product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Clusterin-alpha (B-5) Antibody
catalog :
sc-5289
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-5
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 9b
Herring S, Moon H, Rawal P, Chhibber A, Zhao L. Brain clusterin protein isoforms and mitochondrial localization. elife. 2019;8: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Robbins J, Perfect L, Ribe E, Maresca M, Dangla Valls A, Foster E, et al. Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons. Front Neurosci. 2018;12:504 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig s1a
Lee J, Takahama S, Zhang G, Tomarev S, Ye Y. Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells. Nat Cell Biol. 2016;18:765-76 pubmed publisher
  • immunohistochemistry; human; 1:300
  • western blot; human
Xiu P, Xu Z, Liu F, Li Z, Li T, Zou F, et al. Downregulating sCLU enhances the sensitivity of hepatocellular carcinoma cells to gemcitabine by activating the intrinsic apoptosis pathway. Dig Dis Sci. 2014;59:1798-809 pubmed publisher
  • immunohistochemistry; human
Zhou M, Shen D, Head J, Chew E, Chévez Barrios P, Green W, et al. Ocular clusterin expression in von Hippel-Lindau disease. Mol Vis. 2007;13:2129-36 pubmed
Gomez E, Caamaño J, Corrales F, Diez C, Correia Álvarez E, Martin D, et al. Embryonic sex induces differential expression of proteins in bovine uterine fluid. J Proteome Res. 2013;12:1199-210 pubmed publisher
Aguilar Mahecha A, Cantin C, O Connor McCourt M, Nantel A, Basik M. Development of reverse phase protein microarrays for the validation of clusterin, a mid-abundant blood biomarker. Proteome Sci. 2009;7:15 pubmed publisher
Trougakos I, Lourda M, Antonelou M, Kletsas D, Gorgoulis V, Papassideri I, et al. Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clin Cancer Res. 2009;15:48-59 pubmed publisher
Jo H, Jia Y, Subramanian K, Hattori H, Luo H. Cancer cell-derived clusterin modulates the phosphatidylinositol 3'-kinase-Akt pathway through attenuation of insulin-like growth factor 1 during serum deprivation. Mol Cell Biol. 2008;28:4285-99 pubmed publisher
Suuronen T, Nuutinen T, Ryhanen T, Kaarniranta K, Salminen A. Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells. Biochem Biophys Res Commun. 2007;357:397-401 pubmed
Nuutinen T, Huuskonen J, Suuronen T, Ojala J, Miettinen R, Salminen A. Amyloid-beta 1-42 induced endocytosis and clusterin/apoJ protein accumulation in cultured human astrocytes. Neurochem Int. 2007;50:540-7 pubmed
Horner Glister E, Maleki Dizaji M, Guerin C, Johnson S, Styles J, White I. Influence of oestradiol and tamoxifen on oestrogen receptors-alpha and -beta protein degradation and non-genomic signalling pathways in uterine and breast carcinoma cells. J Mol Endocrinol. 2005;35:421-32 pubmed
Nuutinen T, Suuronen T, Kyrylenko S, Huuskonen J, Salminen A. Induction of clusterin/apoJ expression by histone deacetylase inhibitors in neural cells. Neurochem Int. 2005;47:528-38 pubmed
product information
Product Name :
Clusterin-alpha (B-5) Antibody
Gene Name :
CLU
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5289
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Clusterin-alpha
reactive species  :
human
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
C-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA