| Published Application/Species/Sample/Dilution | Reference | 
|---|
| immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 6ewestern blot; human; 1:2000; loading ...; fig 6h
 | Pandey S, Shteinfer Kuzmine A, Chalifa Caspi V, Shoshan Barmatz V. Non-apoptotic activity of the mitochondrial protein SMAC/Diablo in lung cancer: Novel target to disrupt survival, inflammation, and immunosuppression. Front Oncol. 2022;12:992260 pubmed  publisher | 
| immunocytochemistry; mouse; 1:80; loading ...; fig 5a
 | Merlo S, Luaces J, Spampinato S, Toro Urrego N, Caruso G, D Amico F, et al . SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules. 2020;10: pubmed  publisher | 
| western blot; human; loading ...; fig 9d
 | Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed  publisher | 
| immunocytochemistry; human; 1:50; fig 2
 | Colombo J, Maciel J, Ferreira L, da Silva R, Zuccari D. Effects of melatonin on HIF-1? and VEGF expression and on the invasive properties of hepatocarcinoma cells. Oncol Lett. 2016;12:231-237 pubmed | 
| immunohistochemistry - paraffin section; mouse; 1:25; fig 3
 | Okawa H, Kayashima H, Sasaki J, Miura J, Kamano Y, Kosaka Y, et al . Scaffold-Free Fabrication of Osteoinductive Cellular Constructs Using Mouse Gingiva-Derived Induced Pluripotent Stem Cells. Stem Cells Int. 2016;2016:6240794 pubmed  publisher | 
| immunohistochemistry - paraffin section; human; 1:20; fig 1
 | Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L. Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer. PLoS ONE. 2016;11:e0146823 pubmed  publisher | 
| immunoprecipitation; human; 1:1000; fig 5western blot; human; 1:1000; fig 4
 | Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al . CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed  publisher | 
| western blot; human; fig 3
 | Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed | 
| western blot; human; fig 3
 | Yang L, Liu L, Xu Z, Liao W, Feng D, Dong X, et al . EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma. Oncotarget. 2015;6:5804-17 pubmed | 
| western blot; human; 1:500; fig 1
 | Yu C, Yang S, Fang X, Jiang J, Sun C, Huang T. Hypoxia disrupts the expression levels of circadian rhythm genes in hepatocellular carcinoma. Mol Med Rep. 2015;11:4002-8 pubmed  publisher | 
| immunocytochemistry; human; 1:50; fig 4
 | Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, et al . PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle. 2014;13:3878-91 pubmed  publisher | 
|  | Cannito S, Turato C, Paternostro C, Biasiolo A, Colombatto S, Cambieri I, et al . Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells. Oncotarget. 2015;6:2206-21 pubmed | 
| immunohistochemistry - paraffin section; human; loading ...; fig 4
 | Mazzatenta A, Marconi G, Zara S, Cataldi A, Porzionato A, Di Giulio C. In the carotid body, galanin is a signal for neurogenesis in young, and for neurodegeneration in the old and in drug-addicted subjects. Front Physiol. 2014;5:427 pubmed  publisher | 
| immunohistochemistry; rat; 1:100western blot; rat; 1:2000
 | Wu W, Tian R, Hao S, Xu F, Mao X, Liu B. A pre-injury high ethanol intake in rats promotes brain edema following traumatic brain injury. Br J Neurosurg. 2014;28:739-45 pubmed  publisher | 
|  | Aksu V, Yuksel V, Chousein S, Tastekin E, Iscan S, Sagiroglu G, et al . The effects of sildenafil and n-acetylcysteine on ischemia and reperfusion injury in gastrocnemius muscle and femoral artery endothelium. Vascular. 2015;23:21-30 pubmed  publisher | 
|  | Sun X, Fang B, Zhao X, Zhang G, Ma H. Preconditioning of mesenchymal stem cells by sevoflurane to improve their therapeutic potential. PLoS ONE. 2014;9:e90667 pubmed  publisher | 
| immunohistochemistry - paraffin section; human; 1:50; tbl 1
 | Maschio L, Madallozo B, Capellasso B, Jardim B, Moschetta M, Jampietro J, et al . Immunohistochemical investigation of the angiogenic proteins VEGF, HIF-1? and CD34 in invasive ductal carcinoma of the breast. Acta Histochem. 2014;116:148-57 pubmed  publisher | 
| immunohistochemistry - paraffin section; human; 1:100
 | Cao W, Kawai N, Miyake K, Zhang X, Fei Z, Tamiya T. Relationship of 14-3-3zeta (?), HIF-1?, and VEGF expression in human brain gliomas. Brain Tumor Pathol. 2014;31:1-10 pubmed  publisher | 
|  | Zhu J, Fu M, Gao J, Dai G, Guan Q, Du C. Upregulation of Thioredoxin Reductase 1 Expression by Flavan-3-Ols Protects Human Kidney Proximal Tubular Cells from Hypoxia-Induced Cell Death. Antioxidants (Basel). 2022;11: pubmed  publisher | 
|  | Xu S, Zhou Z, Peng X, Tao X, Zhou P, Zhang K, et al . EBV-LMP1 promotes radioresistance by inducing protective autophagy through BNIP3 in nasopharyngeal carcinoma. Cell Death Dis. 2021;12:344 pubmed  publisher | 
|  | Hock D, Reljic B, Ang C, Muellner Wong L, Mountford H, Compton A, et al . HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV. Mol Cell Proteomics. 2020;19:1145-1160 pubmed  publisher | 
|  | Seira N, Yamagata K, Fukushima K, Araki Y, Kurata N, Yanagisawa N, et al . Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region. Pharmacol Res Perspect. 2018;6:e00441 pubmed  publisher | 
|  | Batie M, Druker J, D Ignazio L, Rocha S. KDM2 Family Members are Regulated by HIF-1 in Hypoxia. Cells. 2017;6: pubmed  publisher | 
|  | Liu H, Jiang F, Jia X, Lan J, Guo H, Li E, et al . Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of P18 through claudin7. Oncotarget. 2017;8:10298-10311 pubmed  publisher | 
|  | Grewal N, Franken R, Mulder B, Goumans M, Lindeman J, Jongbloed M, et al . Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy?. Heart Vessels. 2016;31:795-806 pubmed  publisher | 
|  | Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze da Rocha E, Rocha Pereira P, et al . Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model. PLoS ONE. 2015;10:e0124048 pubmed  publisher | 
|  | Thomaidis T, Maderer A, Formentini A, Bauer S, Trautmann M, Schwarz M, et al . Proteins of the VEGFR and EGFR pathway as predictive markers for adjuvant treatment in patients with stage II/III colorectal cancer: results of the FOGT-4 trial. J Exp Clin Cancer Res. 2014;33:83 pubmed  publisher | 
|  | Marconi G, Zara S, De Colli M, Di Valerio V, Rapino M, Zaramella P, et al . Postnatal hyperoxia exposure differentially affects hepatocytes and liver haemopoietic cells in newborn rats. PLoS ONE. 2014;9:e105005 pubmed  publisher | 
|  | Wang Y, Huang Y, Guan F, Xiao Y, Deng J, Chen H, et al . Hypoxia-inducible factor-1alpha and MAPK co-regulate activation of hepatic stellate cells upon hypoxia stimulation. PLoS ONE. 2013;8:e74051 pubmed  publisher | 
|  | Holzer L, Cor A, Pfandlsteiner G, Holzer G. Expression of VEGF, its receptors, and HIF-1? in Dupuytren's disease. Acta Orthop. 2013;84:420-5 pubmed  publisher | 
|  | Reszec J, Hermanowicz A, Rutkowski R, Bernaczyk P, Mariak Z, Chyczewski L. Evaluation of mast cells and hypoxia inducible factor-1 expression in meningiomas of various grades in correlation with peritumoral brain edema. J Neurooncol. 2013;115:119-25 pubmed  publisher | 
|  | Talagas M, Uguen A, Garlantezec R, Fournier G, Doucet L, Gobin E, et al . VEGFR1 and NRP1 endothelial expressions predict distant relapse after radical prostatectomy in clinically localized prostate cancer. Anticancer Res. 2013;33:2065-75 pubmed | 
|  | Guven Bagla A, Ercan E, Asgun H, Ickin M, Ercan F, Yavuz O, et al . Experimental acute myocardial infarction in rats: HIF-1?, caspase-3, erythropoietin and erythropoietin receptor expression and the cardioprotective effects of two different erythropoietin doses. Acta Histochem. 2013;115:658-68 pubmed  publisher | 
|  | Han C, Sun B, Wang W, Cai W, Lou D, Sun Y, et al . A pilot study on morphology and the mechanism involved in linearly patterned programmed cell necrosis in melanoma. Oncol Lett. 2010;1:821-826 pubmed | 
|  | Chang C, Chio C, Cheong C, Chao C, Cheng B, Lin M. Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury. Clin Sci (Lond). 2013;124:165-76 pubmed  publisher | 
|  | Haligur M, Topsakal S, Ozmen O. Early degenerative effects of diabetes mellitus on pancreas, liver, and kidney in rats: an immunohistochemical study. Exp Diabetes Res. 2012;2012:120645 pubmed  publisher | 
|  | Iglesias P, Fraga M, Costoya J. Defining hypoxic microenvironments by non-invasive functional optical imaging. Eur J Cancer. 2013;49:264-71 pubmed  publisher | 
|  | Aydogdu O, Burgu B, Göçün P, Ozden E, Yaman O, Soygur T, et al . Near infrared spectroscopy to diagnose experimental testicular torsion: comparison with Doppler ultrasound and immunohistochemical correlation of tissue oxygenation and viability. J Urol. 2012;187:744-50 pubmed  publisher | 
|  | Deschene K, Celeste C, Boerboom D, Theoret C. Hypoxia regulates the expression of extracellular matrix associated proteins in equine dermal fibroblasts via HIF1. J Dermatol Sci. 2012;65:12-8 pubmed  publisher | 
|  | Morine Y, Shimada M, Iwahashi S, Utsunomiya T, Imura S, Ikemoto T, et al . Role of histone deacetylase expression in intrahepatic cholangiocarcinoma. Surgery. 2012;151:412-9 pubmed  publisher | 
|  | Shen G, Zhao Y, Chen M, Zhang F, Liu X, Wang Y, et al . Hypoxia-inducible factor-1 (HIF-1) promotes LDL and VLDL uptake through inducing VLDLR under hypoxia. Biochem J. 2012;441:675-83 pubmed  publisher | 
|  | Wang Z, Shi Q, Wang Z, Gu Y, Shen Y, Sun M, et al . Clinicopathologic correlation of cancer stem cell markers CD44, CD24, VEGF and HIF-1? in ductal carcinoma in situ and invasive ductal carcinoma of breast: an immunohistochemistry-based pilot study. Pathol Res Pract. 2011;207:505-13 pubmed  publisher | 
|  | Deschene K, Celeste C, Boerboom D, Theoret C. Constitutive expression of hypoxia-inducible factor-1 ? in keratinocytes during the repair of skin wounds in horses. Wound Repair Regen. 2011;19:250-9 pubmed  publisher | 
|  | Heindryckx F, Mertens K, Charette N, Vandeghinste B, Casteleyn C, Van Steenkiste C, et al . Kinetics of angiogenic changes in a new mouse model for hepatocellular carcinoma. Mol Cancer. 2010;9:219 pubmed  publisher | 
|  | Ying Wan -, Wu Y, Feng X, Lian L, Jiang Y, Nan J. The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice. J Ethnopharmacol. 2010;132:450-5 pubmed  publisher | 
|  | Borenstein X, Fiszman G, Blidner A, Vanzulli S, Jasnis M. Functional changes in murine mammary cancer cells elicited by CoCl2-induced hypoxia. Nitric Oxide. 2010;23:234-41 pubmed  publisher | 
|  | Shi J, Shao W, Yang D, Zhao L, Deng L, Wang X, et al . Hydrodynamics-based transfection of plasmid encoding receptor activator for nuclear factor kappa B-Fc protects against hepatic ischemia/reperfusion injury in mice. Liver Transpl. 2010;16:611-20 pubmed  publisher | 
|  | De Spiegelaere W, Cornillie P, van den Broeck W. Localization of erythropoietin in and around growing cartilage. Mol Cell Biochem. 2010;337:287-91 pubmed  publisher | 
|  | Wu Y, Jiang Y, Jin X, Lian L, Piao J, Wan Y, et al . Acanthoic acid, a diterpene in Acanthopanax koreanum, protects acetaminophen-induced hepatic toxicity in mice. Phytomedicine. 2010;17:475-9 pubmed  publisher | 
|  | Wu Y, Lian L, Jiang Y, Nan J. Hepatoprotective effects of salidroside on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice. J Pharm Pharmacol. 2009;61:1375-82 pubmed  publisher | 
|  | Ancuta E, Ancuta C, Cozma L, Iordache C, Anghelache Lupascu I, Anton E, et al . Tumor biomarkers in cervical cancer: focus on Ki-67 proliferation factor and E-cadherin expression. Rom J Morphol Embryol. 2009;50:413-8 pubmed | 
|  | Gravdal K, Halvorsen O, Haukaas S, Akslen L. Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer. Cancer Res. 2009;69:4708-15 pubmed  publisher | 
|  | Wu Y, Piao D, Han X, Nan J. Protective effects of salidroside against acetaminophen-induced toxicity in mice. Biol Pharm Bull. 2008;31:1523-9 pubmed |