product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
p-SC35 (SC-35) Antibody
catalog :
sc-53518
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
p-SC-35
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 3a
Ilik I, Malszycki M, Lübke A, Schade C, Meierhofer D, Aktas T. SON and SRRM2 are essential for nuclear speckle formation. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human
Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed publisher
Yandrapally S, Sarkar S, Banerjee S. HIV-1 Tat commandeers nuclear export of Rev-viral RNA complex by controlling hnRNPA2-mediated splicing. J Virol. 2023;97:e0104423 pubmed publisher
Han D, Longhini A, Zhang X, Hoang V, Wilson M, Kosik K. Dynamic assembly of the mRNA m6A methyltransferase complex is regulated by METTL3 phase separation. PLoS Biol. 2022;20:e3001535 pubmed publisher
Neueder A, Dumas A, Benjamin A, Bates G. Regulatory mechanisms of incomplete huntingtin mRNA splicing. Nat Commun. 2018;9:3955 pubmed publisher
Tu X, Gu Y, Ren G. miR-125a-3p targetedly regulates GIT1 expression to inhibit osteoblastic proliferation and differentiation. Exp Ther Med. 2016;12:4099-4106 pubmed publisher
Fritsch K, Mernberger M, Nist A, Stiewe T, Brehm A, Jacob R. Galectin-3 interacts with components of the nuclear ribonucleoprotein complex. BMC Cancer. 2016;16:502 pubmed publisher
Saha S, Choi H, Kim B, Dayem A, Yang G, Kim K, et al. KRT19 directly interacts with β-catenin/RAC1 complex to regulate NUMB-dependent NOTCH signaling pathway and breast cancer properties. Oncogene. 2017;36:332-349 pubmed publisher
Ohsaki Y, Kawai T, Yoshikawa Y, Cheng J, Jokitalo E, Fujimoto T. PML isoform II plays a critical role in nuclear lipid droplet formation. J Cell Biol. 2016;212:29-38 pubmed publisher
McCuaig R, Dunn J, Li J, Masch A, Knaute T, Schutkowski M, et al. PKC-Theta is a Novel SC35 Splicing Factor Regulator in Response to T Cell Activation. Front Immunol. 2015;6:562 pubmed publisher
Rodríguez Muñoz R, Cárdenas Aguayo M, Alemán V, Osorio B, Chávez González O, Rendon A, et al. Novel Nuclear Protein Complexes of Dystrophin 71 Isoforms in Rat Cultured Hippocampal GABAergic and Glutamatergic Neurons. PLoS ONE. 2015;10:e0137328 pubmed publisher
Stockley J, Markert E, Zhou Y, Robson C, Elliott D, Lindberg J, et al. The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7. Sci Rep. 2015;5:13426 pubmed publisher
Basei F, Meirelles G, Righetto G, Dos Santos Migueleti D, Smetana J, Kobarg J. New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing. Proteome Sci. 2015;13:11 pubmed publisher
Chang S, Chang W, Lu C, Tarn W. Alanine repeats influence protein localization in splicing speckles and paraspeckles. Nucleic Acids Res. 2014;42:13788-98 pubmed publisher
Choudhury R, Roy S, Tsai Y, Tripathy A, Graves L, Wang Z. The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration. Nat Commun. 2014;5:3078 pubmed publisher
Derlig K, Gießl A, Brandstätter J, Enz R, Dahlhaus R. Identification and characterisation of Simiate, a novel protein linked to the fragile X syndrome. PLoS ONE. 2013;8:e83007 pubmed publisher
Vivarelli S, Lenzken S, Ruepp M, Ranzini F, Maffioletti A, Alvarez R, et al. Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2. PLoS ONE. 2013;8:e61980 pubmed publisher
Werwein E, Dzuganova M, Usadel C, Klempnauer K. B-Myb switches from Cyclin/Cdk-dependent to Jnk- and p38 kinase-dependent phosphorylation and associates with SC35 bodies after UV stress. Cell Death Dis. 2013;4:e511 pubmed publisher
Kumar P, Kumar P, Lindberg L, Thirkill T, Ji J, Martsching L, et al. The MUC1 extracellular domain subunit is found in nuclear speckles and associates with spliceosomes. PLoS ONE. 2012;7:e42712 pubmed publisher
Kasper S, Breitenbuecher F, Heidel F, Hoffarth S, Markova B, Schuler M, et al. Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies. Blood Cancer J. 2012;2:e60 pubmed publisher
Nagarkatti Gude D, Jaimez R, Henderson S, Teves M, Zhang Z, Strauss J. Spag16, an axonemal central apparatus gene, encodes a male germ cell nuclear speckle protein that regulates SPAG16 mRNA expression. PLoS ONE. 2011;6:e20625 pubmed publisher
Qian W, Liang H, Shi J, Jin N, Grundke Iqbal I, Iqbal K, et al. Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A. Nucleic Acids Res. 2011;39:6161-71 pubmed publisher
Sytnikova Y, Kubarenko A, Sch fer A, Weber A, Niehrs C. Gadd45a is an RNA binding protein and is localized in nuclear speckles. PLoS ONE. 2011;6:e14500 pubmed publisher
Spiluttini B, Gu B, Belagal P, Smirnova A, Nguyen V, HEBERT C, et al. Splicing-independent recruitment of U1 snRNP to a transcription unit in living cells. J Cell Sci. 2010;123:2085-93 pubmed publisher
Xu M, Cook P. Similar active genes cluster in specialized transcription factories. J Cell Biol. 2008;181:615-23 pubmed publisher
Hivin P, Basbous J, Raymond F, Henaff D, Arpin André C, Robert Hebmann V, et al. The HBZ-SP1 isoform of human T-cell leukemia virus type I represses JunB activity by sequestration into nuclear bodies. Retrovirology. 2007;4:14 pubmed
product information
Catalog Number :
sc-53518
Product Name :
p-SC35 (SC-35) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Antigen Modification :
phosphorylation
Clone Name :
p-SC-35
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
SC35
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA