product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
CXCR-4 (4G10) Antibody
catalog :
sc-53534
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G10
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; loading ...; fig 5a
Yang S, Wei J, Cui Y, Park G, Shah P, Deng Y, et al. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019;10:2782 pubmed publisher
  • western blot; human; loading ...; fig s2g
Lee S, Mayr C. Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 2019;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6c
Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
  • immunohistochemistry - frozen section; rat; loading ...; fig 6b
  • immunocytochemistry; rat; loading ...; fig 3f
  • western blot; rat; loading ...; fig 3e
Qin D, Yan Y, Hu B, Zhang W, Li H, Li X, et al. Wisp2 disruption represses Cxcr4 expression and inhibits BMSCs homing to injured liver. Oncotarget. 2017;8:98823-98836 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Li L, Baxter S, Gu N, Ji M, Zhan X. Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. J Cell Sci. 2017;130:1475-1485 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1I
  • western blot; human; fig 1C
Gravina G, Mancini A, Marampon F, Colapietro A, Delle Monache S, Sferra R, et al. The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma. J Hematol Oncol. 2017;10:5 pubmed publisher
  • immunocytochemistry; human; fig 5
Coke C, Scarlett K, Chetram M, Jones K, Sandifer B, Davis A, et al. Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression. J Biol Chem. 2016;291:9991-10005 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1
Zhu M, Guo J, Li W, Lu Y, Fu S, Xie X, et al. Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells. Oncotarget. 2015;6:12196-208 pubmed
Panda S, Dohare P, Jain S, Parikh N, Singla P, Mehdizadeh R, et al. Estrogen Treatment Reverses Prematurity-Induced Disruption in Cortical Interneuron Population. J Neurosci. 2018;38:7378-7391 pubmed publisher
Asumda F, Hatzistergos K, Dykxhoorn D, Jakubski S, Edwards J, Thomas E, et al. Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules. Differentiation. 2018;101:16-24 pubmed publisher
Sun Y, Mao X, Fan C, Liu C, Guo A, Guan S, et al. CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis. Tumour Biol. 2014;35:7765-73 pubmed publisher
Saravanakumar M, Devaraj H. Distribution and homing pattern of c-kit+ Sca-1+ CXCR4+ resident cardiac stem cells in neonatal, postnatal, and adult mouse heart. Cardiovasc Pathol. 2013;22:257-63 pubmed publisher
Albert S, Hourseau M, Halimi C, Serova M, Descatoire V, Barry B, et al. Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue. Oral Oncol. 2012;48:1263-71 pubmed publisher
Deschamps L, Bacha D, Rebours V, Mebarki M, Bretagnol F, Panis Y, et al. The expression of the hypoxia markers CA9 and CXCR4 is correlated with survival in patients with neuroendocrine tumours of the ileum. Neuroendocrinology. 2012;95:214-22 pubmed publisher
Reagan J, Foo T, Tracy Watson J, Jin W, Moed B, Zhang Z. Distinct phenotypes and regenerative potentials of early endothelial progenitor cells and outgrowth endothelial progenitor cells derived from umbilical cord blood. J Tissue Eng Regen Med. 2011;5:620-8 pubmed publisher
Bingham E, Cheng S, Woods Ignatoski K, Doherty G. Differentiation of human embryonic stem cells to a parathyroid-like phenotype. Stem Cells Dev. 2009;18:1071-80 pubmed publisher
product information
Catalog Number :
sc-53534
Product Name :
CXCR-4 (4G10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
4G10
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
CXCR-4
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA