product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Wee 1 (B-11) Antibody
catalog :
sc-5285
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-11
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3
Kim M, Caplen N, Chakka S, Hernandez L, House C, Pongas G, et al. Identification of therapeutic targets applicable to clinical strategies in ovarian cancer. BMC Cancer. 2016;16:678 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 6d
  • western blot; human; 1:1000
Huang Y, Peng W, Furuuchi N, DuHadaway J, Jimbo M, Pirritano A, et al. Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy. Oncotarget. 2016;7:21812-24 pubmed publisher
  • western blot; human; 1:1000; fig 6
Soriano A, París Coderch L, Jubierre L, Martínez A, Zhou X, Piskareva O, et al. MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes. Oncotarget. 2016;7:9271-87 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Hu J, Lu J, Lian G, Zhang J, Hecht J, Sheen V. Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS ONE. 2014;9:e89352 pubmed publisher
  • western blot; human; 1:200
Yu Y, Munger K. Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis. Virology. 2013;446:251-9 pubmed publisher
Hayashi Y, Fujimura A, Kato K, Udagawa R, Hirota T, Kimura K. Nucleolar integrity during interphase supports faithful Cdk1 activation and mitotic entry. Sci Adv. 2018;4:eaap7777 pubmed publisher
Liu K, Fang L, Sun H, Pan Z, Zhang J, Chen J, et al. Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo. Mol Cancer Ther. 2018;17:988-1002 pubmed publisher
Herling C, Abedpour N, Weiss J, Schmitt A, Jachimowicz R, Merkel O, et al. Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia. Nat Commun. 2018;9:727 pubmed publisher
Mulay A, Akram K, Williams D, Armes H, Russell C, Hood D, et al. An in vitro model of murine middle ear epithelium. Dis Model Mech. 2016;9:1405-1417 pubmed
Magnussen G, Hellesylt E, Nesland J, Trope C, Flørenes V, Holm R. High expression of wee1 is associated with malignancy in vulvar squamous cell carcinoma patients. BMC Cancer. 2013;13:288 pubmed publisher
Bhattacharya A, Schmitz U, Wolkenhauer O, Schönherr M, Raatz Y, Kunz M. Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma. Oncogene. 2013;32:3175-83 pubmed publisher
Magnussen G, Holm R, Emilsen E, Rosnes A, Slipicevic A, Flørenes V. High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy. PLoS ONE. 2012;7:e38254 pubmed publisher
Lian G, Lu J, Hu J, Zhang J, Cross S, Ferland R, et al. Filamin a regulates neural progenitor proliferation and cortical size through Wee1-dependent Cdk1 phosphorylation. J Neurosci. 2012;32:7672-84 pubmed publisher
Tibes R, Bogenberger J, Chaudhuri L, Hagelstrom R, Chow D, Buechel M, et al. RNAi screening of the kinome with cytarabine in leukemias. Blood. 2012;119:2863-72 pubmed publisher
Kamata M, Watanabe N, Nagaoka Y, Chen I. Human immunodeficiency virus type 1 Vpr binds to the N lobe of the Wee1 kinase domain and enhances kinase activity for CDC2. J Virol. 2008;82:5672-82 pubmed publisher
Whittaker S, te Poele R, Chan F, Linardopoulos S, Walton M, Garrett M, et al. The cyclin-dependent kinase inhibitor seliciclib (R-roscovitine; CYC202) decreases the expression of mitotic control genes and prevents entry into mitosis. Cell Cycle. 2007;6:3114-31 pubmed
product information
Product Name :
Wee 1 (B-11) Antibody
Gene Name :
WEE1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5285
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Wee 1
reactive species  :
human
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
347-646 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA