| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 2
| Taavela J, Viiri K, Välimäki A, Sarin J, Salonoja K, Maki M, et al. Apolipoprotein A4 Defines the Villus-Crypt Border in Duodenal Specimens for Celiac Disease Morphometry. Front Immunol. 2021;12:713854 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Jiao T, Yao X, Zhao Y, Zhou Y, Gao Y, Fan S, et al. Dexamethasone-Induced Liver Enlargement Is Related to PXR/YAP Activation and Lipid Accumulation but Not Hepatocyte Proliferation. Drug Metab Dispos. 2020;48:830-839 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Valanejad L, Lewis K, Wright M, Jiang Y, D Souza A, Karns R, et al. FXR-Gankyrin axis is involved in development of pediatric liver cancer. Carcinogenesis. 2017;38:738-747 pubmed publisher |
- western blot; human; loading ...; fig 6c
| Milkiewicz M, Klak M, Kempińska Podhorodecka A, Wiechowska Kozlowska A, Urasinska E, Blatkiewicz M, et al. Impaired Hepatic Adaptation to Chronic Cholestasis induced by Primary Sclerosing Cholangitis. Sci Rep. 2016;6:39573 pubmed publisher |
- western blot; human; loading ...; fig 6b
| Štěpánková M, Krasulová K, Doricakova A, Kurka O, Anzenbacher P, Dvorak Z. Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450. Toxicol Lett. 2016;262:173-186 pubmed publisher |
- western blot; human; fig 6
| Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, et al. Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance. Nat Commun. 2016;7:11030 pubmed publisher |
- western blot; human; 1:2000
| Smutny T, Bitman M, Urban M, Dubecka M, Vrzal R, Dvorak Z, et al. U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells. Arch Toxicol. 2014;88:2243-59 pubmed publisher |
| Miyauchi Y, Kimura A, Sawai M, Fujimoto K, Hirota Y, Tanaka Y, et al. Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4. Front Pharmacol. 2022;13:832931 pubmed publisher |
| Miyata S, Saku N, Akiyama S, Javaregowda P, Ite K, Takashima N, et al. Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI). Stem Cell Res Ther. 2022;13:6 pubmed publisher |
| Willis A, Indra R, Wohak L, Sozeri O, Feser K, Mrízová I, et al. The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. Toxicology. 2018;398-399:1-12 pubmed publisher |
| Korhonova M, Doricakova A, Dvorak Z. Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes. PLoS ONE. 2015;10:e0137720 pubmed publisher |
| Novotna A, Dvorak Z. Omeprazole and lansoprazole enantiomers induce CYP3A4 in human hepatocytes and cell lines via glucocorticoid receptor and pregnane X receptor axis. PLoS ONE. 2014;9:e105580 pubmed publisher |
| Dong M, Lee S, Kim H. Co-expression of human cytochrome b5 increases expression of cytochrome P450 3A4 in Escherichia coli by stabilizing mRNA. Protein Expr Purif. 2013;89:44-50 pubmed publisher |
| Li S, Li R, Xi S, Hu S, Jia Z, Li S, et al. Systematical analysis of impacts of heat stress on the proliferation, apoptosis and metabolism of mouse hepatocyte. J Physiol Sci. 2012;62:29-43 pubmed publisher |
| Novotna A, Doricakova A, Vrzal R, Pavek P, Dvorak Z. Construction and characterization of hepatocyte nuclear factor HNF4alpha1 over-expressing cell line derived from human hepatoma HepG2 cells. Eur J Pharmacol. 2011;669:45-50 pubmed publisher |
| Novotna A, Doricakova A, Vrzal R, Maurel P, Pavek P, Dvorak Z. Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells. Eur J Pharm Sci. 2010;41:276-80 pubmed publisher |
| Stock P, Brückner S, Ebensing S, Hempel M, Dollinger M, Christ B. The generation of hepatocytes from mesenchymal stem cells and engraftment into murine liver. Nat Protoc. 2010;5:617-27 pubmed publisher |
