product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Pol II (F-12) Antibody
catalog :
sc-55492
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-12
reactivity :
hamsters, human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4
Albert T, Antrecht C, Kremmer E, Meisterernst M. The Establishment of a Hyperactive Structure Allows the Tumour Suppressor Protein p53 to Function through P-TEFb during Limited CDK9 Kinase Inhibition. PLoS ONE. 2016;11:e0146648 pubmed publisher
  • chromatin immunoprecipitation; human; fig 5
  • western blot; human; fig 1
Lu H, Xue Y, Xue Y, Yu G, Arias C, Lin J, et al. Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism. elife. 2015;4:e06535 pubmed publisher
  • western blot; human; loading ...; fig 5a
Mayer A, Di Iulio J, Maleri S, Eser U, Vierstra J, Reynolds A, et al. Native elongating transcript sequencing reveals human transcriptional activity at nucleotide resolution. Cell. 2015;161:541-554 pubmed publisher
  • western blot; human
Ji X, Lu H, Zhou Q, Luo K. LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. elife. 2014;3:e02907 pubmed publisher
  • immunocytochemistry; hamsters
Akhrymuk I, Kulemzin S, Frolova E. Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II. J Virol. 2012;86:7180-91 pubmed publisher
Islam Z, Saravanan B, Walavalkar K, Farooq U, Singh A, Radhakrishnan S, et al. Active enhancers strengthen insulation by RNA-mediated CTCF binding at chromatin domain boundaries. Genome Res. 2023;33:1-17 pubmed publisher
Kalkat M, Resetca D, Lourenco C, Chan P, Wei Y, Shiah Y, et al. MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis. Mol Cell. 2018;72:836-848.e7 pubmed publisher
Nilson K, Lawson C, Mullen N, Ball C, Spector B, Meier J, et al. Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome. Nucleic Acids Res. 2017;45:11088-11105 pubmed publisher
Lu W, Katzenellenbogen B. Estrogen Receptor-? Modulation of the ER?-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast Cancer. Horm Cancer. 2017;8:230-242 pubmed publisher
Watanabe M, Takahashi H, Saeki Y, Ozaki T, Itoh S, Suzuki M, et al. The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ. elife. 2015;4:e05615 pubmed publisher
Tomita T, Ieguchi K, Coin F, Coin F, Kato Y, Kikuchi H, et al. ZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor. PLoS ONE. 2014;9:e108957 pubmed publisher
Galardi S, Mercatelli N, Farace M, Ciafrè S. NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells. Nucleic Acids Res. 2011;39:3892-902 pubmed publisher
product information
Catalog Number :
sc-55492
Product Name :
Pol II (F-12) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
F-12
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Pol II
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA