product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Smooth Muscle Actin (B4) Antibody
catalog :
sc-53142
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 34
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:200; fig 2r
Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, et al. Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. Nat Commun. 2022;13:4352 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2d
Hua X, Ge S, Zhang M, Mo F, Zhang L, Zhang J, et al. Pathogenic Roles of CXCL10 in Experimental Autoimmune Prostatitis by Modulating Macrophage Chemotaxis and Cytokine Secretion. Front Immunol. 2021;12:706027 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s1b
  • western blot; mouse; 1:1000; loading ...; fig 6c
Li B, He J, Lv H, Liu Y, Lv X, Zhang C, et al. c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. J Clin Invest. 2019;129:1167-1179 pubmed publisher
  • western blot; human; 1:2500; loading ...; fig 3a
Li T, Zhao J. Knockdown of elF3a inhibits TGF??1?induced extracellular matrix protein expression in keloid fibroblasts. Mol Med Rep. 2018;17:4057-4061 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Chen S, Wang Y, Zhang W, Dong M, Zhang J. Sclareolide enhances gemcitabine?induced cell death through mediating the NICD and Gli1 pathways in gemcitabine?resistant human pancreatic cancer. Mol Med Rep. 2017;15:1461-1470 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 8
Dinger K, Kasper P, Hucklenbruch Rother E, Vohlen C, Jobst E, Janoschek R, et al. Early-onset obesity dysregulates pulmonary adipocytokine/insulin signaling and induces asthma-like disease in mice. Sci Rep. 2016;6:24168 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100; fig 2
Wang X, Chen L, Liu J, Yan T, Wu G, Xia Y, et al. In vivo treatment of rat arterial adventitia with interleukin‑1β induces intimal proliferation via the JAK2/STAT3 signaling pathway. Mol Med Rep. 2016;13:3451-8 pubmed publisher
  • western blot; human; fig 6
Peiris Pagès M, Sotgia F, Lisanti M. Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells. Oncotarget. 2015;6:10728-45 pubmed
  • western blot; human
Chien P, Lin C, Hsiao L, Yang C. c-Src/Pyk2/EGFR/PI3K/Akt/CREB-activated pathway contributes to human cardiomyocyte hypertrophy: Role of COX-2 induction. Mol Cell Endocrinol. 2015;409:59-72 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Sánchez Alvarez R, Martinez Outschoorn U, Lin Z, Lamb R, Hulit J, Howell A, et al. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle. 2013;12:289-301 pubmed publisher
Wang Y, Qu Z, Fang Y, Chen Y, Peng J, Song J, et al. Chromosome territory reorganization through artificial chromosome fusion is compatible with cell fate determination and mouse development. Cell Discov. 2023;9:11 pubmed publisher
Liu Y, Yang Y, Suo Y, Li C, Chen M, Zheng S, et al. Inducible caspase-9 suicide gene under control of endogenous oct4 to safeguard mouse and human pluripotent stem cell therapy. Mol Ther Methods Clin Dev. 2022;24:332-341 pubmed publisher
Zhou W, Wang G, Li B, Qu J, Zhang Y. LncRNA APTR Promotes Uterine Leiomyoma Cell Proliferation by Targeting ERα to Activate the Wnt/β-Catenin Pathway. Front Oncol. 2021;11:536346 pubmed publisher
Sun L, Li J, Li E, Niu S, Qin Z, Zhi Q, et al. CRISPR/Cas9 mediated establishment of a human CSRP3 compound heterozygous knockout hESC line to model cardiomyopathy and heart failure. Stem Cell Res. 2020;49:102077 pubmed publisher
Han D, Kwon M, Lee S, Pleasure S, Yoon K. Non-cell autonomous promotion of astrogenesis at late embryonic stages by constitutive YAP activation. Sci Rep. 2020;10:7041 pubmed publisher
Zhang Y, Zhu W, He H, Fan B, Deng R, Hong Y, et al. Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair. Aging (Albany NY). 2019;11:12641-12660 pubmed publisher
Tang C, Lu C, Ji X, Ma L, Zhou Q, Xiong M, et al. Generation of two induced pluripotent stem cell (iPSC) lines from human breast milk using episomal reprogramming system. Stem Cell Res. 2019;39:101511 pubmed publisher
Xu L, Jing M, Yang L, Jin L, Gong P, Lu J, et al. The Alisma and Rhizoma decoction abates nonalcoholic steatohepatitis-associated liver injuries in mice by modulating oxidative stress and autophagy. BMC Complement Altern Med. 2019;19:92 pubmed publisher
Moon S, Im S, Kim N, Youn H, Park U, Kim J, et al. Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018;9:1118 pubmed publisher
Wang C, Li C, Lei W, Jiang J, Huang J, Zeng D. The association of neuron-derived orphan receptor 1 with pulmonary vascular remodeling in COPD patients. Int J Chron Obstruct Pulmon Dis. 2018;13:1177-1186 pubmed publisher
Rao S, Zhang X, Shi M, Xiao Y, Zhang Y, Wang Y, et al. Suberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats. J Thorac Dis. 2016;8:2485-2494 pubmed
Sun F, Hu K. Krüppel-Like Factor 4 Inhibits the Transforming Growth Factor-β1-Promoted Epithelial-to-Mesenchymal Transition via Downregulating Plasminogen Activator Inhibitor-1 in Lung Epithelial Cells. Dis Markers. 2015;2015:473742 pubmed publisher
Chien P, Lin C, Hsiao L, Yang C. Induction of HO-1 by carbon monoxide releasing molecule-2 attenuates thrombin-induced COX-2 expression and hypertrophy in primary human cardiomyocytes. Toxicol Appl Pharmacol. 2015;289:349-59 pubmed publisher
Tian L, Chen K, Cao J, Han Z, Gao L, Wang Y, et al. Galectin-3-induced oxidized low-density lipoprotein promotes the phenotypic transformation of vascular smooth muscle cells. Mol Med Rep. 2015;12:4995-5002 pubmed publisher
Breikaa R, Algandaby M, El Demerdash E, Abdel Naim A. Multimechanistic antifibrotic effect of biochanin a in rats: implications of proinflammatory and profibrogenic mediators. PLoS ONE. 2013;8:e69276 pubmed publisher
Lim R, Chan S, Tan J, Mockler J, Murphy S, Wallace E. Preterm human amnion epithelial cells have limited reparative potential. Placenta. 2013;34:486-92 pubmed publisher
Guido C, Whitaker Menezes D, Capparelli C, Balliet R, Lin Z, Pestell R, et al. Metabolic reprogramming of cancer-associated fibroblasts by TGF-? drives tumor growth: connecting TGF-? signaling with "Warburg-like" cancer metabolism and L-lactate production. Cell Cycle. 2012;11:3019-35 pubmed publisher
Zhang J, Huang C, Wu P, Yang J, Song T, Chen Y, et al. Differentiation induction of cardiac c-kit positive cells from rat heart into sinus node-like cells by 5-azacytidine. Tissue Cell. 2011;43:67-74 pubmed publisher
Zhang J, Huang C, Wu P, Yang J, Song T, Chen Y, et al. Cardiac stem cells differentiate into sinus node-like cells. Tohoku J Exp Med. 2010;222:113-20 pubmed
Martinez Outschoorn U, Pavlides S, Whitaker Menezes D, Daumer K, Milliman J, Chiavarina B, et al. Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors. Cell Cycle. 2010;9:2423-33 pubmed
Hecker M, Zaslona Z, Kwapiszewska G, Niess G, Zakrzewicz A, Hergenreider E, et al. Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2010;182:805-18 pubmed publisher
Legendre A, Froment P, Desmots S, Lecomte A, Habert R, Lemazurier E. An engineered 3D blood-testis barrier model for the assessment of reproductive toxicity potential. Biomaterials. 2010;31:4492-505 pubmed publisher
Qiao L, Xu Y, Liu X, Xie J, Wang J, Du C, et al. PKC promotes proliferation of airway smooth muscle cells by regulating cyclinD1 expression in asthmatic rats. Acta Pharmacol Sin. 2008;29:677-86 pubmed publisher
Wu X, Zhou Q, Huang L, Sun A, Wang K, Zou Y, et al. Ageing-exaggerated proliferation of vascular smooth muscle cells is related to attenuation of Jagged1 expression in endothelial cells. Cardiovasc Res. 2008;77:800-8 pubmed
product information
Catalog Number :
sc-53142
Product Name :
Smooth Muscle Actin (B4) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
B4
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Actin
Specificity :
mouse, rat, human, chicken
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA