product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ATRX (D-5) Antibody
catalog :
sc-55584
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-5
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:100; loading ...; fig s4a
Bressan R, Southgate B, Ferguson K, Blin C, Grant V, Alfazema N, et al. Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants. Cell Stem Cell. 2021;28:877-893.e9 pubmed publisher
  • western blot; human; 1:250; fig 4
Hahn A, Großkopf A, Jungnickl D, Scholz B, Ensser A. Viral FGARAT Homolog ORF75 of Rhesus Monkey Rhadinovirus Effects Proteasomal Degradation of the ND10 Components SP100 and PML. J Virol. 2016;90:8013-28 pubmed publisher
  • immunohistochemistry; human; 1:1000; fig 1
Leeper H, Caron A, Decker P, Jenkins R, LaChance D, Giannini C. IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas. Oncotarget. 2015;6:30295-305 pubmed publisher
  • chromatin immunoprecipitation; human; fig 2
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 3c
Eid R, Demattei M, Episkopou H, Augé Gouillou C, Decottignies A, Grandin N, et al. Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells. Mol Cell Biol. 2015;35:2818-30 pubmed publisher
Guthmann M, Qian C, Gialdini I, Nakatani T, Ettinger A, Schauer T, et al. A change in biophysical properties accompanies heterochromatin formation in mouse embryos. Genes Dev. 2023;37:336-350 pubmed publisher
Stilp A, Scherer M, K xf6 nig P, F xfc rstberger A, Kestler H, Stamminger T. The chromatin remodeling protein ATRX positively regulates IRF3-dependent type I interferon production and interferon-induced gene expression. PLoS Pathog. 2022;18:e1010748 pubmed publisher
Pladevall Morera D, Castejón Griñán M, Aguilera P, Gaardahl K, Ingham A, Brosnan Cashman J, et al. ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors. Cancers (Basel). 2022;14: pubmed publisher
Salsman J, Rapkin L, Margam N, Duncan R, Bazett Jones D, Dellaire G. Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres. Cell Death Dis. 2017;8:e2724 pubmed publisher
Pacurari M, Addison J, Bondalapati N, Wan Y, Luo D, Qian Y, et al. The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells. Int J Oncol. 2013;43:548-60 pubmed publisher
McFarlane S, Preston C. Human cytomegalovirus immediate early gene expression in the osteosarcoma line U2OS is repressed by the cell protein ATRX. Virus Res. 2011;157:47-53 pubmed publisher
product information
Catalog Number :
sc-55584
Product Name :
ATRX (D-5) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
D-5
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
ATRX
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA