product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
DNA-PKCS (G-4) Antibody
catalog :
sc-5282
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G-4
reactivity :
African green monkey, human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4
Young L, Marzio A, Pérez Durán P, Reid D, Meredith D, Roberti D, et al. TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response. Cell Rep. 2015;13:451-459 pubmed publisher
  • western blot; mouse; 1:3000; fig 4
Liu X, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs R, et al. LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. Nat Commun. 2015;6:8325 pubmed publisher
  • immunocytochemistry; African green monkey; fig 4c
  • western blot; African green monkey; fig 4a
Sowd G, Mody D, Eggold J, Cortez D, Friedman K, Fanning E. SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products. PLoS Pathog. 2014;10:e1004536 pubmed publisher
  • immunohistochemistry; human; 1:50
Saini R, Attarha S, da Silva Santos C, Kolakowska J, Funa K, Souchelnytskyi S. Proteomics of dedifferentiation of SK-N-BE2 neuroblastoma cells. Biochem Biophys Res Commun. 2014;454:202-9 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Owonikoko T, Zhang G, Deng X, Rossi M, Switchenko J, Doho G, et al. Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer. Cancer Med. 2014;3:1579-94 pubmed publisher
Chien J, Tabet E, Pinkham K, da Hora C, Chang J, Lin S, et al. A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo. Nucleic Acids Res. 2020;48:e100 pubmed publisher
Burrage L, Reynolds J, Baratang N, Phillips J, Wegner J, McFarquhar A, et al. Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. Am J Hum Genet. 2019;104:422-438 pubmed publisher
Ashraf R, Hamidullah -, Hasanain M, Pandey P, Maheshwari M, Singh L, et al. Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications. Sci Rep. 2017;7:45287 pubmed publisher
Suman S, Rodriguez O, Winters T, Fornace A, Albanese C, Datta K. Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production. Aging (Albany NY). 2013;5:607-22 pubmed
Garcia I, Cosio G, Lizarraga F, Martinez Ruiz G, Melendez Zajgla J, Ceballos G, et al. Bcl-3 regulates UVB-induced apoptosis. Hum Cell. 2013;26:47-55 pubmed publisher
Haro K, Sheth A, Scheinberg D. Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells. PLoS ONE. 2012;7:e48841 pubmed publisher
Lu H, Hu L, Li T, Lahiri S, Shen C, Wason M, et al. A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells. J Biol Chem. 2012;287:43720-9 pubmed publisher
Zhang J, De Toledo S, Pandey B, Guo G, Pain D, Li H, et al. Role of the translationally controlled tumor protein in DNA damage sensing and repair. Proc Natl Acad Sci U S A. 2012;109:E926-33 pubmed publisher
Olsen B, Wang S, Svenstrup T, Chen B, Guerra B. Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage. BMC Mol Biol. 2012;13:7 pubmed publisher
Smith M, Bayless A, Goddard E, Davido D. CK2 inhibitors increase the sensitivity of HSV-1 to interferon-?. Antiviral Res. 2011;91:259-66 pubmed publisher
Medunjanin S, Weinert S, Schmeisser A, Mayer D, Braun Dullaeus R. Interaction of the double-strand break repair kinase DNA-PK and estrogen receptor-alpha. Mol Biol Cell. 2010;21:1620-8 pubmed publisher
Medunjanin S, Weinert S, Poitz D, Schmeisser A, Strasser R, Braun Dullaeus R. Transcriptional activation of DNA-dependent protein kinase catalytic subunit gene expression by oestrogen receptor-alpha. EMBO Rep. 2010;11:208-13 pubmed publisher
Hilliard J, COOPER A, Slusser J, Davido D. A flow cytometric assay for the study of E3 ubiquitin ligase activity. Cytometry A. 2009;75:634-41 pubmed publisher
Rivera Calzada A, Maman J, Maman J, Spagnolo L, Pearl L, Llorca O. Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs). Structure. 2005;13:243-55 pubmed
product information
Product Name :
DNA-PKCS (G-4) Antibody
Gene Name :
PRKDC
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5282
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
DNA-PKCS
reactive species  :
human
Application :
WB, IP, IF, ELISA
Epitope :
2965-4127 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA