product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
α Tubulin (10D8) Antibody
catalog :
sc-53646
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10D8
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 30
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 1g
Li H, Lian L, Liu B, Chen Y, Yang J, Jian S, et al. KIT ligand protects against both light-induced and genetic photoreceptor degeneration. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 2a
Jobin P, Solis N, Machado Y, Bell P, Kwon N, Kim S, et al. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. J Biol Chem. 2019;294:12866-12879 pubmed publisher
  • western blot; mouse; fig 2
Ren J, Li J, Liu X, Feng Y, Gui Y, Yang J, et al. Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling. Sci Rep. 2016;6:23968 pubmed publisher
  • western blot; human; 1:2000; fig 1
Rohrbach T, Shah N, Jackson W, Feeney E, Scanlon S, Gish R, et al. The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization. PLoS ONE. 2015;10:e0140870 pubmed publisher
  • western blot; mouse
Han Y, Choi Y, Lee S, Jin Y, Cheong H, Lee K. Yin Yang 1 is a multi-functional regulator of adipocyte differentiation in 3T3-L1 cells. Mol Cell Endocrinol. 2015;413:217-27 pubmed publisher
  • western blot; human
Chen S, Li D, Yang F, Wu Z, Zhao Y, Jiang Y. Gemcitabine-induced pancreatic cancer cell death is associated with MST1/cyclophilin D mitochondrial complexation. Biochimie. 2014;103:71-9 pubmed publisher
  • western blot; mouse; 1:1000
McDonel P, Demmers J, Tan D, Watt F, Hendrich B. Sin3a is essential for the genome integrity and viability of pluripotent cells. Dev Biol. 2012;363:62-73 pubmed publisher
Chang J, Yeh H, Park M, Erber L, Sun J, Cheng S, et al. mTOR-regulated U2af1 tandem exon splicing specifies transcriptome features for translational control. Nucleic Acids Res. 2019;47:10373-10387 pubmed publisher
Raghu D, Mobley R, Shendy N, Perry C, Abell A. GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells. Cell Rep. 2019;26:3684-3697.e7 pubmed publisher
Piya S, Mu H, Bhattacharya S, Lorenzi P, Davis R, McQueen T, et al. BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment. J Clin Invest. 2019;130: pubmed publisher
Eid W, Abdel Rehim W. Genome-wide analysis of ETV1 targets: Insights into the role of ETV1 in tumor progression. J Cell Biochem. 2019;120:8983-8991 pubmed publisher
Li B, Zhu X, Ward C, Starlard Davenport A, Takezaki M, Berry A, et al. MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease. Exp Hematol. 2019;70:85-96.e5 pubmed publisher
Xue X, Ren J, Sun X, Gui Y, Feng Y, Shu B, et al. Protein kinase Cα drives fibroblast activation and kidney fibrosis by stimulating autophagic flux. J Biol Chem. 2018;293:11119-11130 pubmed publisher
Belostotsky R, Lyakhovetsky R, Sherman M, Shkedy F, Tzvi Behr S, Bar R, et al. Translation inhibition corrects aberrant localization of mutant alanine-glyoxylate aminotransferase: possible therapeutic approach for hyperoxaluria. J Mol Med (Berl). 2018;96:621-630 pubmed publisher
Chang J, Zhang W, Yeh H, Park M, Yao C, Shi Y, et al. An integrative model for alternative polyadenylation, IntMAP, delineates mTOR-modulated endoplasmic reticulum stress response. Nucleic Acids Res. 2018;46:5996-6008 pubmed publisher
Gu H, Do D, Liu X, Xu L, Su Y, Nah J, et al. The STAT3 Target Mettl8 Regulates Mouse ESC Differentiation via Inhibiting the JNK Pathway. Stem Cell Reports. 2018;10:1807-1820 pubmed publisher
Sun W, Min B, Du D, Yang F, Meng J, Wang W, et al. miR-181c protects CsA-induced renal damage and fibrosis through inhibiting EMT. FEBS Lett. 2017;591:3588-3599 pubmed publisher
Cho H, Um J, Lee J, Kim W, Kang W, Kim S, et al. ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes. Sci Rep. 2017;7:44186 pubmed publisher
Zhou Y, Zhou Z, Zhang W, Hu X, Wei H, Peng J, et al. SIRT1 inhibits adipogenesis and promotes myogenic differentiation in C3H10T1/2 pluripotent cells by regulating Wnt signaling. Cell Biosci. 2015;5:61 pubmed publisher
Xu Z, Han Y, Liu J, Jiang F, Hu H, Wang Y, et al. MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C. Sci Rep. 2015;5:12276 pubmed publisher
Fan S, Liu B, Sun L, Lv X, Lin Z, Chen W, et al. Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p-MFF axis. Oncotarget. 2015;6:14885-904 pubmed
Feng C, Gao Y, Dorshorst B, Song C, Gu X, Li Q, et al. A cis-regulatory mutation of PDSS2 causes silky-feather in chickens. PLoS Genet. 2014;10:e1004576 pubmed publisher
Wang Y, Bettaieb A, Sun C, Deverse J, Radecke C, Mathew S, et al. Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress. PLoS ONE. 2013;8:e78322 pubmed publisher
Liu N, Xi Y, Callaghan M, Fribley A, Moore Smith L, Zimmerman J, et al. SMAD4 is a potential prognostic marker in human breast carcinomas. Tumour Biol. 2014;35:641-50 pubmed publisher
Mohamed J, Lopez M, Cox G, Boriek A. Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction. J Biol Chem. 2013;288:24560-8 pubmed publisher
Nowsheen S, Cooper T, Stanley J, Yang E. Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells. PLoS ONE. 2012;7:e46614 pubmed publisher
Nowsheen S, Bonner J, LoBuglio A, Trummell H, Whitley A, Dobelbower M, et al. Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer. PLoS ONE. 2011;6:e24148 pubmed publisher
Pan F, Zhang S, Xu N, Meng F, Zhang H, Xue B, et al. Beta-catenin signaling involves HGF-enhanced HepG2 scattering through activating MMP-7 transcription. Histochem Cell Biol. 2010;134:285-95 pubmed publisher
Box A, Kim S, Demetrick D. AKT loss in human epithelial cells treated with severe hypoxia. Biochim Biophys Acta. 2010;1803:951-9 pubmed publisher
Peng W, Pan F, Liu X, Ning S, Xu N, Meng F, et al. Hypoxia stabilizes microtubule networks and decreases tumor cell chemosensitivity to anticancer drugs through Egr-1. Anat Rec (Hoboken). 2010;293:414-20 pubmed publisher
product information
Catalog Number :
sc-53646
Product Name :
α Tubulin (10D8) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
10D8
Isotype :
IgM
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
alpha Tubulin
Specificity :
broad species
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA