product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
D2DR (B-10) Antibody
catalog :
sc-5303
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-10
reactivity :
human, mouse, rat, rabbit
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig 5b
Luessen D, Hinshaw T, Sun H, Howlett A, MARRS G, McCool B, et al. RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells. Neuropharmacology. 2016;110:297-307 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 6
Buzhdygan T, Lisinicchia J, Patel V, Johnson K, Neugebauer V, Paessler S, et al. Neuropsychological, Neurovirological and Neuroimmune Aspects of Abnormal GABAergic Transmission in HIV Infection. J Neuroimmune Pharmacol. 2016;11:279-93 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 5
Listos J, Baranowska-Bosiacka I, Wasik A, Talarek S, Tarnowski M, Listos P, et al. The adenosinergic system is involved in sensitization to morphine withdrawal signs in rats-neurochemical and molecular basis in dopaminergic system. Psychopharmacology (Berl). 2016;233:2383-97 pubmed publisher
  • western blot; mouse; 1:20; fig 2
Lauretti E, Di Meco A, Merali S, Pratico D. Chronic behavioral stress exaggerates motor deficit and neuroinflammation in the MPTP mouse model of Parkinson's disease. Transl Psychiatry. 2016;6:e733 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Bifsha P, Yang J, Fisher R, Drouin J. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. PLoS Genet. 2014;10:e1004863 pubmed publisher
  • western blot; mouse; 1:200; fig 4
Kurz A, Double K, Lastres-Becker I, Tozzi A, Tantucci M, Bockhart V, et al. A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice. PLoS ONE. 2010;5:e11464 pubmed publisher
  • western blot; mouse; 1:200
Sarantos M, Papanikolaou T, Ellerby L, Hughes R. Pizotifen Activates ERK and Provides Neuroprotection in vitro and in vivo in Models of Huntington's Disease. J Huntingtons Dis. 2012;1:195-210 pubmed publisher
  • immunohistochemistry; rabbit; 1:100
Parillo F, Maranesi M, Mignini F, Marinelli L, Di Stefano A, Boiti C, et al. Evidence for a dopamine intrinsic direct role in the regulation of the ovary reproductive function: in vitro study on rabbit corpora lutea. PLoS ONE. 2014;9:e104797 pubmed publisher
Salti A, Kummer K, Sadangi C, Dechant G, Saria A, El Rawas R. Social interaction reward decreases p38 activation in the nucleus accumbens shell of rats. Neuropharmacology. 2015;99:510-6 pubmed publisher
Prast J, Schardl A, Schwarzer C, Dechant G, Saria A, Zernig G. Reacquisition of cocaine conditioned place preference and its inhibition by previous social interaction preferentially affect D1-medium spiny neurons in the accumbens corridor. Front Behav Neurosci. 2014;8:317 pubmed publisher
BORCHERDING D, Hugo E, Idelman G, De Silva A, Richtand N, Loftus J, et al. Dopamine receptors in human adipocytes: expression and functions. PLoS ONE. 2011;6:e25537 pubmed publisher
Rocha L, Alonso-Vanegas M, Villeda-Hernandez J, Mújica M, Cisneros-Franco J, López-Gómez M, et al. Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy. Neurobiol Dis. 2012;45:499-507 pubmed publisher
Prast J, Schardl A, Sartori S, Singewald N, Saria A, Zernig G. Increased conditioned place preference for cocaine in high anxiety related behavior (HAB) mice is associated with an increased activation in the accumbens corridor. Front Behav Neurosci. 2014;8:441 pubmed publisher
Goodman R, Maltby M, Millar R, Hileman S, Nestor C, Whited B, et al. Evidence that dopamine acts via kisspeptin to hold GnRH pulse frequency in check in anestrous ewes. Endocrinology. 2012;153:5918-27 pubmed publisher
Stiles L, Zheng Y, Darlington C, Smith P. The effects of the D2 dopamine receptor antagonist, eticlopride, on attention following bilateral vestibular deafferentation in the rat. Neurosci Lett. 2012;506:193-7 pubmed publisher
Kurokawa K, Mizuno K, Ohkuma S. Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence. Alcohol Clin Exp Res. 2013;37:771-83 pubmed publisher
Delgado-Rosas F, Gomez R, Ferrero H, Gaytan F, Garcia-Velasco J, Simon C, et al. The effects of ergot and non-ergot-derived dopamine agonists in an experimental mouse model of endometriosis. Reproduction. 2011;142:745-55 pubmed publisher
Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies H, Sen N, et al. Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder. J Neurosci. 2010;30:6048-57 pubmed publisher
Stiles L, Zheng Y, Darlington C, Smith P. The D₂ dopamine receptor and locomotor hyperactivity following bilateral vestibular deafferentation in the rat. Behav Brain Res. 2012;227:150-8 pubmed publisher
Cuny T, Mohamed A, Graillon T, Roche C, Defilles C, Germanetti A, et al. Somatostatin receptor sst2 gene transfer in human prolactinomas in vitro: impact on sensitivity to dopamine, somatostatin and dopastatin, in the control of prolactin secretion. Mol Cell Endocrinol. 2012;355:106-13 pubmed publisher
Kurokawa K, Mizuno K, Ohkuma S. Possible involvement of type 1 inositol 1,4,5-trisphosphate receptors up-regulated by dopamine D1 and D2 receptors in mouse nucleus accumbens neurons in the development of methamphetamine-induced place preference. Neuroscience. 2012;227:22-9 pubmed publisher
Reyes S, Cottam V, Kirik D, Double K, Halliday G. Variability in neuronal expression of dopamine receptors and transporters in the substantia nigra. Mov Disord. 2013;28:1351-9 pubmed publisher
Drescher M, Cho W, Folbe A, Selvakumar D, Kewson D, Abu-Hamdan M, et al. An adenylyl cyclase signaling pathway predicts direct dopaminergic input to vestibular hair cells. Neuroscience. 2010;171:1054-74 pubmed publisher
Saveanu A, Muresan M, De Micco C, Taieb D, Germanetti A, Sebag F, et al. Expression of somatostatin receptors, dopamine D₂ receptors, noradrenaline transporters, and vesicular monoamine transporters in 52 pheochromocytomas and paragangliomas. Endocr Relat Cancer. 2011;18:287-300 pubmed publisher
Goold R, Hubank M, Hunt A, Holton J, Menon R, Revesz T, et al. Down-regulation of the dopamine receptor D2 in mice lacking ataxin 1. Hum Mol Genet. 2007;16:2122-34 pubmed
Bahcelioglu M, Gozil R, Take G, Elmas C, Oktem H, Kadioglu D, et al. Dose-related immunohistochemical and ultrastructural changes after oral methylphenidate administration in cerebrum and cerebellum of the rat. World J Biol Psychiatry. 2009;10:531-43 pubmed publisher
Montezinho L, Castro M, Duarte C, Penschuck S, Geraldes C, Mørk A. The interaction between dopamine D2-like and beta-adrenergic receptors in the prefrontal cortex is altered by mood-stabilizing agents. J Neurochem. 2006;96:1336-48 pubmed
Zou S, Li L, Pei L, Vukusic B, Van Tol H, Lee F, et al. Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity. J Neurosci. 2005;25:4385-95 pubmed
Otth C, Torres M, Ramirez A, Fernandez J, Castro M, Rauch M, et al. Novel identification of peripheral dopaminergic D2 receptor in male germ cells. J Cell Biochem. 2007;100:141-50 pubmed
product information
Product Name :
D2DR (B-10) Antibody
Gene Name :
DRD2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5303
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
D2DR
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
1-50 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA