product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PAI-1 (C-9) Antibody
catalog :
sc-5297
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-9
reactivity :
human, pig
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2a
Yan Y, Zhao W, Huang Y, Tong H, Xia Y, Jiang Q, et al. Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells. Sci Rep. 2017;7:46276 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2c
Ding Y, Zhang H, Lu A, Zhou Z, Zhong M, Shen D, et al. Effect of urokinase-type plasminogen activator system in gastric cancer with peritoneal metastasis. Oncol Lett. 2016;11:4208-4216 pubmed
  • immunocytochemistry; human; fig s1a
  • western blot; human; fig 3a
Huna A, Salmina K, Erenpreisa J, Vazquez Martin A, Krigerts J, Inashkina I, et al. Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide. Cell Cycle. 2015;14:2969-84 pubmed publisher
  • immunocytochemistry; pig; fig 1
Zhang W, Pei Y, Zhong L, Wen B, Cao S, Han J. Pluripotent and Metabolic Features of Two Types of Porcine iPSCs Derived from Defined Mouse and Human ES Cell Culture Conditions. PLoS ONE. 2015;10:e0124562 pubmed publisher
  • western blot; human
Feng Y, Wu H, Xu Y, Zhang Z, Liu T, Lin X, et al. Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-? signaling. J Biol Chem. 2014;289:2072-83 pubmed publisher
  • immunocytochemistry; human; 1:100
Sharma A, Diecke S, Zhang W, Lan F, He C, Mordwinkin N, et al. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem. 2013;288:18439-47 pubmed publisher
  • western blot; human
Wen X, Li Y, Hu K, Dai C, Liu Y. Hepatocyte growth factor receptor signaling mediates the anti-fibrotic action of 9-cis-retinoic acid in glomerular mesangial cells. Am J Pathol. 2005;167:947-57 pubmed
Sang Y, Cheng C, Zeng Y, Kang T. Snail promotes metastasis of nasopharyngeal carcinoma partly by down-regulating TEL2. Cancer Commun (Lond). 2018;38:58 pubmed publisher
Zhang X. Therapeutic effects of calcium dobesilate on diabetic nephropathy mediated through reduction of expression of PAI-1. Exp Ther Med. 2013;5:295-299 pubmed
Xiong M, Gong J, Liu Y, Xiang R, Tan X. Loss of vitamin D receptor in chronic kidney disease: a potential mechanism linking inflammation to epithelial-to-mesenchymal transition. Am J Physiol Renal Physiol. 2012;303:F1107-15 pubmed publisher
Loei H, Tan H, Lim T, Lim K, So J, Yeoh K, et al. Mining the gastric cancer secretome: identification of GRN as a potential diagnostic marker for early gastric cancer. J Proteome Res. 2012;11:1759-72 pubmed publisher
Shih Y, Takada Y, Lo S. Silencing of DLC1 upregulates PAI-1 expression and reduces migration in normal prostate cells. Mol Cancer Res. 2012;10:34-9 pubmed publisher
Wang D, Dai C, Li Y, Liu Y. Canonical Wnt/?-catenin signaling mediates transforming growth factor-?1-driven podocyte injury and proteinuria. Kidney Int. 2011;80:1159-1169 pubmed publisher
Zode G, Sethi A, Brun Zinkernagel A, Chang I, Clark A, Wordinger R. Transforming growth factor-?2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Mol Vis. 2011;17:1745-58 pubmed
He W, Tan R, Dai C, Li Y, Wang D, Hao S, et al. Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/beta-catenin signaling. J Biol Chem. 2010;285:24665-75 pubmed publisher
Zode G, Clark A, Wordinger R. Bone morphogenetic protein 4 inhibits TGF-beta2 stimulation of extracellular matrix proteins in optic nerve head cells: role of gremlin in ECM modulation. Glia. 2009;57:755-66 pubmed publisher
Park Y, Liu G, Lorne E, Zhao X, Wang J, Tsuruta Y, et al. PAI-1 inhibits neutrophil efferocytosis. Proc Natl Acad Sci U S A. 2008;105:11784-9 pubmed publisher
Yu X, Harris S, Levine A. The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res. 2006;66:4795-801 pubmed
Elvidge G, Glenny L, Appelhoff R, Ratcliffe P, Ragoussis J, Gleadle J. Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. J Biol Chem. 2006;281:15215-26 pubmed
Li Y, Wen X, Spataro B, Hu K, Dai C, Liu Y. hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists. J Am Soc Nephrol. 2006;17:54-65 pubmed
product information
Product Name :
PAI-1 (C-9) Antibody
Gene Name :
SERPINE1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5297
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
PAI-1
reactive species  :
human
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
24-158 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA