent endometrial inflammatory cytokine expression at peri-implantation period and after the stimulation by copper intrauterine device. Sci Rep. 2015;5:15157 pubmed publisher
|
- western blot; human; fig 8
| Yao M, Xie C, Kiang M, Teng Y, Harman D, Tiffen J, et al. Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells. Oncotarget. 2015;6:34458-74 pubmed publisher
|
- western blot; human; 1:1000; fig 7c
| Raman M, Sergeev M, Garnaas M, Lydeard J, Huttlin E, Goessling W, et al. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nat Cell Biol. 2015;17:1356-69 pubmed publisher
|
- western blot; rat; 1:1000; fig 2
| Forrest C, McNair K, Pisar M, Khalil O, Darlington L, Stone T. Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine. Neuroscience. 2015;310:91-105 pubmed publisher
|
- immunohistochemistry - paraffin section; human; fig 6b
| Vennin C, Spruyt N, Dahmani F, Julien S, Bertucci F, Finetti P, et al. H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b. Oncotarget. 2015;6:29209-23 pubmed publisher
|
- western blot; human; fig 6
| Qi D, Wang Q, Li H, Zhang T, Lan R, Kwong D, et al. SILAC-based quantitative proteomics identified lysosome as a fast response target to PDT agent Gd-N induced oxidative stress in human ovarian cancer IGROV1 cells. Mol Biosyst. 2015;11:3059-67 pubmed publisher
|
- immunohistochemistry; mouse; 1:200; fig 5
| Davila J, Laws M, Kannan A, Li Q, Taylor R, Bagchi M, et al. Rac1 Regulates Endometrial Secretory Function to Control Placental Development. PLoS Genet. 2015;11:e1005458 pubmed publisher
|
- immunohistochemistry - frozen section; mouse; 1:500
| Shimada M, Dumitrache L, Russell H, McKinnon P. Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability. EMBO J. 2015;34:2465-80 pubmed publisher
|
- immunohistochemistry - paraffin section; mouse; 1:200; fig 6
- western blot; mouse; fig 6
| Lee S, Kim J, Hong S, Lee A, Park E, Seo H, et al. High Inorganic Phosphate Intake Promotes Tumorigenesis at Early Stages in a Mouse Model of Lung Cancer. PLoS ONE. 2015;10:e0135582 pubmed publisher
|
| Akbari M, Sykora P, Bohr V. Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells. Sci Rep. 2015;5:12876 pubmed publisher
|
| Succoio M, Comegna M, D Ambrosio C, Scaloni A, Cimino F, Faraonio R. Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence. J Proteomics. 2015;128:18-29 pubmed publisher
|
- immunohistochemistry - paraffin section; human; 1:100; fig 3
| Giopanou I, Lilis I, Papaleonidopoulos V, Marazioti A, Spella M, Vreka M, et al. Comprehensive Evaluation of Nuclear Factor-κΒ Expression Patterns in Non-Small Cell Lung Cancer. PLoS ONE. 2015;10:e0132527 pubmed publisher
|
- western blot; mouse; 1:1000
| Szwarc M, Kommagani R, Jacob A, Dougall W, Ittmann M, Lydon J. Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors. PLoS ONE. 2015;10:e0128467 pubmed publisher
|
- western blot; human; fig 4
| Xu Y, Wu X, Her C. hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ. J Biol Chem. 2015;290:18545-58 pubmed publisher
|
| Kurppa K, Denessiouk K, Johnson M, Elenius K. Activating ERBB4 mutations in non-small cell lung cancer. Oncogene. 2016;35:1283-91 pubmed publisher
|
- immunohistochemistry - paraffin section; rat; fig 6
| Li P, Sheu M, Ma W, Pan C, Sheu J, Wu C. Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells. Mar Drugs. 2015;13:3046-60 pubmed publisher
|
- western blot; mouse; 1:1000; loading ...; fig 2b
| Yang Z, Zheng B, Zhang Y, He M, Zhang X, Ma D, et al. miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells. Biochim Biophys Acta. 2015;1852:1477-89 pubmed publisher
|
- western blot; human; 1:1000; fig 6
| Chen Y, Li X, Guo L, Wu X, He C, Zhang S, et al. Combining radiation with autophagy inhibition enhances suppression of tumor growth and angiogenesis in esophageal cancer. Mol Med Rep. 2015;12:1645-52 pubmed publisher
|
- western blot; rat; 1:10,000; fig 2
- western blot; human; 1:10,000; fig 2
| Chong L, Hsu Y, Lee T, Lin Y, Chiu Y, Yang K, et al. Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells. BMC Gastroenterol. 2015;15:22 pubmed publisher
|
| Markkanen E, Fischer R, Ledentcova M, Kessler B, Dianov G. Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability. Nucleic Acids Res. 2015;43:3667-79 pubmed publisher
|
- immunocytochemistry; mouse
| Williams J, Ni H, Haynes A, Manley S, Li Y, Jaeschke H, et al. Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice. J Biol Chem. 2015;290:10934-46 pubmed publisher
|
| Yan H, Solozobova V, Zhang P, Armant O, Kuehl B, Brenner Weiss G, et al. p53 is active in murine stem cells and alters the transcriptome in a manner that is reminiscent of mutant p53. Cell Death Dis. 2015;6:e1662 pubmed publisher
|
- immunocytochemistry; human; 1:100
| Rondinelli B, Schwerer H, Antonini E, Gaviraghi M, Lupi A, Frenquelli M, et al. H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing. Nucleic Acids Res. 2015;43:2560-74 pubmed publisher
|
- western blot; human; fig 3
| Jeong H, Gil N, Lee H, Cho S, Kim K, Chun K, et al. Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression. J Cell Biochem. 2015;116:1602-12 pubmed publisher
|
- immunohistochemistry; human; fig s3
| Gibbs Seymour I, Markiewicz E, Bekker Jensen S, Mailand N, Hutchison C. Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage. Aging Cell. 2015;14:162-9 pubmed publisher
|
- western blot; human; fig 1
| Ceccaldi R, Liu J, Amunugama R, Hajdu I, Primack B, Petalcorin M, et al. Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair. Nature. 2015;518:258-62 pubmed publisher
|
- western blot; human; 1:1000
| Shen Z, Stanger B. YAP regulates S-phase entry in endothelial cells. PLoS ONE. 2015;10:e0117522 pubmed publisher
|
- immunohistochemistry; mouse; 1:1000
| Jiang X, Ma T, Zhang Y, Zhang H, Yin S, Zheng W, et al. Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice. Biol Reprod. 2015;92:79 pubmed publisher
|
| Cai K, Wang Y, Smith E, Smedberg J, Yang D, Yang W, et al. Global deletion of Trp53 reverts ovarian tumor phenotype of the germ cell-deficient white spotting variant (Wv) mice. Neoplasia. 2015;17:89-100 pubmed publisher
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- immunohistochemistry; human; 1:100; fig 6
| Warnier M, Roudbaraki M, Derouiche S, Delcourt P, Bokhobza A, Prevarskaya N, et al. CACNA2D2 promotes tumorigenesis by stimulating cell proliferation and angiogenesis. Oncogene. 2015;34:5383-94 pubmed publisher
|
- western blot; human
- immunohistochemistry - paraffin section; mouse; fig 6
| Liu S, Lee W, Lai D, Wu S, Liu C, Tien H, et al. Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial-to-mesenchymal transition. Mol Oncol. 2015;9:834-49 pubmed publisher
|
- immunohistochemistry - paraffin section; human; 1:200; fig 7B
- western blot; mouse; fig 4A
| Bárcena C, Stefanovic M, Tutusaus A, Martinez Nieto G, Martinez L, GarcÃa Ruiz C, et al. Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer. Sci Rep. 2015;5:7916 pubmed publisher
|
- western blot; human; fig 6a
| Kehrli K, Sidorova J. Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells. Oncoscience. 2014;1:540-555 pubmed
|
- western blot; human; fig 3
| Butin Israeli V, Adam S, Jain N, Otte G, Neems D, Wiesmüller L, et al. Role of lamin b1 in chromatin instability. Mol Cell Biol. 2015;35:884-98 pubmed publisher
|
- immunohistochemistry - paraffin section; human
- western blot; human
| Li W, Ouyang Z, Zhang Q, Wang L, Shen Y, Gu Y, et al. SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2. Cell Death Dis. 2014;5:e1581 pubmed publisher
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- western blot; human; 1:1000; fig 4
| Bürgler S, Gimeno A, Parente Ribes A, Wang D, Os A, Devereux S, et al. Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism. J Immunol. 2015;194:827-35 pubmed publisher
|
- western blot; human; 1:2000; fig 5
| Bursomanno S, Beli P, Khan A, Minocherhomji S, Wagner S, Bekker Jensen S, et al. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. DNA Repair (Amst). 2015;25:84-96 pubmed publisher
|
- immunocytochemistry; mouse; 1:1000; fig 3
- western blot; mouse; 1:1000; fig 6
| Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed publisher
|
- western blot; human; 1:2000; fig s1b
| Fang Q, Inanç B, Schamus S, Wang X, Wei L, Brown A, et al. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β. Nat Commun. 2014;5:5513 pubmed publisher
|
- western blot; mouse; 1:2000; fig 7
| Tao W, Moore R, Smith E, Xu X. Hormonal induction and roles of Disabled-2 in lactation and involution. PLoS ONE. 2014;9:e110737 pubmed publisher
|
- western blot; human; 1:5000
| Arora R, Lee Y, Wischnewski H, Brun C, Schwarz T, Azzalin C. RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells. Nat Commun. 2014;5:5220 pubmed publisher
|
| Zhao X, Zhu L, Chang Q, Jiang C, You Y, Luo T, et al. C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation. J Biol Chem. 2014;289:30052-62 pubmed publisher
|
- immunocytochemistry; Japanese rice fish; 1:400
| Centanin L, Ander J, Hoeckendorf B, Lust K, Kellner T, Kraemer I, et al. Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina. Development. 2014;141:3472-82 pubmed publisher
|
| Carrillo Sepúlveda M, Keen H, Davis D, Grobe J, Sigmund C. Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. PLoS ONE. 2014;9:e103786 pubmed publisher
|
- immunohistochemistry; mouse; 1:3000
| Curto G, Nieto Estévez V, Hurtado Chong A, Valero J, Gómez C, Alonso J, et al. Pax6 is essential for the maintenance and multi-lineage differentiation of neural stem cells, and for neuronal incorporation into the adult olfactory bulb. Stem Cells Dev. 2014;23:2813-30 pubmed publisher
|
- immunohistochemistry; axolotl
| Zarzosa A, Grassme K, Tanaka E, Taniguchi Y, Bramke S, Kurth T, et al. Axolotls with an under- or oversupply of neural crest can regulate the sizes of their dorsal root ganglia to normal levels. Dev Biol. 2014;394:65-82 pubmed publisher
|
- immunohistochemistry; rat; 1:100
| Chen M, Huang Q, Xu W, She C, Xie Z, Mao Y, et al. Low-dose X-ray irradiation promotes osteoblast proliferation, differentiation and fracture healing. PLoS ONE. 2014;9:e104016 pubmed publisher
|
| Putiri E, Tiedemann R, Liu C, Choi J, Robertson K. Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome. Oncotarget. 2014;5:6338-52 pubmed
|
| Lo Sasso G, Ryu D, Mouchiroud L, Fernando S, Anderson C, Katsyuba E, et al. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS ONE. 2014;9:e102495 pubmed publisher
|
| Lin B, Gupta D, Heinen C. Human pluripotent stem cells have a novel mismatch repair-dependent damage response. J Biol Chem. 2014;289:24314-24 pubmed publisher
|
- immunohistochemistry; South American coati; 1:300
| Favaron P, Morini J, Mess A, Miglino M, Ambrosio C. Placentation and fetal membrane development in the South American coati, Nasua nasua (Mammalia, Carnivora, Procyonidae). Reprod Biol Endocrinol. 2014;12:57 pubmed publisher
|
- immunohistochemistry; chicken; 1:500; fig 1
| Herrera A, Saade M, Menendez A, Marti E, Pons S. Sustained Wnt/?-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. Nat Commun. 2014;5:4168 pubmed publisher
|
- western blot; human; fig 1
| Hayashi A, Suenaga N, Shiomi Y, Nishitani H. PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells. Methods Mol Biol. 2014;1170:367-82 pubmed publisher
|
| Chong H, Chan J, Goh C, Gounko N, Luo B, Wang X, et al. Angiopoietin-like 4 stimulates STAT3-mediated iNOS expression and enhances angiogenesis to accelerate wound healing in diabetic mice. Mol Ther. 2014;22:1593-604 pubmed publisher
|
| Chien P, Hsieh H, Chi P, Yang C. PAR1-dependent COX-2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytes. Br J Pharmacol. 2014;171:4504-19 pubmed publisher
|
- western blot; African green monkey
| Kim S, Lee S, Lee S, Park J, Ryu D. Arsenite-induced changes in hepatic protein abundance in cynomolgus monkeys (Macaca fascicularis). Proteomics. 2014;14:1833-43 pubmed publisher
|
- immunohistochemistry - frozen section; mouse; 1:500; fig 5a
| Katyal S, Lee Y, Nitiss K, Downing S, Li Y, Shimada M, et al. Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes. Nat Neurosci. 2014;17:813-21 pubmed publisher
|
| Akbari M, Keijzers G, Maynard S, Scheibye Knudsen M, Desler C, Hickson I, et al. Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair. DNA Repair (Amst). 2014;16:44-53 pubmed publisher
|
| Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed publisher
|
- immunohistochemistry; human; 1:40
| Hassan H, Varney M, Jain S, Weisenburger D, Singh R, Dave B. Disruption of chromosomal locus 1p36 differentially modulates TAp73 and ΔNp73 expression in follicular lymphoma. Leuk Lymphoma. 2014;55:2924-31 pubmed publisher
|
| Lee M, Wang L, Chang Z. The contribution of mitochondrial thymidylate synthesis in preventing the nuclear genome stress. Nucleic Acids Res. 2014;42:4972-84 pubmed publisher
|
- western blot; human; 1:500; fig s1a
| Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed publisher
|
- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human
| Chen M, Zhang Y, Yu V, Chong Y, Yoshioka T, Ge R. Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction. Cell Death Differ. 2014;21:797-810 pubmed publisher
|
| Liu F, Wang X, Hu G, Wang Y, Zhou J. The transcription factor TEAD1 represses smooth muscle-specific gene expression by abolishing myocardin function. J Biol Chem. 2014;289:3308-16 pubmed publisher
|
- immunohistochemistry; rat; 1:300
| Tseng M, Fu Q, Lor K, Fernandez Botran G, Deng Z, Graham U, et al. Persistent hepatic structural alterations following nanoceria vascular infusion in the rat. Toxicol Pathol. 2014;42:984-96 pubmed publisher
|
- western blot; human
- western blot; mouse
| Lee J, Park J, Kwon O, Kim H, Fornace A, Cha H. Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. J Dermatol Sci. 2014;73:125-34 pubmed publisher
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- immunohistochemistry; mouse; 1:100; fig 2
| Yin Y, Betsuyaku T, Garbow J, Miao J, Govindan R, Ornitz D. Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3. Cancer Res. 2013;73:5730-41 pubmed publisher
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- immunohistochemistry - free floating section; human; 1:500
| Dieriks B, Waldvogel H, Monzo H, Faull R, Curtis M. GABA(A) receptor characterization and subunit localization in the human sub-ventricular zone. J Chem Neuroanat. 2013;52:58-68 pubmed publisher
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| Wei Q, Li J, Liu T, Tong X, Ye X. Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem. 2013;288:19715-25 pubmed publisher
|
| Jin L, Craven R. The Rak/Frk tyrosine kinase associates with and internalizes the epidermal growth factor receptor. Oncogene. 2014;33:326-35 pubmed publisher
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- immunocytochemistry; human
| Culver Cochran A, Chadwick B. The WSTF-ISWI chromatin remodeling complex transiently associates with the human inactive X chromosome during late S-phase prior to BRCA1 and γ-H2AX. PLoS ONE. 2012;7:e50023 pubmed publisher
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- immunocytochemistry; human
| Solarczyk K, Zarebski M, Dobrucki J. Inducing local DNA damage by visible light to study chromatin repair. DNA Repair (Amst). 2012;11:996-1002 pubmed publisher
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| Svilar D, Dyavaiah M, Brown A, Tang J, Li J, McDonald P, et al. Alkylation sensitivity screens reveal a conserved cross-species functionome. Mol Cancer Res. 2012;10:1580-96 pubmed publisher
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- immunohistochemistry; human
| Restivo G, Nguyen B, Dziunycz P, Ristorcelli E, Ryan R, Özuysal Ö, et al. IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 2011;30:4571-85 pubmed publisher
|
| Tan M, Lim H, Harper J. SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation. Mol Cell Biol. 2011;31:3687-99 pubmed publisher
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| Cotta Ramusino C, McDonald E, Hurov K, Sowa M, Harper J, Elledge S. A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. Science. 2011;332:1313-7 pubmed publisher
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- western blot; human; 1:1000
| Benatti P, Dolfini D, Vigano A, Ravo M, Weisz A, Imbriano C. Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Nucleic Acids Res. 2011;39:5356-68 pubmed publisher
|
| Day T, Palle K, Barkley L, Kakusho N, Zou Y, Tateishi S, et al. Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication. J Cell Biol. 2010;191:953-66 pubmed publisher
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- immunocytochemistry; human
- western blot; human
| Schroering A, Williams K. Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment. DNA Repair (Amst). 2008;7:951-69 pubmed publisher
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| Funes J, Quintero M, Henderson S, Martinez D, Qureshi U, Westwood C, et al. Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. Proc Natl Acad Sci U S A. 2007;104:6223-8 pubmed
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- immunohistochemistry - free floating section; rat; 1:20,000
| Olariu A, Cleaver K, Cameron H. Decreased neurogenesis in aged rats results from loss of granule cell precursors without lengthening of the cell cycle. J Comp Neurol. 2007;501:659-67 pubmed
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| Bi X, Slater D, Ohmori H, Vaziri C. DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint. J Biol Chem. 2005;280:22343-55 pubmed
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| Nag J, Kancharla A, Maoz M, Turm H, Agranovich D, Gupta C, et al. Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated ?-catenin stabilization. Oncotarget. 2017;8:38650-38667 pubmed publisher
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| Di Pierdomenico J, García Ayuso D, Pinilla I, Cuenca N, Vidal Sanz M, Agudo Barriuso M, et al. Early Events in Retinal Degeneration Caused by Rhodopsin Mutation or Pigment Epithelium Malfunction: Differences and Similarities. Front Neuroanat. 2017;11:14 pubmed publisher
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| Alver R, Chadha G, Gillespie P, Blow J. Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1. Cell Rep. 2017;18:2508-2520 pubmed publisher
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| Saloura V, Vougiouklakis T, Zewde M, Deng X, Kiyotani K, Park J, et al. WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer. Sci Rep. 2017;7:40664 pubmed publisher
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| Prakash A, Moharana K, Wallace S, DOUBLIE S. Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase. Nucleic Acids Res. 2017;45:2897-2909 pubmed publisher
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| Lehmann M, Cooper H, Maric D, Herkenham M. Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages. J Neuroinflammation. 2016;13:224 pubmed publisher
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| Klein B, Mrowetz H, Thalhamer J, Scheiblhofer S, Weiss R, Aigner L. Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus. Front Cell Neurosci. 2016;10:169 pubmed publisher
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| Zhu L, Luo T, Xu X, Guo Y, Zhao X, Wang T, et al. E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor-mediated antifungal innate immunity. J Exp Med. 2016;213:1555-70 pubmed publisher
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| Ebine K, Chow C, DeCant B, Hattaway H, Grippo P, Kumar K, et al. Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia. Sci Rep. 2016;6:29133 pubmed publisher
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| Moura D, Fernández I, MarÃn Royo G, López Sánchez I, MartÃn Doncel E, Vega F, et al. Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. Sci Rep. 2016;6:28532 pubmed publisher
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| Parrilla M, León Lobera F, Lillo C, Arevalo R, Aijón J, Lara J, et al. Sox10 Expression in Goldfish Retina and Optic Nerve Head in Controls and after the Application of Two Different Lesion Paradigms. PLoS ONE. 2016;11:e0154703 pubmed publisher
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| Chagin V, Casas Delucchi C, Reinhart M, Schermelleh L, Markaki Y, Maiser A, et al. 4D Visualization of replication foci in mammalian cells corresponding to individual replicons. Nat Commun. 2016;7:11231 pubmed publisher
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| Yang Y, Poe J, Yang L, Fedoriw A, Desai S, Magnuson T, et al. Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo. Nucleic Acids Res. 2016;44:4174-88 pubmed publisher
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| Burkovics P, Dome L, Juhasz S, Altmannova V, Sebesta M, Pacesa M, et al. The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis. Nucleic Acids Res. 2016;44:3176-89 pubmed publisher
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| Biancardi M, Perez A, Caires C, Falleiros L, Góes R, Vilamaior P, et al. Prenatal and pubertal testosterone exposure imprint permanent modifications in the prostate that predispose to the development of lesions in old Mongolian gerbils. Asian J Androl. 2017;19:160-167 pubmed publisher
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| Kancharla A, Maoz M, Jaber M, Agranovich D, Peretz T, Grisaru Granovsky S, et al. PH motifs in PAR1&2 endow breast cancer growth. Nat Commun. 2015;6:8853 pubmed publisher
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| Shukla S, Shankar E, Fu P, MacLennan G, Gupta S. Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice. PLoS ONE. 2015;10:e0138710 pubmed publisher
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